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The outcome of intestinal fistulae: the Louisiana State University Medical Center--Shreveport experience.

Fistulae arising from the intestinal tract are associated with significant morbidity and mortality rates. Most contemporary studies of fistulae report mortality rates between 6 and 20 per cent. The major causes of death in these patients are sepsis, electrolyte imbalance, and malnutrition. A total of 48 patients with either external or internal intestinal fistulae were reviewed in this study over a 5-year period at the Louisiana State University Medical Center at Shreveport. Intestinal fistulae were classified into three types, anatomic site, physiologic type, and etiology, to evaluate morbidity and mortality rates. We also attempted to evaluate the role of parenteral nutrition in this patient population, but our data were inconclusive because of the limited number of patients. There was no difference in mortality rates associated with anatomical sites. High-output fistulae were associated with a higher mortality rate compared to low-output fistulae. Fifty-six per cent of the patients achieved closure. The overall mortality rate was 21 per cent. Spontaneous closure rates were lower when compared to those in other studies. This was attributed to sepsis, malignancy, and history of previous radiation therapy. Management of intestinal fistulae includes control of sepsis, correction of electrolyte disturbances, nutritional support, and operative intervention if necessary.

Adolescent↗

[Obturation of external intestinal fistulas].

Under analysis is an experience with the application of well-known methods of obturation in the treatment of 176 patients with external intestinal fistulas. The effectiveness of the application of the well-known methods of obturation in non-formed intestinal fistulas was noted in three of ten patients, good results were obtained in five of ten patients with formed fistulas.

Adult↗

[Morphologic and functional aspects in the treatment of patients with intestinal fistulas].

Combination of severe purulent processes (peritonitis, phlegmons, and extensive wounds of the abdominal wall), eventration, and complete high unformed intestinal fistulas leads to rapid hemostasis disorders and emaciation. In nonoperative treatment lethality reaches 70%. Complete bilateral disconnection of the fistula bearing intestinal loop is the operation of choice in such situations. In this case the length of the disconnected intestinal segments may be two thirds of the length of the jejunum and the greater part of the colon. The results of morphofunctional study of an intestinal segment disconnected for a long period are analysed. The tactics of active surgical treatment is illustrated by clinical cases.

Adult↗

Perforated typhoid enteritis. The problem of intestinal fistula.

Typhoid enteritis with perforation is still a major problem in many hospital centres in the tropics and post-operative intestinal fistula accounts for much of the morbidity and mortality among those who survive the septicaemic phase of the disease. In poorly equipped hospitals with limited resources, early aggressive re-exploration to close the intestinal fistula when the patient is still strong is advocated in preference to conservative treatment which is prolonged, of uncertain outcome and liable to be abandoned especially where the patient is poor and unable to provide the material for fluid replacement and nutritional support over a long period of time.

Adolescent↗