Atypical cells in spermatocele fluid.
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A cup-shaped silicon prosthesis was developed to treat patients with excretory azoospermia and chemical management of the aspirated spermatozoa was attempted prior to cervical insemination of the wives. These cup-shaped prostheses were implanted eight times in six patients, four of whom had congenital absence and two of whom had bilateral inflammatory obstruction of the vas deferens. The surgical technique was based on the method of Cruz (1980), which involved wrapping the tunica vaginalis over the top of the prosthesis. Aspirated spermatozoa were incubated in a modified Ringer's solution at 37 C for 30 minutes and used for the cervical insemination of the wives. Epididymal spermatozoa could be collected from all patients 10 to 20 weeks after the operation. The percentage of motile aspirated spermatozoa ranged from 0 to 20%. In two cases, the percentage of motile spermatozoa aspirated from the prosthesis increased markedly from 5 and 10% to 55 and 60%, respectively, after incubation of the spermatozoa in the medium. Cervical inseminations were tried in all of the wives from two to four times, but no pregnancy resulted during this study.
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During the last 4 years we succeeded in proving in experiments in rats and bulls that a cup-shaped silicone-dacron prosthesis may be used as Sperm-reservoir. Spermatozoa--aspirated from this reservoir and stored as pellets in liquid nitrogen over 6 weeks--induced pregnancies and normal births in 50 percent of inseminated cows. Because of aplasia or long stenosis of the vas deferens 26 prostheses (20 X 8 X 8 mm) were implanted upon the epididymis in 14 patients. Percutaneous aspirations up to 7 months after operation showed up to 105 million spermatozoa persingle aspiration. The number and the motility of the aspirated spermatozoa varied considerably from one puncture to the next. Quality and quantity of spermatozoa decreases in correlation with longer postoperative delays. Average aspiration-time was 3 months and positive sperm counts were obtained on an average for 2 months. Insemination of the patients' wives with the aspirate did not result in any pregnancy so far. In "hopeless cases" presenting excretory azoospermia and aplasia or long stenosis of the vas, we try to obtain maximal numbers of spermatozoa by early and frequent aspiration of the implanted alloplastic reservoir for well "timed" direct insemination and deepfreezing.
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Because scrotal masses may be a source of embarrassment for adolescents concerned about fertility and sexual prowess, supportive counseling should be included in treatment. The authors summarize the history, pathophysiology, epidemiology, natural history, signs and symptoms, laboratory tests, diagnostic problems, treatment, and prognosis of these masses.