Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “Swayback”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 91 records · Page 5Linked to original sources

Enzootic ataxia of lambs and kids in the Ethiopian Rift Valley.

A syndrome of progressive ataxia leading to quadriplegia in young lambs and kids is described. The disease was characterised by high morbidity and mortality in affected flocks with annual recurrence and relatively limited geographical distribution. Hypocupraemia of lambs and ewes was very marked but there was no evidence of inflammatory or demyelinating disease in the brain and proximal cervical spinal cord nor of marked departures from normal haematological values.

Animals↗

Ultrastructure of hepatocytes in copper-deficient Sika deer (Cervus nippon Temminck).

The livers of 13 Sika deer (Cervus nippon Temminck) aged 4 to 9 years and suffering from copper deficiency (enzootic ataxia) were examined histologically, histochemically and by electron microscopy. In addition, the serum and liver copper concentrations, measured in three animals, were found to be low. Histologically, the hepatocytes exhibited cloudy swelling, and numerous haemosiderin deposits were seen in the hepatocytes and Kupffer cells. Staining with p-dimethyl amino-benzylidene-rhodamine revealed distinctly fewer copper granules than normal. Histochemically, 3,3'-diaminobenzidine-H2O2 staining revealed increased numbers of catalase-positive granules around nuclei. Electron microscopically, "giant" and bizarre-shaped mitochondria, irregular depression of the mitochondrial membrane, and fusion of cristae were noted. Disorders of copper-containing enzymes, including cytochrome oxidase, caeruloplasmin and monoamine oxidase, may have been responsible for the mitochondrial abnormalities.

Animals↗