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PubMed2006

Behavioural problems in 2-year-olds: links with individual differences in theory of mind, executive function and harsh parenting.

BACKGROUND: Cognitive and family factors are implicated in the origins of behavioural problems, but little is known about their independence or interplay. METHODS: We present data from 127 two-year-olds from predominantly disadvantaged families who completed tests of 'theory of mind' (ToM), executive function (EF) and verbal ability. Researchers' home-visit ratings and detailed video-based coding of mother-child interactions were combined to give an aggregate measure of harsh parenting, while behavioural problems were indexed by a multi-informant, multi-setting, multi-measure aggregate. RESULTS: Harsh parenting and deficits in ToM and verbal ability each predicted unique variance in behavioural problems; independent effects of EF were only marginally significant. Harsh parenting and ToM interacted significantly in their effects on behavioural problems. CONCLUSIONS: Child and family influences on behavioural problems should be considered in tandem, as they show significant interplay; in particular, advanced ToM skills appear to buffer young children against effects of harsh parenting.

Child, Preschool↗
PubMed1976

Opening windows into a child's mind.

Children may not know, or cannot tell, what is causing their psychosomatic symptoms. Methods are outlined which may help paediatricians to see what goes on in children's minds and also help children to express it. For some children, such expression may itself be healing: for others, further help will be needed. Interested paediatricians will learn to distinguish between these groups.

Adolescent↗
PubMed1992

Is it important that the mind is in a body? Inhibition and the heart.

The hypothesis is advanced that certain inhibitory processes necessarily involve autonomic adjustments. Such adjustments would represent a constraint on information processing imposed by the location of the mind in a body. Evidence is reviewed showing that motoric inhibition is related to a transient delay in heartbeat generation. The delay is shown to further depend upon when inhibition occurs in the cardiac cycle. It is argued that this form of interaction between central and autonomic nervous system processing may be common. Central nervous system processes that may control inhibition and integrate information processing with motoric and autonomic processes are discussed.

Autonomic Nervous System↗
PubMed1976

Elderly applicants to long-term care institutions. I. Their characteristics, health problems and state of mind.

As part of a study of long-term institutional care of the elderly, this report presents a comparison of the characteristics, health problems, and state of mind of 193 elderly applicants for such care (Group A) with those of 141 elderly persons living independently in the community (Group I). Group A members were older, living with a spouse less often, and had low incomes. They showed much more cerebrovascular disease, incontinence, recent loss of independence in the activities of daily living, dementia, recent hospitalization, loneliness, and depression. They had had much less recent involvement in social and recreational activities, although most had not been socially isolated. They had received more extensive help from relatives and friends, and it seemed unlikely that additional help from these sources would keep many more of these elderly persons out of institutions. Community agencies and services had been used by a relatively low proportion of Group A, and hardly at all by Group I.

Activities of Daily Living↗
PubMed1990

Mind-body problems in family therapy: contrasting first- and second-order cybernetics approaches.

Using detailed case examples, we contrast first- and second-order cybernetics approaches to family problems involving somatic symptoms in a family member. A second-order cybernetics approach views the reality of the problem as linguistically shaped by those interacting around it, including the therapist and observing team members. This co-constructed reality, the story of the problem, inadvertently contributes to the problem's endurance by narrowing the choice of more effective solutions. In our approach, the therapist elicits from each person his or her story about the illness in the family. The therapist then facilitates a therapeutic conversation that provides a context for new linguistic distinctions to be drawn, including the way mind and body may interact to generate the symptoms. Shifts in beliefs and behaviors follow, and more innovative solutions to the problem can then emerge. Unlike the approach in our previously published work based upon ecosystemic patterns as "system diagnoses," this approach uses only descriptions and explanations of the problem as are collaboratively constructed within this therapeutic conversation.

Adult↗
PubMed2000

A chromosomal locus encoding a phosphoserine phosphatase- and a truncated MinD-like protein affects differentiation in Streptomyces azureus ATCC14921.

We isolated BalA1, a representative transformant of thiostrepton-producing strain Streptomyces azureus ATCC14921, which carries an approximately 2.5-kb chromosomal DNA fragment on a high-copy-number plasmid. While strain BalA1 formed little aerial hyphae, its morphological defect was restored by cultivation with S. azureus, S. laurentii, etc. Strain BalA1 strongly inhibited the growth of Bacillus subtilis more than its parent strain, and also inhibited the development of its parent and some Streptomyces strains with thiostrepton resistance. Furthermore, it induced Streptomyces coelicolor A3(2) to produce undecylprodigiosin, at an early stage of growth. The 2.5-kb fragment contained two orfs, orf1 and truncated orf2. The deduced products were somewhat similar to phosphoserine phosphatase-like protein and the N-terminal region of MinD-like protein, respectively. The individual function of orf1 or the function of both orf1 and truncated orf2 seems to induce particular phenotypes or properties in strain BalA1.

Adenosine Triphosphatases↗
PubMed2004

No evidence for impaired 'theory of mind' in unaffected first-degree relatives of schizophrenia patients.

OBJECTIVE: The aim of this study was to investigate the possibility that 'theory of mind' (ToM) impairments are associated with schizophrenia liability. METHOD: Forty healthy control subjects and 79 first-degree biological relatives of schizophrenia patients (32 siblings and 47 parents) received the Eyes Test, during which subjects are asked to choose the word best describes the mental state of a person whose eyes are depicted on a photograph. RESULTS: The affected relatives (n = 14) performed worse on the Eyes Test compared with the controls (P = 0.0001), whereas the unaffected relatives (n = 65) showed intact performances (P = 0.4). The Eyes Test values did not correlate with age and IQ. There was no significant difference between male and female participants. CONCLUSION: ToM deficits, as measured by the Eyes Test, are not associated with schizophrenia liability.

Adult↗
PubMed2005

Evidence for theory of mind deficits in euthymic patients with bipolar disorder.

OBJECTIVE: i) To investigate the subtle ToM (theory of mind) deficits in euthymic patients with bipolar disorder. ii) To investigate the impact of non-ToM cognitive deficits on ToM abilities. METHOD: Forty-three euthymic patients with bipolar disorder and 30 healthy control subjects were involved in this study. ToM was assessed by the Eyes test and the Hinting task. Both groups were also evaluated with a comprehensive neuropsychological battery including tasks for basic emotion and face recognition. RESULTS: The patient group was impaired on both of the ToM tasks. The patient group also showed impairment in many cognitive tasks including tasks related to sustained attention. CONCLUSION: Even euthymic patients with bipolar disorder may be impaired in advanced ToM tasks. Executive dysfunction and some other cognitives deficits such as basic emotion recognition may be at least partly responsible for this result.

Adult↗
PubMed2001

Suicide: what is in the clinician's mind?

The assessment and treatment of the suicidal patient challenge all clinicians, regardless of training or theoretical orientation, to draw upon their knowledge and judgment to formulate the best treatment plan possible. As great as the influence of demographics, genetics, and psychobiology are, what is in the mind of the clinician, whether it is anxiety, confidence, knowledge, or uncertainty, will determine the fate of the suicidal patient.

Countertransference↗
PubMed1993

You in Mind: a preventive mental health television series.

This study of BBC Television's 'You in Mind' series provides preliminary evidence for the benefits of a mass media approach to preventive mental health. The series was seen by a large national audience who appraised it positively. It had a greater impact in the area of understanding problems as opposed to seeing what to do about them, and a greater impact on the viewer's perceptions of the problems of people the viewers knew, as opposed to the problems of the viewers themselves. Measures of intentions to change behaviour, even when corrected for over-reporting, suggest that a significant minority of the audience had changed or intended to change their behaviour as a result of the series. However, no specific pre-post changes in coping or help-seeking were found. These findings are discussed in terms of the potential and limitations of the mass media for mental health promotion.

Adolescent↗
PubMed1997

Linking mind and brain in the study of mental illnesses: a project for a scientific psychopathology.

Brain research on mental illnesses has made substantial advances in recent years, supported by conceptual and technological developments in cognitive neuroscience. Brain-based cognitive models of illnesses such as schizophrenia and depression have been tested with a variety of techniques, including the lesion method, tract tracing, neuroimaging, animal modeling, single-cell recording, electrophysiology, neuropsychology, and experimental cognitive psychology. A relatively sophisticated picture is emerging that conceptualizes mental illnesses as disorders of mind arising in the brain. Convergent data using multiple neuroscience techniques indicate that the neural mechanisms of mental illnesses can be understood as dysfunctions in specific neural circuits and that their functions and dysfunctions can be influenced or altered by a variety of cognitive and pharmacological factors.

Affect↗
PubMed2000

Neuroscience: breaking down scientific barriers to the study of brain and mind.

In this month's essay, Eric R. Kandel and Larry R. Squire chronicle how brain research has migrated from the peripheries of biology and psychology to assume a central position within those disciplines. The multidiscipline of neuroscience that emerged from this process now ranges from genes to cognition, from molecules to minds.

Animals↗
PubMed1973

Thoughts in mind of a person with cancer.

The paper is based on the personal experience of many patients suffering from cancer. It analyses in a discursive way thoughts which may be present in the minds of cancer patients. The paper also briefly discusses the techniques used to minimize the common fears of the cancer patient.

Attitude of Health Personnel↗
PubMed2000

Capturing prescribers' minds.

The prescription plays a key role in the provision of healthcare, culminating many consultations, affecting patient well-being and committing expenditure of around 13% of the NHS budget. Ultimately, the contents of the prescription depend on the prescriber's knowledge, attitudes and beliefs, and there are many who would wish to influence these. The eighth annual Drug and Therapeutics Bulletin symposium, 'Capturing prescribers' minds', looked at ways of influencing prescriber's decisions. Here, we summarise the key points raised in the presentations and in subsequent discussion.

Attitude of Health Personnel↗
PubMed2006

Animal rights, animal minds, and human mindreading.

Do non-human animals have rights? The answer to this question depends on whether animals have morally relevant mental properties. Mindreading is the human activity of ascribing mental states to other organisms. Current knowledge about the evolution and cognitive structure of mindreading indicates that human ascriptions of mental states to non-human animals are very inaccurate. The accuracy of human mindreading can be improved with the help of scientific studies of animal minds. However, the scientific studies do not by themselves solve the problem of how to map psychological similarities (and differences) between humans and animals onto a distinction between morally relevant and morally irrelevant mental properties. The current limitations of human mindreading-whether scientifically aided or not-have practical consequences for the rational justification of claims about which rights (if any) non-human animals should be accorded.

Adult↗
PubMed1994

Living wills: would sick people change their minds?

Patients admitted acutely to a geriatric medical unit were interviewed on admission about their opinions on cardiopulmonary resuscitation (CPR). They underwent a general examination and their mental health was documented by completing the geriatric depression scale. Those who did not wish CPR in the event of a cardiac arrest were questioned again on recovery. Of 216 patients admitted, only three objected to answering the questions and after the other exclusion criteria were applied, 100 patients were included in the study. A total of 92% of patients wished CPR in the event of a cardiac arrest. The 8% who did not wish CPR contained more people scoring high on the geriatric depression scale. After recovery, three of that eight had changed their minds and wished CPR if required. Patients who are acutely unwell may make decisions that are influenced by their condition at this point in time and it is important to recognize that these decisions may not be maintained. In this study, consultant geriatricians did not reflect their patients' desires in making decisions about who should receive CPR if required.

Acute Disease↗
PubMedDate not supplied

Can verbalization remedy the theory of mind deficit in schizophrenia?

Several studies provide convincing evidence of a specific deficit in the theory of mind (ToM) in some patients with schizophrenia. This ToM deficit consists of an inability to attribute relevant mental states to others, and studies suggest it has to be regarded as functional and remediable through the use of reinforced context processing. To investigate this, the present study compares the performances of 25 schizophrenics and 25 matched controls in a task exploring ToM before and after the introduction of verbal material into the task, initially conceived as nonverbal. All the controls and half of the schizophrenic subjects who did not initially perform at the best level remediated with verbalization, while 9 of the schizophrenics exhibited no remediation. These poor performers are characterized by a longer duration of illness. The cognitive plasticity and the characteristics of patients who do/do not remediate are discussed in the light of findings obtained with the Wisconsin Card Sorting Test. The clinical implication of these results is important since they suggest that some patients would benefit from cognitive rehabilitation in terms of their ability to attribute relevant mental states to others.

Adult↗
PubMed2005

Mindfulness-based stress reduction as an adjunct to outpatient psychotherapy.

BACKGROUND: Research on Mindfulness-Based Stress Reduction (MBSR) has supported the utility of the technique in a number of clinical settings. This study explored whether MBSR, used as an adjunct to individual psychotherapy, would result in more rapid alleviation of symptoms, increased achievement of therapeutic goals, and a decrease in number of therapy sessions sought by clients. METHODS: A group undergoing psychotherapy coupled with training in MBSR was compared with a group undergoing psychotherapy alone. RESULTS: At the conclusion of MBSR training, the groups showed a comparable significant decrease in psychological distress. However, the MBSR group's gains on a novel measure of goal achievement were significantly greater than those of the comparison group. In addition, the MBSR group terminated therapy at a significantly greater rate than the comparison group. CONCLUSION: The effects of introducing MBSR early in psychotherapy, as well as its effect on self-directed goal attainment in non-psychotherapy contexts, deserve further attention.

Adult↗