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Gauge freedom in orbital mechanics.

Both orbital and attitude dynamics employ the method of variation of parameters. In a non-perturbed setting, the coordinates (or the Euler angles) are expressed as functions of the time and six adjustable constants called elements. Under disturbance, each such expression becomes ansatz, the "constants" being endowed with time dependence. The perturbed velocity (linear or angular) consists of a partial time derivative and a convective term containing time derivatives of the "constants." It can be shown that this construction leaves one with a freedom to impose three arbitrary conditions on the "constants" and/or their derivatives. Out of convenience, the Lagrange constraint is often imposed. It nullifies the convective term and thereby guarantees that under perturbation the functional dependence of the velocity upon the time and "constants" stays the same as in the undisturbed case. "Constants" obeying this condition are called osculating elements. The "constants" chosen to be canonical, are called Delaunay elements, in the orbital case, or Andoyer elements, in the spin case. (Because some of the Andoyer elements are time dependent, even in the free-spin case, the role of "constants" is played by the initial values of these elements.) The Andoyer and Delaunay sets of elements share a feature not readily apparent: in certain cases the standard equations render these elements non-osculating. In orbital mechanics, elements calculated via the standard planetary equations turn out to be non-osculating when perturbations depend on velocities. To keep elements osculating under such perturbations, the equations must be amended with additional terms that are not parts of the disturbing function (Efroimsky and Goldreich 2003, 2004). For the Kepler elements, this merely complicates the equations. In the case of Delaunay parameterization, these extra terms not only complicate the equations, but also destroy their canonicity. So under velocity-dependent disturbances, osculation and canonicity are incompatible. Similarly, in spin dynamics the Andoyer elements turn out to be non-osculating under angular-velocity-dependent perturbation (a switch to a noninertial frame being one such case). Amendment of the dynamical equations only with extra terms in the Hamiltonian makes the equations render nonosculating Andoyer elements. To make them osculating, more terms must enter the equations (and the equations will no longer be canonical). It is often convenient to deliberately deviate from osculation by substituting the Lagrange constraint with an arbitrary condition that gives birth to a family of nonosculating elements. The freedom in choosing this condition is analogous to the gauge freedom. Calculations in nonosculating variables are mathematically valid and sometimes highly advantageous, but their physical interpretation is nontrivial. For example, nonosculating orbital elements parameterize instantaneous conics not tangent to the orbit, so the nonosculating inclination will be different from the real inclination of the physical orbit. We present examples of situations in which ignorance of the gauge freedom (and of the unwanted loss of osculation) leads to oversights.

Journal Article↗

Extended middle fossa approach: quantitative analysis of petroclival exposure and surgical freedom as a function of successive temporal bone removal by using frameless stereotaxy.

OBJECT: Conventional wisdom regarding skull base surgery says that more extensive bone removal equals greater exposure. Few researchers have quantitatively examined this assertion, however. In this study the authors used a frameless stereotactic system to measure quantitatively the area of petroclival exposure and surgical freedom for manipulation of instruments with successive steps of temporal bone removal. METHODS: With the aid of high-power magnification and a high-speed drill, 12 cadaveric specimens were dissected in four predetermined, successive bone removal steps: 1) removal of the Kawase triangle; 2) removal of the Glasscock triangle; 3) removal of the cochlea together with skeletonization of the anterior internal auditory canal; and 4) inferior displacement of the zygoma. Step 1 offered 62 +/- 43 mm2 of exposed petroclival area, with 84 +/- 69 mm2 of surgical freedom; Step 2, 61 +/- 22 and 76 +/- 58 mm2; Step 3, 128 +/- 47 and 109 +/- 87 mm2; and Step 4, 135 +/- 38 and 102 +/- 69 mm2, respectively. CONCLUSIONS: The middle fossa approach provided a means surgically to expose the petroclival area. When examined quantitatively by using a frameless stereotactic device, the authors determined that the removal of the cochlea and skeletonization of the anterior internal auditory canal (Step 3) provided the most significant increase in both exposure and surgical freedom. Removal of the zygoma improved neither exposure nor surgical freedom.

Cadaver↗

[The normative concept of guilt in criminal law between freedom of will and neurobiological determinism].

To make criminal conduct liable to punishment, criminal responsibility, defined as individual blameworthiness in terms of social ethics, is required as point of reference--both to create and limit the state's right to punish the offender. Neurobiological findings and more recent investigations in brain research have given rise to serious doubts regarding this "conditio sine qua non" of the state's power monopoly. As a result of preceding unconscious decisions, so the argument goes, Man is not free in his will, and the normative principle of culpability would need to be relinquished in favour of a "law of measures" detached from guilt. A detailed analysis of the underlying experimental setups, in particular the investigations by Benjamin Libet involving the measurement of the readiness potential, has shown, however, that the results of the test methods do not justify the demand for a profound change up to the point of a total revision of criminal law, and that they cannot invalidate the concept of freedom of will apostrophised on principle. The empirical data obtained fail to demonstrate if and why decisions of the will should not be free, the more so as the nomothetic method used ignores completely the idiographic understanding and interpretation of the always context-related and socio-structurally (pre)-moulded personality of the offender. Performed in a laboratory setting as individual actions with a comparatively simple structure and unrelated to a concrete situation, they can by no means be translated to the (more) complex situation under which an offence is committed including the decision-making processes determined by psychodynamic, motivational and intentional aspects as well as highly specific reciprocal interactions within the offender-victim constellation. Even if these experiments had shown the determined nature of human decisions, they would not necessarily have to bring about a conceptual change of paradigms of the normative concept of guilt, because as a result of self-attribution, the intra- and inter-subjective experience of the freedom of will renders the mere "illusion of freedom" sufficient to assign to an individual the appropriate sense of responsibility, which is also accepted by him. The alternative of a law of measures independent of guilt and culpability must be rejected because it is incapable of instituting sufficient protection, both in qualitative and quantitative terms, against prognostically diffuse and utilitarian hypertrophied prophylactic efforts on the part of the state up to the point of a revolutionised anthropological design, as shown quite clearly by the repressive and restrictive tendencies apparent in criminal policy since 11 September 2001. Consequently, the classic principle of guilt as one of the humanitarian foundations of punishment imposed by the state needs to be protected and upheld in the face of rash and inadequately considered law amendment endeavours. With its principles having slowly grown over the ages under democratic consent, criminal law is capable of immunising itself against uncritically generalised restructuring attempts based on inductive false conclusions and the confusion of coincidence, correlation and causality, let alone against the neurobiological "occupation tendencies" of normative premises. Regardless of their undeniable fascination, future brain research activities and the respective findings in the neurobiology of thinking, decision-making and acting as an indispensable empirical and epistemological starting point must always be reviewed in terms of their factual and normative implementation powers in favour of or against the human freedom of will.

Antisocial Personality Disorder↗

Freedom Set II--a Y-set CAPD system with a novel design.

The Freedom Set II is designed with a three-way valve to control the direction of dialysate flow thus simplifying the procedure and decreasing training time. Twenty-four patients from two centers were trained on the Freedom Set II and were observed for ninety patient months. Five patients who had been on other bagless systems expressed their preference for the Freedom Set II. The peritonitis rate for the observation period was one episode every 21 patient months. We conclude that the Freedom Set II provides safe, cost-effective dialysis and simplifies the CAPD procedure.

Consumer Behavior↗

[Practitioner's freedom to prescribe in relation to the requirements of the AMM, the medical references and the socioeconomic constraints].

The freedom of prescription is registered in texts which have a legislative value: le Health Code, the social security code, the medical deontology code. The control of prescription conditions for certain classes of medicines meets some economic and Health targets. The authorization to put products on the market concerns the medicines produced industrially. The instructions and opposing medical references are tools that could allow "the medicalized control of Health cost evolution" mandated by the National Convention which links the liberal doctors and the organisms of social protection. Their non-respect can involve sanctions for the doctors who have signed the convention but do not constitute at the very outset a fault in the words of civil liability. The freedom of prescription, information and consent of the patient are undissociable. In the name of freedom the responsibility of the practitioner is involved. The faults are classified in two categories: breach of medical humanism, breach of rules of medical art. The aim of the regulation consists in the optimum prescription. Freedom and regulation go together with professionalism and good citizenship.

Drug Prescriptions↗

Freedom, responsibility, and health.

Freedom and responsibility, how much of each and how they are balanced, have profound implications for our personal lives and for our work. The health of a population and its achievement in the workplace are enhanced when individuals have some freedom and some responsibility, but not too much of either, and when civil associations of individuals rather than individuals acting alone are the essential social units. The consistent association of social contacts with health and productivity provides strong support for the premise that intimate relationships are the focus around which people's lives revolve. Membership of a "social network" may be merely conforming to a reigning social norm, and this could mean having to pay an important price in the loss of creativity associated with individualism. But social conformity should not prevent individuals from going their own way, and it should be possible to combine the luxury of individuality with an active life in civic affairs. Less than complete freedom may fall short of existential utopia, but it may be best for our health and wellbeing.

Freedom↗

Gender differences in the effect of visual sexual stimulation on the perceived covariation between freedom and responsibility.

The authors replicated and extended a test of Epstein's cognitive-experiential self-theory (CEST; S. Epstein, 1973, 1980, 1985, 1994, 2003) regarding subjective estimates of the relationship between freedom and responsibility. CEST predicts that information in the form of sexually provocative images is likely to be processed by the experiential system. The authors' hypothesis was that such experiential processing would cause an increase in the likelihood of participants endorsing as true a statement that proposed a negative correlation between freedom and responsibility. University students (N = 97) in introductory psychology classes viewed 25 images of either men or women in provocative clothing, or a control consisting of academic journal covers, after which they responded to 24 statements proposing either a positive, negative, or noncontingent relationship between freedom and responsibility. Judgments were analyzed according to perceiver gender and target gender, as well as the framing of the proposition and its contingency category. The hypothesis was supported for the men and to a lesser extent for the women. Although priming the experiential system by exposing participants to sexually provocative images did not change endorsement rates of positive contingencies, it did lead to an increase in the likelihood of simultaneously endorsing negative contingencies.

Adult↗

[The interactive effect of initial position and threat to freedom on psychological reactance].

An experiment was conducted to examine which was crucial for the reactance effect on attitude change: discrepancy, initial position or prerequisite conditions for reactance arousal. Initial receiver attitudes were one of the five levels: moderate or extreme agreement (the least discrepancy), slight agreement, neutral, slight disagreement, and moderate or extreme disagreement (the most discrepancy), and threat to attitudinal freedom was manipulated. Prerequisite conditions for reactance arousal were also measured. Threat manipulation significantly reduced opinion change only among receivers at neutral or moderate/extreme disagreement position. In addition, examination of prerequisites showed that compliance in high threat condition was significantly less for receivers who had been uncertain about their own initial position and had perceived the issue important (freedom-of-choice group) and those who had perceived the attacked position as both possible and important (freedom-of-position group). Theoretical and practical significance of prerequisites for reactance arousal is discussed.

Adult↗

[Freedom in a little box].

What are the implications for health of freedom as a community value? This article focuses on the fact that both health and freedom are complex concepts that elude a concise definition. Depending on how you define them, the answer to the question above will vary. Different conceptions of health and freedom are described initially, and then their interdependence is illustrated by means of examples. One issue examined is how the breakdown of the communist regime in the former Soviet Union influenced life expectancy, another the positive and negative aspects of the Cuban health system. Finally, the importance of a questioning attitude to the two concepts is underlined.

Attitude to Health↗

[Freedom in disorders of the mind and spirit].

The much used and popular word "freedom" is being examined as to its significance and in that context the peculiar expression "freedom of will" is also brought into the discussion. In the course of this clarification, philosophy, jurisprudence, poetic-literary and our everyday language all had to lend a hand. In its application to psychic abnormal and sick persons one finds that in the endogenous psychoses, because of the profound change of existence, some patients experience the freedom of being for the very first time; this, however, can in the course of the illness turn into its opposite.

Bipolar Disorder↗

Initial experience of US Marine Corps forward resuscitative surgical system during Operation Iraqi Freedom.

HYPOTHESIS: Modern US Marine Corps (USMC) combat tactics are dynamic and nonlinear. While effective strategically, this can prolong the time it takes to transport the wounded to surgical capability, potentially worsening outcomes. To offset this, the USMC developed the Forward Resuscitative Surgical System (FRSS). By operating in close proximity to active combat units, these small, rapidly mobile trauma surgical teams can decrease the interval between wounding and arrival at surgical intervention with resultant improvement in outcomes. DESIGN: Case series. SETTING: Echelon 2 surgical units during the invasion phase of Operation Iraqi Freedom. PATIENTS: Ninety combat casualties, consisting of 30 USMC and 60 Iraqi patients, were treated in the FRSS between March 21 and April 22, 2003. INTERVENTIONS: Tactical surgical intervention consisting of selectively applied damage control or definitive trauma surgical procedures. MAIN OUTCOME MEASURES: Time to surgical intervention and outcome following treatment in the FRSS. RESULTS: Ninety combat casualties with 170 injuries required 149 procedures by 6 FRSS teams. The USMC patients were received within a median of 1 hour of wounding with the critically injured being received within a median of 30 minutes. Fifty-three USMC personnel were killed in action and 3 died of wounds for a killed in action rate of 13.5% and a died of wounds rate of 0.8% during the invasion phase of Operation Iraqi Freedom. All Marines treated in the FRSS survived. CONCLUSION: The use of the FRSS in close proximity to the point of engagement during the initial, dynamic combat phase of Operation Iraqi Freedom prevented delays in surgical intervention of USMC combat casualties with resultant beneficial effects on patient outcomes.

Blast Injuries↗

Degrees of freedom in interspecific allometry: an adjustment for the effects of phylogenetic constraint.

The data used in studies of bivariate interspecific allometry usually violate the assumption of statistical independence. Although the traits of each species are commonly treated as independent, the expression of a trait among species within a genus may covary because of shared common ancestry. The same effect exists for genera within a family and so on up the phylogenetic hierarchy. Determining sample size by counting data points overestimates the effective sample size, which then leads to overestimating the degrees of freedom that should be used in calculating probabilities and confidence intervals. This results in an inflated Type 1 error rate. Although some workers (e.g., Felsenstein [1985] Am. Nat. 125:1-15) have suggested that this issue may invalidate interspecific allometry as a comparative method, a correction for the problem can be approximated with variance components from a nested analysis of variance. Variance components partition the total variation in the data set among the levels of the nested hierarchy. If the variance component for each nested level is weighted by the number of groups at that level, the sum of these values is an estimate of an effective sample size for the data set which reflects the effects of phylogenetic constraint. Analysis of two data sets, using taxonomy to define levels of the nested hierarchy, suggests that it has been common for published studies of interspecific allometry to severely overestimate the number of degrees of freedom. Interspecific allometry remains an important comparative method for evaluating questions concerning individual species that are not similarly addressed by the format of most of the newer comparative methods. With the correction proposed here for estimating degrees of freedom, the major statistical weakness of the procedure is substantially reduced.

Analysis of Variance↗

Lagrangian molecular dynamics using selected conformational degrees of freedom, with application to the pseudorotation dynamics of furanose rings.

Using internal conformational degrees of freedom for biopolymers as natural variables, and introducing a Lagrangian dynamics approach, one can simulate time-dependent processes over a much longer time scale than in classical Newtonian molecular dynamics (MD) techniques. Two factors contribute to this: a substantial reduction in the number of degrees of freedom and a very large increase in the size of the time step. We present the Lagrangian equations of motion for repuckering transitions in model furanose (F), ribose (R), and 2'-deoxyribose (dR) ring systems using the pseudorotation phase angle as the single dynamic variable. As in most Lagrangian analyses, the effective masses for the R and dR models are dependent on conformation, and we test the behavior of this variable mass (VM) model. Since the variation in effective mass is small, the VM model is compared with a simplified constant mass (CM) model, which is shown to be an excellent approximation. The equations of motion for the CM and VM models are integrated with the leapfrog and the iterative leapfrog algorithms, respectively. The Lagrangian dynamics approach reduces the number of degrees of freedom from about 40 to 1, and allows the use of time steps on the order of 20 fs, about an order of magnitude greater than is used in conventional MD simulations.

Biopolymers↗

Sample size calculations for disease freedom and prevalence estimation surveys.

We developed a Bayesian approach to sample size calculations for studies designed to estimate disease prevalence that uses a hierarchical model for estimating the proportion of infected clusters (cluster-level prevalence) within a country or region. The clusters may, for instance, be villages within a region, cities within a state, or herds within a country. Our model allows for clusters with zero prevalence and for variability in prevalences among infected clusters. Moreover, uncertainty about diagnostic test accuracy and within-cluster prevalences is accounted for in the model. A predictive approach is used to address the issue of sample size selection in human and animal health surveys. We present sample size calculations for surveys designed to substantiate freedom of a region from an infectious agent (disease freedom surveys) and for surveys designed to estimate cluster-level prevalence of an endemic disease (prevalence estimation surveys). In disease freedom surveys, for instance, assuming the cluster-level prevalence for a particular infectious agent in the region is greater than a maximum acceptable threshold, a sample size combination consisting of the number of clusters sampled and number of subjects sampled per cluster can be determined for which authorities conducting the survey detect this excessive cluster-level prevalence with high predictive probability. The method is straightforward to implement using the Splus/R library emBedBUGS together with WinBUGS.

Animals↗

Transitions in a postural task: do the recruitment and suppression of degrees of freedom stabilize posture?

In this study, we examined flexibility in postural coordination by inducing transitions between postural patterns. Previous work demonstrated that the postural control system produces two task-specific postural patterns as a function of the frequency of support surface translation. For slow translation frequencies (<0.5 Hz), subjects ride on the platform reminiscent of upright stance (ride pattern), and for fast frequencies (> or =0.75 Hz) subjects actively fixed the head and trunk in space (head fixed pattern) during anterior-posterior platform motion. To study the adaptation of the postural control system, we had subjects stand on a support surface undergoing increases (from 0.2 to 1.0 Hz in 0.1-Hz steps) and decreases (from 1.0 to 0.2 Hz in 0.1-Hz steps) in translation frequency with the eyes open and closed. Kinematic measures of sagittal plane body motion revealed a gradual transition between these two postural patterns as a function of frequency scaling. In both the increasing and decreasing frequency conditions with visual input, center of mass displacements gradually decreased and increased, respectively, whereas upper-trunk (and head) displacement decreased gradually within the ride pattern until a head fixed pattern was observed without any significant changes in displacement for translation frequencies at and above 0.6 Hz. Without visual input, the scaling of the ride pattern was similar except the transition to the head fixed pattern never emerged with increasing frequency; instead, a less stable pattern exhibiting slow drift in head-trunk anterior-posterior motion (drift pattern) was observed at and above 0.5 Hz oscillations. The stability of the head fixed pattern at fast frequencies was clearly dependent on visual input suggesting that vision was more critical for trunk and head control in space at high than low translation frequencies. Head velocity was kept constant, and lower with vision, as translation frequency (and velocity) changed suggesting a head velocity threshold constraint across postural patterns. The gradual transition from the ride to the head fixed pattern was made possible by the recruitment of available degrees of freedom in the form of ankle, then knee, and then hip joint motion. In turn, the transition from the head fixed or drift pattern was made possible by the gradual suppression of available degrees of freedom in the form of reducing hip, then knee, and then ankle motion. The gradual change in postural kinematics without instabilities and hysteresis suggests that the ability to recruit and suppress biomechanical degrees of freedom allows the postural control system to gradually change postural strategies without suffering a loss of stability. The results are discussed in light of possible self-organizing mechanisms in the multisensory control of posture.

Adult↗

Dynamic complexity of visuo-motor coordination: an extension of Bernstein's conception of the degrees-of-freedom problem.

Extending Bernstein's spatial conception of the degrees-of-freedom problem in the human motor system, we introduce a method developed from the theory of non-linear dynamics that allows one to quantify the spatio-temporal, i.e. dynamic, complexity of visuo-motor coordination. The correlation dimension D is used to measure the effective number of dynamic degrees of freedom in the coordination that a subject uses when performing a visuo-motor tracking task. The validity of the estimator employed is demonstrated. Visuo-motor coordination had a low-dimensional (mean D-SD=6.07 -0.82) dynamic structure, which was consistent with deterministic chaos rather than with pure stochastic noise. D correlated with tracking performance, P. Both D and P were closely related to the degree of visuo-motor compatibility that the task presented to the subject. However, for short periods of training P increased, but D did not. As these seemingly contradictory results suggest, our dynamic conception of the degrees-of-freedom problem may reveal far more intricate visuo-motor interactions than Bernstein could identify on the basis of his spatial analyses of bodily movement patterns and by the methods of evaluation that were available to him at the time.

Adult↗

Thermal freedom of Graomys griseoflavus in a seasonal environment.

1. Thermal freedom, defined as the physiological potential to make full spatiotemporal use of the seasonal thermal macroclimate, was assessed in Graomys griseoflavus, a cricetid rodent inhabiting the Chaco Province in Argentina. 2. The extent of the physiological thermal range (58 degrees C) was larger than the seasonal thermal range (30-50 degrees C), favoring Graomys resistance to low winter temperatures. The upper physiological thermal limit was almost coincident with the highest extreme of summer temperatures. 3. Graomys thermal freedom is facilitated by a high evaporative water loss, high metabolic capability, wide thermal neutral zone and a 4 degrees C lability of body temperature. 4. Behavioral responses (thermal avoidance) are utilized by this species, but with no apparent loss in thermal freedom.

Acclimatization↗

Degrees of freedom and motor planning in purposive movement.

This paper presents empirical evidence suggesting that healthy humans can perform a two degree of freedom visuo-motor pursuit tracking task with the same response time delay as a one degree of freedom task. In contrast, the time delay of the response is influenced markedly by the nature of the motor synergy required to produce it. We suggest a conceptual account of this evidence based on adaptive model theory, which combines theories of intermittency from psychology and adaptive optimal control from engineering. The intermittent response planning stage has a fixed period. It possesses multiple optimal trajectory generators such that multiple degrees of freedom can be planned concurrently, without requiring an increase in the planning period. In tasks which require unfamiliar motor synergies, or are deemed to be incompatible, internal adaptive models representing movement dynamics are inaccurate. This means that the actual response which is produced will deviate from the one which is planned. For a given target-response discrepancy, corrective response trajectories of longer duration are planned, consistent with the principle of speed-accuracy trade-off. Compared to familiar or compatible tasks, this results in a longer response time delay and reduced accuracy. From the standpoint of the intermittency approach, the findings of this study help make possible a more integral and predictive account of purposive action.

Adult↗