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Results for “IODOHIPPURIC ACID”

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PubMed1987

Evaluation of the renal clearance of technetium-99m PAHIDA in dogs.

The renal clearance of the technetium-99m complex of para[(biscarboxylmethyl)-aminomethylcarboxyamino]hippuric acid ([99mTc]PAHIDA), has been previously studied in rodents and falls between that of [99mTc]DTPA (diethylenetriaminepentaacetic acid) and iodine-131 (131I) orthoiodohippuran (OIH). To investigate the effect of species variation, the plasma clearance of [99mTc]PAHIDA was investigated in dogs. The plasma disappearance of the renal agent approached that of [99mTc]DTPA and was significantly less than that of OIH. Despite the structural similarities of the PAHIDA ligand and aminohippurate, the [99mTc]PAHIDA complex undergoes little, if any, tubular secretion in the canine kidney.

Aminohippuric Acids↗
PubMed1965

MEASUREMENT OF THE FALL IN THE LEVEL OF PLASMA RADIOACTIVITY AFTER INTRAVENOUS ADMINISTRATION OF RADIOHIPPURAN AS A TEST OF RENAL FUNCTION.

The level of plasma radioactivity following a single intravenous injection of (131)I-labelled sodium orthoiodohippurate (radiohuppuran) falls with time in a tri-exponential fashion. The rate of fall of plasma radioactivity after an intravenous injection of radiohippuran was measured over the period 25 to 40 minutes from the time of injection and was expressed as the half-life of radiohippuran. The results suggest that this procedure may provide a valid measure of renal function which is more sensitive than the blood urea estimation but less sensitive than the creatinine clearance.

Blood Chemical Analysis↗