Yeast phenylalanyl-tRNA synthetase: evidence for the triggering of an AMP--ATP exchange by tRNA.
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Adenosine Monophosphate↗
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Yeast phenylalanyl--tRNA synthetase. Stimulation of the hydrolysis of enzyme bound aminoacyladenylate upon binding of tRNA.
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Adenosine Monophosphate↗
Irreversible inactivation of arginyl-tRNA ligase by periodate-oxidized tRNA.
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Affinity Labels↗
The 32PPi--ATP isotope-exchange reaction catalyzed by the yeast valyl-tRNA synthetase: order of substrate binding and effect of tRNA.
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Adenosine Triphosphate↗
The aminoacyl-tRNA synthetase-tRNA complex: detection by differential labelling of lysine residues involved in complex formation.
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Amino Acid Sequence↗
Neutron scattering studies of escherichia coli tyrosyl-trna synthetase and of its interaction with trna tyr.
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Amino Acyl-tRNA Synthetases↗
Crystallographic studies on the aspartyl-tRNA synthetase-tRNAAsp system from yeast. The crystalline aminoacyl-tRNA synthetase.
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Amino Acyl-tRNA Synthetases↗
Identification by neutron scattering of tRNA-induced aggregation of Escherichia coli tyrosyl-tRNA synthetase.
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Amino Acyl-tRNA Synthetases↗
N-Alkoxysulfamide, N-hydroxysulfamide, and sulfamate analogues of methionyl and isoleucyl adenylates as inhibitors of methionyl-tRNA and isoleucyl-tRNA synthetases.
A series of sulfamate surrogates of methionyl and isoleucyl adenylate have been investigated as MetRS and IleRS inhibitors by modifications of the sulfamate linker and adenine moieties. The discovery of 2-iodo Ile-NHSO(2)-AMP (58) as a potent Escherichia coli IleRS inhibitor revealed that a significant hydrophobic interaction between the 2-substituent of Ile-NHSO(2)-AMP and the adenine binding site of IleRS provided its high potency to the enzyme.
Binding Sites↗
Catalytic mechanism of phenylalanyl-tRNA synthetase of Escherichia coli K10. Different properties of native and photochemically cross-linked tRNAPhe can be explained in the light of tRNA conformer equilibria.
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Adenosine Monophosphate↗
Valyl-tRNA synthetase form yellow lupin seeds: hydrolysis of the enzyme-bound noncognate aminoacyl adenylate as a possible mechanism of increasing specificity of the aminoacyl-tRNA synthetase.
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Adenosine Triphosphate↗
Establishing the misacylation/deacylation of the tRNA pathway for the editing mechanism of prokaryotic and eukaryotic valyl-tRNA synthetases.
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Amino Acyl-tRNA Synthetases↗
Phenylalanyl-tRNA synthetase induced conformational change of Escherichia coli tRNA phe.
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Amino Acyl-tRNA Synthetases↗
Mechanism of tRNA-aminoacyl-tRNA synthetase recognition: influence of aminoalkyladenylates.
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Adenosine Monophosphate↗
tRNA synthetase paralogs: evolutionary links in the transition from tRNA-dependent amino acid biosynthesis to de novo biosynthesis.
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Amino Acids↗
Specificity of tRNA charging in Tyr-tRNA synthetase.
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Amino Acyl-tRNA Synthetases↗
Correlation between two active forms of valyl-tRNA synthetase and aminoacylation levels of two valine isoaccepting tRNA species in the early stages of sporulation of Bacillus subtilis.
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Amino Acyl-tRNA Synthetases↗
[Separation of the glycine activation and tRNA acylating functions of glycyl-tRNA-synthetase].
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Acylation↗