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At least 91 records · Page 5Linked to original sources

Isolation and characterization of a new ribosome inactivating protein, momorgrosvin, from seeds of the monk's fruit Momordica grosvenorii.

Momorgrosvin, a single-chained glycoprotein with a molecular weight of 27.7 kilodaltons and an isoelectric point of about 9 was isolated from the seeds of Momordica grosvenorii (Family Cucurbitaceae). The isolation procedure entailed acetone precipitation, affinity chromatography on Hi Trap Blue, cation exchange chromatography on Resource S and size exclusion chromatography on Superose 12. The sequence of the first eighteen N-terminal amino acid residues of momorgrosvin exhibited homology to those of RIPs from other Momordica species. Momorgrosvin inhibited protein synthesis in the rabbit reticulocyte lysate system with an IC50 of 0.3 nM and displayed RNA N-glycosidase activity giving rise to the diagnostic Endo's band at a concentration as low as 9 nM. The protein acted on tRNA to produce acid-soluble uv-absorbing species.

China↗

Bleeding monks.

Explore the source record for details and available documents.

Bloodletting↗

[1848: Gregor Mendel, the monk who wanted to be a citizen].

This article proposes a previously unpublished French translation of a petition, in German, addressed by six Augustinian friars to the Constitutional Parliament of Vienna in the revolutionary year 1848. The petition states that members of religious orders are deprived of civil rights and demands that they be given citizenship ; it also contains a bitter attack on the monastic institution. We suggest that Mendel was the author of this text, which he signed and actually hand-wrote.

Austria↗

Dr Monk's medical digest.

The Liber passionalis is an early and hitherto mostly unexplored example of a composite medical work on diagnosis and therapy, similar to the better-known compilations circulating under the titles Petroncellus and Gariopontus (Passionarius Galieni). It shows the efforts made to provide comprehensive coverage of morbid conditions drawn from a choice of the best sources available to the compiler, sources which in some instances complement or enhance our knowledge of ancient medicine in a way overlooked by specialists in the field for a long time and which provide the best clue when trying to assess medical expertise at the turn of the first millennium. The paper explores the transmission, structure and sources of the Liber passionalis, touching on the body of medical literature available in the early Middle Ages.

Books↗