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Accuracy of outpatient endometrial biopsy in the diagnosis of endometrial hyperplasia.

BACKGROUND: To determine the accuracy of outpatient endometrial biopsy in diagnosing endometrial hyperplasia in women with abnormal uterine bleeding. DESIGN: Systematic quantitative review of published medical literature. DATA SOURCES: Relevant papers were identified through electronic scanning of MEDLINE (1980-1999) and EMBASE (1980-1999), manual searching of bibliography of known primary and review articles and contact with manufacturers. REVIEW METHODS: Studies were selected if accuracy of outpatient endometrial biopsy, in women with abnormal pre or postmenopausal uterine bleeding, was estimated compared to a reference standard, which was endometrial histology obtained by tissue sampling under anesthesia. Quality assessment and data extraction were performed in duplicate. Diagnostic accuracy was determined by pooled likelihood ratios (LR) for positive and negative test results for endometrial hyperplasia. RESULTS: There were 881 subjects in 8 diagnostic evaluations reported in 6 primary studies. Postmenopausal women represented 25% of the participants studied. There were 43 patients in whom outpatient sampling was inadequate. A positive test result on outpatient biopsy diagnosed endometrial hyperplasia with a pooled LR of 12.0 (95% CI 7.8-18.6) while a negative test result had a pooled LR of 0.2 (95% CI 0.1-0.3). With a positive test result, the posttest probability of endometrial hyperplasia was 57.7% (95% CI 41.1%-72.7%) while it was 2.2% (95% CI 0.9%-4.1%) with a negative test. CONCLUSION: Outpatient endometrial biopsy has modest accuracy in diagnosing endometrial hyperplasia. Therefore, additional endometrial assessment should be undertaken, especially if symptoms persist or intrauterine structural abnormalities are suspected.

Ambulatory Care↗

Meta-accuracy among acquainted individuals: a social relations analysis of interpersonal perception and metaperception.

Meta-accuracy, knowing how others view the self, was examined using the Social Relations Model. Fifteen groups of 4-6 acquainted individuals gave self-ratings, perceptions of other group members, and estimated others' perceptions of self (metaperceptions) on the Big Five and Interesting. Individuals also rated liking and metaperceptions of liking. Trait perceptions were consensual, and self-other agreement emerged for most traits. Affect judgments were entirely relational; individuals differentiated among targets. Trait metaperceptions were dominated by perceiver variance. Individuals differed in the impression they believed others generally held about them. Affect metaperceptions, however, were relational in nature. Correlations between perceptions and metaperceptions assessed 2 types of meta-accuracy. Generalised meta-accuracy was obtained for some trait ratings. Affect judgments revealed significant dyadic meta-accuracy.

Affect↗

Confidence and accuracy in person perception: do we know what we think we know about our relationship partners?

A cross-sectional study of dating partners and a longitudinal study of college roommates revealed that the confidence and accuracy of their impressions were often dissociated. For example, relationship length and degree of involvement tended to increase the confidence of people's impressions, but neither variable consistently increased the accuracy of their impressions of their partners' sexual histories, activity preferences, and so on. A third study showed that relationship length and involvement increased the richness of impressions, and richness fostered confidence. The authors conclude that although confidence-accuracy dissociations are surely problematic in some instances, their apparent pervasiveness raises the possibility that confidence may sometimes contribute to relationship quality even when it is unrelated to accuracy.

Adolescent↗

Accuracy of judging time to arrival: effects of modality, trajectory, and gender.

Observers' accuracy in using time-to-arrival (Ta) information was examined in 4 experiments. The issues included use of visual vs. acoustic Ta information, use of acoustic Ta information by blind Ss, use of Ta information controlling for velocity, and effects of angle of approach and arrival time on judgment accuracy. Visual information was used more efficiently than audiovisual and auditory information. Blind Ss used acoustical approach information as accurately as sighted Ss used visual information. Radial, oblique, and transverse orientations were used to examine effects of approach trajectory. Radial events were underestimated, whereas the more accurate transverse approach was likely to be overestimated. Oblique angle events yielded intermediate accuracies implying a spatiotemporal anisotropy. Women underestimated Ta more than did men. Possible reasons for Ss' judgment accuracy, including linear vs. nonlinear optical changes and relation to spatial skills and experience, were discussed.

Adult↗

Response time and accuracy revisited: converging support for the interactive race model.

The interactive race model embodies 2 central claims: that divided attention is best described as a race between separately processed codes and that the 2 types of design contingency to which the model is sensitive affect different processing stages. Previous support for the model has come from a series of redundant-target tasks examining reaction time (RT) (J.T. Mordkoff & S. Yantis, 1991). We tested both central claims using near-threshold, accuracy tasks. This approach capitalizes on a known difference between RT and accuracy measures: that (in simple tasks) accuracy is sensitive only to perceptual manipulations, whereas RT is affected by both perceptual and postperceptual factors (J.L. Santee & H.E. Egeth, 1982). The results from 3 experiments provide converging support for the proposed loci of the 2 contingency-sensitive mechanisms within the interactive race model, as well as additional evidence concerning the differential sensitivities of RT and accuracy measures.

Adult↗

Do reaction time and accuracy measure the same aspects of letter recognition?

Two experiments indicate that reaction time and accuracy are not always equivalent measures of the underlying processes involved in the recognition of visually presented letters. In conjunction with the results of previous work, our research suggests the following generalizations: (a) Under data-limited viewing conditions (the short exposure durations of the typical tachistoscopic task), response accuracy is sensitive to early perceptual interference between target and noise items, whereas reaction time is more sensitive to later processes involved in response interference. (b) Under resource-limited viewing conditions (the long exposure durations of the typical reaction time task), both accuracy and reaction time appear to be sensitive to processes occurring in the later rather than the earlier stages of processing. Since the two dependent measures do not always reflect the same perceptual processes, we suggest that the convergence of reaction time and accuracy within the context of a specific information processing model should be demonstrated empirically rather than assumed a priori.

Attention↗

Accuracy of feeling-of-knowing judgments for predicting perceptual identification and relearning.

The feeding of knowing refers to predictions about subsequent memory performance on previously nonrecalled items. The most frequently investigated type of subsequent performance has been recognition. The present research explored predictive accuracy with two new feeling-of-knowing criterion tests (in addition to recognition): relearning and perceptual identification. In two experiments, people attempted to recall the answers to general-information questions such as, "What is the capital of Australia?", then made feeling-of-knowing predictions for all nonrecalled answers, and finally had a criterion test to assess the accuracy of the feeling-of-knowing predictions. Experiment 1 demonstrated that perceptual identification can be employed successfully as a criterion test for the feeling of knowing. This opens a new way for metamemory research via perception. Moreover, the feeling-of-knowing accuracy for predicting perceptual identification was not significantly correlated with the feeling-of-knowing accuracy for predicting recognition, in accord with the idea that these two tests assess memory differently. Experiment 2 demonstrated that relearning performance can also be predicted by feeling-of-knowing judgments. Both experiments showed that there is a positive relationship between the feeling of knowing and the amount of time elapsing before a memory search is terminated during recall. Further analyses showed that this relationship is substantial for nonrecalled items for which the person did not guess an answer (omission errors), but the relationship is null or negative for nonrecalled items that the person guessed incorrectly (commission errors). Several theoretical mechanisms that may underlie the feeling of knowing are proposed.

Humans↗

Structure and process in semantic memory: new evidence based on speed-accuracy decomposition.

Reaction-time and accuracy data obtained from studies of sentence verification have not been rich enough to answer certain important theoretical questions about structures and processes in human semantic memory. However, a new technique called speed-accuracy decomposition (Meyer, Irwin, Osman, & Kounios, 1986) may help solve this problem. The technique allows intermediate products of sentence verification to be analyzed more precisely. Three experiments with speed-accuracy decomposition indicate that verification processes produce useful partial information before they are completed. Such information appears to accumulate continuously at a rate whose magnitude depends on the degree of relatedness between semantic categories. This outcome is consistent with continuous computational (e.g., semantic-feature comparison) models of semantic memory. An analysis of reaction-time minima suggests that a discrete all-or-none search process may also contribute at least occasionally to sentence verification. Further details regarding the nature of these processes and the memory structures on which they operate can be inferred from additional results obtained through speed-accuracy decomposition.

Humans↗

Eyewitness memory and aging: predictors of accuracy in recall and person recognition.

This study examined adult age differences in identification accuracy, confidence, and verbal recall of crime films. A total of 120 Ss in 3 adult age groups watched 2 crime films that contained characters varying in role and visibility. Results suggested a modest negative relationship between age and identification accuracy but no age differences in recall of main points or details. Education and self-reported health positively predicted verbal recall, but higher education was associated with lower identification accuracy. No age differences were found in confidence or in the relationship between confidence and accuracy.

Adult↗

The effect of the cognitive interview on face identification accuracy: release from verbal overshadowing.

Three experiments tested the effect of verbal description on face identification accuracy. Based on verbal overshadowing research, it was predicted that enhancing verbal description of a face would reduce subsequent face identification accuracy. Experiment 1 tested and confirmed this hypothesis using the cognitive interview to enhance verbal description; face identification accuracy was reduced significantly following the cognitive interview, compared with a standard police interview. Experiments 2 and 3 tested and confirmed the hypothesis that verbal overshadowing would be reduced when a delay is inserted between verbal description and face identification, hence resulting in "release from verbal overshadowing." These results suggest that in the verbal overshadowing task, the verbal description does not overwrite the visually based representation of the face in memory but rather makes it less accessible at the time of face identification. The cognitive interview reduces face identification accuracy only when the identification follows description immediately--a rare situation in real criminal cases.

Adult↗

Accuracy and bias in the perception of the partner in a close relationship.

Partners in close relationships can be both accurate and biased in their perceptions of each other. Moreover, sometimes a bias can lead to accuracy. The authors describe a paradigm for the simultaneous measurement of accuracy and bias in 2-person relationships. One prevalent bias in close relationships is assumed similarity: Does the person think that his or her partner sees the world as he or she does? In a study of 238 dating and married heterosexual couples, the authors found evidence for both bias and accuracy: the bias effects were considerably stronger, especially when the measure was linked to the relationship. They found little or no evidence for gender differences in accuracy and bias.

Courtship↗

Monitoring and control processes in the strategic regulation of memory accuracy.

When people are allowed freedom to volunteer or withhold information, they can enhance the accuracy of their memory reports substantially relative to forced-report performance. A theoretical framework addressing the strategic regulation of memory reporting is put forward that delineates the mediating role of metamemorial monitoring and control processes. Although the enhancement of memory accuracy is generally accompanied by a reduction in memory quantity, experimental and simulation results indicate that both of these effects depend critically on (a) accuracy incentive and (b) monitoring effectiveness. The results are discussed with regard to the contribution of meta-memory processes to memory performance, and a general methodology is proposed that incorporates these processes into the assessment of memory-accuracy and memory-quantity performance.

Achievement↗

Understanding the delayed-keyword effect on metacomprehension accuracy.

The typical finding from research on metacomprehension is that accuracy is quite low. However, recent studies have shown robust accuracy improvements when judgments follow certain generation tasks (summarizing or keyword listing) but only when these tasks are performed at a delay rather than immediately after reading (K. W. Thiede & M. C. M. Anderson, 2003; K. W. Thiede, M. C. M. Anderson, & D. Therriault, 2003). The delayed and immediate conditions in these studies confounded the delay between reading and generation tasks with other task lags, including the lag between multiple generation tasks and the lag between generation tasks and judgments. The first 2 experiments disentangle these confounded manipulations and provide clear evidence that the delay between reading and keyword generation is the only lag critical to improving metacomprehension accuracy. The 3rd and 4th experiments show that not all delayed tasks produce improvements and suggest that delayed generative tasks provide necessary diagnostic cues about comprehension for improving metacomprehension accuracy.

Cognition↗

I don't think that's what really happened: the effect of cross-examination on the accuracy of children's reports.

In the courtroom, child witnesses must undergo cross-examination. Prior research has shown that children change their original testimony under cross-examination, but the effect of these changes on the accuracy of children's testimony is unknown. The authors examined the effect of cross-examination on the accuracy of 5- and 6-year-old children's (N=46) reports of a contrived event. Consistent with prior research, children made changes to their original responses during cross-examination. Furthermore, these changes occurred irrespective of original accuracy. Finally, prior exposure to misleading information did not affect children's responses to cross-examination. Even children with no prior exposure to misinformation altered their original responses, decreasing their ultimate levels of accuracy. These findings demonstrate that cross-examination style questioning is inappropriate for young children.

Child↗

Precision and accuracy in a metabolic monitor for indirect calorimetry.

OBJECTIVE: To determine within-machine and between-machine precision (reproducibility) and accuracy, of the Deltatrac Mk 1 Metabolic Monitor. DESIGN: Within-machine and between-machine comparison for gas exchange (VO2 and VCO2), respiratory quotient (RQ) and energy expenditure (EE). SUBJECTS: 3 Deltatrac Mk 1 Metabolic Monitors. METHODS: Within-machine and between-machine reproducibility were assessed by five successive 10 min gas infusion tests in each machine. Accuracy was assessed by measuring independently the gas content of the infusion mixture. The Deltatrac flowmeters were evaluated by further infusion tests. RESULTS: Within-study reproducibility was < 1 ml/min for VCO2, < 2.5 ml/min for VO2, < 5 kcal/d for EE and < 0.01 for RQ. Between-study reproducibility was < 0.2% for RQ, < 1% for VCO2 and < 2% for VO2 and EE. Between-machine reproducibility was < 0.1% for RQ and < 1% for VO2, VCO2 and EE. Accuracy in all three machines was within 3% for VO2, VCO2 and EE, and within 0.2% for RQ. CONCLUSIONS: The Deltatrac Mk 1 is a very precise metabolic monitor, and is accurate within 3% for gas exchange and EE. RQ is measured with greatest reproducibility and accuracy (within 0.2%), making the monitor particularly suitable for studies of substrate utilisation.

Adult↗

Eyetrack (ET) vs the conventional paper record (CPR): a study comparing the accuracy and speed of data retrieval from glaucoma patient records.

PURPOSE: To compare patient data retrieval between electronic patient record systems (Eyetrack) and conventional paper records (CPRs). METHODS: A total of 20 long term glaucoma patient records held on Eyetrack were randomised into two collections with 10 CPRs and 10 Eyetrack records in each collection. The Eyetrack records of one collection were the CPRs of the other collection and vice versa. Four doctors, as two groups, were assessed on a separate collection of records. The time taken to answer 10 questions and the accuracy were assessed. Comparison was made of the answers between the two formats. A month later each group was assessed on the 10 CPRs of the other collection. An expert Eyetrack user was assessed on only the 20 Eyetrack notes. Comparison was made between the 20 CPRs the doctors were assessed on and the 20 eyetrack records. RESULTS: In the first comparison, the mean time for all the doctors to answer the questions on a CPR was 324.4(+/-106.0) s compared to 104.8(+/-34.0) s for Eyetrack(Mann-Whitney, P<0.01). Mean accuracy for a CPR was 84.0%(+/-13.0%) compared to 98.0%(+/-4.0%) for Eyetrack(Mann-Whitney, P<0.01). Comparing the expert Eyetrack user with the CPR showed a mean time for Eyetrack of 96.6(+/-34.8) s compared with 283.7(+/-63.9) s for CPR(Mann-Whitney, P<0.0001). Mean accuracy for Eyetrack was 97.5%(+/-7.2%) compared to 82.0%(+/-8.7%) for CPRs(Mann-Whitney, P<0.0001). CONCLUSIONS: An improvement of 3 min 40 s per record was observed with Eyetrack. Accuracy was also improved. Similar results were also found comparing an expert Eyetrack user with CPRs.

Glaucoma↗

Accuracy of the OMRON M4 automatic blood pressure measuring device.

Despite widespread use of the automatic blood pressure (BP) measuring device OMRON M4, there is little formal validation on its accuracy. A study was conducted to assess the accuracy of the OMRON M4 compared with the true indirect BP measured by mercury sphygmomanometer (MS). A rapid method for the evaluation of automatic blood pressure measurement devices (READ) was applied for this study. The READ is based on numerous BP measurements at rest and during a standardised postural challenge in a small number of subjects who exhibit a wide range of BPs. Blood pressure measurements were done in supine position for 10 min followed by head-up tilt for 30 min and again supine for 10 min. The automatic device (AU) and the MS were connected to one arm-cuff by means of a T connector. A stethoscope with dual sets of ear-pieces was used for duplicate MS measurements (MS1 and MS2). The MS1, MS2 and AU measurements were taken simultaneously in a blinded manner. Three units of the automatic instrument were evaluated. An average of 111 measurements per unit were performed, every BP category being present in >/=15 MS measurements. The differences between MS1 and MS2 measurements (DeltaBP: MS1-MS2) were utilized to assess the consistency of true indirect BP and the differences between AU and MS measurements (DeltaBP:AU-MS2) were utilized to assess the accuracy of the AU. The following characteristics of the OMRON M4 were assessed: (1) grade of accuracy, (2) aberration pattern, (3) consistency of the aberration-pattern, and (4) correlation between levels of BP and DeltaBP: AU-MS. For MS paired readings, 92-100% of systolic and 99-100% of diastolic readings fell within 5 mm Hg difference range, that is consistent with a British Hypertension Society grade A of both. For AU compared to MS2, 29-64% of systolic and 73-94% of diastolic readings fell within 5 mm Hg and 49-86% of systolic and 86-99% of diastolic readings fell within 10 mm Hg and the devices qualified C, D and C, respectively. All devices exhibited irregular and inconsistent aberration patterns, making the design of correction formulas impractical. In conclusion, the OMRON M4 device did not meet the requirements of the British Hypertension Society and, therefore, cannot be recommended for clinical use.

Adult↗

Accuracy of the Dinamap 1846 XT automated blood pressure monitor.

Accurate blood pressure (BP) measurement is important for the detection and treatment of hypertension. Despite widespread use of automated devices, there is limited published evidence for their reliability and accuracy. To determine the reliability and accuracy of the Dinamap 1846XT (Critikon Corporation, Tampa, FL, USA), a commonly used non-invasive oscillometric BP monitor The Dinamap was evaluated against the mercury manometer in 70 randomly selected adult hospitalised medical patients. Each individual underwent three sets of standardised BP measurement by automated method and three sets by mercury manometer by two independent observers. Reliability of BP measurement was assessed by repeated measures analysis. Dinamap accuracy was evaluated according to the American Association of Medical Instrumentation (AAMI) and British Hypertension Society (BHS) guidelines. Most patients were either normotensive or had stage I hypertension. The Dinamap tended to overestimate lower diastolic BP, and displayed poor reliability (P < 0.05). despite meeting aami guidelines, only 59% of systolic and 56% of diastolic dinamap readings were within 5 mm hg of the mercury manometer and 84% of systolic and 80% of diastolic readings were within 10 mm hg (bhs grade c). systolic and diastolic accuracy were worse with pressures >160/90 mm Hg (grade D) although these measures were based on a smaller sample of subjects. In conclusion the Dinamap yields inaccurate estimates of both systolic and diastolic BP even under standardised, and thus optimal conditions. This inaccuracy is exaggerated at higher BP (>160/90 mm Hg), although the number of measurements at higher pressures was small. We recommend that this device not be used when accurate BP measurement is needed for therapeutic decision-making.

Adult↗