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Brain architecture management system.

The nervous system can be viewed as a biological computer whose genetically determined macrocircuitry has two basic classes of parts: gray matter regions interconnected by fiber pathways. We describe here the basic features of an online knowledge management system for storing and inferring relationships between data about the structural organization of nervous system circuitry. It is called the Brain architecture management system (BAMS; http://brancusi.usc.edu/bkms) and it stores and analyzes data specifically concerned with nomenclature and its hierarchical taxonomy, with axonal connections between regions, and with the neuronal cell types that form regions and fiber pathways.

Animals↗

Diversity, equal access and information.

The overall aim of diversity is to ensure that every individual, whatever their differences, has fair and equitable access to health care and to employment based on clinical need and merit. This has advantages for staff by allowing them to give of their best and for patients by better identifying and meeting their needs. Evidence shows that individuals from minority groups are often not treated fairly and positive action is required to redress the balance.

Appointments and Schedules↗

Detection of adverse drug reactions in a neurological department: comparison between intensified surveillance and a computer-assisted approach.

OBJECTIVES: Adverse drug reactions (ADRs) leading to hospitalisation or occurring during hospital stay contribute significantly to patient morbidity and mortality as well as representing an additional cost for healthcare systems. The aim of this study was to provide data about the type and incidence of ADRs in a neurological department and to compare two different methodological approaches to collecting information on ADRs. METHODS: The two methods used were intensified surveillance of neurological wards by daily ward rounds and computer-assisted screening for ADRs by means of pathological laboratory parameters. RESULTS: Of admissions to the neurological department, 2.7% were caused by an ADR and 18.7% of patients experienced at least one ADR during hospitalisation. The positive predictive values of pathological laboratory parameters ranged between 0% (eosinophil count) and 100% for increased drug serum concentrations and international normalised ratio, i.e. the latter were always accompanied by a clinically relevant ADR. However, only half of all ADR could be detected by pathological laboratory parameters, the sensitivity of this method came to 45.1% with a specificity of 78.9%. CONCLUSION: Similar to departments of internal medicine, a high number of ADRs occur on neurological wards. The predominant ADRs were those typical of neurotropic medications such as dyskinesia and increased sedation. Due to the age of the patients involved, cardiovascular co-medication is often prescribed and represents an additional risk factor for ADRs. By measuring pathological laboratory parameters the majority of ADRs could not be detected in neurological patients.

Adverse Drug Reaction Reporting Systems↗

Directions for the International Society for Research on Internet Interventions (ISRII).

In 2004, the International Society for Research on Internet Interventions (ISRII) was formed to encourage eHealth researchers to collaborate in their efforts to further the science behind developing, testing, and disseminating Web-based treatment programs. The group held its second meeting (April 2006) to clarify the Society's direction and identify key issues that need addressing in the field. These issues are identified and examined in the current paper. Given the success of using the Internet to treat a range of medical and mental health problems, and the growing need for better dissemination of health care, Internet interventions will almost certainly play a prominent role in global health. ISRII plans to provide the necessary venue to ensure the science driving this field is strong, enabling researchers to conduct the highest quality research and permitting meaningful conclusions from completed studies.

Behavior Therapy↗

RADCOM: a computerized translation device for use during fluoroscopic examination of non-English-speaking patients.

We developed and have implemented RADCOM (RADiology COMmunicator), a computerized speech-based language translator for use during fluoroscopic examination of non-English-speaking patients. It is controlled completely by voice commands issued into a headset microphone. The system output is digital audio via a small speaker, in the native language of the patient. RADCOM currently supports more than 40 commands in more than a dozen languages. The language data base is easily expandable. We have performed more than 20 fluoroscopic examinations with the RADCOM system. The non-English-speaking patients respond well, following the selected instructions appropriately.

Communication Barriers↗

Preparing data for analysis using microsoft Excel.

A critical component essential to good research is the accurate and efficient collection and preparation of data for analysis. Most medical researchers have little or no training in data management, often causing not only excessive time spent cleaning data but also a risk that the data set contains collection or recording errors. The implementation of simple guidelines based on techniques used by professional data management teams will save researchers time and money and result in a data set better suited to answer research questions. Because Microsoft Excel is often used by researchers to collect data, specific techniques that can be implemented in Excel are presented.

Biomedical Research↗

Information needs and information seeking behaviour in primary health care.

A questionnaire survey of 186 general practitioners in Sweden showed that 67% saw the overall supply of medical information as less satisfactory or unsatisfactory, and that 80% experienced major hindrances in seeking relevant information. The most frequent need for information concerned general medicine, with respect to both diagnosis and choice of therapy. Of situations which required additional information, only every second was completely resolved. These results imply a need for a reorganization of the supply of information to general practitioners. As they cannot depend on conventional medical libraries for day-to-day information, personal libraries should be improved and updated regularly, and be readily to hand. Computer technology should be considered for communication between health care providers, and as support for differential diagnosis in general medicine.

Consumer Behavior↗

Use of a constraint satisfaction network model for the evaluation of the methadone treatments of drug addicts.

Constraint Satisfaction Networks were used by Semeion, a Research Center of Science of Communication, in order to analyze drug-addict patient data files, provided by the Jerusalem Methadone Treatment Center. The short and partial analysis carried out in this article is presented to show how this high technology can be a support for treatment staff in order to improve the quality and the timeliness of the necessary intervention with patients. One of the problems for which the networks could offer support is, for example, the individuation or "matching" of the most suitable therapy for the patient during the treatment planning phase. In this field the networks need to analyze data files of patients in therapy at different centers, with the results collected after many years of observation. What follows, obviously, only has demonstrative values.

Adult↗

Assessment of health information technology: which questions for which systems? Proposal for a taxonomy.

After a brief description of the main domains of application of medical informatics, a typology of questions to be assessed, and of the involved actors, is presented. Dimensions of technology assessment include techniques, medical and health efficacy, economics, sociology, and law and ethics. Barriers to evaluation are analysed. They include barriers related to the domain complexity, human motivation and methodological barriers. Finally categories of solutions and research areas are suggested.

Classification↗

Health-care quality promotion through infection prevention: beyond 2000.

Health-care value purchasing, complex health-care systems, and information technology are the three most important change drivers influencing the interrelated themes of the 4th decennial conference: accountability, quality promotion through infection prevention across the health-care delivery system, and medical informatics. Among the change drivers influencing themes of future conferences may be a societal mandate for health promotion and health-care access for all.

Delivery of Health Care↗