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At least 91 records · Page 5Linked to original sources
PubMed1987

Lipoproteins status in professional football players after period of vacation and one month after a new intensive training program.

Plasmatic lipoproteins were evaluated in a group of 11 professional football-players after a 3-week rest, and one month later, after an intensive training (characterized by a succession of aerobic and anaerobic efforts), for engaging a new competition. At day 0, total cholesterol (TC = 4.4 +/- .04 mmol/l), triglycerides (TG = .6 +/- .04 mmol/l), and LDL-TC (2.54 +/- .18 mmol/l) were significantly decreased versus sex and age matched sedentary subjects (TC = 5.13 +/- .2 mmol/l, P less than .02; TG = .99 +/- . mmol/l, P less than .01; LDL-CT = 3.26 +/- .2 mmol/l, P less than .02). HDL-TC was increased (1.50 +/- .06 vs 1.30 +/- .05 mmol/l, P less than .05). The apoprotein A1 (apoA1) was higher in football-players (1.5 +/- .06 vs 1.16 g/l, P less than .001), while the apoprotein B (apoB) was lower (.6 +/- .03 vs .88 +/- .04 g/l, P less than .001). Even after 3 weeks of rest, the football-players lipoproteins were still identical to aerobic elite-athletes. At day +30, after a daily training involving 2 anaerobic sequences, the maximal aerobic capacity was increased by 21%, without any change in nutritional, plasmatic and hepatic status. Weight was diminished (-0.8 kg, P less than 0.05). TC (4.14 +/- .2 mmol/l), TG less than .64 +/- .08 mmol/l), LDL-TC (3.37 +/- .17 mmol/l), apo B (.64 +/- .05 g/l) were unchanged. HDL-CT fell to controls values while apoA1 increased (1.66 +/- .06 mmol/l, P less than .001). Thus, HDL-CT/apoA1 ratio (indicating the TC content of HDL) was decreased, whereas apoB/apoA1 ratio was unchanged. The decrease of TC content of HDL was not related to dietary change nor to weight decrease. As TG were stable, the lipoprotein lipase activity could not be modified.(ABSTRACT TRUNCATED AT 250 WORDS)

Adult↗
PubMed1990

Vacation diarrhea. How should it be managed?

Traveler's diarrhea in North America is most often a self-limited disease that requires little medical intervention unless the course is prolonged or especially severe. Diagnosis is almost always made by a stool examination or culture. The most common causative organisms are Campylobacter jejuni and Giardia lamblia. Enterotoxigenic Escherichia coli is a less frequent cause. Patients should be advised regarding the need for fluid replacement. Antibiotic therapy should be considered only in rare circumstances.

Adult↗
PubMed1997

A woman with a post-vacation rash.

A 52-year-old woman was admitted to the hospital with a rash, periorbital edema, dysphagia, and muscle weakness. The rash had appeared on the back of her neck nine months earlier, and because she had recently returned from a wildlife preserve on Assateague Island, Maryland, she assumed that it was due to tick bites. Over the next two months, the rash spread to her forehead, back, chest, and upper extremities, and scaly lesions appeared over metacar-pophalangeal joints. Initial laboratory tests indicated that her creatine kinase level was elevated. She was given prednisone and the level decreased. The rash also improved, but in the next two months the muscle weakness worsened. She became feverish and increasingly fatigued, depressed, and irritable. These later symptoms were attributed to the medication, but when she was weaned from it, her rash, weakness, and dysphagia increased. Over the ensuing months, she was given intramuscular injections of methotrexate (up to 25 mg/wk), followed by oral doses of hydroxychloroquine and azathioprine, but the symptoms persisted.

Antirheumatic Agents↗
PubMed2000

Mutation takes no vacation: can structured treatment interruptions increase the risk of drug-resistant HIV-1?

We use a mathematical model to study the dynamics of HIV-1 replication during structured treatment interruptions (STIs) in infected patients. The model predicts rapid viral rebound, restoration of a latently infected cell pool, and critically, partially resistant mutant rebound that may be missed because of high levels of wild type virus. Because partially resistant viruses are capable of mutating to full resistance, a substantial increase in their numbers represents a threat to therapeutic response durability. Compared with continued treatment, STIs may increase the chance of mutation to full resistance by several thousandfold.

Anti-HIV Agents↗
PubMed2000

Ecology. Weather ruins winter vacations.

There has been increasing concern over the decline in many migratory bird species. As Saether discusses in his Perspective, evidence is accumulating (Sillett et al.) that climate change resulting from the El Niño Southern Oscillation affects both the survival rate of adult birds at tropical wintering sites and their reproductive rate at summer breeding grounds in the Northern Hemisphere.

Animals↗
PubMed1974

Tropical vacation for paediatricians.

The purpose of two weeks spent in a developing country at relatively low cost ( pound145 each) was to have an enjoyable holiday while seeing something of the child health, culture, and economy of the country. Its deeper significance was to attract some participants to giving time and support to developing countries while making their teaching in Britain more relevant both to the native British student and to visitors from developing countries. There was no preaching. It was a "look, see, think" operation. Ghana was selected because of its friendliness, enthusiasm for the project, and helpful co-operation given in initial planning. The experience was judged successful by most and possibly by all. The friendly contacts established with very able Ghanaian colleagues may be mutually helpful in the field of medical education.

Developing Countries↗