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At least 91 records · Page 5Linked to original sources

Current smoking and the risk of non-fatal myocardial infarction in the WHO MONICA Project populations.

BACKGROUND: Cohort studies have shown that smoking has a substantial influence on coronary heart disease mortality in young people. Population based data on non-fatal events have been sparse, however. OBJECTIVE: To study the impact of smoking on the risk of non-fatal acute myocardial infarction (MI) in young middle age people. METHODS: From 1985 to 1994 all non-fatal MI events in the age group 35-64 were registered in men and women in the WHO MONICA (multinational monitoring of trends and determinants in cardiovascular disease) project populations (18,762 events in men and 4047 in women from 32 populations from 21 countries). In the same populations and age groups 65,741 men and 66,717 women participated in the surveys of risk factors (overall response rate 72%). The relative risk of non-fatal MI for current smokers was compared with non-smokers, by sex and five year age group. RESULTS: The prevalence of smoking in people aged 35-39 years who experienced non-fatal MI events was 81% in men and 77% in women. It declined with increasing age to 45% in men aged 60-64 years and 36% in women, respectively. In the 35-39 years age group the relative risk of non-fatal MI for smokers was 4.9 (95% confidence interval (CI) 3.9 to 6.1) in men and 5.3 (95% CI 3.2 to 8.7) in women, and the population attributable fractions were 65% and 55%, respectively. CONCLUSIONS: During the study period more than half of the non-fatal MIs occurring in young middle age people can be attributed to smoking.

Adult↗

The use of new model life tables at very low mortality in population projections.

"New model life tables have been calculated...modifying the regional model life tables by Coale, Demeny and Vaughan published in 1983.... The purpose of the present article is not to repeat the description of the construction of the tables but to provide a systematic procedure for their use in projecting mortality into the future in low-mortality populations. The new model life tables incorporate age patterns of mortality that conform quite closely to the patterns in the lowest mortality populations yet on record and present extrapolated schedules that include systematic extensions of recent changes in age-specific mortality rates."

Age Factors↗

[Population projection for the Czech Republic, 1995-2020].

"In Autumn 1995 the Czech Statistical Office published the new population prognosis until the year 2020.... The change of population climate connected with the over-all change of economic and social conditions in the process of social transformation appears to be profound and fundamental. It is therefore unlikely that there would occur a turn in the near future and that...natality would grow...again to a...significant extent." (SUMMARY IN ENG)

Czech Republic↗

An evaluation of population projections by age.

A number of studies have evaluated the accuracy of projections of the size of the total population, but few have considered the accuracy of projections by age group. For many purposes, however, the relevant variable is the population of a particular age group, rather than the population as a whole. We investigated the precision and bias of a variety of age-group projections at the national and state levels in the United States and for counties in Florida. We also compared the accuracy of state and county projections that were derived from full-blown applications of the cohort-component method with the accuracy of projections that were derived from a simpler, less data-intensive version of the method. We found that age-group error patterns are different for national projections than for subnational projections; that errors are substantially larger for some age groups than for others; that differences in errors among age groups decline as the projection horizon becomes longer; and that differences in methodological complexity have no consistent impact on the precision and bias of age-group projections.

Adolescent↗

Estimation of contribution of changes in coronary care to improving survival, event rates, and coronary heart disease mortality across the WHO MONICA Project populations.

BACKGROUND: The revolution in coronary care in the mid-1980s to mid-1990s corresponded with monitoring of coronary heart disease (CHD) in 31 populations of the WHO MONICA Project. We studied the impact of this revolution on coronary endpoints. METHODS: Case fatality, coronary-event rates, and CHD mortality were monitored in men and women aged 35-64 years in two separate 3-4-year periods. In each period, we recorded percentage use of eight treatments: coronary-artery reperfusion before, thrombolytics during, and beta-blockers, antiplatelet drugs, and angiotensin-converting-enzyme (ACE) inhibitors before and during non-fatal myocardial infarction. Values were averaged to produce treatment scores. We correlated changes across populations, and regressed changes in coronary endpoints on changes in treatment scores. FINDINGS: Treatment changes correlated positively with each other but inversely with change in coronary endpoints. By regression, for the common average treatment change of 20, case fatality fell by 19% (95% CI 12-26) in men and 16% (5-27) in women; coronary-event rates fell by 25% (16-35) and 23% (7-39); and CHD mortality rates fell by 42% (31-53) and 34% (17-50). The regression model explained an estimated 61% and 41% of variance for men and women in trends for case fatality, 52% and 30% for coronary-event rates, and 72% and 56% for CHD mortality. INTERPRETATION: Changes in coronary care and secondary prevention were strongly linked with declining coronary endpoints. Scores and benefits followed a geographical east-to-west gradient. The apparent effects of the treatment might be exaggerated by other changes in economically successful populations, so their specificity needs further assessment.

Adult↗

Projected population effects of a nutritional blood pressure intervention on death rates from cardiovascular disease.

Evidence is accumulating that blood pressure can be modified by dietary changes. To test whether dietary manipulation could have an important effect on CVD death rates in a population, we used the logistic risk function to project the effects of pharmacological and dietary intervention. Successful pharmacological control of 60%, 80%, and 100% of the population with diastolic blood pressure values of 90 mm Hg or more is projected to result in 11%, 14%, and 18% reductions in CVD death rates, respectively. Reducing dietary fat to 23% and increasing the P/S ratio to 0.98 is projected to result in a 47% reduction in CVD death rates. The dietary intervention is projected to reduce the population requiring medication by 50% and reduce costs of hypertension treatment by 30%. On the basis of these projections, we conclude that dietary interventions for hypertension control can have an important effect both on death rates and treatment costs.

Adult↗

Health system implications of projected population trends for New Zealand 1978--2011.

Recent and projected demographic trends are reviewed and implications drawn for the health care system. Population per active doctor declines and both the total population and labour force age. This points to longterm change in the mix of health demands to be met, and raises socio-medical issues already the subject of public debate, for instance community versus institutional care of the elderly, ethical issues surrounding the prolongation of human life, and the cost of providing health care.

Adolescent↗