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An eighteenth century view of the placebo effect (Rétif de la Bretonne).

Placebo - the promise to please the Lord of medieval prayer became the "pious fraud" (Thomas Jefferson) of late 18th century medical practice. Quoted here is Rétif de la Bretonne (1734-1806), one of the most prolific novelists and popular encyclopedists ever, also highly regarded by some illustrious critics, as he is giving his cynical views about the "prejudices", (rather then "placebos") in religion, politics, and the art of healing.

France↗

Bromide psychosis: a literary case.

Author Evelyn Waugh, noted for such works as Brideshead Revisited, published in 1957 an autobiographical account of his own bromide psychosis in the novel The Ordeal Of Gilbert Pinfold. Until now, however, the fact of his bromide poisoning had gone unrecognized both in biographies of Waugh and in analyses of the novel. Ordeal gives a detailed, accurate, day-by-day description of bromide psychosis. This unusual, witty, and fascinating piece of literature actually provides the most complete monograph on the subject. In this article we review the literature on bromide poisoning, discuss the events of the novel and of Waugh's life in light of his bromide psychosis, and suggest the relevance of the case to medicine.

Bromides↗