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PubMed1994

Achalasia associated with esophageal diverticula. Prevalence and potential implications.

Although esophageal diverticula have been rarely reported in patients with achalasia, their prevalence and the potential implications of the relationship are not well known. We reviewed the medical records and the manometric and radiographic examinations in 120 patients with achalasia to determine the prevalence of esophageal diverticula and to evaluate their importance in this motility disorder. Esophageal diverticula were found in only 6 (5%) of 120 patients, and all were located in the lower half of the esophagus. Sex distribution and the prevalence of dysphagia and regurgitation, which affected all patients with diverticula and 88% of those with achalasia only, were not different significantly. Patients with esophageal diverticula were significantly older (72 vs. 52 years) than those without diverticula. In 5 of 6 patients with diverticula, mean lower esophageal sphincter (LES) pressure was 44.5 mm Hg compared to 39.1 mm Hg in 86 of 114 patients with achalasia only. Treatment by pneumatic dilatation was done in 4 patients with esophageal diverticula and in 105 patients without diverticula. Five esophageal perforations occurred, all in patients without esophageal diverticula.

Adolescent↗
PubMed2005

Suspected pharyngoesophageal perforation after a difficult intubation: a case report.

Although uncommon and rarely reported, pharyngoesophageal perforation has medical and legal consequences of substantial proportion. Perforation of the upper aerodigestive system may result in severe airway complications that include pneumothorax, pneumonia, mediastinitis, and retropharyngeal abscess. Despite the relative rare occurrence of esophageal perforation during intubation, this type of injury is associated with the poorest outcome, especially when the diagnosis and treatment are delayed. Our case report presents a healthy 23-year-old female for a thyroidectomy. Postoperatively she developed what appeared to be symptoms of pharyngoesophageal injury, suspected to be related to blunt trauma from laryngoscopy. Knowledge of and prompt attention to the cardinal signs of pharyngoesophageal injury in partnership between the anesthetist and the surgical team were the key instruments in ruling out this potentially devastating diagnosis.

Adult↗
PubMed1976

A combined surgical approach in the management of achalasia of the esophagus.

The treatment of achalasia at the present time is far from being ideal. The results of pneumatic dilatation have not always been impressive and the risk of esophageal perforation is real. Modified Heller operation has succeded in relieving obstructive symptoms in the majority of patients with achalasia. However, the reported incidence of reflux esophagitis following Heller myotomy is four to 37 per cent. In 25 patients with achalasia followed up to 10 years after Heller myotomy, nine patients had symptomatic reflux and three patients developed esophageal strictures. We believe the addition of an anti-reflux operation should be considered in all patients undergoing operation for achalasia and especially those patients with preoperative symptoms of reflux.

Dilatation↗
PubMed2003

Delayed esophageal injury without instrumentation failure: complication of anterior cervical instrumentation.

The authors describe a case of a 67-year-old man who presented with a delayed esophageal perforation 4 years after anterior cervical spine surgery for spondylotic myelopathy. Diagnosis was made with esophagoscopic visualization of the lesion and repair performed with hardware removal and esophageal closure utilizing a sternocleidomastoid muscle flap. The pertinent literature is reviewed and the therapeutic implications discussed.

Aged↗
PubMed2005

Boerhaave's syndrome: diagnosis and treatment.

Boerhaave's syndrome, or postemetic rupture of the esophagus,represents one of several etiologies of esophageal perforation. Early diagnosis, which requires both a high index of suspicion and contrast esophagography, is essential for optimal outcome. Primary repair is often possible, although other techniques, such as esophageal exclusion or diversion, may be appropriate in certain circumstances.

Esophageal Perforation↗
PubMedDate not supplied

Sepsis syndrome induced by tuberculous perforation of the esophagus.

Perforation of the esophagus induced by tuberculosis with no evidence of HIV infection is an extremely unusual presentation of the disease. We report on a 41-year-old man presenting with an esophageal perforation who developed a sepsis syndrome characterized by multiple organ dysfunction. The perforation was covered endoscopically with a tube, the patient recovered from cardiovascular, renal and pulmonary dysfunction under intensive care treatment, including antimycobacterial therapy. In response to endoscopic and medical treatment the size of the lesion decreased and disappeared 56 days after diagnosis. The patient could be discharged 2 months after admission and remained asymptomatic after a 12 month follow-up examination.

Adult↗
PubMed1997

Surgical laparoscopy with intraoperative manometry in the treatment of esophageal achalasia.

The aim of this study was to describe and evaluate the laparoscopic treatment of esophageal achalasia in nine patients over a 35-month period. Five trocars were used to perform a Heller's myotomy to completely eliminate the cardial high-pressure zone, under manometric control. Intraoperative manometry also was used to calibrate a pick degrees 360 Rossetti's antireflux wrap. A complete regression of symptoms was observed postoperatively in seven of nine patients (77.8%); in two patients (22.2%) a moderate dysphagia persisted, but it disappeared 3 and 6 months, respectively. Only one intraoperative complication (esophageal perforation, recognized and laparoscopically repaired) occurred. At the present follow-up of 18 +/- 5.34 months (range 6-35), no dysphagia or symptoms related to reflux have been observed. Laparoscopic treatment of esophageal achalasia is considered a safe and effective procedure, and the results of this procedure are comparable with those of the open technique. Advantages common to other laparoscopic techniques are emphasized.

Adolescent↗
PubMed1999

Button battery ingestion: hazards of esophageal impaction.

Ingestion of button batteries has been seen with increasing frequency over the past decade. In a small number of reported cases, their impaction in the esophagus has led to serious, sometimes fatal, complications. The management of these cases has varied from expectant, supportive therapy to early surgical intervention. The authors report 2 pediatric patients in whom esophageal perforation developed after impaction of a disc battery. Both were treated conservatively with successful outcomes.

Caustics↗
PubMed2006

[Spontaneous intramural dissection of the esophagus].

Spontaneous intramural dissection of the esophagus (SIDE) is an unusual clinical entity. It is a benign disease that, despite its alarming endoscopic appearance, usually responds well to conservative management and has an excellent prognosis. Nevertheless, some situations require emergency surgical treatment. These situations include esophageal perforation with mediastinitis, massive bleeding, and abscess, among others. Upper gastrointestinal endoscopy is a useful diagnostic test when radiological examinations (hydrosoluble contrast esophagogram, computed tomography, or magnetic resonance imaging) have excluded perforation. We present the case of a 42-year-old woman who was admitted to our hospital complaining of acute chest pain, dysphagia, and odynophagia. Because of the persistence of symptoms and diagnostic uncertainty (SIDE versus complicated esophageal duplication cyst) surgery was performed. The definitive diagnosis was SIDE.

Adult↗
PubMed1985

Exudative pleural effusions secondary to gastrointestinal diseases.

Several different diseases of the gastrointestinal tract may have an associated exudative pleural effusion. In the acutely ill patient with a pleural effusion, the possibility of esophageal perforation should always be considered. It is important to establish this diagnosis as soon as possible since the mortality rate increases markedly if drainage of the mediastinum is delayed for even 12 or 24 hours. The best screening test for esophageal rupture is the level of amylase in the pleural fluid. All patients with undiagnosed exudative pleural effusions should have the amylase level in their pleural fluid measured to rule out a pancreatic etiology for their pleural effusion. In patients with acute pancreatitis, the clinical presentation may be dominated by chest symptoms. Such patients have small to moderately sized pleural effusions that resolve rapidly once appropriate therapy is instituted. If symptoms persist, the possibility of a pancreatic abscess or a pancreatic pseudocyst should be considered. Patients with pancreatic pseudocysts may develop a sinus tract between the pseudocyst and the pleural space. In this situation a large pleural effusion develops. Frequently there are no abdominal symptoms and the diagnosis will not be made unless a pleural fluid amylase is obtained. Patients with exudative pleural effusions that contain predominantly polymorphonuclear leukocytes should be suspected of having an intra-abdominal abscess, particularly when there is no associated parenchymal infiltrate. Subphrenic, intrahepatic, and splenic abscesses all have a high incidence of accompanying pleural effusion. Abdominal CT scanning is the method of choice to establish each of these diagnoses.

Abdomen↗
PubMed2000

Fatal mediastinitis after routine laparoscopic cholecystectomy.

Laparoscopic cholecystectomy is now considered a routine operation with a low complication rate. In this case study, the authors present a laparoscopic cholecystectomy patient who died of masked mediastinitis and concomitant septicemia caused by an unrecognized esophageal perforation after difficult intubation. The authors call attention to the need for early detection of perforating mediastinitis to prevent a lethal outcome from this infrequent but life-threatening condition.

Brain Edema↗
PubMed2005

Endoscopic debridement of paraesophageal, mediastinal abscesses: a prospective case series.

BACKGROUND: Mediastinal abscesses after esophageal perforation or postoperative leakage nearly always require surgical intervention. METHODS: Patients with paraesophageal abscesses were treated with EUS-guided or endoscopic mediastinal puncture if the abscess was >2 cm and sepsis was present. Abscess cavities were entered with a 9.5-mm endoscope after balloon dilation to allow irrigation and drainage. Debris was removed with a Dormia basket. Concomitant pleural effusions were treated with transthoracic drains. Patients received intravenous antibiotics and enteral/parenteral nutrition. RESULTS: Twenty patients fulfilled the entry criteria. Simple drainage was sufficient in 4 cases, and puncture was impossible in one case. Of the 15 treated patients (age 39-76 years, 5 women) the etiology of perforation was Boerhaave's syndrome (n = 8), anastomotic leak (n = 3), and iatrogenic perforation (n = 4). Debridement was successful in all cases and required a median of 5 daily sessions (range 3-10). All patients became apyrexial, with a C-reactive protein < 5 mg/L within a median of 4 days (range 2-8 days). Esophageal defects were closed with endoclips (n = 7), fibrin glue (n = 4), metal stents (n = 1), or spontaneously healed (n = 3). One patient died from a massive pulmonary embolism one day after successful debridement (mortality 7%). No other complications were seen. Median follow-up was 12 months (range 3-40 months). CONCLUSIONS: Nonoperative endoscopic transesophageal debridement of mediastinal abscesses appears safe and effective.

Abscess↗
PubMed1987

Unusual presentations and complications of hairy cell leukemia.

In a series of 116 patients with hairy cell leukemia at the Ohio State University, followed for over 20 years, several unusual presentations and complications were encountered. The awareness of these unusual findings might be of help to investigators in the prompt diagnosis and treatment of this disease. The patients presented had, at the time of initial diagnosis, spontaneous rupture of spleen, cryptococcal meningitis, massive splenomegaly with hairy cell infiltration with normal peripheral blood and bone marrow examination, and marked leukocytosis. Some patients developed unusual complications during the course of their illness, such as gastric submucosal infiltration by hairy cells with secondary protein-losing enteropathy, spinal cord compression with paralysis, esophageal perforation with fistula tract, and massive ascites and pleural effusion with typical hairy cells present in the ascitic and pleural fluid.

Adult↗
PubMed1978

Ruptures and perforations of the esophagus: the case for conservative supportive management.

A series of 31 patients treated for ruptures and perforations of the intrathoracic esophagus is reviewed. Eighteen of these patients underwent major thoracotomy; 11 were treated with minor procedures. Two died before treatment could be implemented. Of the 18 undergoing major operations, 7 died; among the 11 managed conservatively there was only 1 death. Based on this experience, we conclude that major surgical repair for esophageal perforation is often unnecessary. It has the additional drawback of sometimes resulting in equally serious secondary procedures.

Esophageal Diseases↗
PubMed1975

Penetrating wounds of the cervical esophagus.

To determine trends in management, twenty-two years' experience with penetrating wounds of the cervical esophagus in thirty-nine patients has been evaluated. There were three deaths, all as a result of delayed operative repair. Experience gained from the earlier years of this study led to a marked reduction in mortality in the later years as a result of an increased index of clinical suspicion, coupled with an aggressive operative approach with primary closure and adequate drainage. A nonoperative approach has been suggested by others for small esophageal perforations after endoscopy and perforation from foreign objects. For penetrating injuries of the esophagus, operation and definitive repair is mandatory.

Adolescent↗
PubMed1996

Laparoscopic management of paraesophageal hernia: early results.

The objective was to review our early results with laparoscopic repair of paraesophageal hernias to determine the safety, technical feasibility, and short-term outcome of the operation. Twelve patients with a mean age of 75 +/- 1 years underwent laparoscopic repair of a paraesophageal hernia. Principles of open repair, including sac excision, primary crural repair, and pexy, were accomplished laparoscopically in 83%, 83%, and 100% of patients, respectively. In two patients the diaphragmatic defect was closed with mesh. Fundoplication was also performed in seven patients with symptoms of reflux disease. No laparoscopic procedure was converted to an open repair; however, one patient required a postoperative celiotomy to control hemorrhage. Short-term evaluation of all patients postoperatively detected gastroesophageal reflux disease (GERD) in five patients (42%), four of whom did not undergo fundoplication. Two major complications were esophageal perforation and bleeding. Minor complications included atrial fibrillation in two patients, meat impaction in one patient, and a small asymptomatic recurrence in a single patient. Overall patient satisfaction was high. Laparoscopic repair of paraesophageal hernias was safe and technically feasible and warrants further investigation. The incidence of postoperative esophageal reflux, however, is high if an antireflux procedure is not performed. Extensive preoperative evaluation for reflux should objectively identify patients requiring fundoplication and decrease the incidence of postoperative GERD.

Aged↗
PubMed1976

Esophageal obstruction due to intermuscular hematoma following pneumatic dilatation.

A case of incomplete esophageal perforation with an intermuscular hematoma is presented. Unlike previously described submucosal or intramural perforations, this case involved mucosa, submucosa, and the inner circular muscle layer but was limited by the outer longitudinal layer. Nonsurgical treatment was followed when the clinical picture of an incomplete perforation without mediastinal soilage was considered. Surgery was done when evidence of impending extension of the process outside the esophagus developed.

Adult↗
PubMedDate not supplied

Atraumatic perforation of the esophagus: current concepts and report of an additional case.

Truly atraumatic perforation of the esophagus is extremely rare. One such case with clinical features classic of this entity is reported. Characteristic findings of hydropneumothorax and pneumomediastinum on plain chest film, and the contrast esophagogram confirmed the diagnosis quickly. However, since the patient sought medical help late, with established septicemic shock, only closed chest drainage could be offered which proved grossly inadequate, and the patient died within 24 hours of presentation. As in the literature, this case report suggests that a case of esophageal perforation can easily and quickly be recognized on plain chest film, and that early aggressive surgical intervention in the form of open and wide mediastinal and chest drainage, with or without esophageal repair, resection or exclusion, offers the patients the best chances of survival against this otherwise invariably fatal event.

Adult↗