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Instruction by retinoic acid of incisor morphology in the mouse embryonic mandible.

Endogenous retinoids are present in the embryonic mouse mandible and reach a peak in concentration at the time of the formation of the dental lamina. All-trans retinoic acid is present in a 10-fold higher concentration in the future incisor region of the mouse embryonic mandible at day 11.5. It was found here that exogenous all-trans retinoic acid has pleiotropic effects on the pattern of odontogenesis when applied before the formation of the dental lamina. These effects include a change in the pattern of the dental lamina, supernumerary buds and incisors in the diastema region, and replacement of molars with incisors in the molar region. Thus retinoic acid appears to instruct incisor morphology in the mouse embryonic mandible.

Animals↗

Maxillary midline diastema: a case report involving a combined orthodontic/maxillofacial approach.

This paper presents an orthodontic case of a large (14.5 mm) maxillary midline diastema that was related to the presence, and subsequent removal of 2 median maxillary supernumerary teeth and resulting bone loss. A combined orthodontic and maxillofacial approach involving bone grafting and fixed appliances was used to close the space. This episode of care was organized as interceptive treatment during development of the permanent dentition.

Child↗

Aggressive periodontitis with supernumerary teeth: a retrospective study.

BACKGROUND: There are four key studies in the periodontology literature reporting the correlation between supernumerary teeth and aggressive periodontitis. The aim of this study is to detect such a relationship. METHODS: Patients with supernumerary teeth were identified retrospectively from their orthopantomographs and were invited to the periodontology department for intraoral examination. They were then evaluated for aggressive periodontitis. The number of existing teeth, age, family histories, attachment loss, probing depths, and bleeding on probing scores were recorded. RESULTS: Of the 5,850 subjects randomly observed among 48,000 patients, only 174 exhibited supernumerary teeth. Of these 174 subjects, only three patients were diagnosed with aggressive periodontitis. One of the patients was also suffering from Fanconi's anemia. CONCLUSIONS: Despite the similarities (aggressive periodontitis accompanied by supernumerary teeth) in the previous reports, we do not agree with the earlier results. We rather suggest that this association might be a random occurrence, rather than a biological one, although this observation should be further investigated using genetic testing.

Adult↗

[Numerical anomaly of teeth in mongrel juvenile dogs. Canis familiaris].

As this study subjects, upper and lower dentitions of 49 mongrel dogs were used. X-ray films of the upper and lower dentitions of the dogs were taken. These films were from the collection of the Department of Pedodontics, School of Dentistry, Aichi-Gakuin University. Although the data on the sex and age of the dogs were not available, the dental ages were judged to range from the deciduous dentition to the early mixed dentition. Molars were not dealt with in this study for two reasons: 1) the molars of many of the subjects had not yet been calcified, and 2) the upper second and/or lower third molars, if present, had frequently been sacrificed when the jaws were separated. Numerical anomalies were observed in 16 dogs (32.7%). And infranumerary teeth were observed in 14 dogs (26.8%). Incidences of infranumerary teeth were higher in the secondary dentitions than in the primary ones. Most of the infranumerary teeth were found in both the upper and lower premolars, but not in the upper incisors and the upper and lower canines. Infranumerary teeth often occurred symmetrically whereas supernumerary teeth occurred asymmetrically. This investigation suggests that tendency of the reduction of the upper third premolar was considered to be caused by the reduction of the maxilla through the process of domestication. These results are inconsistent with Fujita's terminal reduction theory.

Animals↗

Retrospective survey of dental anomalies and pathology detected on maxillary occlusal radiographs in children between 3 and 5 years of age.

PURPOSE: Radiographs play an important role in the diagnosis of anomalies and pathology of the oral structures of young children as well as in the interception and management of developmental problems in the dentition. The occlusal film, commonly indicated in the young child, is a helpful tool in establishing a baseline and in revealing certain region-specific dental concerns in a timely fashion. The purpose of this retrospective study was to perform a comprehensive examination of maxillary occlusal radiographs in a clinical pediatric population and to determine the prevalence of dental anomalies and pathology in the premaxilla in children between 3 and 5 years of age. METHODS: Radiographs of healthy preschool children (236 males and 264 females), who received their initial examination at the University of Texas-Houston Pediatric Dentistry Graduate Clinic during 1997 and 1998, were reviewed independently by two pediatric dentists, using a 2X magnifying lens and a standard dental light box. Interexaminer discrepancies were resolved by consultation and mutual agreement. RESULTS: Ninety-two (18%) showed no evidence of dental caries, restorations, current pathological conditions, or other anomalies. Frequencies of anomalies such as congenitally missing and supernumerary teeth were consistent with other reports. CONCLUSIONS: These observations emphasize the importance of obtaining intraoral radiographs on preschool children who are in apparent good dental health.

Anodontia↗

Study on supernumerary teeth in the maxillary anterior area in children. 1. Clinical analysis.

This is a study of supernumerary teeth in the maxillary anterior area in children. More than 60,000 child patients were examined. The 842 supernumerary teeth in the maxillary anterior area, found in a total of 682 children, were analyzed clinically. The incidence of supernumerary teeth was 1.12%. The male-female ratio was 3 to 1. Supernumerary teeth found were single and multiple types, with a ratio of 3 to 1. The eruption direction was normal (51.2%), inverted (36.2%) or horizontal (7.6%). Approximately 65% were found impacted in the maxilla.

Adolescent↗

Orthodontic treatment of a patient with multiple supernumerary teeth and mental retardation.

Supernumerary teeth may lead to impaction or ectopic eruption of maxillary incisors, crowding, oronasal fistula, follicular cyst, migration of adjacent teeth and root resorption. In this presentation, an 11-year-old male patient with 4 supernumerary teeth in the maxillary anterior region and a slight mental retardation problem will be presented. After extraction of the supernumerary teeth, the large space created by distal migration of central incisors was closed by orthodontic treatment. Although initial patient compliance was weak and caused difficulties in the course of treatment, orthodontic treatment was completed successfully.

Cephalometry↗

[Dentomaxillary and -facial problems in cleidocranial dysplasia].

A 14-year old boy with cleidocranial dysplasia was referred because of an almost complete presence of the deciduous dentition. Diagnostics by means of a panoramic radiograph, lateral headfilm, CT scan and 3D computer images of the dentomaxillary complex showed 7 supernumerary permanent teeth: 13', 11', 21', 23', 28', 35' and 45'. A combined orthodontic-surgical treatment was started. The supernumary teeth were removed surgically and the impacted teeth are exposed. The closed eruption technique was used to extrude these teeth orthodontically.

Adolescent↗

Dentigerous cysts associated with supernumerary teeth.

Dentigerous cysts associated with supernumerary teeth are rare and estimated to constitute 5-6% of all dentigerous cysts. They resemble the usual dentigerous cysts in terms of sex predilection and age distribution. The vast majority, about 90%, are associated with a maxillary mesiodens. The literature is reviewed and 6 additional cases reported.

Adult↗

Multiple and relapsing supernumerary teeth associated to dens invaginatus. Review of the literature and case report.

The aim of this paper is to show problems related to supernumerary teeth therapy according to their formation and mineralization. The clinical case of an 11-year old boy suffering from alteration of the eruptive sequence of the upper incisor teeth caused by 2 supernumerary teeth in the premaxilla, is reported. What is interesting about this case is that after the surgical removal of the supernumerary teeth, with a radiographic examination taken 6 months later, 2 other supernumerary teeth were observed. The authors point out that while the clinical approach can be the same for different situations it is not possible to have the same approach for the surgical therapy which may be different from case to case.

Child↗

Chondroectodermal dysplasia (Ellis-van Creveld syndrome): report of two cases.

Our two patients with chondroectodermal dysplasia had most of the classic manifestations of the syndrome. The simultaneous occurrence of partial anodontia and embedded supernumerary and second premolars in the mandible in one patient was interesting. The inverted impaction of the left maxillary lateral incisor is also a unique finding. The median fissure on the tongue may be an associated developmental anomaly of the syndrome.

Adolescent↗

Dental abnormalities in permanent dentition in children with submucous cleft palate.

Seventy-three children with submucous cleft palate (38 girls and 35 boys), mean age 8.2 years (range 7.7-9.5), were studied retrospectively from orthopantomograms. Dental abnormalities in permanent dentition were found in 26 patients (36%). Missing teeth, mainly lower 2nd premolars, upper lateral incisors, and upper 2nd premolars, were found in 12 patients (16%). Most of the patients had 1 or 2 missing teeth, 2 had 3 missing teeth. In 5 patients hypodontia was associated with another dental abnormality. Other dental abnormalities included peg-shaped lateral incisors in 7 patients (10%), ectopic eruption of upper 1st molars in 6 patients (8%), transposition of upper canines and 1st premolars in 3 patients (4%), supernumerary teeth in 2 patients (3%), and palatally displaced upper canines in 1 patient (1%). As children with submucous cleft palate have a tendency towards increased frequency of missing teeth and other dental abnormalities, the need for thorough clinical and radiological dental examination is emphasized.

Anodontia↗

Orthodontics. Part 10: Impacted teeth.

This section deals with the important issue of impacted teeth. Impacted canines in Class I uncrowded cases can be improved by removal of the deciduous canines. There is some evidence that this is true for both buccal and palatal impactions. Treatment of impacted canines is lengthy and potentially hazardous. Interceptive measures are effective and preferred to active treatment. Supernumerary teeth may also cause impaction of permanent incisors, their early diagnosis and appropriate treatment is essential to optimise final outcomes. If there are any doubts about impacted teeth it is better to refer too early than too late, this latter option may unnecessarily extend the length of treatment as well as the treatment required.

Bicuspid↗

Severe dental aberrations in familial steroid dehydrogenase deficiency: a new association.

Severe numerical dental aberrations are rare, and are most often seen as a part of certain syndromes. We here report on a Saudi Arabian family where first-cousin marriages have caused numerical and structural dental abnormalities linked to autosomal recessively inherited liver diseases. The two latest affected children in this family have had their liver defect successfully treated with fat-soluble vitamins and chenodeoxycholic acid, enabling us to study their dental development. One boy exhibits 11 supernumerary teeth, a general hypomineralisation and enamel hypoplasia, while an affected cousin successfully diagnosed at an early age, so far, only suffers from structural enamel defects. The children are otherwise healthy. There is no resemblance to any known syndromes. We suggest that the supernumerary teeth and the liver disease are caused by the same genetic defect, and represent a new association. The hypomineralisation, however, is most likely to result from vitamin deficiency secondary to malabsorption during the first years of life, before successful treatment was instituted.

3-Hydroxysteroid Dehydrogenases↗

Anterior maxillary supernumerary teeth: a clinical and radiographic study.

Clinical records and radiographs of 90 patients with 113 anterior maxillary supernumerary teeth (mesiodens) have been evaluated. Although uncommon, mesiodentes are the most frequent supernumerary teeth and may disturb the eruption and/or position of the adjacent permanent incisors. Clinical and radiographic examination may disclose the number, direction and location of mesiodentes and their effects on neighbouring teeth. In the present study the majority of the supernumerary teeth lay palatal to the central incisors. Complete or partial eruption of a mesiodens was rare, hence the importance of radiographs to locate supernumerary teeth in the premaxilla. Pathological findings included the formation of dentigerous cysts in three patients and complete ossification of the pericoronal space with resorption of the crown of the mesiodentes in eight cases. Retention and malposition of the adjacent permanent incisors occurred in 39 and 24 cases, respectively.

Adult↗

A natural history of cleidocranial dysplasia.

Cleidocranial dysplasia (CCD) is an autosomal dominant skeletal dysplasia associated with clavicle hypoplasia and dental abnormalities. The condition is caused by mutations in the CBFA1 gene, a transcription factor that activates osteoblast differentiation. Clinical characteristics associated with CCD have previously been described in case reports and small case series. This study was undertaken to gain a more complete delineation of clinical complications associated with CCD. The study population was composed of 90 CCD individuals and 56 relative controls ascertained from genetic and dental practices in the United States, Canada, Europe, and Australia. A number of previously unrecognized complications were significantly increased including: genua valga, scoliosis, pes planus, sinus infections, upper respiratory complications, recurrent otitis media, and hearing loss. Primary Cesarean section rate was significantly increased compared to relative controls and the general population rate. Finally, dental abnormalities, including supernumerary teeth, failure of exfoliation of the primary dentition, and malocclusion, are serious and complex problems that require intervention. Clinical recommendations based on the results of this study are included.

Adolescent↗

Supernumerary molars. A review of 53 cases.

Supernumerary molars are not uncommon and may be found nearly anywhere in the dental alveolar arches. A series of 36 patients that presented with 53 supernumerary molars are reviewed. They occurred more frequently in the maxilla (86.8%), had little or no clinical significance, tended to be impacted, and were not associated with the impactation of the third molar. Four cases of maxillary fifth molars are described.

Adolescent↗

Sequential development of multiple supernumerary teeth in the mandibular premolar region -- a radiographic case report.

This report presents a case of multiple supernumerary teeth developing in the mandibular premolar region in an Asian female patient. A series of radiographs taken over a 10-year period, demonstrate the sequential development of these teeth during the patient's early and middle teenage years. The importance of regular radiographic review and appropriate management for such cases is discussed.

Adolescent↗