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Facial injury and airway threat from inhalant abuse: a case report.

Fluorinated hydrocarbons cause toxicity in humans via their dysrhythmogenic potential and their local physical effects on the skin and mucous membranes. The former is generally the more life-threatening toxic consequence. We present a case of fluorinated hydrocarbon injury resulting from an intentional inhalation exposure that created facial frostbite, which threatened the patient's airway. The clinical range and management of these tissue-toxic effects are reviewed.

Adolescent↗

The search for cofactors in AIDS, including an analysis of the association of nitrite inhalant abuse and Kaposi's sarcoma.

The identification of cofactors in AIDS is a challenging scientific task. If successful, identifying cofactors could prove valuable in understanding the pathogenesis of HIV infection and AIDS and in the development of strategies to prolong survival and/or prevent complications in HIV-infected individuals. There is sufficient evidence to suggest the existence of a cofactor in KS in AIDS. Nitrite inhalants remain a leading candidate to be the KS cofactor. Until more is known to document or refute this specific virus-drug interaction hypothesis in the pathogenesis of KS in AIDS, clinicians should encourage their patients to avoid use of nitrite inhalants. This article was prepared by a Federal Government employee as part of official duties; therefore, the material is in the public domain and may be reproduced or copied without permission.

Acquired Immunodeficiency Syndrome↗

Medical complications due to mothball abuse.

Inhalant abuse is a major public health problem that has been associated with numerous acute and chronic medical problems. Inhalants are defined as volatile organic substances and are found in common household and commercial products that are easily accessible, inexpensive, and legally obtained. We discuss a rare case of mothball abuse predominantly by inhalation. The patient had acute peripheral neuropathy and chronic renal failure, both of which were concluded to be casually related to mothball abuse. We briefly review the abuse potential and medical complications of naphthalene and paradichlorobenzene, the compounds in mothballs. Our case illustrates that common household products not usually identified as recreational drugs can be abused; furthermore, linking specific medical problems with particular inhalants can be difficult because of confounding variables.

Chlorobenzenes↗

Inhalant abuse and heroin addiction: a comparative study on 574 opiate addicts with and without a history of sniffing.

In the present study, a comparison relating to various social aspects was made between 74 opiate addicts who had abused or continued to abuse solvents and 500 fixers without sniffing experience (SE). The results show clear differences between the two groups with reference to age, sex, social status, socialization conditions, family structure, education, vocational training, drug sequence and criminality as well as attitude and motivation towards withdrawal therapy. Contrary to hitherto existing assumptions, solvent abuse among children and juveniles can lead to opiate addiction, given a certain set of social circumstances. Polytoxicomanic opiate addicts with sniffing experience can be differentiated as a marginal group with particularly unfavorable developmental conditions and a specific course of addiction. The results make it clear that a stronger differentiation is necessary within the group of heroin addicts, which has often been regarded as being homogeneous.

Adolescent↗

Inhalant abuse.

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Acute Disease↗

Inhalant abuse.

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Adolescent↗