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The accuracy of anterior-posterior measurements in the assessment of spinal canal compromise in burst fractures.

The amount of spinal canal compromise is one of the primary criteria employed to specify treatment of thoracolumbar burst fractures. Canal compromise has been calculated utilizing measurement of anterior-posterior canal or by calculating the area of the involved spinal canal on CT scans. Since these measurements are critical to surgical decision making, we have compared anterior-posterior measurements with area measurements to assess the variability between these two techniques. Three mm axial CT scans from ten patients with thoracolumbar burst fractures were studied. The axial CT images at the midpoints of the vertebral bodies at the levels above and below the fracture level, and the axial CT image demonstrating the most significant canal compromise at the fracture level were digitized using an optical scanner. Using the image 1.43 software, the anterior-posterior dimensions and area dimensions of each axial CT scan were obtained and the amount of canal compromise calculated. Linear measurements consistently overestimate the extent of spinal canal compromise as compared to the true area of canal compromise (6-46%, p < 0.005). This amount of variation did not correlate with the level, patient age or the extent of canal compromise. This preliminary study suggests that the two measurement techniques used to guide surgical decision making are not comparable. Further evaluation comparing the use of linear and area measurements is warranted.

Humans↗

Morphologic analysis of the cervical spinal cord, dural tube, and spinal canal by magnetic resonance imaging in normal adults and patients with cervical spondylotic myelopathy.

STUDY DESIGN: Transverse areas of the spinal canal, the dural tube and the spinal cord of the cervical spine of normal adults and patients with cervical spondylotic myelopathy (CSM) were analyzed by magnetic resonance imaging (MRI). OBJECTIVES: Correlations of the results of MRI to clarify the pathogenesis of CSM. SUMMARY OF BACKGROUND DATA: Relationships between the area of the spinal cord and that of the dural tube or the spinal canal have been reported, but there is no report to compare the relationships among the three in patients with CSM and normal adults. METHODS: T1-weighted MR images of the cervical spine of 96 normal adults and 74 patients with CSM were evaluated by measuring the transverse areas of the three structures mentioned above in the axial plane. RESULTS: In normal adults, the maximal transverse area of the spinal cord was 85.8 mm2 at C4/5 and the minimal transverse areas of the dural tube and the spinal canal were 186.0 mm2 at C5/6 and 236.1 mm2 at C4, respectively. At the unaffected level of C3, the ratio of the canal to the spinal cord was significantly higher in CSM patients than in age-matched normal adults. The transverse area of the spinal cord and the ratio at the maximal compression level showed significant correlations with the severity of neurological symptoms. CONCLUSION: These results suggest that the narrow area and high ratio of the spinal canal to the spinal cord are responsible for a static factor in CSM.

Adult↗

Air in the spinal canal associated with trauma.

Air in the spinal canal after trauma is uncommon. We report a case of a motor vehicle accident resulting in a thoracic fracture-dislocation. Air was discovered within the spinal canal on a computed tomography (CT) scan. This injury pattern proved to be a diagnostic dilemma because multiple etiologies existed. Pneumothorax, ruptured esophagus, facial sinus fractures, and herniated vertebral discs can result in this entity.

Accidents, Traffic↗

Migration of a bullet in the spinal canal.

Migration of a bullet within the spinal canal after gunshot injury is rare. We report here the case of a penetrating gunshot injury of the lumbar spine at L3 with migration of the bullet within the spinal canal S2. The patient had marked paraparesis (proximal 1/5, distal 0/5 muscle strength) and anaesthesia at L3 and below, and had a hypocompliant, hyper-reflexive bladder with decreased capacity, and absent anal tonus. We removed osseous fragments in the canal with an L3 laminectomy and extracted the bullet by S2 laminectomy. After surgery, we observed an improvement in paraparesis, an increase in bladder capacity and urinary compliance, and improvement in anal tonus. The appropriate course of action in this type of injury remains unclear, because the number of cases described in the literature is not sufficient to provide a basis on which to make a definitive therapeutic decision. We herein review the literature describing cases in which a bullet in the spinal canal has migrated; we describe the treatment used and the outcomes in these cases.

Adult↗

Decreased width of the spinal canal in patients with chronic symptoms after whiplash injury.

STUDY DESIGN: The sagittal diameter of the cervical spinal canal was measured on standard lateral radiographs of 48 consecutive patients with acute whiplash injury. A follow-up was done 12 months after injury. OBJECTIVES: The purpose of this study was to evaluate the relationship between spinal canal width and chronic symptoms after whiplash injury. SUMMARY OF BACKGROUND DATA: A narrow sagittal diameter of the cervical spinal canal has been correlated with neurologic deficits in degenerative conditions and after fractures. The authors are not aware of previous studies on whiplash patients related to this area. METHODS: Forty-eight consecutive patients were evaluated for whiplash trauma after car accidents. Twenty-four patients (12 men and 12 women; mean age, 37 years) had persistent symptoms after 12 months, while 24 patients (12 men and 12 women; mean age, 34 years) were asymptomatic. All measurements were done from standard lateral radiographs with a graphic digitizer connected to a microcomputer. Three anteroposterior and one oblique measurement of the canal were reconstructed for each vertebrae from C2-C6. Multivariate analysis of variance was used to evaluate any association between gender, remaining symptoms at follow-up, and the recorded values of the spinal canal width. RESULTS: The spinal canal was significantly smaller in the patients with persistent symptoms than in the asymptomatic group. A significant difference also was found between men and women. CONCLUSION: Narrow diameter of the cervical spinal canal is unfavorable in patients with whiplash.

Adult↗

[Developmental stenosis of the cervical spinal canal hyperextension injury].

Sixteen cases of cervical spinal cord injury with developmental stenosis of cervical spinal canal were treated. The numbness and quadriplegia of the patients were caused by hyperextension X-ray of the cervical spine showed no fracture or dislocation but the sagittal diameter of the canal and that of the corresponding cervical vertebral body was less than 0.75. All of the patients were treated by operation including laminoplasty on 12 cases. The numbness and quadriplegia in most of the patients were improved obviously after operation. The mechanism of hyperextension injury on the cervical spinal cord was discussed. When spinal column was extended, annulus fibrosus of disk and ligamentum flavum would enfold into the spinal canal and only a slight force would do severe on the cord. Laminoplasty is the recommended treatment for this kind of lesions.

Adult↗

Roentgenological study of the sagittal diameter of the cervical spinal canal in normal adult Japanese.

The sagittal diameter of the cervical spinal canal on roentgenograms in normal adult Japanese aged 15 years or over, 505 males and 492 females, was investigated to define the normal distribution and lower limit. Lateral roentgenograms of cervical spinal canals were taken at a constant focus-film distance of 1.5 m. The mean +/- SD magnification coefficient was 1.17 +/- 0.02. The mean +/- SD sagittal diameters of the cervical spinal canals at each vertebral level were: C-1, 21.0 +/- 2.2 mm; C-2, 18.0 +/- 1.7 mm; C-3, 15.8 +/- 1.5 mm; C-4, 15.2 +/- 1.5 mm; C-5, 15.3 +/- 1.5 mm; C-6, 15.7 +/- 1.5 mm; and C-7, 15.9 +/- 1.4 mm. The lowest mean -2 SD values were: C-1, 16.6 mm; C-2, 14.6 mm; C-3: 12.8 mm; C-4, 12.2 mm; C-5, 12.3 mm; C-6, 12.7 mm; and C-7, 13.1 mm. The smallest diameter was at the C-4 level, but there was no significant difference between values at the C-4 and C-5 levels. Males had significantly larger diameters than females (mean difference 0.8 mm) (p < 0.01). Younger subjects had greater diameters than older subjects. The incidence of spondylotic changes was 40.1% in subjects aged 50-59 years, 57.7% in those aged 60-69 years, and 76.6% in those aged 70-79 years. Males had a higher incidence than females. Ossification of the posterior longitudinal ligament was observed in 2.1% of all subjects. This study suggests that patients with a sagittal diameter in the cervical spinal canal of less than 12 mm have a high risk of cervical myelopathy.

Adolescent↗

A review of biomechanics of the central nervous system--Part I: spinal canal deformations resulting from changes in posture.

OBJECTIVE: To discuss how the spinal cord deforms as a result of changes in posture or biomechanical alterations of the spine. DATA COLLECTION: A hand search of available reference texts and a computer search of literature from the Index Medicus sources were collected, with special emphasis placed on spinal canal changes caused by various postural rotations and translations of the skull, thorax, and pelvis. RESULTS: All spinal postures will deform the spinal canal. Flexion causes a small increase in canal diameter and volume as the vertebral lamina are separated. Extension causes a small decrease in canal diameter and volume as the vertebral lamina are approximated. Lateral bending and axial rotation cause insignificant changes in spinal canal diameter and volume in cases without stenosis. CONCLUSIONS: Rotations of the global postural components, head, thoracic cage, and pelvis cause changes in the diameter of the spinal canal and intervertebral foramen. These changes are generally a reduction of less than 1.5 mm in extension, compared with a small increase in flexion of approximately 1 mm. These small changes do not account for the clinical observation of patients having increased neurologic signs and symptoms in flexion.

Biomechanical Phenomena↗

Changes of cervical spinal cord and cervical spinal canal with age in asymptomatic subjects.

STUDY DESIGN: Prospective study on magnetic resonance imaging (MRI) and radiographic findings of the cervical spine. OBJECTIVE: To elucidate the age-related changes of the cervical spinal cord and the cervical spinal canal and the relationship between the spinal cord and the spinal canal in asymptomatic subjects using MRI and radiography. SETTING: Tokyo, Japan. METHODS: The transverse area of the cervical spinal cord and the ratio of the anteroposterior diameter to the transverse diameter (RAPT) were investigated, using MRI in 229 asymptomatic subjects. The sagittal spinal canal diameter and anteroposterior diameter of the cervical vertebral body were also measured on plain lateral radiographs. The canal body ratio (CBR), which was defined as the diameter of the spinal canal divided by that of the vertebral body, was calculated. RESULTS: The transverse spinal cord area correlated negatively with age. RAPT did not correlate with age. The CBR correlated negatively with age. The correlation between spinal cord area and CBR was significant but weak and the correlation between RAPT and CBR was not significant. CONCLUSION: The transverse area of the cervical spinal cord measured by MRI decreased with age, while RAPT remained unchanged. The bony spinal canal became narrower with age. The spinal cord area and the shapes of the spinal cord were independent from the spinal canal diameter in asymptomatic subjects. These facts should be considered when evaluating radiological findings in patients with cervical spinal disorders.

Adolescent↗

Thoracolumbar burst fractures: CT dimensions of the spinal canal relative to postsurgical improvement.

Cross-sectional spinal canal area was measured before and after surgery in 12 patients with thoracolumbar burst fractures and canal narrowing caused by retropulsed fragments. Patients were classified into Denis type A or type B. Denis type A fractures have comminution of both end-plates of the vertebral body creating multiple smaller fractures; Denis type B fractures have comminution of the superior end-plate only with a single vertical fracture line into the inferior end-plate creating larger fragments. The degree of neurologic impairment was assessed before and after surgery using the Frankel system. There was no correlation between degree of canal narrowing and degree of neurologic impairment. The degree of spinal canal narrowing reflects the final resting position of the vertebral body fragments after trauma; during trauma, greater degrees of canal impingement may have occurred. Also, significant canal narrowing may be present without pinching of the cord or cauda equina. All patients with Denis type A fractures had near-anatomic reduction of fragments out of the spinal canal by surgery; less than half of the patients with Denis type B had good reduction. There was no correlation between reduction of retropulsed fragments and subsequent neurologic improvement. However, this should not preclude surgery as a therapeutic option: Eight of 10 patients with neurologic impairment experienced some improvement in symptoms after surgery; the other two were unchanged.

Adult↗

Quantitative changes in spinal canal dimensions using interbody distraction for spondylolisthesis.

STUDY DESIGN: An experimental study was performed using cadaveric lumbar spines to evaluate the effect of anteriorly or laterally placed interbody distraction implants on the alteration of spinal canal and neuroforaminal dimensions. OBJECTIVES: To quantify changes in the spinal canal and neuroforaminal dimensions using interbody fusion devices inserted at various configurations in cadaveric lumbar spines exhibiting degenerative spondylolisthesis. SUMMARY OF BACKGROUND DATA: Although several clinical studies have demonstrated successful treatment of degenerative spondylolisthesis with anterior interbody fusion, no study has shown the role of interbody distraction in improving lumbar spinal canal and foraminal stenosis. METHODS: Five fresh cadaver lumbar spines exhibiting a degenerative spondylolisthesis or retrospondylolisthesis were used for the study. Computed tomography scans of each specimen and a silicon mold of the left intervertebral foramens were repeated in a consistent manner after pure compressive load (150 lb) was applied to simulate physiologic load (intact case), after two BAK (Sulzer SpineTech Inc., Minneapolis, MN) distraction plugs were anteriorly inserted into the intervertebral disc space (anterior distraction cases), and after one long BAK cage was laterally inserted from the left side (lateral distraction case). The cross-sectional area of the spinal canal was measured from computed tomography images using National Institutes of Health image software (Bethesda, MD). The spinal canal volume was calculated using the cross-sectional area and total scan thickness. Left intervertebral foraminal volumes were calculated from the weight of the silicon mold injected into the foramen. Descriptive statistics and a Student's t test were used to detect statistical differences in the spinal canal and neuroforaminal volumes before and after interbody distraction. RESULTS: The cross-sectional canal area was significantly increased after anterior distraction (35.11%) and lateral distraction (33.14%). The spinal canal volume was markedly increased with anterior distraction (19.92%) and lateral distraction (21.96%). Left foraminal volume was also enhanced by 40.25% for anterior distraction and 41.03% for lateral distraction. CONCLUSIONS: Interbody distraction either by anteriorly inserted plugs or laterally inserted threaded cagescan immediately improve the narrowed canal area and increase spinal canal, as well as foraminal volume for lumbar degenerative spondylolisthesis or retro- spondylolisthesis.

Anthropometry↗

Observer variability in assessing lumbar spinal stenosis severity on magnetic resonance imaging and its relation to cross-sectional spinal canal area.

STUDY DESIGN: Magnetic resonance image grading of lumbar spinal stenosis severity was analyzed retrospectively using a common clinical format. OBJECTIVE: To assess the interobserver and intraobserver reliability of magnetic resonance image used to grade patients with lumbar spinal stenosis, as compared with cross-sectional spinal canal area. SUMMARY OF BACKGROUND DATA: Physicians currently classify the degree of lumbar spinal stenosis on magnetic resonance imaging as mild, moderate, or severe. Unfortunately, there is no consensus on criteria for these definitions. METHODS: The magnetic resonance image scans of 15 patients with lumbar stenosis were blindly rated by seven observers for the degree of central, lateral recess, and foraminal stenosis between L1-L2 and L5-S1. Weighted kappa statistics were performed to analyze the inter- and intraobserver agreement. Digitized spinal canal area measurements were calculated. Linear regression models were used to assess the reliability of the grading system in predicting the cross-sectional area. RESULTS: The average interobserver kappa score was 0.26. Within different specialties, the interobserver reliability was higher among radiologists (0.40), followed by neurosurgeons (0.21) and orthopedic surgeons (0.15). The average intraobserver kappa score was 0.11, rising to 0.43 after categories were combined (P = 0.001). The classification of central stenosis highly predicted spinal canal area (P < 0.001). CONCLUSIONS: The findings indicate only a fair level of agreement among all observers. However, the ability of the various readers to predict the degree of central stenosis was high. Further studies should evaluate a consensus-based, standardized magnetic resonance image classification aimed at improved agreement among observers.

Humans↗

The spinal canal in familial spastic paraplegia.

The elucidation of possible involvement of the vertebral canal in familial spastic paraplegia is attempted. The sagittal and the transverse diameters of the cervical, thoracic and lumbar vertebral canal were estimated in 14 patients and 100 controls. The results showed that the vertebral canal of the patients is considerably smaller in its whole length and not only in the thoracic region. This finding is discussed in relation to the development of both the vertebral canal and spinal cord.

Adult↗

[Reaction of spinal epidural venous plexuses of the spinal canal in low back spinal discopathy].

Clinical ultrasonic investigations have shown dependence of blood-stream in spinal epidural venous plexuses on the character of low back spinal diskopathy. The leading starting factor of epiduritis is a disk protrusion or large size hernia. Epiduritis in disscopathy can run a chronic course, become a cause of (or complicate) development of vertebral neurological reflex or compression syndromes. One of acceptable diagnostic methods for local epiduritis is an ultrasonic technique which is a valuable adjunct to clinical studies.

Adolescent↗

Soft cervical disc herniation. Influence of cervical spinal canal measurements on development of neurologic symptoms.

STUDY DESIGN: In 100 consecutive patients who underwent surgery because of soft cervical disc herniation, the sagittal and transverse diameters, the area of the bony cervical spinal canal, the sagittal diameter of the hernia, and the minimal bony intervertebral foramen diameter were measured by computed tomography. The data were compared with measurements from a control group of 35 matched healthy individuals. OBJECTIVES: To evaluate the relation between the severity of concurrent neurologic symptoms and the sagittal and transverse diameters, the cross-sectional area of the bony spinal canal, the sagittal diameter of the hernia, and diameter of the minimal bony intervertebral foramen in patients with soft cervical disc herniation. SUMMARY OF BACKGROUND DATA: Traumatic injury and spondylotic changes have a far greater impact on the spinal cord and nerve roots if the sagittal diameter of the bony cervical spinal canal is small. However, in the case of soft cervical disc herniation, no computer tomographic measurements are available for sagittal and transverse diameters, cross-sectional area of the bony spinal canal, sagittal diameter of the hernia, and diameter of the minimal bony intervertebral foramen in relation to the severity of concurrent neurologic symptoms. METHODS: Computed tomography was used to measure sagittal and transverse diameters, cross-sectional area of the bony cervical spinal canal, sagittal diameter of the hernia, and diameter of the minimal bony intervertebral foramen in 100 patients with symptomatic monosegmental cervical soft disc herniation. All patients had undergone an anterior discectomy with removal of the hernia and subsequent interbody fusion using an autologous bone graft taken from the iliac crest. RESULTS: A mean sagittal diameter of the bony cervical spinal canal of 12.9 mm was found, indicating a certain degree of developmental stenosis. Patients with motor disturbances had a significantly smaller sagittal diameter of the bony spinal canal than did patients without motor disturbances. There was a linear correlation between the sagittal diameter of the bony cervical spinal canal and that of the hernia. The sagittal diameter, the area of the bony spinal canal, and diameter of the minimal bony intervertebral foramen were significantly smaller in patients with soft cervical disc herniation than in the control group. CONCLUSIONS: Results from this study strongly suggest that the degree and severity of neurologic symptoms accompanying cervical soft disc herniation are inversely related to the sagittal diameter and the area of the bony cervical spinal canal. The latter area is reduced in cases of developmental stenosis or because of soft disc herniation. Moreover, patients with soft cervical disc herniation have a significantly smaller sagittal diameter of the bony spinal canal, a significantly smaller minimal bony intervertebral foramen diameter, and a significantly smaller cross-sectional area of the bony cervical canal than do healthy matched individuals.

Cervical Vertebrae↗

Indirect spinal canal decompression in burst fractures treated with pedicle screw instrumentation.

STUDY DESIGN: Prospective evaluation of spinal canal areas in 67 consecutive burst fractures between T12 and L2 treated by reduction and stabilization with a pedicle fixator. OBJECTIVES: Assessment of the efficacy of "indirect" spinal canal decompression in a large series of burst fractures. SUMMARY OF BACKGROUND DATA: Up to 50% of burst fractures cause neurologic impairment. Reduction and posterior instrumentation is the most common surgical treatment. This also reduces spinal canal encroachment by indirect decompression. No consensus exists as to the consistency and adequacy of such indirect decompression. METHODS: Spinal canal areas were measured on preoperative and postoperative computed tomography scans. The degree of encroachment was compared with clinical and radiographic variables for possible correlation. RESULTS: Spinal canal encroachment was more severe among patients with neurologic deficits than among the neurologically intact. Postoperatively, mean encroachment was reduced from 35% to 12% at T12, from 37% to 17% at L1, and from 52% to 35% at L2. Loss (and postoperative restoration) of anterior vertebral height correlated best with the degree of canal encroachment (and its reduction), especially in Denis Type A burst fractures. In Denis Type B fractures, canal compromise usually was less severe and fragment reduction better in patients older than 40 years of age than in younger patients. CONCLUSIONS: Indirect decompression in burst fractures averages about half of the preexisting encroachment. Results are usually better at T12 and L1 than at L2. Additional or secondary decompression is rarely indicated if these fractures are treated early and by experienced surgeons. Burst Type B fractures in patients older versus younger than 40 years of age differ in many respects.

Adult↗

Residual deformity of the spinal canal in patients with traumatic paraplegia and secondary changes of the spinal cord.

INTRODUCTION: The effect of spinal deformity with posttraumatic kyphosis and stenosis of the spinal canal in producing secondary changes of the spinal cord has been discussed for quite some time. Since the advent of magnetic resonance imaging (MRI), 20-40% of patients with posttraumatic paraplegia are found to develop hydromyelia. PURPOSE OF OUR STUDY: To evaluate the influence of residual spinal deformity, defined by the extent of the posttraumatic kyphosis and stenosis, in the development of posttraumatic hydromyelia. MATERIAL AND METHODS: Two hundred and seven cases of traumatic paraplegia with MRI follow-up were reviewed retrospectively. A minimum of 3 years duration between trauma and MRI study was required (mean 10.6 years [3.2-38.3]). For statistical analysis two groups of patients were formed: with hydromyelia and without hydromyelia. After healing of the fracture, the extent of the kyphosis and stenosis, as well as the characteristics of the paraplegia were noted. RESULTS: We found that 53 patients had hydromyelia. A highly significant correlation was found for the extent of spinal stenosis and the amount of kyphosis. Cluster analysis indicated that patients with more than 15 degrees of posttraumatic kyphosis and more than 25% of stenosis were twice as likely to develop hydromyelia. The level of the lesion and the remaining neurological function was not proven to have any influence towards the development of hydromyelia. CONCLUSIONS: These results support the idea that chronic mechanical stress to the spinal cord increases the risk for the development of hydromyelia. Surgical reconstruction should be considered for all patients to prevent secondary changes of the spinal cord.

Adolescent↗

The MR appearance of CSF pulsations in the spinal canal.

We investigated the MR appearance and incidence of low-signal areas within the CSF of the spinal canal. Nonuniform areas of decreased signal intensity in intracranial CSF have been named the CSF flow-void sign (CFVS) and appear to be due to spin dephasing secondary to pulsatile CSF motion. Similar areas are seen in the spinal canal. The MR scans of 50 randomly selected patients, constituting a total of 63 spinal studies, were reviewed. There were 27 cervical, 16 thoracic, and 20 lumbar spine examinations. All patients were studied using T2-weighted and T1-weighted spin-echo pulse sequences. T2-weighted images were done with sufficiently long TE and TR to cause the CSF to appear hyperintense compared with brain and spinal cord tissue. Two patients with enlarged spinal canals and two patients with syringohydromyelia were also included to illustrate the appearance of prominent CSF pulsations. The CFVS was identified on T2-weighted scans in the cervical spinal canal in nine patients (33%), in the thoracic spinal canal in one patient (6%), and possibly in the lumbar spinal canal in two patients (10%). The CFVS was prominent in two patients with enlarged CSF spaces and was also seen in the intramedullary cavity of the patients with syringohydromyelia. The CFVS could obscure small dural lesions and, in some instances, simulate enlarged vessels. Recognition of the spinal CFVS is important to avoid the incorrect diagnosis of intraspinal lesions.

Adolescent↗