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At least 91 records · Page 5Linked to original sources
PubMed1999

Ferula asa-foetida and Curcuma longa in traditional medical treatment and diet in Nepal.

Food and eating have powerful symbolic value among the hinduistically-influenced ethnic groups of Nepal. In addition, food plays a major role in the concepts of illness and curing and constitute an integral part of traditional medical prescriptions. Materials that are consumed in 0.5-1.5 g amounts in the daily diet (e.g. the spices turmeric and asafoetida) are used in minute amounts for medical purposes. Why? Three hypotheses are offered here to discuss this issue.

Animals↗
PubMed2001

Acute and chronic toxicity of fessoukh, the resinous gum of Ferula communis L, compared to warfarin.

The acute toxicity of the fessoukh extract (FE) was studied in rats and mice. In single oral dose administration mode, FE has moderate toxicity; the LD50s were 1650 mg/kg bw in rats and 2000 mg/kg bw in mice. In albino rats, with baits containing 0.01 to 10% FE, 0.01% produced 100% mortality in 15 d; with 0.1%, all rats died in 9 d. Baits containing 0.1% were toxic, more consumed, required less product and did not cause apprehension in the rats. A trial conducted with wild rats (Rattus norvegicus) using 0.1% FE baits demonstrated fessoukh's rodenticide effects.

Administration, Oral↗