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Is there seasonality in human ovulation?

To study seasonality in human ovulation in a direct way, we measured the occurrence of ovulation in infertile patients with spontaneous menstrual cycles (< 6 weeks) who visited the fertility clinic at the University Hospital Nijmegen in the Netherlands for the first time in 1991 or 1992 (n = 407). Ovulation was detected using serial transvaginal ultrasound and midluteal progesterone measurement and was performed during one screening cycle. The frequency of ovulatory cycles per month varied from 73% to 93% (not statistically significant). No seasonal pattern in ovulation was found in subfecund Dutch women with spontaneous menstrual cycles. This finding was not confounded by the effects of age of the women, body mass index, or disorders that could influence ovulation.

Adult↗

[Incidence and outcome of pregnancies with contraception].

In 1992, 1531 women aging 25-45 years from 5 urban and rural regions were interviewed about infertility and subfecundity within the German part of a study by the European community. 1248 of them had a positive reproductive history with 3018 pregnancies. 400 (= 13.25%) occurred during contraception. This affected 296 women (= 19.6% of all women). Smoking seems to have a promotion effect. The risk of ectopic pregnancies seems to be higher in contraceptive users. The highest fetal loss was found in women using an IUD. There were no differences in the course and outcome of pregnancy between users and nonusers of contraceptives. About 40% of the women in the corresponding group reported an irregular application of the contraceptive technique.

Adult↗

Infecundity and subfertility among the rural population of Ethiopia.

A 1980-81 survey of the rural population of Ethiopia found high levels of infecundity and subfertility, although there was considerable variation by region, ethnicity and age of women. Higher levels of infecundity were geographically concentrated in a broad belt that ran from the south and south-west of the country, across to the north-east. The analyses suggest that infecundity is influenced by ecological factors, more than by ethnicity.

Adult↗

Infertility treatment and multiple birth rates in Britain, 1938-94.

Trends in multiple birth rates are thought to have been substantially affected by subfertility treatments in the last 25 years, but there are few quantitative assessments of this. This paper examines trends in twin and higher multiple birth rates separately in Scotland, England and Wales and compares their course with corresponding multiple birth rates in the Oxford Record Linkage Study area, where the proportions following subfertility treatment are documented. National data on prescriptions for subfertility treatments reinforce the view that they have had a major effect on the trends, and currently perhaps 60% of triplet and higher order births and 15% of twins follow their use in Britain.

Birth Rate↗

Maternal factors of testicular cancer: a case-control study in Japan.

A case-control study was undertaken in Japan to clarify maternal or prenatal factors associated with testicular cancer. Information was obtained from 37 mothers of testicular cancer patients, recruited from the discharge records of nine hospitals in Hokkaido, the northern island of Japan. Thirty-seven mothers forming a control group were then surveyed at five public health centers. Each control was selected by individually matching the sex and birth year to a testicular cancer case. Univariate analysis revealed that there were no statistically significant differences in the variables surveyed. Multivariate logistic regression analysis, however, showed that case mothers had significantly fewer live-births than control mothers when the following four variables were adjusted (adjusted relative risk per live-birth = 0.43, P = 0.025): age at indexed birth, duration of breast-feeding for indexed child, birth order, experience of induced abortion.

Abortion, Induced↗

Childlessness, subfertility, and infertility in Tanzania.

This study examines the trends and variations in childlessness, subfertility, and infertility in Tanzania according to data from the 1973 National Demographic Survey and the 1991-92 Demographic and Health Survey. Between the surveys, the proportion of women older than 30 who were childless was found to have declined more than 60 percent, and the proportion with an open birth interval extending for longer than five years was reduced by 40 to 50 percent in each standard five-year age group from 20 to 39. Within Tanzania, both childlessness and infertility are higher among urban than rural residents, and a substantial range prevails across eight rural zones. Finally, evidence suggests that the decline in impaired fertility has been followed by an increase in the total fertility rate. The difficulties of implementing population policies that aim simultaneously to control population growth and to improve women's health are discussed.

Adolescent↗