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[Retinoscopy under cycloplegic and non-cycloplegic conditions in children comparison of measurements of three examiners (author's transl)].

The refractive status of 100 eyes were measured by three ophthalmologists utilizing retinoscopy under non-cycloplegic and cycloplegic conditions. The statistical analysis of the results was done by multiple regression. The retinoscopic measurements of sphere and cylinder of the three examiners show smaller differences under cycloplegic than under non-cycloplegic conditions. The largest differences in the measurements of axis were found in cases of small cylinder power. Especially in children and in patients with strabismus, the authors feel that measurements of the refractive state have to be carried out under cycloplegia.

Accommodation, Ocular↗

[Objective determination of accommodation in eyes with permanent central scotoma due to amblyopia (author's transl)].

Objective determination of accommodation in 38 children with permanent central scotoma due to amblyopia on one side (with central and eccentric fixation) revealed: 1. The physiological adaptation of refraction for far and near distances did not serve its purpose. 2. There was either no or an irregular response on hyperopia, which was produced by placing concave lenses in front of the eye while fixing a far object, or on myopia produced by placing convex lenses in front of the eye while fixing a near object. 3. On hindering clear vision which could not be compensated by accommodation there was contrary to normal eyes no reactive change of refraction at all or only a poor one. The accommodation behavior in eyes with permanent central scotoma due to amblyopia does not differ from that in eyes with permanent central scotoma due to organic lesions when using the same test methods.

Accommodation, Ocular↗

Biperiden effects and plasma levels in volunteers.

The pharmacokinetics of biperiden was studied and compared with pharmacodynamics (pupil size, accommodation, self-rating mood scale) in 6 healthy volunteers. A single-blind cross-over design was employed with placebo and biperiden (4 mg as commercially available tablets). After a lag time of 0.5 h, biperiden was rapidly absorbed with a half-life of 0.3 h, plasma peak levels of 5 ng/ml being reached after 1.5 h. Biperiden showed good tissue penetration (distribution half-life 0.6 h; ratio of total to central distribution volume 9.6), the terminal half-life time of plasma concentration was 18 h, and the oral clearance was 146 l/h. The pharmacodynamic maximum lagged behind the plasma peak concentration by 1 (self-rating) to 4 h (accommodation).

Accommodation, Ocular↗

Crocodiles don't focus underwater.

Crocodilians are amphibious reptiles which hunt prey both on land and in water. Previous refractive and anatomical studies have suggested that their eyes can focus objects in air and that their ability to refocus the eye underwater may be limited. Examination of the plane of focus of six species of crocodilians both in air and underwater has revealed that they are generally well focused in air for distant targets and severely defocused underwater. These results suggest that sensory systems other than vision must play an important role in prey capture underwater.

Accommodation, Ocular↗

Fading and feedback in the modification of visual acuity.

Two experiments assessing the modification of visual acuity by fading plus feedback procedures are presented. The training procedure involved a gradual increase of the distance myopic subjects could accurately discriminate letters requiring a minimum of 20/20 vision at approximately 23 feet. In Experiment I experimental and matched control groups of mildly to moderately myopic subjects were compared on repeated Ortho-rater examinations of visual acuity. The experimental group showed a significant improvement relative to the control group who received no training. Multiple-baseline across-stimuli designs were used in Experiment II to evaluate training effects for another group of subjects with moderate to severe myopia. Two measures of acuity were obtained. Accuracy of discrimination of letters at various preselected distances was determined each session while Ortho-rater examinations were given periodically throughout training. Changes in discrimination accuracy over sessions appeared to be related to fading for three of the four subjects, and Ortho-rater acuity changes were observed for each subject. Some short-term maintenance of improved vision was evident on both acuity measures.

Accommodation, Ocular↗