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[Experiences with transtrabecular iridectomy].

A transtrabecular iridectomy was performed in 17 eyes with narrow angle glaucoma, and in 3 eyes in which the trabecular meshwork was gonioscopically not visible. Postoperatively, the conjunctive lied directly on the sclera in 14 cases; in 6 cases a circumscribed conjunctival bleb developed in the operation field. After a follow-up of 12 or 24 months, the intraocular pressure was normalized without miotics in 15 of 17 eyes. The mechanism of transtrabecular iridectomy is discussed.

Follow-Up Studies↗

[The efficacy of Charleux's peripheral iridectomy].

The simplicity of Charleux's technique for peripheral iridectomy is underlined. In a lot of 15 eyes with acute angle closure glaucoma, the i.o.p. after surgery was under 21 mm Hg when the attack lasted less than 48 hours. In a second group of 20 eyes with occludable angle/congener eyes suffered attacks/peripheral iridectomy with Charleux's technique prevented acute angle closure/56 months of postoperative observation.

Acute Disease↗

[Argon laser peripheral iridoplasty and laser iridectomy for plateau iris glaucoma].

OBJECTIVE: To evaluate the therapeutic effects of a combined laser technique for plateau iris glaucoma. METHODS: 20 cases (37 eyes) of early plateau iris glaucoma were treated by a laser technique that included argon laser peripheral iridoplasty and argon + Nd:YAG laser iridectomy. RESULTS: The postoperative follow-up ranged from 8 months to 4 years and 7 months (30 eyes for more than 2 years, mean 2.7 years). 17 cases (32 eyes) obtained satisfactory effects, no acute-attacks were seen in the follow-up, intraocular pressure decreased from 5.8 +/- 1.04 kPa to below 2.74 kPa, peripheral anterior chamber depth increased, angle widened, the iris retracted away from the trabecular meshwork, thus further synechiae of chamber angle were prevented effectively, and the dark room provocative test results turned to negative in 86.7% of cases. CONCLUSION: Argon laser peripheral iridoplasty combined argon + Nd:YAG laser iridectomy may be a safe and effective method for treatment of plateau iris glaucoma.

Adult↗

Aqueous humor dynamics following total iridectomy in the cynomolgus monkey.

Twenty-two cynomolgus monkeys underwent unilateral total iridectomy in vivo. Several weeks to several months postoperatively, intraocular pressure (IOP) was determined bilaterally by manometry under pentobarbital anesthesia (15 monkeys), by a minified Goldmann applanation tonometer under CI-744 anesthesia (16 monkeys), and by a minified Draeger applanation tonometer under light phencyclidine catalepsia (4 monkeys). Mean IOP in aniridic eyes was about 0.3 mm Hg, or about 3%, lower than in opposite eyes. IOPs of aniridic and opposite eyes of the individual monkeys were highly correlated in all groups. In 11 monkeys, resting total outflow facility and the facility response to intravenous pilocarpine were determined 6 to 9 weeks postoperatively by two-level constant-pressure perfusion under pentobarbital anesthesia. There were no significant differences between mean resting facility, postpilocarpine facility, or facility response to pilocarpine of aniridic and opposite eyes. Resting facility, postpilocarpine facility, and facility response to pilocarpine in aniridic and opposite eyes of the individual monkeys were each highly correlated. Total iridectomy in the cynomolgus monkey apparently has little, if any, effect on IOP, outflow facility, or facility response to intravenous pilocarpine, and the iris plays little, if any, role in mediating the facility response to intravenous pilocarpine.

Anesthetics↗

Endophthalmitis after cataract surgery in eyes with small pupils managed by sector iridectomy and polypropylene suture closure.

Two patients with small pupils developed endophthalmitis following cataract surgery during which the small pupils were managed by sector iridectomy and closed with a polypropylene suture. Prior studies have reported that implantation of intraocular lenses (IOLs) with haptics made of polypropylene is associated with a higher risk of postoperative endophthalmitis than the use of IOLs with polymethylmethacrylate haptics. Endophthalmitis in the two patients reported herein was managed successfully without removal of the polypropylene suture; vision returned to 20/60 in one patient and 20/30 in the other patient. Iris retractors may represent a faster and safer alternative management option for small pupils than sector iridectomy closed with a polypropylene suture.

Aged↗

Laser iridectomy.

The argon laser and the ruby laser have been used to open the pigment layer in three cases of surgically incomplete peripheral iridectomy. The technique, its advantages and complications, were discussed. On two additional eyes, full-thickness argon laser iridectomy was unsuccessful.

Aged↗

Iridectomy in rubeosis iridis.

Creating an iridectomy in the face of rubeosis iridis carries a significant risk of hyphema. A technique is described utilizing a bipolar micro-cautery to cauterize iris vessels under direct observation before cutting iris tissue. This allows the iridectomy to be performed with less risk of intraocular bleeding.

Cautery↗

Iridectomy technique in trabeculectomy.

Peripheral iridectomy in trabeculectomy surgery should be larger than the scleral opening to prevent adherence of iris to the edges of the scleral opening. A method for the fashioning of such an iridectomy is described.

Glaucoma↗

Value of prophylactic peripheral iridectomy on the second eye in angle-closure glaucoma.

In a group of 250 patients with gonioscopically proved angle-closure glaucoma, 72 who did not have prophylactic peripheral iridectomy were reviewed and the adverse effects suffered by these patients were analysed. Comparison was made with 63 patients from the same group who did have peripheral iridectomy. All these patients were drawn from the Glaucoma Clinic, University Department of Ophthalmology, Manchester Royal Eye Hospital.

Adult↗

Corneal endothelial changes following short pulsed laser iridotomy and surgical iridectomy.

Pre- and post-operative endothelial specular photo-microscopy was performed on 46 eyes of 29 patients who had been randomly assigned to iridotomy with the Nd:YAG or the dye laser, or to surgical peripheral iridectomy for the relief of pupil block glaucoma. Localised damage to the endothelium was observed in two eyes following Nd:YAG laser iridotomy and in one eye following dye laser iridotomy. No endothelial changes were recognised after surgical peripheral iridectomy. Central corneal endothelial cell densities remained unchanged following all procedures.

Aged↗

Argon laser iridectomy.

By using a continuous wave argon laser, successful iridectomy was achieved in 41 out of 51 phakic eyes selected for the procedure. Three of the successful procedures required multiple sittings. The procedure was performed on an out-patient basis under topical anaesthesia, usually required less than one-half hour for completion with a negligible complication rate. Therefore, where available ArLI appears to present a viable alternative to surgical iridectomy for the definitive treatment of angle closure glaucoma.

Glaucoma↗

[Laser trabeculotomy and laser iridectomy. 3 Years' experience with the Glaucoma Research Laser (Britt) (author's transl)].

This report presents a 3-year study of treatment of the anterior portion of the eye with the Glaucom Research Laser, Model 152, made by Britt Corp. Los Angeles. This study deals specifically with laser trabeculotomy and iridectomy. In this period of time 176 eyes were treated with trabeculotomy and 60 with iridectomy. All types of glaucoma were represented. The technique and the results are demonstrated. This pulsed Argon laser permits surgery with a high rate of success without any serious complications.

Anesthesia↗

Delayed hyphema after argon laser iridectomy.

A 77-year-old black woman without neovascularization developed spontaneous hyphema two days after laser iridectomy. Bleeding originated at the site of iridectomy. This complication has not been previously reported.

Aged↗

Transcorneal peripheral iridectomy.

A surgical technique to perform transcorneal iridectomy is described. Its advantages over peripheral iridectomy with conjunctival flap and laser methods are discussed.

Glaucoma↗

Visual acuity after iridectomy or aspiration for congenital cataract: Experimental and clinical studies.

Studies with a camera and a model eye showed that the image produced by peripheral light rays is inferior to the image produced by paraxial rays. In a retrospective clinical study, we determined the best corrected visual acuity in 33 patients (52 eyes) who had had iridectomy (group I) or aspiration (group II) or both for central cataracts. Vision was significantly better (p less than 0.01) in group II than in group I, and postoperative complications of aspiration were minimal. Some patients had unilateral amblyopia or pendular nystagmus. We conclude that if vision is to be improved with a single procedure, aspiration - not optical iridectomy - is indicated. We could not identify any factors in early infancy that would have predicted which patients with congenital central cataracts required early surgery.

Cataract↗

[Iridectomy, an alternative in the treatment of total hyphema].

Iridectomy as a therapeutic alternative for total hyphema. Complete resorption of blood in eyes with posttraumatic total hyphema and high intraocular pressure not amenable to medical therapy was accomplished by means of peripheral iridectomy. No postoperative complications were noted in any of the six patients studied and intraocular pressure remained normal without medications for at least one year after the surgical procedure. Pupillary block and obstruction of the drainage pathway by the clot could account for the secondary glaucoma in these patients.

Adolescent↗

[Prevention of IOP rise following laser iridectomy with topical timolol and indomethacin].

Double-masked study on 40 eyes (40 patients) of primary angle-closure glaucoma demonstrated that topical timolol and indomethacin prevented the IOP rise following combined argon and Nd:YAG laser iridectomy. A combination of the 2 drugs was especially effective in that the number of patients who would have an IOP increase over 1.33 kPa (1 kPa = 7.5 mmHg) above the baseline was reduced by 80%. The mechanism of IOP rise following iridectomy and its prevention were discussed.

Female↗

Influence of peripheral iridectomy on intravitreous penetration of topical nipradilol.

PURPOSE: Penetration of drug from the anterior chamber to the vitreous is substantial in aphakic eyes, but negligible in normal phakic eyes. The purpose of this study is to investigate the effect of the presence of peripheral iridectomy (PI) which bypasses iris-lens diaphragm on the drug penetration from the anterior chamber to the vitreous. METHODS: Twelve Japanese White rabbits underwent PI in a randomly chosen eye and the same procedures except removal of the peripheral iris in the contralateral eye. Nine weeks after the procedure, topical instillation of 20 microl of 1% nipradilol into the both eyes was repeated three times at five-minute intervals, and two hours later the animals were sacrificed and the both eyes were enucleated. Concentrations of nipradilol in the aqueous and vitreous were determined using a high-performance liquid chromatography. RESULTS: The concentrations of nipradilol were significantly greater in the eyes with PI than those in the contralateral control eyes in the aqueous (5636 +/- 1688 vs 2835 +/- 663 ng/g, mean +/- standard error, n = 12, p = 0.0028) and in the anterior vitreous (11.9 +/- 2.5 vs 5.6 +/- 1.0 ng/g, p = 0.0047), while not in the posterior vitreous or in the posterior retina-choroid. The ratios of the nipradilol concentrations in the anterior or posterior vitreous to that in the aqueous were not significantly different between the both eyes. CONCLUSIONS: The presence of PI had little effect on the penetration of topically instilled nipradilol from the anterior chamber to vitreous.

Administration, Topical↗