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[Differences in the reaction of the mucosa of the gastric fundus and pylorus to high concentration of ethanol].

Histopathological morphometric analysis were made to determine the degree and extent of the stomach mucosa lesions in fundus and antrum of 36 rats after 15 min., 1, 24 and 96 hours after ethanol insult. At the early stage the intensity of the lesion caused by direct influence of ethanol was in both parts similar. Evident differences occurred after 1 hour, and especially after 24 hours, and were caused by secondary, endogenous agents. Among them the most important seems to be the specificity of the vascular net reaction to alcohol stimulus in each part of the stomach, differences in secretion intensity and composition of the superficial mucosal gel, as well as in the contents of some active substances.

Animals↗

[Involvement of the urinary tract in a syndrome of congenital epidermolysis bullosa and atresia of the pylorus].

Epidermolysis bullosa associated with pyloric atresia is a rare autosomal recessive condition, usually fatal in the first few months of life. Since 1983 urinary tract disease is known to be another manifestation of this syndrome which becomes the main problem in children surviving beyond infancy. The case of a 2 1/2 year-old boy with mild cutaneous manifestations of junctional epidermolysis bullosa, corrected pyloric atresia and renal disease is reported. Hematuria, dysuria, obstruction of the uretero-vesical junction and worsening hydronephrosis led to bilateral ureterostomy (ureteral reimplantation was not attempted because the thickness of the bladder wall and the extensive ureteral fibrosis).

Child, Preschool↗