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Medicaid program; federal financial participation for inmates in public institutions and individuals in an institution for mental disease or tuberculosis--Health Care Financing Administration. Proposed rule.

Under current Medicaid regulations, Federal matching funds (FFP) are not available in expenditures for Medicaid services provided to an individual who is an inmate of a public institution. In addition, FFP is not available in expenditures for a patient under age 65 in an institution for mental diseases or tuberculosis unless the individual is under age 22 and receiving inpatient psychiatric services. However, regulations provide an exception for noninstitutional services furnished during the month in which the individual becomes an inmate or patient. We are proposing to remove this exception and clarify that no Federal Medicaid funds are available for any services to those individuals from the date of admission to the date of discharge. The change would bring the regulations into conformance with the Medicaid statute.

Centers for Medicare and Medicaid Services, U.S.↗

Importance of National Institute of Infectious Diseases and Institutes of Public Health on control of infectious diseases in the new century.

As the incidence of infectious diseases has recently decreased, we are faced with new problems, such as emerging and re-emerging infectious diseases, food poisoning, zoonosis, and bio-terrorism. In light of these new conditions, the National Institute of Infectious Diseases, the Local Institutes of Public Health, public health offices, and other medical organization must maintain close relationship in order to protect the health and safety of the citizens.

Communicable Disease Control↗

[On the problems of getting an opinion, finding a decision when working in psychiatrie institutions. - Experiences with counselling a psychiatrie institution (author's transl)].

Exemplifying an occurrence within an every day's situation of a clinic makes obvious, how conflicts between claims of treatment and therapeutic reality can be present and painfully discussed. This can appear within that space of tension which is immanent to a institution of that kind. Emphasis is laid on the importance of institutional Counseling for the solving of these problems.

Counseling↗

Asthma in pregnancy. National Asthma Education Program Working Group on Asthma and Pregnancy. National Institutes of Health, National Heart, Lung and Blood Institute.

This manuscript is a summary of a comprehensive report dealing with asthma and pregnancy issued by the working group on Asthma and Pregnancy, National Institutes of Health (NIH), National Heart, Lung, and Blood Institute. The report was developed by a panel of obstetricians, pharmacologists, internists, allergists, and pulmonologists, who met over an 18-month period under the auspices of the NIH. Undertreatment of pregnant asthmatics, partially because of unfounded fears of adverse pharmacologic effects on the developing fetus, remains the major problem in the management of asthma during pregnancy in the United States. The four key components of asthma management during pregnancy are: 1) objective assessment of maternal lung function and fetal well-being, 2) avoidance or control of environmental precipitating factors, 3) pharmacologic therapy, and 4) patient education.

Asthma↗

Consensus recommendations for the postmortem diagnosis of Alzheimer's disease. The National Institute on Aging, and Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer's Disease.

This report summarizes the consensus recommendations of a panel of neuropathologists from the United States and Europe to improve the postmortem diagnostic criteria for Alzheimer's disease. The recommendations followed from a two-day workshop sponsored by the National Institute on Aging (NIA) and the Ronald and Nancy Reagan Institute of the Alzheimer's Association to reassess the original NIA criteria for the postmortem diagnosis of Alzheimer's disease published in 1985. The consensus recommendations for improving the neuropathological criteria for the postmortem diagnosis of Alzheimer's disease are reported here, and the "position papers" by members of the Working Group that accompany this report elaborate on the research findings and concepts upon which these recommendations were based. Further, commentaries by other experts in the field also are included here to provide additional perspectives on these recommendations. Finally, it is anticipated that future meetings of the Working Group will reassess these recommendations and the implementation of postmortem diagnostic criteria for Alzheimer's disease.

Adult↗

Comparison of long-term care in an acute care institution and in a long-term care institution.

BACKGROUND: Acute care hospitals in Quebec are required to reserve 10% of their beds for patients receiving long-term care while awaiting transfer to a long-term care facility. It is widely believed that this is inefficient because it is more costly to provide long-term care in an acute care hospital than in one dedicated to long-term care. The purpose of this study was to compare the quality and cost of long-term care in an acute care hospital and in a long-term care facility. METHODS: A concurrent cross-sectional study was conducted of 101 patients at the acute care hospital and 102 patients at the long-term care hospital. The 2 groups were closely matched in terms of age, sex, nursing care requirements and major diagnoses. Several indicators were used to assess the quality of care: the number of medical specialist consultations, drugs, biochemical tests and radiographic examinations; the number of adverse events (reportable incidents, nosocomial infections and pressure ulcers); and anthropometric and biochemical indicators of nutritional status. Costs were determined for nursing personnel, drugs and biochemical tests. A longitudinal study was conducted of 45 patients who had been receiving long-term care at the acute care hospital for at least 5 months and were then transferred to the long-term care facility where they remained for at least 6 months. For each patient, the number of adverse events, the number of medical specialist consultations and the changes in activities of daily living status were assessed at the 2 institutions. RESULTS: In the concurrent study, no differences in the number of adverse events were observed; however, patients at the acute care hospital received more drugs (5.9 v. 4.7 for each patient, p < 0.01) and underwent more tests (299 v. 79 laboratory units/year for each patient, p < 0.001) and radiographic examinations (64 v. 46 per 1000 patient-weeks, p < 0.05). At both institutions, 36% of the patients showed anthropometric and biochemical evidence of protein-calorie undernutrition; 28% at the acute care hospital and 27% at the long-term care hospital had low serum iron and low transferrin saturation, compatible with iron deficiency. The longitudinal study showed that there were more consultations (61 v. 37 per 1000 patient-weeks, p < 0.02) and fewer pressure ulcers (18 v. 34 per 1000 patient-weeks, p < 0.05) at the acute care hospital than at the long-term care facility; other measures did not differ. The cost per patient-year was $7580 higher at the acute care hospital, attributable to the higher cost of drugs ($42), the greater use of laboratory tests ($189) and, primarily, the higher cost of nursing ($7349). For patients requiring 3.00 nursing hours/day, the acute care hospital provided more hours than the long-term care facility (3.59 v. 3.03 hours), with a higher percentage of hours from professional nurses rather than auxiliary nurses or nursing aides (62% v. 28%). The nurse staffing pattern at the acute care hospital was characteristic of university-affiliated acute care hospitals. INTERPRETATION: The long-term care provided in the acute care hospital involved a more interventionist medical approach and greater use of professional nurses (at a significantly higher cost) but without any overall difference in the quality of care.

Aged↗

Neuropathological research at the "Deutsche Forschungsanstalt fuer Psychiatrie" (German Institute for Psychiatric Research) in Munich (Kaiser-Wilhelm-Institute). Scientific utilization of children's organs from the "Kinderfachabteilungen" (Children's Special Departments) at Bavarian State Hospitals.

During National Socialism, the politically motivated interest in psychiatric genetic research lead to the founding of research departments specialized in pathological-anatomical brain research, the two Kaiser Wilhelm-Institutes (KWI) in Berlin and Munich. The latter was indirectly provided with brain material by Bavarian State Hospitals, to three of which "Kinderfachabteilungen" (Special Pediatric Units) were affiliated. As children became victims of the systematically conducted child "euthanasia" in these Special Pediatric Units, this paper will address the question whether and to which extent the organs from victims of child "euthanasia" were used for (neuro-) pathological research at the KWI in Munich. By means of case studies and medical histories (with focus on the situation in Kaufbeuren-Irsee), I will argue that pediatric departments on a regular base delivered slide preparations, that the child "euthanasia" conduced in these departments systematically contributed to neuropathological research and that slide preparations from victims of child "euthanasia" were used in scientific publications after 1945.

Academies and Institutes↗

NICE and LICE: lessons from a health district. National Institute for Clinical Excellence. Local institutes of clinical excellence.

This paper describes experiences of implementing guidance from the National Institute for Clinical Excellence (NICE) in the East Riding and Hull Health Authority area. Attempts have been made to integrate NICE guidance with the decision-making, service planning and monitoring processes but overall progress has been limited. Contributory reasons are explored, along with suggestions on how to ensure that NICE can help ensure effective and equitable services.

Academies and Institutes↗

Standards for plasma and serum proteomics in early cancer detection: a needs assessment report from the national institute of standards and technology--National Cancer Institute Standards, Methods, Assays, Reagents and Technologies Workshop, August 18-19, 2005.

NIST and the National Cancer Institute cosponsored a workshop on August 18-19, 2005, to examine needs for reference materials for early cancer detection. This meeting focused on standards, methods, assays, reagents, and technologies. Needs for plasma and serum proteomics, DNA methylation, and specimen reference collections were discussed, and recommendations from participants were solicited. This report summarizes the discussion and recommendations for proteomics reference materials.

Biomarkers, Tumor↗

["A research institute for psychiatry...". The development of the German Research Institution for Psychiatry in Munich between 1917 and 1945].

The "Deutsche Forschungsanstalt für Psychiatrie" (DFA) in Munich, one of the most important research institutes in the field of theoretical and clinical psychiatry was founded in 1917 by Emil Kraepelin. Its financial existence between the World Wars was guaranteed by enormous donations from the jewish American James Loeb. The scientific work done by Walther Spielmeyer (neuropathology), Felix Plaut (serology), Kurt Schneider (clinical psychiatry) and Ernst Rüdin (psychiatric genetics) earned the DFA the reputation as an international center for psychiatry and neurology. During the "Third Reich", Ernst Rüdin cooperated with the national socialist health system. His genetic concepts supported eugenic laws such as compulsory sterilization of psychotic patients. These complex interrelations underscore the DFA's importance for the recent history of medical science in Germany.

Academies and Institutes↗

Health-related quality of life among the least dependent institutional elderly compared with the non-institutional elderly population.

The purpose of this study was to investigate health-related quality of life (HRQOL) and functional ability among the least dependent elderly in residential care, and to compare them with information on the general population. A stratified systematic sample (n = 1,587) was drawn from a one-day census of patients in all public residential homes in Finland on December 2, 1991. Sixty-nine per cent of residents in 1992 were able to participate (n = 1,097) and 86% of them returned the questionnaire (n = 948), of which n = 795 were acceptable, the response rate being 72%. A postal survey was used for data collection. The personnel of residential homes were allowed to help residents complete the questionnaire, and 90% of respondents received such help. HRQOL was measured by the Nottingham Health Profile (NHP) and functional ability by a 14-item questionnaire. Finnish studies among the general population were used for comparisons. According to the NHP, the HRQOL appeared lower in institutional care and this was associated with the dependency level. Similarly, for most ADL items the general population had less restrictions than the least dependent residential care patients. In general, women expressed more difficulties in physical mobility and lack of energy than men. The longest stay elderly expressed better HRQOL. In multivariate models adjusted for age and gender those with poor vision had worse HRQOL in almost every dimension of NHP. Difficulties in speech were connected with emotional reactions and social isolation. Chronic illness limiting normal daily life predicted more problems in energy, pain, physical mobility, and emotional reactions. The married or widowed experienced less social isolation than single elderly. Higher education was related to better HRQOL in all NHP dimensions. Poorer perceived health was associated with lack of energy, pain, and emotional reactions. We conclude from these results that there are only a few clients in residential care whose HRQOL or functional ability compare with the non-institutionalized population.

Activities of Daily Living↗

Pion treatment of prostate carcinoma at Paul Scherrer Institute (formerly Swiss Institute for Nuclear Research (SIN)) from 1983 to 1992.

BACKGROUND: - Between 1983 and 1992 a total of 55 patients suffering from prostate cancer were treated with pions (pi-mesons) at the Paul Scherrer Institute in Villigen, Switzerland. This form of therapy was used at only three centers world wide on 245 patients with this diagnosis. Since the last project in Vancouver, Canada, was closed in 1994, this form of therapy has been relegated to the realm of history. METHODS: - In a retrospective analysis, the data of 49 of the 55 patients, that was qualified for evaluation was brought up-to-date and evaluated. Median and mean age at the time of therapy was 65 years. Advanced stage tumors were overly represented, in respect to T-stages (35/49 stage T3 and T4) and differentiation (11/49 G1). The treatment volumes were between 67 and 1330 cm(3), and the mean delivered dose was 32.2 pion-Gray. Survival probability, the probability of metastases and the local control rate were calculated according to Kaplan-Meier. RESULTS: - Seven of the 49 patients had already been diagnosed with metastatic disease before treatment began, 16 developed metastases during the follow-up observation period. Local control after 2 years was 89%, and after 5 years 83%. The survival rate after 2 years was 87%, and 66% after 5 years, excluding non-tumor related deaths. The rate of late toxicity was acceptable. CONCLUSIONS: - Seen in retrospect, pion treatment of prostate carcinoma proved to be an effective form of therapy with a low rate of late toxicity. But, in comparison to the possibilities offered by modern conventional radiation therapy, this method would certainly not be today's first choice.

Aged↗

From the National Institute of Allergy and Infectious Diseases. Summary of the National Institutes of Health workshop on group B streptococcal infection.

Group B streptococci remain a serious cause of morbidity and mortality in neonates. GBS vaccine or immunoglobulin administered iv may enhance neonatal GBS immunity. Likewise, intrapartum antibiotic therapy of colonized mothers appears to reduce vertical transmission of group B streptococci and to prevent both maternal and neonatal GBS disease. However, the safety and effectiveness of routine penicillin prophylaxis less than or equal to 1 hr after birth remain in question. For example, penicillin prophylaxis appears to be of little value in infants with low birth weights (less than 2,000 g) who become symptomatic shortly after birth; however, it may reduce the incidence of disease in larger, full-term infants who acquire the group B streptococci at delivery or in the few hours immediately thereafter. The potential harm of administering penicillin to all neonates must also be considered, since routine antibiotic therapy may alter the incidence of both neonatal infections due to penicillin-resistant pathogens and possible later penicillin allergy. Theoretically, a single injection of penicillin at birth may suppress GBS disease in some neonates but not effectively treat it, allowing the disease to progress prior to diagnosis and therapy. The decision to use penicillin routinely in neonates to prevent GBS disease must therefore be made with caution. Presently, this decision must be made on a situational basis, with institutions having a high incidence of early-onset GBS disease electing to use penicillin only if the potential benefits outweigh the risks.

Anti-Bacterial Agents↗

Medicaid program; federal financial participation for inmates in public institutions and individuals in an institution for mental diseases; correction--HCFA.

This document corrects errors in a final rule published in the Federal Register on April 3, 1985 (50 FR 13196) on Federal financial participation for services furnished to certain institutionalized individuals. That final rule contained obsolete references to institutions for tuberculosis and an incorrect cross reference.

Centers for Medicare and Medicaid Services, U.S.↗