Quantitative cytochemical investigations on NK/Ly mouse ascites tumour cells treated with Degranol. II. Fast green cytophotometric and interference microscopic investigations.
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Animals↗
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Results for “Mannomustine”
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Changes in the lipid composition of tumour and hepatic tissues of rats bearing Guerin carcinoma following treatment with the nitrogen mustard degranol.
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Animals↗
In vitro decomposition rate of degranol in sensitive and resistant NK/lymphoma ascites tumours.
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Animals↗
The analysis of changes in the activation energy of succinate dehdrogenase as influenced by some antitumour agents.
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Animals↗
Interaction with heparin of deoxyribonucleoprotein complex damaged in vivo by nitrogen mustards.
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Alkylation↗
Enhanced growth of transplanted tumours after treatment with cytotoxic agents.
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Animals↗
Observations on tumour cells in the circulating blood before and after chemotherapy.
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Animals↗
The role of the carrying molecule in the cross-resistance against sugar alcohol derivatives.
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Alcohols↗
Pharmaco-biochemical studies on cytotoxic polyol derivatives. II. The effect of biological alkylating agents on the thermal-denaturation properties of DNA.
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Alkylating Agents↗
Effect of various nucleic acid and protein synthesis inhibitors on anaphylactoid inflammation in rats.
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Anaphylaxis↗
Effect of various nucleic acid and protein synthesis inhibitors on the insulin-induced sensitization of anaphylactoid inflammation in rats.
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Anaphylaxis↗
Localization of chemically induced breaks in chromosomes of human leucocytes.
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Cells, Cultured↗
Clinical pharmacology of carbohydrate derivatives with cytostatic potency.
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Animals↗
Heterogeneity of tumour ribonucleic acid and the effect of 'degranol' on it.
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Mannitol↗
Effect of chemotherapeutics on the nucleic acid metabolism of tumours. Incorporation of 32P into nucleic acids following treatment with degranol.
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Mannomustine↗
Effect of some nitrogen mustards and thoracic duct drainage on lymphocyte distribution in rats.
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Animals↗
Mechanisms of spontaneous and induced heteroploidization and polyploidization.
Mechanisms of heteroploidization and polyploidization were studied in tissue cultures, using various methods and cell lines. In untreated populations cells with different chromosome number are formed by mitotic non-disjunction. Mononuclear polyploid cells are formed by repeated DNA synthesis (endoreduplication) and polynuclear giant cells by postmitotic fusion of the daughter cells. These phenomena occur more frequently in cell populations treated with cystostatic drugs. Most polyploid cells are not viable.
Animals↗
Experimental study of the combined effect of leukeran, degranol and predisolone.
The effect of the combined treatment with leukeran, degranol and prednisolone on the lymphoid tissue and marrow hamopoiesis in rats is studied. The simultaneous administration of these drugs is shown to cause a more effective inhibition of the lymphoid tissue and a less suppression of the marrow, as compared with their separate administration.
Animals↗