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At least 91 records · Page 5Linked to original sources
PubMed1998

Assisted reproductive technology in the United States and Canada: 1995 results generated from the American Society for Reproductive Medicine/Society for Assisted Reproductive Technology Registry.

OBJECTIVE: To summarize the procedures and outcomes of assisted reproductive technology (ART) initiated in the United States and Canada in 1995. DESIGN: Data were collected in the Society for Assisted Reproductive Technology database program and cycle reporting forms and were submitted to the American Society for Reproductive Medicine/Society for Assisted Reproductive Technology Registry. PARTICIPANT(S): Two hundred eighty-one programs submitted data on procedures performed in 1995. Data were collected after November 1996 so that outcome of all pregnancies established would be known. MAIN OUTCOME MEASURE(S): Procedural outcomes measured included clinical pregnancy, ectopic pregnancy, abortion, stillbirth, delivery, and congenital abnormality. RESULT(S): Programs reported initiating 59,142 cycles of ART treatment, including frozen embryo and donor oocyte cycles. Of these, 41,087 cycles initiated were IVF (with and without micromanipulation) with 22.5% deliveries per retrieval; 3,741 were cycles of gamete intrafallopian transfer with 27.0% deliveries per retrieval; 1,078 were cycles of zygote intrafallopian transfer with 27.9% deliveries per retrieval. In addition to these cycles initiated in 1995, 8,453 frozen embryo thaw procedures were reported, either as separate procedures or in combination with other ART procedures with 15.2% deliveries per transfer, 3,555 donor oocyte cycles were initiated with an overall success of 36.0% deliveries per transfer, 1,028 cryopreserved embryo thaw procedures from donated oocyte procedures with an overall success of 16.8% deliveries per transfer, and 200 ART treatment cycles in which a host uterus was used were initiated with an overall success of 34.9% deliveries per ET. As a result of all procedures, a total of 11,631 deliveries were reported, resulting in 16,520 neonates. CONCLUSION(S): In 1995, there were more programs reporting ART treatment and a significant (19.3%) increase in reported cycles. In comparable cycle types, overall average success rates (deliveries per transfer) exhibited a 0.6% increase or a 2.5% increase over the rates in the 1994 reported summaries.

Adult↗
PubMed1999

Assisted reproductive technology in the United States: 1996 results generated from the American Society for Reproductive Medicine/Society for Assisted Reproductive Technology Registry.

OBJECTIVE: To summarize the procedures and outcomes of assisted reproductive technology (ART) initiated in the United States in 1996. DESIGN: Data were collected electronically using the Society for Assisted Reproductive Technology Clinical Outcome Reporting System software and submitted to the American Society for Reproductive Medicine/Society for Assisted Reproductive Technology Registry. PARTICIPANT(S): Three hundred programs submitted data on procedures performed in 1996. Data were collected after November 1997 so that the outcome of all pregnancies established would be known. MAIN OUTCOME MEASURE(S): Procedural outcomes measured included clinical pregnancy, ectopic pregnancy, abortion, stillbirth, delivery, and congenital abnormality. RESULT(S): Programs reported initiating 65,863 cycles of ART treatment, including frozen embryo and donor oocyte cycles. Of these. 44,647 cycles initiated were in vitro fertilization (IVF) (with and without micromanipulation) with 26.0% deliveries per retrieval; 2,879 were cycles of gamete intrafallopian transfer (GIFT) with 29.0% deliveries per retrieval; 1,200 were cycles of zygote intrafallopian transfer (ZIFT) with 30.9% deliveries per retrieval. In addition to these cycles initiated in 1996, 9,610 frozen embryo transfer procedures were initiated with 16.8% deliveries per transfer, 3,768 donor oocyte cycles were initiated with an overall success of 39.1% deliveries per transfer, 1,096 cryopreserved embryo transfers from donated oocytes procedures with an overall success of 20.8% deliveries per transfer, and 688 ART treatment cycles using a host uterus were initiated with an overall success of 31.3% deliveries per embryo transfer. Also, 1,341 cycles were reported as combinations of more than one treatment type, 19 cycles as research, 311 as embryo banking, and 304 as other (unclassified) cycle types. As a result of all procedures, a total of 14,702 deliveries were reported resulting in 21,196 neonates. CONCLUSION(S): In 1996, there were more programs reporting ART treatment and a significant (11.3%) increase in reported cycles. In comparable cycle types, overall average success rates (deliveries per retrieval) exhibited an actual increase of 3.5% (this is an increase of 15.8% when compared to the success rate for 1995).

Female↗
PubMed2001

Proteomics: a technology-driven and technology-limited discovery science.

An emerging field for the analysis of biological systems is the study of the complete protein complement of the genome, the 'proteome'. There are several complementary tools available for proteome analysis including 2D protein electrophoresis and mass spectrometry. Emerging technologies for proteome analysis include spotted-array-based methods and microfluidic devices. Taken together, these technologies provide a wealth of information that is useful in discovery-based science. However, there are some key limitations of these approaches and new technology is required to be able to fully integrate proteomic information with information obtained about DNA sequence, mRNA profiles and metabolite concentrations into effective models of biological systems.

Electrophoresis, Gel, Two-Dimensional↗
PubMedDate not supplied

Information technology for children's health and health care: report on the Information Technology in Children's Health Care Expert Meeting, September 21-22, 2000.

In September 2000, the Agency for Healthcare Quality and Research and the American Academy of Pediatrics Center for Child Health Research sponsored a meeting of experts and knowledgeable stakeholders to identify 1) the special information needs of pediatric care and 2) health service research questions related to the use of information technology in children's health care. Technologies that support the care of children must address issues related to growth and development, children's changing physiology, and the unique diseases of children and interventions of pediatric care. Connectivity and data integration are particular concerns for child health care workers. Consumer health information needs for this population extend beyond the needs of one individual to the needs of the family. Recommendations of the attendees include rapid implementation of features in electronic health information systems that support pediatric care and involvement of child health experts in policy making, standards setting, education, and advocacy. A proposed research agenda should address both effectiveness and costs of information technology, with special consideration for the needs of children, the development and evaluation of clinical decision support in pediatric settings, understanding of the epidemiology of iatrogenic injury in childhood, supplementation of vocabulary standards with pediatrics-specific terminology, and improvement in health care access for children, using telemedicine.

Child↗
PubMed2000

Is Intranet technology the low cost, quick fix solution for Scotland's clinical information technology chaos? Results of a pilot study.

For health care professional staff immediate access to recent clinical documents is seen as the first priority for developments in Information Technology. Large amounts of clinical data are held on computer systems to which staff have little or no access. A pilot study has been undertaken to evaluate the use of Intranet technology, electronically extracting large volumes of data from various feeder systems in real time and allowing access via standard Internet browsers. Over 700,000 reports have been successfully transferred from three differing sources with more than 2000 new records added per week. Intranet technology would seem to be a low cost solution, capable of rapid implementation, that could overcome the most important bottleneck in clinical computing.

Cost Control↗
PubMed2003

Technology trauma: barriers to increasing technology utilization.

While most social workers might agree that increasing the use of technology in agencies may be important for developing efficiency and effectiveness, little is known about the obstacles of doing so. In an NIDA-funded demonstration project to increase technology in agencies that serve drug abusing populations, researchers logged all email and memorandum communication for a two and a half year period. These communications documented the progress of the intervention from inception to implementation. Using a qualitative methodology, researchers for this analysis examined the communication documents, noting themes. A core theme focusing on barriers to implementing technology emerged from the data. These barriers included: agency personnel's lack of computer proficiency, lack of motivation for agency personnel to participate in the intervention, and agency personnel not following intervention protocols, having computer hardware and networking problems, the agency's physical structure (lack of space/computers), and the researchers/interventionists having restricted access to agency personnel.

Attitude to Computers↗
PubMed1999

NASA/DARPA advanced communications technology satellite project for evaluation of telemedicine outreach using next-generation communications satellite technology: Mayo Foundation participation.

OBJECTIVE: To describe the development of telemedicine capabilities-application of remote consultation and diagnostic techniques-and to evaluate the feasibility and practicality of such clinical outreach to rural and underserved communities with limited telecommunications infrastructures. MATERIAL AND METHODS: In 1992, Mayo Foundation (Rochester, Minn, Jacksonville, Fla, and Scottsdale, Ariz), the National Aeronautics and Space Administration, and the Defense Advanced Research Projects Agency collaborated to create a complex network of fiberoptic landlines, video recording systems, satellite terminals, and specially developed data translators linking Mayo sites with other locations in the continental United States on an on-demand basis. The purpose was to transmit data via the asynchronous transfer mode (ATM) digital communications protocol over the Advanced Communications Technology Satellite. The links were intended to provide a conduit for transmission of data for patient-specific consultations between physicians, evaluation of medical imagery, and medical education for clinical staffs at remote sites. RESULTS: Low-data-rate (LDR) experiments went live late in 1993. Mayo Clinic Rochester successfully provided medical consultation and services to 2 small regional medical facilities. High-data-rate (HDR) experiments included studies of remote digital echocardiography, store-and-forward telemedicine, cardiac catheterization, and teleconsultation for congenital heart disease. These studies combined landline data transmission with use of the satellite. The complexity of the routing paths and network components, immaturity of available software, and inexperience with existing telecommunications caused significant study delays. CONCLUSIONS: These experiments demonstrated that next-generation satellite technology can provide batch and real-time imagery for telemedicine. The first-generation of the ATM and satellite network technology used in these experiments created several technical problems and inconveniences that should be overcome as the network infrastructure matures.

Feasibility Studies↗
PubMed2003

Integrating mobile technology into a health professions curriculum: using flexible technology to meet expectations.

The diverse needs of students, faculty, administrators, and the curriculum itself, create formidable challenges when attempting to integrate mobile technology into a health professions curriculum. Single technology solutions often fail in this environment because they cannot meet user needs. Multiple platform and device agnostic solutions can provide the flexibility to address curricular needs without significantly adding technological complexity.

Computers, Handheld↗
PubMedDate not supplied

[Micro-array based technologies to study the proteome: technological progress and applications].

Since these twenty last years, there is an increasing interest for large-scale analysis of biological function. In the field of transcriptome, the emergence of microarray-based technologies and the design of DNA biochips allow high-throughput studies of RNA expression in cell and tissue at a given moment. In the field of proteome, methods of reference are still the 2D electrophoresis followed by analysis with mass spectrometry. Technological progress makes it possible to apply microarray methods to proteomics study : they are protein biochips or protein arrays. Expression analysis of proteins in a cell or a tissue in simultaneous and highly parallel way give further information for large-scale studies of signaling pathway. Numerous applications of protein microarray-based assays are described in basic biological research and in medical research to identify diagnostic biomarkers of inflammatory and cancerous pathologies and to find out news drugs and new therapeutic targets. This review summarizes concrete applications of microarray-based technology in the field of proteome, describes fundamental technical stages in protein array development and highlights critical points which will be useful to improve this emerging proteomic method.

Protein Array Analysis↗
PubMed2006

Health technology assessment. Findings from the Section on Assessing Information Technologies for Health.

OBJECTIVES: To summarize current excellent research in the field of health technology assessment. METHODS: Synopsis of the articles selected for the IMIA Yearbook 2006. RESULTS: Five excellent articles representing the research in four different nations were selected for the IMIA Yearbook 2006 from three international peer reviewed journals. CONCLUSIONS: The best paper selection for the Yearbook section 'Assessing Information Technologies for Health' presents papers evaluating the benefit and side-effects of information technology in various settings. They clearly indicate that benefit of IT in health care can be achieved when the systems are appropriately designed, implemented and operated. Besides the presented quantitative studies, also qualitative study designs are of value to find unintended effects of IT, or to better explain found effects. IT evaluation supports a reflective practice on how health informatics influences health care, enabling the emergence of an evidence-based health informatics.

Awards and Prizes↗
PubMed2002

Advances in space technology: the NSBRI Technology Development Team.

As evidenced from Mir and other long-duration space missions, the space environment can cause significant alterations in the human physiology that could prove dangerous for astronauts. The NASA programme to develop countermeasures for these deleterious human health effects is being carried out by the National Space Biomedical Research Institute (NSBRI). The NSBRI has 12 research teams, ten of which are primarily physiology based, one addresses on-board medical care, and the twelfth focuses on technology development in support of the other research teams. This Technology Development (TD) Team initially supported four instrumentation developments: (1) an advanced, multiple projection, dual energy X ray absorptiometry (AMPDXA) scanning system: (2) a portable neutron spectrometer; (3) a miniature time-of-flight mass spectrometer: and (4) a cardiovascular identification system. Technical highlights of the original projects are presented along with an introduction to the five new TD Team projects being funded by the NSBRI.

Absorptiometry, Photon↗
PubMed2004

New technologies for mechanical circulatory support: current status and future prospects of CorAide and MagScrew technologies.

Congestive heart failure remains a leading cause of morbidity and mortality in the United States, and alternatives to heart transplantation are urgently required. Mechanical circulatory support by ventricular assist devices and total artificial hearts have the potential to provide an alternative to heart transplantation if a small, durable, biocompatible, and totally implantable system is available. In this article, current technologies for mechanical circulatory support by implantable devices are reviewed and the current status and future prospects of the CorAide and MagScrew technologies, which have been developed and tested at the Cleveland Clinic Foundation, are presented.

Assisted Circulation↗
PubMed1990

Kaiser Permanente's New Technologies Committee: an approach to assessing technology.

Kaiser Permanente's New Technologies Committee reviews emerging technologies, evaluates their status as experimental or nonexperimental, and recommends coverage under specified circumstances. Kaiser Permanente developed a model for consensus and policy formation in its handling of the case of chorionic villus sampling, a now preferred alternative to amniocentesis for the detection of fetal defects.

Decision Making, Organizational↗
PubMed1998

The preliminary economic evaluation of health technologies for the prioritization of health technology assessments. A discussion.

This paper critically evaluates methods for the preliminary economic evaluation of health technologies and the prioritization of health technology assessment projects. It reports on the literature, and considers methods currently employed and the purposes of preliminary appraisal. It concludes that a preliminary economic appraisal needs to be applied to the two main stages of the prioritization process; to have transparent criteria; to allow for an appropriate range of potential outcomes; to be practicable, flexible, and efficient; and to be relevant to the assessment of different research projects.

Cost-Benefit Analysis↗
PubMed2006

Case study of the comparison of data from conference abstracts and full-text articles in health technology assessment of rapidly evolving technologies: does it make a difference?

OBJECTIVES: The aim of this study was to examine (i) the consistency of reporting research findings presented in conference abstracts and presentations and subsequent full publications, (ii) the ability to judge methodological quality of trials from conference abstracts and presentations, and (iii) the effect of inclusion or exclusion of data from these sources on the pooled effect estimates in a meta-analysis. METHODS: This report is a case study of a selected health technology assessment review (TAR) of a rapidly evolving technology that had identified and included a meta-analysis of trial data from conference abstracts and presentations. RESULTS: The overall quality of reporting in abstracts and presentations was poor, especially in abstracts. There was incomplete or inconsistent reporting of data in the abstract/presentations. Most often inconsistencies were between conference slide presentations and data reported in published full-text articles. Sensitivity analyses indicated that using data only from published papers would not have altered the direction of any of the results when compared with those using published and abstract data. However, the statistical significance of three of ten results would have changed. If conference abstracts and presentations were excluded from the early analysis, the direction of effect and statistical significance would have changed in one result. The overall conclusions of the original analysis would not have been altered. CONCLUSIONS: There are inconsistencies in data presented as conference abstracts/presentations and those reported in subsequent published reports. These inconsistencies could impact the final assessment results. Data discrepancies identified across sources included in TARs should be highlighted and their impact assessed and discussed. Sensitivity analyses should be carried out with and without abstract/presentation data included in the analysis. Incomplete reporting in conference abstracts and presentations limits the ability of reviewers to assess confidently the methodological quality of trials.

Congresses as Topic↗
PubMed2002

High technology and nursing: ethical dilemmas nurses and physicians face on high-technology units in Norway.

Results from two studies of ethical dilemmas nurses and doctors experience on two high-technology units are compared and discussed. The qualitative comparative methodology of grounded theory was used to generate theoretical frameworks grounded in the empirical realities of the units. The ethical dilemmas they faced were related to: treating the one vs. the common good; end of life questions; and resource allocations with inadequate staffing. Similarities were related to intensity and urgency of nursing care and patient treatment, clear nursing ideologies based on treating humans within a framework of hope, embracing technology and scarce resources. Differences between the two study units were patient diagnosis, hierarchical structure on one unit while one had a vertical structure and decision-making processes, and finally how nursing knowledge and autonomy were used. The two studies demonstrated that clinical, ethical and administrative interactions and decisions are highly compounded, stressful and intertwined.

Biomedical Technology↗
PubMed1983

Citrus fruits. Part II. Chemistry, technology, and quality evaluation. B. Technology.

In Part II of this review on citrus fruits, the literature on chemistry, technology, and quality evaluation are critically considered. Sweet oranges, mandarin, grapefruit, lemon, and lime are generally used for processing. The literature on chemical components of citrus fruit which include sugars, polysaccharides, organic acids, nitrogenous constituents and lipids; carotenoids which contribute to color; vitamins and minerals and flavonoids; limonoids, some of which impart bitterness to the juice; and the volatile components which contribute to aroma were reviewed in section A. Chilled and pasteurized juices, juice concentrates, and beverages are the important products manufactured commercially, and to a limited extent powdered citrus juices, canned segments, and marmalades. The literature on the manufacture of these products also as new types of juice and oil extractors; TASTE and other types of evaporators; tank farms to store juice and concentrate in bulk; aseptic filling in bulk containers and retail packs; alternate flexible and rigid containers other than glass and tin; and recovery of volatile flavoring constituents during juice processing are some of the important technological developments in the recent past and have been discussed in this section. Bitterness in citrus juices and its control, composition of cloud, and its stability and changes during storage have been reviewed. Essential oils, pectin, frozen and dried juice sacs, dried pulp and molasses, flavonoids, seed oil, and meal are the important byproducts, the manufacture of which is given in essential details. Generally, consumers judge the product on the basis of its sensory attributes. The quality of finished product is dependent upon the raw materials used and control of processes. In section C, the U.S. Department of Agriculture (USDA) standards for different products, physicochemical and microbiological parameters prescribed as indices of quality of fruit, juice, concentrate, and other products; composition of essential oils; and aroma concentrates are discussed in relation to sensory quality. Analytical methods for compounds affecting quality, and methods for detection of adulteration in different citrus products are briefly reviewed. The importance of sensorily evaluating quality of citrus products to select and develop quality control indices is emphasized. Areas where further research are required are indicated. A comprehensive bibliography is provided to aid further study and research.

Beverages↗
PubMed1996

Technology, deskilling, and nurses: the impact of the technologically changing environment.

This study examines the impact of three waves of technological change that swept nursing from 1950 to 1990. It suggests that the response to these changes was rooted in a positivistic stance toward skills as knowledge and a reiteration of culturally held views of natural feminine skills. It further argues that such a stance was inadequate to forestall deskilling and that a sociohistorical understanding of the cultural construction of both skill and gender provides a broader understanding of the impact of technological change.

History of Nursing↗