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Executive dyscontrol: an important factor affecting the level of care received by older retirees.

OBJECTIVES: To examine the relative contributions of Executive Control Function (ECF), general cognition, mood, problem behavior, physical disability, demographic variables, and the number of prescribed medications to the level of care received by older retirees. DESIGN: Multivariate regression and discriminant modeling. SETTING: A single Continuing Care Retirement Community (CCRC) in San Antonio, Texas. PARTICIPANTS: A total of 107 older retirees (mean age = 83.7+/-7.2 years), including 17 community-dwelling, well, older controls and 90 CCRC residents. CCRC subjects represented a convenience sample of consecutive referrals for geropsychiatric assessment. Sixty-one subjects resided at a noninstitutionalized level of care, and 46 were institutionalized. MEASUREMENTS: Tests of ECF (the Executive Interview (EXIT25)), general cognition (the Mini-Mental State Examination (MMSE)), mood (the Geriatric Depression Scale short-form (sGDS)), problem behavior (the Nursing Home Behavior Problem Scale (NHBPS)), physical disability (the Cumulative Illness Rating Scale (CIRS)), age, gender, years of education, and the number of prescribed medications were studied. RESULTS: All variables except gender and education varied significantly across level of care. Four variables made significant independent contributions; EXIT25 score (r2 = .48, P< .001), medication usage (partial r2 = .11, P<.001), sGDS score (partial r2 = .06, P = .001), and problem behavior (partial NHBPS r2 = .04, P<.04). These variables accounted for 69% of the total variance in level of care (R2 = .69; F (df 7,99) = 32.1, P<.001). A discriminant model based on the number of prescribed medications, EXIT25, sGDS, and NHBPS scores classified 83.2% of cases correctly (Wilke's lambda = .50, F(5,101) = 20.1; P<.001). The MMSE enters but fails to contribute significantly, independent of the other variables. Age and CIRS scores fail to enter. CONCLUSIONS: Cognitive (particularly ECF) impairment contributes most to the observed variance in level of care received by older retirees in this CCRC. In contrast, markers of general cognition, depression, and physical illness contributed relatively little additional variance. ECF is not detected well by traditional cognitive measures and must be sought by specific tests. Further study is needed to replicate these findings in other populations.

Activities of Daily Living↗

Home-based behavioral treatment of young children with autism.

This study evaluated the impact of intensive behavioral treatment on the development of young autistic children. The treatment reported in this study was home based and was implemented by parents of autistic children with the assistance of community-based clinicians. Although treatment was unable to be observed directly, parents reported that therapy was based on methods developed by Lovaas et al. (1981). Treatment differed from that described in previous reports of intensive behavior therapy for this population in that it was implemented outside an academic setting and for a shorter period. In addition, children received fewer hours per week of therapy than in previous reports. Children in the experimental treatment group were pairwise matched to children in a control group (who received conventional school-based and brief one-on-one interventions) on the basis of pretreatment chronological and mental age, diagnosis (autism vs. PDD), and length of treatment. The groups did not differ on pretreatment IQ. Children receiving the experimental treatment had significantly higher posttreatment IQ scores. Smaller, but still statistically significant effects on symptom severity were also found, though experimental subjects still met diagnostic criteria for autism or PDD.

Autistic Disorder↗

Hazards of imidacloprid seed coating to Bombus terrestris (Hymenoptera: Apidae) when applied to sunflower.

Seed coating treatments of sunflower by the systemic insecticide imidacloprid was suspected of affecting honey bees and bumblebees. The hypothesis raised was whether imidacloprid could migrate into nectar and pollen, then modify flower attractiveness, homing behavior, and colony development. Our greenhouse and field experiments with Bombus terrestris L. were aimed at the following: the behavior of workers foraging on treated and control plants blooming in a greenhouse, the homing rate of colonies placed for 9 d in a treated field compared with colonies in a control field, and the development of these 20 colonies under laboratory conditions when removed from the fields. In the greenhouse, workers visited blooming heads of treated and control plants at the same rate and the mean duration of their visits was similar. In field colonies, analysis of pollen in hairs and pellets of workers showed that in both fields 98% of nectar foragers visited exclusively sunflowers, whereas only 25% of pollen gatherers collected sunflower pollen. After 9 d, in the control and treated field, 23 and 33% of the marked foragers, respectively, did not return to hives. In both fields, workers significantly drifted from the center to the sides of colony rows. During the 26-d period under field and laboratory conditions, the population increase rate of the 20 colonies was 3.3 and 3.0 workers/d in hives of the control and treated field, respectively. This difference was not significant. New queens were produced in eight colonies in either field. The mean number of new queens per hive was 17 and 24 in the control and treated field, respectively. Their mating rate was the same. It was concluded that applying imidacloprid at the registered dose, as a seed coating of sunflowers cultivated in greenhouse or in field, did not significantly affect the foraging and homing behavior of B. terestris and its colony development.

Animals↗

Home-based behavioral health intervention: Use of a telehealth model to address poor adherence to type-1 diabetes medical regimens.

Youth with insulin-dependent diabetes mellitus face complex treatment regimens and often have difficulty adhering to treatment requirements. Many behavioral-health intervention strategies, such as psychoeducational groups, diabetes summer camps, individual therapy, and residential treatment have been utilized to address this issue. While some have been effective, many barriers exist that limit the number of youth who are able to utilize these treatments. Additionally, the effectiveness of these treatments does not typically generalize to the home environment. Telephone-based, intensive, behavioral-health interventions may address barriers to treatment access by providing lower cost treatment that is easier to access for youth who do not live near a knowledgeable behavioral-health specialist. Additionally, delivery via telephone enables the interventions to take place in the home. This, in combination with parental involvement in the treatment, may increase generalization of the positive treatment outcomes to the home environment. The purpose of this paper is to describe a controlled trial of a telehealth intervention for youth whose diabetes is poorly managed. Preliminary outcome data for the trial are promising. Representative cases from the trial are presented in case-study format.

Adolescent↗

Situational variation in problem behavior at home and school in attention deficit disorder with hyperactivity: a factor analytic study.

The present investigation assesses situational variation in problem behaviors of children with Attention Deficit Disorder with Hyperactivity. Principal-component factors (VARIMAX rotation) were computed for the Home/School Situations Questionnaires (HSQ/SSQ). For the HSQ, four factors emerged, accounting for 61% of variance. For the SSQ, three factors emerged, accounting for 68% of variance. Factors were similar to those previously derived with non-referred children. To assess discriminative power, factors were compared (t-tests) to previous data. All factors significantly discriminated ADD/H from non-referred children. These data suggest the factors add to the utility of the HSQ/SSQ in assessing ADD/H.

Attention Deficit Disorder with Hyperactivity↗

Home-orienting behavior in rat pups: the effect of 2 and 3 generations of rehabilitation following intergenerational malnutrition.

In an earlier study in this laboratory, we examined home-orienting ability in rats with histories of intergenerational malnutrition that were rehabilitated postnatally with an adequate protein diet (Galler, 1979). Despite increased size and activity, 1st-generation rehabilitated pups showed no improvement in homing ability when compared to malnourished pups. In the current study, offspring of rats with intergenerational malnutrition were rehabilitated for 2 additional generations and tested for homing ability from postnatal Day 4 through Day 12. The pups rehabilitated for 2 and 3 generations did not perform as well as control pups, even though growth and activity returned to normal levels. Furthermore, the rehabilitated pups failed to demonstrate any preference for the nest on all days of testing; in contrast, control pups favored the nest quadrant by Day 8 of life. No significant improvement was evident on any measure from the 2nd to the 3rd generation of rehabilitation.

Animals↗

Mucosa-associated (beta 7-integrinhigh) lymphocytes accumulate early in the pancreas of NOD mice and show aberrant recirculation behavior.

The mucosal addressin cell adhesion molecule-1 (MAdCAM-1) becomes expressed on islet vessels of NOD mice early during lymphocyte accumulation in islets. Because MAdCAM-1 preferentially mediates the homing of mucosal lymphocytes, islet-associated MAdCAM-1 could favor the accumulation of mucosal lymphocytes in pancreatic islets. Therefore, we investigated the relative frequency of islet-infiltrating lymphocytes with a mucosal phenotype (alpha 4/beta 7-integrinhigh and L-selectinlow) at early and advanced stages of insulitis. We found that until the age of 12 weeks, lymphocytes with a mucosal phenotype were particularly frequent in the pancreas (percentage of beta 7-integrinhigh-lymphocytes was 48% at 8 weeks and 73% at 12 weeks), whereas in diabetic mice older than 16 weeks, their relative number was smaller (26% of pancreas-infiltrating lymphocytes). To define the origin and homing behavior of beta 7-integrinhigh-lymphocytes before their accumulation in pancreatic islets in NOD mice, we sought for such lymphocytes in different lymphoid organs and studied their recirculation. We found that compared with lymphocytes in several other strains, in NOD mice such lymphocytes were most frequent in nonmucosal lymphoid tissues (peripheral and pancreatic lymph nodes, spleen) from an early age. When injected to blood circulation, mucosal beta 7high-lymphocytes failed to home efficiently back to mucosal lymphoid tissue in NOD mice but homed aberrantly to nonmucosal lymphoid tissues. After adoptive transfer of diabetogenic splenocytes, the first lymphocytes accumulating in the pancreas were predominantly beta 7-integrinhigh. We conclude that mucosa-associated lymphocytes are involved in the early phases of islet-inflammation in NOD mice and that the aberrant homing behavior of lymphocytes expressing high levels of beta 7-integrin may associate with their accumulation in pancreatic islets early during insulitis.

Aging↗

[Facilities for the aged from an environment psychology viewpoint. An analysis of relationship between ratings of social climate and behavior of home residents].

We present a concept for the quantification of "social climate" in institutions for the aged. To receive such evaluations from the aged, according to our experience, it is necessary to apply special techniques of exploration to reduce response sets of defense and facade. Comparing different institutions and analysing the correlations with behavioral data we can demonstrate the usefulness of these environmental variables. Differential results point to the fact that some characteristics of the aged have to be considered to interpret these variable of "social climate".

Aged↗

Home-based behavioral treatments for chronic benign headache: a meta-analysis of controlled trials.

Controlled clinical trials have consistently demonstrated that behavioral treatments for chronic benign headache produce clinically beneficial outcomes both post-treatment and at follow-up. Given these results there is interest in cost-reduction and redesign of these treatments to improve their accessibility. One promising approach in this regard is home-based headache treatment. These treatments seek to provide the same amount of treatment as clinic-based treatments; however, some of the material typically presented to the patient by a clinician is presented through home-study materials (e.g., manuals, audiotapes). To date, the published literature contains 20 controlled clinical trials which have examined the outcomes produced by home-based treatments. This article presents the first comprehensive meta-analysis of these clinical outcome studies. Results of the quantitative analyses suggest that home-based treatments produce comparable, or with certain outcome measures, superior results to clinic-based treatments. Moreover, costeffectiveness scores of home-based treatments were found to be more than five times larger than those of clinic-based therapies. Methodological analyses are also presented along with suggestions for future research.

Adolescent↗

Comparison of child adaptation to epilepsy and asthma.

Self-concept, home behavior and school behavior of 128 children with epilepsy and 126 children with asthma were measured in order to compare and contrast differences in psychosocial adaptation. Results indicated that children with epilepsy were experiencing significantly poorer psychosocial adaptation (p less than .001) in all three areas. An exploration of gender differences across groups indicated that girls were more at risk for the home behavior problems of depression, somatic complaints, social withdrawal and hyperactivity than boys. Clinical implications for interventions with these two populations are discussed.

Adaptation, Psychological↗

[Nutritional balance of breakfast of children 7 to 11 years of age: comparison between school health education and eating behavior at home].

Following the favourable impact of a health education programme carried out in a school setting concerning "healthy eating at breakfast", the consumption of food at home for all meals, and separately at breakfast time was evaluated by using a "food-frequency" questionnaire. These results were then compared with the results of the school health education programme which focused primarily on breakfasts. The results of the survey, which included 80 children between 7 and 11 years old, show a great stability in the choice of foods, and during the action interesting variations concerning the respective proportions of nutriments according the recommended dietary allowances. We noticed an increase in the consumption of glucides, starch, vegetable proteins, and certain micronutriments. These changes are minor, but they may have a great importance if they spread to the whole nutrition. One can advise to generalise such school health education interventions.

Child↗