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PubMed2002

An effective workplace stress management intervention: Chicken Soup for the Soul at Work Employee Groups.

Stress is a costly and significant source of health problems and mental distress--with work cited as a primary stressor. This pilot study supports the effectiveness of a new workplace stress intervention: Chicken Soup for the Soul at Work Employee Groups. In this program, employee-participants met during nine weekly meetings to read inspirational workplace stories, comment, and share their own stories. A leader, chosen from and by the group, guided meetings. Utilizing a wait-list control group design, participants were randomly assigned to an experimental or wait-list group. Participants completed pretests and posttests (Coping Resources Inventory, Occupational Stress Inventory-Revised, Job Descriptive Index, Pressure Management Indicator, survey). Statistical interaction effect for subtests was evaluated using a two-way repeated measures analysis of variance. Participants exhibited improved total coping resources, cognitive/rational coping, state of mind, confidence and home/work balance. Participant comments and their continued participation in a similar company-sponsored program bolster these empirical results.

Humans↗
PubMed2005

[The ambivalence of love: from physiologic need to disease of the soul and of the body].

In this writing we intend to examine the Epicurean notion of love as Lucretius presents it, both in the light of the perspective open by Jackie Pigeaud in an article on the erotic dream in antiquity and in a comparision with the Stoic view. We will notice the curious relationship there is between Lucretius' notion of simulacra and Stoic conception of phantasiai, but also the fundamental difference there is in their respective perception with what follows concerning the responsibility of the individual in his action. A passage of Seneca will show us that man can be morally corrupted to such an extent as to be able to shape up by himself negative phantasiai. But the portrait we will try to make of Epicurean and Stoic theory of love will give us the opportunity to see its integration into the medical thought of Roman imperial age. The attention of the most eminent physicians of I-II century to the pathological issues both for the soul and for the body of an excessive erotic life, indeed, not only depends on the heritage of Aristotelian acquisitions in the field of biology and psychology, but also presents some interesting links with Epicurean and Stoic theory of love, coherently with the pretension of some of these physicians to become the tutors of both physic and moral health of humanity.

Greek World↗
PubMed2005

[Searching for rest in one's soul: the experience of mental health complaints in older Moroccan immigrants].

The number of Moroccan elderly in the Netherlands is growing. Although many have mental health problems, the mental health services have difficulties in reaching them. This study reports on the experience of mental health problems of elderly Moroccan migrants, their search for help and their view on the role of the mental health services. Twenty-two Moroccan elderly (11 men, 11 women) aged 55-75 were interviewed with a semi-structured questionnaire. From the interviews and observations it appeared that these elderly experience their health as bad. When asked, they deny mental health problems. Stress and dejection are not experienced as relating to mental health but as part of life associated with ageing, living in a foreign country, having physical, social and financial problems. The elderly feel that God sets them these tasks to overcome by themselves. Achieving rest in one's soul is central in this process. There is a taboo on serious mental health problems and people are ashamed of them. Only people who neglect religious prescriptions can to be affected by mental health problems. The elderly Moroccans hardly consult mental health services for these problems because then it would become clear that they cannot overcome their problems by themselves. Furthermore, the mental health services are unknown. Therefore, those services have to pay attention to the specific experience of mental complaints of elderly Moroccans. By offering psycho-education the mental health services may come within reach of those elderly.

Aged↗
PubMed1979

Changes in the fibroblastoid colony forming unit population from mouse bone marrow in early stages of Soule virus induced murine leukemia.

Fibroblastoid cells from mouse bone marrow belong to the hemopoietic inductive microenvironment involved in the regulation of hemopoiesis (1). We observed a decline in the incidence of precursors of these cells (fibroblastoid colony forming units) in the early stages of viral leukemogenesis. This was not accompanied by similar changes in bone marrow derived hemopoietic colony forming cell populations (CFU-s and CFU-c). Cultured fibroblastoid colonies from the bone marrow of young AKR mice or Soule murine leukemia virus inoculated BALB/c mice were found to produce type-C ecotropic virus. No such production was observed when similarly cultured granulocyte macrophage colonies (CFU-c) from the bone marrow of these mice were examined. The possibility that the fibroblastoid cell population is a major source of ecotropic leukemia viruses in the early stages of viral leukemogenesis is discussed.

Age Factors↗
PubMed1994

Memorial stones for the souls of animals killed for human welfare in Japan.

In Japan, at the old ports of the whaling industry, at all 365 slaughterhouses of the country, at some of the more than 90 wholesale markets of marine products, and at most of the about 170 testing facilities using laboratory animals, there are memorial stones for the souls of the animals killed for human welfare. Except at the whaling ports, where the memorials often can be dated back to the 17. century, all stones have been erected in the 20. century, most of them during the last 2 decades. The roots of this Japanese folk custom are probably in the prehistoric times of Shintoism. With the introduction of Buddhism in the 6. century, the killing of animals was considered sinful. Following the opening of the country in 1860, slaughterhouses were established.

Abattoirs↗
PubMed2005

Depression and medication adherence in outpatients with coronary heart disease: findings from the Heart and Soul Study.

BACKGROUND: Depression leads to adverse outcomes in patients with coronary heart disease (CHD). Medication nonadherence is a potential mechanism for the increased risk of CHD events associated with depression, but it is not known whether depression is associated with medication nonadherence in outpatients with stable CHD. METHODS: We examined the association between current major depression (assessed using the Diagnostic Interview Schedule) and self-reported medication adherence in a cross-sectional study of 940 outpatients with stable CHD. RESULTS: A total of 204 participants (22%) had major depression. Twenty-eight (14%) of 204 depressed participants reported not taking their medications as prescribed compared with 40 (5%) of 736 nondepressed participants (odds ratio [OR], 2.8; 95% confidence interval [CI], 1.7-4.7; P<.001). Twice as many depressed participants as nondepressed participants (18% vs 9%) reported forgetting to take their medications (OR, 2.4; 95% CI, 1.6-3.8; P<.001). Nine percent of depressed participants and 4% of nondepressed participants reported deciding to skip their medications (OR, 2.2; 95% CI, 1.2-4.2; P = .01). The relationship between depression and nonadherence persisted after adjustment for potential confounding variables, including age, ethnicity, education, social support, and measures of cardiac disease severity (OR, 2.2; 95% CI, 1.2-3.9; P = .009 for not taking medications as prescribed). CONCLUSIONS: Depression is associated with medication nonadherence in outpatients with CHD. Medication nonadherence may contribute to adverse cardiovascular outcomes in depressed patients.

Aged↗
PubMed2005

Depression and heart rate variability in patients with stable coronary heart disease: findings from the Heart and Soul Study.

CONTEXT: Depression is associated with low heart rate variability (HRV) in patients following myocardial infarction, suggesting that alterations in the autonomic nervous system may contribute to the adverse cardiac outcomes associated with depression. Whether depression is associated with low HRV in patients with stable coronary heart disease (CHD) is not known. OBJECTIVE: To examine the association between major depression and 24-hour HRV in patients with stable CHD. DESIGN, SETTING, AND PARTICIPANTS: Cross-sectional study of 873 outpatients with stable CHD recruited from outpatient clinics in the San Francisco Bay Area, California. MAIN OUTCOME MEASURES: Major depression was assessed using the Computerized National Institute of Mental Health Diagnostic Interview Schedule. Heart rate variability was measured by 24-hour ambulatory electrocardiography. RESULTS: A total of 195 participants (22%) had major depression. Overall, we observed no association between depression and HRV as measured by time domain or frequency domain variables. Mean HRV was similar in participants with and without depression (all P values >.10), and participants with depression were no more likely than those without depression to have low HRV (all P values >.10). CONCLUSIONS: We found no evidence of an association between depression and HRV in 873 outpatients with stable CHD. These findings raise questions about the potential role of HRV in the association between depression and cardiovascular disease.

Aged↗
PubMed2003

Depressive symptoms and health-related quality of life: the Heart and Soul Study.

CONTEXT: Little is known regarding the extent to which patient-reported health status, including symptom burden, physical limitation, and quality of life, is determined by psychosocial vs physiological factors among patients with chronic disease. OBJECTIVE: To compare the contributions of depressive symptoms and measures of cardiac function to the health status of patients with coronary artery disease. DESIGN, SETTING, AND PARTICIPANTS: Cross-sectional study of 1024 adults with stable coronary artery disease recruited from outpatient clinics in the San Francisco Bay Area between September 2000 and December 2002. Main Measures Measurement of depressive symptoms using the Patient Health Questionnaire (PHQ); assessment of cardiac function by measuring left ventricular ejection fraction on echocardiography, exercise capacity on treadmill testing, and ischemia on stress echocardiography; and measurement of a range of health status outcomes, including symptom burden, physical limitation, and quality of life, using the Seattle Angina Questionnaire. Participants were also asked to rate their overall health as excellent, very good, good, fair, or poor. RESULTS: Of the 1024 participants, 201 (20%) had depressive symptoms (PHQ score > or =10). Participants with depressive symptoms were more likely than those without depressive symptoms to report at least mild symptom burden (60% vs 33%; P<.001), mild physical limitation (73% vs 40%; P<.001), mildly diminished quality of life (67% vs 31%; P<.001), and fair or poor overall health (66% vs 30%; P<.001). In multivariate analyses adjusting for measures of cardiac function and other patient characteristics, depressive symptoms were strongly associated with greater symptom burden (odds ratio [OR], 1.8; 95% confidence interval [CI], 1.3-2.7; P =.002), greater physical limitation (OR, 3.1; 95% CI, 2.1-4.6; P<.001), worse quality of life (OR, 3.1; 95% CI, 2.2-4.6; P<.001), and worse overall health (OR, 2.0; 95% CI, 1.3-2.9; P<.001). Although decreased exercise capacity was associated with worse health status, left ventricular ejection fraction and ischemia were not. CONCLUSIONS: Among patients with coronary disease, depressive symptoms are strongly associated with patient-reported health status, including symptom burden, physical limitation, quality of life, and overall health. Conversely, 2 traditional measures of cardiac function-ejection fraction and ischemia-are not. Efforts to improve health status should include assessment and treatment of depressive symptoms.

Adult↗
PubMed2005

Anatomy of the soul as reflected in the cerebral hemispheres: neural circuits underlying voluntary control of basic motivated behaviors.

Understanding the principles of cerebral hemisphere neural network organization is essential for understanding the biological foundations of cognition and affect-thinking and feeling. A tripartite model of cerebral structure-function organization is reviewed, with attention focused on a behavior control system differentiation that mediates voluntary influences on three fundamental classes of goal-oriented behavior common to all animals. The model postulates just three cerebral divisions, one cortical and two nuclear (lateral or striatal, and medial or pallidal), that together generate a triple descending projection to the brainstem/cord motor system. This minimal circuit element is topographically organized and regionally differentiated, with the map of cortical areas serving as a basic starting point. Virtually all of the cerebral hemisphere projects on the upper brainstem behavior control column, atop the motor system hierarchy. The latter's rostral segment helps control ingestive (eating and drinking), defensive (fight or flight), and reproductive (sexual and parental) motivated behaviors, whereas its caudal segment helps control foraging or exploratory behavior to obtain or avoid specific goal objects associated with all classes of motivated behavior.

Animals↗
PubMed2005

Micturition and the soul.

There is a close connection between micturition and emotion. Several species use micturition to signal important messages as territorial demarcation and sexual attraction. For this reason, micturition is coordinated not in the spinal cord but in the brainstem, where it is closely connected with the limbic system. In cat, bladder afferents terminate in a cell group in the lateral dorsal horn and lateral part of the intermediate zone. Neurons in this cell group project to supraspinal levels, not to the thalamus but to the central periaqueductal gray (PAG). Neurons in the lateral PAG, not receiving direct sacral cord afferents, project to the pontine micturition center (PMC). The PMC projects directly to the parasympathetic bladder motoneurons and to sacral GABA-ergic and glycinergic premotor interneurons that inhibit motoneurons in Onuf's nucleus innervating the external striated bladder sphincter. Thus, PMC stimulation causes bladder contraction and bladder sphincter relaxation, i.e., complete micturition. Other than the PAG, only the preoptic area and a cell group in the caudal hypothalamus project directly to the PMC. The ventromedial upper medullary tegmentum also sends projections to the PMC, but they are diffuse and also involve structures that adjoin the PMC. Neuroimaging studies in humans suggest that the systems controlling micturition in cat and human are very similar. It seems that the many structures in the brain that are known to influence micturition use the PAG as relay to the PMC. This basic organization has to be kept in mind in the fight against overactive bladder (OAB) and urge-incontinence.

Animals↗