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PubMed1986

Simultaneous determination of cerebrospinal fluid oligoclonal bands and the "gamma-protein index" by agarose electrophoresis and densitometry.

Oligoclonal bands were identified in electropherograms of cerebrospinal fluid, and the "gamma-protein index" was concurrently calculated from the same strip. For the index, an upper limit of normal of 0.66 was established. We compared results with the clinical diagnosis in 69 patients with multiple sclerosis and 48 control patients with other diseases. Sensitivity, specificity, and positive predictive values of 73%, 96%, and 96%, respectively, were obtained from the index. An abnormal index and the presence of oligoclonal bands combined increased the positive predictive value to 100%. This approach may allow adequate qualitative and quantitative assessment of gamma-globulin abnormalities in cerebrospinal fluid after a single laboratory procedure.

Albumins↗
PubMed1989

[Linear bone densitometry by monochromatic photon absorptiometry. A study of a normal population in Apulia].

An epidemiological survey was conducted on a group of Apulian residents in order to compare the densitometric data obtained with those produced by other European and North American authors. The results confirm the need for personal data on our own population given the often significant differences in order to avoid errors in monitoring patients who may require even long-term treatment.

Absorptiometry, Photon↗
PubMed1989

[Densitometry of the bony structures of the human TMJ].

Four millimeter sagittal section of 65 formalin-fixed human TMJs were prepared. The X-rays of these specimen were evaluated numerically in a densitometer. The distribution of bone material and densities in condyle and fossa led to a classification of condylar and fossa types. In 48 specimen a combination of increased density of the condyle on the facial aspect with a thin bony lamella in the roof of the fossa, which either shows high density or very little material of low density, a so-called parchment fossa, was observed. The varying degrees of density as a function of mechanical stresses are discussed. The transfer of forces in the human TMJ during mastication exposes the superio-anterior or superio-facial segments of the condyle and the posterior slope of the articular tubercle to loading forces, while at the same time the roof of the fossa remains free of load.

Bone Density↗
PubMed1977

[Studies on the uses of the electronic image evaluating device "Densitron" for the evaluation of dental radiographs. III. Standardisation in densitometry].

The authors outline in two papers to what extent the interpretability of a radiograph is changed when converted by means of the Densitron. They confined themselves to the interpretation of dental films and panoramic radiographs. For reasons of clinical interest, particular attention was paid in dental films on localized processes (such as dental caries), and in panoramic radiographs on possible bone diseases as a sequel or concomitant affection in case of renal insufficiency, diabetes mellitus and hyperthyreosis.

Densitometry↗
PubMed1985

[Noninvasive study of the bone using single- and dual-photon densitometry: effects of age and menopause on bone density of normal and osteoporotic female population].

The assessment of bone status is so far usually performed by means of the relatively simple methods of radiographs and radiogrammetry, which are not always able to give a correct information about bone mineral content (B.M.C.) especially in cases of cortical osteoporosis. Among the other non-invasive methods, single- and dual-photon absorptiometry are of particular interest for their relatively low cost, precision, accuracy and repetitibility, giving the patient a very slight dose of radioactivity. Dual-photon device, in particular, offers the possibility to investigate B.M.C. in the bones surrounded with large amount of tissue, even in obese people. To assess bone status of feminine population, we have analyzed 238 patients, divided into 3 groups (normal pre- and post-menopausal women, and osteoporotic) measuring their radius and lumbar spine B.M.C. with single- and dual-photon absorptiometry. As a result, B.M.C. of both measuring sites appears closely correlated with age, and with the duration of menopause. In our group, cortical bone density showed a postmenopausal rate of loss higher than the trabecular. Vertebral measurements, too, were more closely correlated with age when corrected for body surface area. Osteoporotic group showed a B.M.C. significantly lower than the age-matched group of normal women both in spine and in radius: in conclusion, all these findings stress the importance of a widespread population surveillance in order to individuate and treat the patients at risk of spontaneous fractures.

Adolescent↗
PubMed1987

[Densitometry study of the Langerhans cells in human skin].

A densitometric study of Langerhans cells with ATPase technique is made. 62 samples of normal skin were studied. The buttocks and upper limbs showed the highest density of Langerhans cells. No differences related to age and sex were found.

Adenosine Triphosphatases↗
PubMed1977

[Mineral content of the skeleton in chronic kidney insufficiency treated with dialysis and after kidney transplantation. Results of isotope densitometry].

By means of a photon densitometer utilizing a 125I-source, bone mineral content was measured in 15 chronic renal failure patients on conservative management, 46 patients on maintenance hemodialysis and 20 patients after renal transplantation. The determinations were made at 4 sites in both radius and tibia. In patients with chronic renal failure on conservative treatment the bone mineral content did not differ significantly from that in normals. Patients on hemodialysis showed a low bone mineral content in 61 percent of females and 53 percent of males. Especially low values were obtained from 5 females who had undergone bilateral nephrectomy. After renal transplantation all female patients showed low values, whereas 50 percent of male patients showed decreased values. No correlations were found between bone mineral content and serum parameters (calcium, phosphate, alkaline phosphatase, creatinine), duration of renal failure, hemodialysis treatment or steroid medication.

Adult↗
PubMedDate not supplied

Automated densitometry of polyacrylamide gel electrophoregrams.

A device is described which enables to convert a spectrophotometer in a high performance densitometer. Test samples for the evaluation of densitometric characteristics are presented. The estimations can be carried out in the UV-visible range without applying the common staining procedure, on either cylindrical or plane gel plates in absorption or fluorescence. Polyacrylamide gel migrated commercial protein mixtures as well as A(H1N1) influenza virus and Sendai virus polypeptides were used as biological samples.

Densitometry↗