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PubMed1991

[Helium-neon laser in the complex treatment of patients with pulmonary tuberculosis].

The paper gives the results of helium-neon laser irradiation of the endobronchus used in the combined treatment of 30 patients with newly-diagnosed pulmonary tuberculosis complicated by nonspecific endobronchitis. Inclusion of endobronchial phototherapy and helium-neon laser radiation in the complex treatment of patients with newly diagnosed pulmonary tuberculosis complicated by nonspecific endobronchitis makes it possible to achieve clinical cure of an inflammatory bronchial process by 35% more frequently and over 2-3 times more rapidly than in its absence and to increase treatment efficiency of the main process; the terms of bacillary excretion decrease by 1 month, on the average, closure of destruction cavities (with an increase in the parameter by 17%) by 1.2 months and hospital treatment by 1.2 months, as compared with the respective parameters obtained by the traditional treatment of the similar patients.

Antitubercular Agents↗
PubMed1990

[Dynamics of morphological changes in the epithelial layer of the respiratory tract after endobronchial treatment of suppurative endobronchitis by helium-neon laser irradiation (experimental study)].

The results of a dynamic examination with the use of an electron microscope of semi- and ultrathin sections of the epithelial lining of the respiratory tract in the experimental dogs under endobronchial treatment of nonspecific endobronchitis with varying doses of low-energy radiation from helium-neon laser are presented. It was proved that the outcomes of regeneration of the bronchial mucosal membrane epithelium under endobronchial treatment of purulent endobronchitis with low-energy radiation of the helium-neon laser much depend both on exposure time (single doses of energy), and multiplicity (cumulative dose of energy), and the period after the laser therapy. The most favourable regeneration takes place under 5-minute (single dose of 4.5 J) radiation with 8 to 9 sessions (cumulative dose of 23.1 +/- 1.5 J). A regeneration most close to the normal condition of the bronchial mucous membrane epithelium is achieved at 2.5-3d months after the onset of the experiment (or a month after the laser therapy).

Animals↗
PubMed1990

The fragmentation of 670A MeV neon-20 as a function of depth in water. II. One-generation transport theory.

The results of an experiment to study the interaction of a beam of 670A MeV neon ions incident on a water column set to different thicknesses were compared with a "first principles" transport calculation in the straight-ahead approximation. This calculation assumes that the nuclear interactions of the incident particles lead to a secondary particle with the velocity of the incident projectile at the interaction point moving in the direction of the incident projectile. Subsequent nuclear interactions of the fragments were taken into account partially, by calculating the nuclear attenuation of the fragments in the residual material, but were not taken into account as a source of further nuclear interaction products. Fluence spectra were calculated per unit incident neon fluence for 14 absorber thicknesses. The acceptance for each fragment was calculated based on a knowledge of the material in the beam and of the beam extraction energy. The theoretical spectra were multiplied by the calculated acceptance and convoluted with the LET resolution associated with the experiment. The stopping power used in the transport calculation was found to predict a range approximately 1.6% shorter than that given by experiment; this small difference resulted in significant discrepancies between theory and experiment in the stopping region. For particles not stopping in the absorber, the transport calculation was accurate to within 30% for depths less than approximately 15 cm; the effects of tertiary particles become significant at greater depth.

Energy Transfer↗
PubMed1985

Primary and secondary radiation doses from neon beam fragments.

The neon beam at 250 MeV/nucleon from the Bevalac at the Lawrence Berkeley Laboratory is bombarded in nuclear emulsion. The experimental interaction cross section of the neon beam in emulsion is 1078 +/- 35 mb, in agreement with the calculations from the modified Bradt and Peters formula. The secondary fragments were identified and their partial production cross sections were calculated. From the fluences of the primary and secondary fragments, we determine their radiation doses which are presented as a function of depth in the absorber.

Ions↗
PubMed1993

The fragmentation of 670A MeV neon-20 as a function of depth in water. III. Analytical multigeneration transport theory.

This is the final report of a detailed study of the interaction of 670A MeV neon ions with water, used as a presumed tissue-equivalent target. A first comparison of the data with theoretical fluence spectra predicted by the one-generation heavy-ion transport code HZESEC was reported previously. In the present article, subsequent nuclear interactions of the fragment are taken into account, using the LBLBEAM multigeneration heavy-ion transport code, which incorporated new features and modifications intended to address some of the approximations made in the previous calculation. The LBLBEAM code uses the method of characteristics and an iterative procedure to solve a one-dimensional Boltzmann transport equation for the first through third successive generations of nuclear reaction products; it includes a recent version of the semiempirical model used to derive nuclear interaction cross sections. The stopping power used for the theory was calculated in the same way that experimental time-of-flight and energy-loss data are converted to obtain a comparison independent of stopping power; accordingly, good agreement was found between calculated and measured neon fluence spectra in the Bragg peak region. Multiple scattering effects were considered separately for each isotope in the present work. Acceptance factors were calculated as previously, assuming that all projectile fragments originate from the first nuclear interaction. The results show that lower-mass isotopes can account for the high-LET portions of the spectrum in measured fluence spectra. Third-generation products become increasingly important as a source of lighter fragments for depths comparable with the primary particle mean free path, accounting for between one-third and one-half of carbon and lighter particles near the Bragg peak; higher-order interactions were negligible for the detector geometry and material thicknesses examined. Agreement between measured and calculated fluence spectra is 30% (20% for integral fluences). Inclusion of hydrogen, helium, and lithium fragments improves agreement between calculated and measured RBE values for spermatogonial cell survival, but tertiary particle acceptance and track structure effects need to be understood in greater detail to predict RBE accurately.

Energy Transfer↗
PubMed1997

Helium-neon laser irradiation at fluences of 1, 2, and 4 J/cm2 failed to accelerate wound healing as assessed by both wound contracture rate and tensile strength.

BACKGROUND AND OBJECTIVE: Reports in the literature indicate that low energy laser irradiation has a biostimulatory effect on wound healing; however, no mechanism of this effect has been elucidated. STUDY DESIGN/MATERIALS AND METHODS: We attempted to establish a model from which to study the mechanism of biostimulation. The effects of low energy helium-neon irradiation on wound healing were observed in two rat models. In the first model, 1.5 cm diameter full thickness excisional skin defects were created in the dorsal midline of rats (n = 32). All animals were anesthetized and all eschars were debrided daily. Wound area was determined by caliper measurements for 2 weeks postoperatively. Rats that received a treatment of 1 J/cm2 had two defects in the dorsal skin. One wound was treated and the second was used as its own control. These measurements were not blinded. Rats that received 2 J/cm2, 4 J/cm2, or anesthesia alone had one defect on the dorsal skin. Caliper measurements of these wounds were blinded. We were unable to demonstrate any difference in the rate of wound contracture in rats that received a daily dose of 1 J/cm2, 2 J/cm2, 4 J/cm2, or anesthesia alone (P > 0.8 by student's t-test). In the second model, a single 2 cm longitudinal full thickness skin incision was created in the dorsal midline of each rat (n = 24). No difference was found between rats that received anesthesia alone and those treated daily with 2 J/cm2 as assessed by tensile strength measurements on postoperative days 7 and 14 (P > 0.8 by student's t-test between groups at both time points). These determinations were blinded. RESULTS: Despite our intentions of studying the mechanism of low energy HeNe biostimulation, we were unable to demonstrate a beneficial effect. CONCLUSION: In this study, helium-neon laser irradiation produced no measurable benefit on wound healing.

Animals↗
PubMed1992

Effect of helium-neon laser irradiation on serum lipid peroxide concentrations in burnt mice.

The effect of helium-neon irradiation on serum lipid peroxide concentrations in mice following 6-7% body surface area burns was investigated in a controlled study. Immediately following injury by an 8-sec 100 degrees C scalding, 25 mice were irradiated by a helium-neon laser at 0.05 J/cm2. A control group of the same size underwent identical treatment but received only sham irradiation. Serum lipid peroxide concentrations increased markedly in the control group at 0.5-4 h (P less than 0.0001, two sample t-test). In the laser treated group, the lipid peroxide concentrations remained relatively constant and were significantly depressed relative to the control group 4 h following burning (P less than 0.0001, two-sample t-test).

Animals↗
PubMed1995

A closer look at the dependence of neon colour spreading on wavelength and illuminance.

Ejima, Redies, Takahashi and Akita [(1984) Vision Research, 24, 1719-1726], studying the dependence of the neon colour spreading effect on wavelength and illuminance, found a number of relationships that appeared of difficult interpretation. This paper shows that these relationships can all be logically predicted within Grossberg and Mingolla's [(1985) Psychological Review, 92, 173-211] approach to the neon spreading problem, with no need of making ad hoc assumptions.

Color Perception↗
PubMed2006

Reactions of laser-ablated zinc and cadmium atoms with CO: infrared spectra of the Zn(CO)x (x = 1-3), CdCO-, and Cd(CO)2 molecules in solid neon.

Reactions of laser-ablated zinc and cadmium atoms with carbon monoxide molecules in solid neon have been investigated using matrix-isolation infrared spectroscopy. Based on the isotopic substitution, absorptions at 1852.2, 1901.9, 1945.9, and 1995.2 cm(-1) are assigned to the C-O stretching vibrations of the ZnCO, Zn(CO)(2), and Zn(CO)(3) molecules. Absorptions at 1735.8, 1961.3, and 2035.7 cm(-1) are assigned to the C-O stretching vibrations of the CdCO(-) and Cd(CO)(2) molecules. In contrast with the previous argon experiments, more species and more valuable information about the reaction of zinc and cadmium atoms with CO have been obtained in solid neon. Density functional theory calculations have been performed on these zinc and cadmium carbonyls. The agreement between the experimental and calculated vibrational frequencies, relative absorption intensities, and isotopic shifts substantiates the identification of these carbonyls from the matrix infrared spectrum. The present experiments also reveal that zinc is more reactive with CO than cadmium.

Journal Article↗
PubMed1989

Functional theory of illusory conjunctions and neon colors.

Illusory conjunctions are the incorrect perceptual combination of briefly presented colors and shapes. In the neon colors illusion, achromatic figures take on the color of an overlaid grid of colored lines. Both illusions are explained by a theory that assumes (a) poor location information or poor spatial resolution for some aspects of visual information and (b) that the spatial location of features is constrained by perceptual organization. Computer simulations demonstrate that the mechanisms suggested by the theory are useful in veridical perception and they are sufficient to produce illusory conjunctions. The theory suggests mechanisms that economically encode visual information in a way that filters noise and fills in missing data. Issues related to neural implementation are discussed. Four experiments illustrate the theory. Illusory conjunctions are shown to be affected by objective stimulus organization, by subjective organization, and by the linguistic structure of ambiguous Hebrew words. Neon colors are constrained by linguistic structure in the same way as illusory conjunctions.

Adolescent↗
PubMed2005

The 'solar model problem' solved by the abundance of neon in nearby stars.

The interior structure of the Sun can be studied with great accuracy using observations of its oscillations, similar to seismology of the Earth. Precise agreement between helioseismological measurements and predictions of theoretical solar models has been a triumph of modern astrophysics. A recent downward revision by 25-35 per cent of the solar abundances of light elements such as C, N, O and Ne (ref. 2) has, however, broken this accordance: models adopting the new abundances incorrectly predict the depth of the convection zone, the depth profiles of sound speed and density, and the helium abundance. The discrepancies are far beyond the uncertainties in either the data or the model predictions. Here we report neon-to-oxygen ratios measured in a sample of nearby solar-like stars, using their X-ray spectra. The abundance ratios are all very similar and substantially larger than the recently revised solar value. The neon abundance in the Sun is quite poorly determined. If the Ne/O abundance in these stars is adopted for the Sun, the models are brought back into agreement with helioseismology measurements.

Journal Article↗
PubMed2004

Rovibrational and dynamical properties of the hydrogen bonded complex (CH2)2S-HF: a combined free jet, cell, and neon matrix-Fourier transform infrared study.

Fourier transform infrared spectra of the nu(s) (HF stretching) band of the (CH(2))(2)S-HF complex have been recorded at 0.1-0.5 cm(-1) resolution in a cooled cell, in a supersonic jet expansion seeded with argon and in a neon matrix at 4.5 K. The combination of controlled temperature effects over a range of 40-250 K and a sophisticated band contour simulation program allows the separation of homogeneous and inhomogeneous contributions and reveals significant anharmonic couplings between intramolecular and intermolecular vibrational modes similar to our previous work on (CH(2))(2)S-DF. The sign of the coupling constants is consistent with the expected strengthening of the hydrogen bond upon vibrational excitation of HF which also explains the observed small variations of the geometrical parameters in the excited state. The analysis of sum and difference combination bands involving nu(s) provides accurate values of intermolecular harmonic frequencies and anharmonicities and a good estimate of the dissociation energy of the complex. Frequencies and coupling parameters derived from gas phase spectra compare well with results from neon matrix experiments. The effective linewidth provides a lower bound for the predissociation lifetime of 10 ps. The comparison between effective linewidths and vibrational densities of states for (CH(2))(2)S-HF and -DF complexes highlights the important role of intramolecular vibrational redistribution in the vibrational dynamics of medium strength hydrogen bonds.

Journal Article↗
PubMed2004

Computation of the properties of liquid neon, methane, and gas helium at low temperature by the Feynman-Hibbs approach.

The properties of liquid methane, liquid neon, and gas helium are calculated at low temperatures over a large range of pressure from the classical molecular-dynamics simulations. The molecular interactions are represented by the Lennard-Jones pair potentials supplemented by quantum corrections following the Feynman-Hibbs approach. The equations of state, diffusion, and shear viscosity coefficients are determined for neon at 45 K, helium at 80 K, and methane at 110 K. A comparison is made with the existing experimental data and for thermodynamical quantities, with results computed from quantum numerical simulations when they are available. The theoretical variation of the viscosity coefficient with pressure is in good agreement with the experimental data when the quantum corrections are taken into account, thus reducing considerably the 60% discrepancy between the simulations and experiments in the absence of these corrections.

Journal Article↗
PubMed2005

Infrared spectra of NH2NO, NH2NO+, and NNOH+ and of the N2...H2O complex trapped in solid neon.

When a Ne:H2:N2O mixture is co-deposited at 4.3 K with a beam of neon atoms that have been excited in a microwave discharge, NH2NO+ is stabilized in sufficient concentration for detection of five of its vibrational fundamentals. Their assignments are supported by isotopic substitution studies and by the results of unrestricted B3LYP/cc-pVTZ calculations. Electron recombination results in the stabilization of NH2NO, for which the previously reported argon-matrix assignments are confirmed and extended. The OH-stretching fundamental of NNOH+ also is present in the spectrum of the initial sample deposit, but because of proton sharing with the neon matrix is shifted 43.3 cm(-1) from the gas-phase band center. The OD-stretching fundamental of NNOD+ is identified for the first time in the present study. An absorption at 2311.1 cm(-1) is contributed by the NN-stretching vibration of a complex of N2, probably with an ionic species. On prolonged visible and near-ultraviolet irradiation of the deposit, absorptions of the binary N2...H2O complex become increasingly prominent.

Journal Article↗
PubMed2006

Rovibrational spectroscopy calculations of neon dimer using a phase space truncated Weyl-Heisenberg wavelet basis.

In a series of earlier articles [B. Poirier J. Theor. Comput. Chem. 2, 65 (2003); B. Poirier and A. Salam J. Chem. Phys. 121, 1690 (2004); B. Poirier and A. Salam J. Chem. Phys. 121, 1740 (2004)], a new method was introduced for performing exact quantum dynamics calculations in a manner that formally defeats exponential scaling with system dimensionality. The method combines an optimally localized, orthogonal Weyl-Heisenberg wavelet basis set with a simple phase space truncation scheme, and has already been applied to model systems up to 17 degrees of freedom (DOF's). In this paper, the approach is applied for the first time to a real molecular system (neon dimer), necessitating the development of an efficient numerical scheme for representing arbitrary potential energy functions in the wavelet representation. All bound rovibrational energy levels of neon dimer are computed, using both one DOF radial coordinate calculations and a three DOF Cartesian coordinate calculation. Even at such low dimensionalities, the approach is found to be competitive with another state-of-the-art method applied to the same system [J. Montgomery and B. Poirier J. Chem. Phys. 119, 6609 (2003)].

Journal Article↗
PubMed1994

Reaction times to neon, LED, and fast incandescent brake lamps.

Standard incandescent brake lamps have a relatively slow rise time. It takes approximately a quarter of a second for them to reach 90% of asymptotic light output, causing potential delays in responses by following drivers. The present study evaluated reaction times to brake signals from standard incandescent brake lamps and from three alternative brake lamps with substantially faster rise times: neon, LED, and fast incandescent. The study, performed in a laboratory, simulated a daytime driving condition. The subject's task was to respond as quickly as possible to the onset of either of two brake lamps in the visual periphery, while engaged in a central tracking task. Brake signals were presented at two levels of luminous intensity. The results showed that reaction times to the alternative brake lamps were faster than to the standard incandescent lamp, with the advantage averaging 166 ms for the LED and neon lamps, and 135 ms for the fast incandescent lamp. A reduction of the signals' luminous intensity from 42 cd to 5 cd increased the reaction time by 84 ms.

Adult↗
PubMed1990

Effect of helium-neon laser auriculotherapy on experimental pain threshold.

This study was conducted to examine the effects of helium-neon laser auriculotherapy on experimental pain threshold. Eighty healthy female and male subjects, aged 18 to 39 years, were assigned randomly to one of two treatment groups. Subjects in the Experimental Group (n = 41) received laser stimulation, and subjects in the Control Group (n = 39) received sham stimulation to appropriate acupuncture points on the left ear. Experimental pain threshold at the ipsilateral wrist was determined with an electrical stimulus immediately before and after treatment. The mean change (posttreatment minus pretreatment) for the Experimental Group was greater than the mean change for the Control Group (p less than .05). The Experimental Group demonstrated a statistically significant (p less than .05) increase in mean pain threshold after treatment, but the Control Group did not. Results indicate that helium-neon laser auriculotherapy can increase experimental pain threshold and suggest a possible alternative for patients intolerant of transcutaneous electrical nerve stimulation.

Adult↗
PubMed1999

Experimental and simulated neon spectra in the 10-nm wavelength region from tokamak and reversed field pinch plasmas.

Experimental neon spectra (in the 10-nm region), from the tokamak Tore Supra and the reversed field pinch experiment RFX, have been simulated. The spectra include lines from three neon ionization states, namely Ne(7+), Ne(6+), and Ne(5+) ions. Collisional radiative models have been built for these three Ne ions, considering electron collisional excitation and radiative decay as populating processes of the excited states. These models give photon emission coefficients for the emitted lines at electron density and temperature values corresponding to the experimental situations. Impurity modelling is performed using a one-dimensional impurity transport code, calculating the steady-state radial distribution of the Ne ions. The Ne line brightnesses are evaluated in a post-process subroutine and simulated spectra are obtained. The parts of the spectra corresponding to a single ionization state do not depend on the experimental conditions and show good agreement with the simulated single ionization state spectra. On the other hand, the superposition of the three spectra depends on the experimental conditions, as a consequence of the fact that the ion charge distribution depends not only on the radial profiles of the electron density and temperature, but also of the impurity transport coefficients. Simulations of the Ne spectra (including transport) give confidence in the atomic physics calculations; moreover, they allow the determination of the transport coefficients in the plasma region emitting the considered ionization states.

Journal Article↗