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Rational and irrational. Remarks on the clinical gendering of language in psychoanalysis.

This paper extends Hartmann's skepticism about the heuristic value of the polarized terms "rational" and "irrational" lest they be used for future theory building. Clinically--now, as in ancient times--a close correlation exists between this polarity and that of common-parlance value judgments--"masculine/rational/positive" and "feminine/irrational/negative." Primitive ambivalence concerning the repudiation of femininity is explored here in both sexes. A suggestion is raised that it may be the female's capacity for pregnancy, rather than the infantile reaction to genital difference, that is the most vital underpinning of the age-old negative view of women.

Adult↗

Minimizing acarians and house dust in the tropics.

Dust collection and mite isolation by Furumizo's method occurred in 33 homes on days 0 and 14. The first application of Paragerm AK (23 homes) or placebo aerosol (ten homes) was done after vacuuming on day 14. The second (final) spraying occurred on day 28, immediately after vacuuming. Vacuum collections without spraying were done on days 56 and 84 in this randomized double-blind trial. With Paragerm, dust volume fell to 80.3% of initial levels by day 28, remained low at 87.9% (P < .05) on day 56, and then rose to 115.9% by day 84. In control homes, comparative dust values were 89.0%, 103.7%, and 109.9%. With Paragerm, mite concentration decreased to 70.8% by day 28 (P < .01), to 65% at day 56 (P < .025), and continued to fall to 47.7% by day 84 (P < .05). With control aerosol, mite numbers rose compared with initial values: 119.1% at day 28, 227.2% at day 56, and 125.1% at day 84. No adverse effects were observed in Paragerm homes besides odor (70% complained). The two asthmatic occupants improved symptomatically and took less medication following the Paragerm. In conclusion, Paragerm, used over 40 years in Europe, is an effective, nontoxic acaricide in Hawaii, acting promptly and for at least 2 months. It was also associated with diminished dust volume, important in nondust allergy.

Aerosols↗

Elder health programs in state health agencies.

Due to the rapid rise in the population of those aged 65 and older, public health programs that target this group merit special attention. State health agencies can play leading roles in providing and coordinating elder health programs by identifying needs and formulating guidelines in collaboration with federal, local, and private organizations. The Massachusetts Department of Public Health initiated the Elder Health Programs Unit in 1988, with a mission to assist elders in maintaining their highest level of functional status in community settings and to provide opportunities for older adults to take greater responsibility for their own health. The extent of involvement in elder health programming of other state health agencies outside of Massachusetts is not well documented. Through the distribution of a national survey, we set out to determine how many state health agencies offer elder health services.

Aged↗

The pregnant mother and the body image of the daughter.

This paper is about the place of the pregnant maternal body in the developing body image of the daughter. Adult examples from two cases are offered to demonstrate its lingering effects on the women's perceptions of their shapes, sizes, abdomens, breasts, and buttocks. Attention is drawn to its neglect in our formulations. It is suggested that the whole exterior of the body of the female is as important to her as the outer and inner genitals, and makes a vital contribution to the final shape of her gender role identity.

Adult↗

Functional mapping of CD11b/CD18 epitopes important in neutrophil-epithelial interactions: a central role of the I domain.

In the intestine, lung, and urinary tract, neutrophil (polymorphonuclear leukocyte, PMN) transepithelial migration is dependent on the leukocyte beta2 integrin CD11b/CD18. While the regions of CD11b involved in recognition of several soluble ligands are known, those that mediate PMN-epithelial interactions have not been investigated. In this study, mAbs reactive with four extracellular regions on CD11b, the NH2-terminal region, I (inserted) domain, cation-binding region, and region proximal to the transmembrane domain (C domain), were analyzed for the ability to block CD11b/CD18-mediated interactions with T84 intestinal epithelial cells. In such a manner, epitope mapping was applied to the complex interactions between CD11b/CD18 and a cell-based ligand system. I domain Abs strongly inhibited both adhesion of PMN to epithelial cells and PMN migration across T84 epithelial monolayers. However, the profile of inhibition was distinct from that of other known ligands of CD11b/CD18. CBRM1/32, an Ab to a discontinuous epitope residing within the NH2- and cation-binding domains, strongly inhibited both adhesion and transmigration responses. C domain Abs had minimal effects on adhesion and transmigration. These findings appear applicable to other epithelia, since similar results were obtained in transmigration experiments with CF15 human airway epithelial cells. Finally, Ab inhibition profiles were confirmed with adhesion assays of isolated epithelial cells to purified CD11b/CD18. These findings demonstrate the central role of the I domain and the participation of a discontinuous region shared by the NH2- and cation-binding domains in mediating PMN-adhesive interactions with epithelial cells.

Antibodies, Monoclonal↗

Related issues in childbearing and work: two clinical studies of professional women.

A common structure is described in two women's experience in central aspects of their professions and in their thoughts and feelings about motherhood. For example, a scientist's fascination in experimentation with cells in developing embryos is linked with wishes to experiment with the fertility of her own body, and an artist describes connections between the conflicts in finishing and showing her paintings and the conflicts in allowing her infant to separate from her body in the birth process. Historical clinical material from once-weekly psychoanalytically oriented psychotherapy is used to trace some of the dynamics common to the major themes.

Attitude↗