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Minimally invasive exploration of the female reproductive tract in infertility.

Classically, invasive and non-invasive tests are performed to evaluate the causes of infertility. Transvaginal hydrolaparoscopy (THL) allows the exploration of the pelvic structures with a mini-endoscope, using a vaginal needle-guided trocar introduction technique and saline as a distension medium. A first study on 349 patients demonstrated the feasibility of the procedure and gave a high patient satisfaction. Access to the pouch of Douglas was achieved in 330 patients (94.5%) under local anaesthesia and in an ambulatory environment. The mean pain score measured on a visual analogue scale of 10 was 2.7, comparable to the score of mini-hysteroscopy only and significantly lower than the scores of hysterosalpingography with either metal cannula or balloon catheter. A total of 96% of the patients agreed to repeat the procedure under the same circumstances if required. The diagnostic accuracy of the technique was demonstrated in a prospective study, in which two independent endoscopists explored 10 patients with both THL and standard laparoscopy. The inter-observer agreement for ovarian adhesions was 75% for standard laparoscopy and 90% for THL. In addition, in patients with mild endometriosis, more peri-ovarian adhesions were detected with THL than with standard laparoscopy. A multinational survey to evaluate the risk and outcome of bowel injury during THL registered 24 (0.65%) cases in 3667 procedures. In all cases, the diagnosis was made immediately and the treatment was conservative without complications.

Endometriosis↗

Advances in the assessment of the uterus and fallopian tube function.

Hysterosalpingo-contrast-sonography (HyCoSy) using saline and Echovist is a well tolerated outpatient technique that provides a significant amount of information of relevance to the infertile woman that is not obtainable at hysterosalpingogram (HSG) whilst avoiding exposure to X-ray irradiation. When performed by experienced operators, it serves as a valuable, first-line screening test for the more invasive procedures of laparoscopy and dye chromopertubation and hysteroscopy. If detailed diagnostic information is required in women in whom there is no clinical or ultrasound evidence of pelvic pathology, the surgical technique of fertiloscopy can be considered to be appropriate. This technique permits confirmation that the ovum pick-up mechanism is normal, the tubes are patent and the uterine cavity is normal, while salpingoscopy and microsalpingoscopy permit the assessment of the tubal lumen.

Diagnostic Techniques, Obstetrical and Gynecologic↗

Incidental observations during routine laparoscopic sterilisation.

Chance observations made in 24 (0.91%) of the 2639 cases in whom tubal ligation was done by laparoscopic method in the department of obstetrics and gynaecology, Institute of Medical Sciences, Banaras Hindu University, Varanasi during the last 4 years are reported and analysed. Congenital anomalies of the reproductive tract (0.30%), pelvic adhesions with or without thickened tubes due to inflammatory causes (0.49%) and other abnormalities (0.11%) were visualised. It is concluded that surgical correction of all uterine defects is not so necessary for a successful outcome of pregnancy.

Adult↗

[Evaluation of combined application of diazepam, fenoterol and metamizole in prevention of uterine-tubal spasm during the performance of hysterosalpingography].

In the years from 1989 to 1991 HSG examination was carried out in 502 infertile women. Two hours before the examination 5 mg of diazepam and 5 mg of fenoterol were orally administered, and 30 minutes prior to the procedure 2.5 mg of metamizole were given intramuscularly. The examined population of women was found to have normal patency of oviducts in 412 (82.07%) women, 48 (9.56%) had uni- or bilateral impatency of abdominal openings, in 16 (3.19%) there was uni- and in 19 (3.78%) bilateral +impatency of oviducts in uterine segments, while in 7 (1.39%) alternating impatency was disclosed. Of 502 women in 109 patients laparoscopy and chromotubation were performed during a period from 2 to 16 months after HSG examinations. In 30 (93.7%) out of 32 women with impatency of oviducts in the proximal segment, the diagnosis was confirmed. The administered drugs effectively prevent uterine-tubal spasms occurring at the time HSG is being accomplished.

Diazepam↗

Primary carcinoma of the fallopian tube mimicking tubo-ovarian abscess.

PURPOSE: The aim of the study is to report that the primary fallopian tube cancer can be presented as a tubo-ovarian abscess preoperatively. METHODS: A patient with a preoperative diagnosis of a tubo-ovarian abscess with abdominal pain, tenderness and an elevated fever with leukocytes underwent urgent exploratory laparotomy. RESULTS: Explorative laparotomy and accompanied frozen section revealed a right-sided tubal carcinoma. There was an inflammatory and purulent reaction in the tube that was adherent to the anterior uterus. Total hysterectomy and bilateral salpingo-oophorectomy were performed. CONCLUSION: Carcinoma of the fallopian tube should be considered in the differential diagnosis of acute pelvic peritonitis like a tubo-ovarian abscess.

Abdominal Abscess↗

Isolated tubal torsion: a rare cause of pelvic pain at menarche. Sonographic and MR findings.

Isolated torsion of the fallopian tube is a rare clinical entity, especially in adolescents and at menarche. The diagnosis is essentially made at laparoscopy or at laparotomy because of nonspecific clinical signs. We present a case of isolated tubal torsion in a 12-year-old girl a few days after menarche, highlighting the sonographic and MR findings. Both techniques demonstrated the enlarged and tortuous fallopian tube with normal ovaries and uterus, but MR was also able to characterize contained blood and absent vascular supply. Although this condition is uncommon it should be considered as a cause of acute pelvic pain in adolescents because of the possibility of salvage surgery with early diagnosis. Sonography and MRI have a complementary role in this diagnosis.

Child↗

Late results of salpingostomy combined with salpingolysis and ovariolysis by electromicrosurgery in 54 women.

In 1975 and 1976 all together 54 women were treated with electromicrosurgery for correction of infertility due to peritubal and periovarian adhesions combined with sactosalpinx. Besides the gentle and less traumatic microsurgical method, corticosteroids combined with oxyphenbutazone were given to prevent new adhesions. Hydropertubation was performed on the 2nd and 4th postoperative days. Twenty-one (39%) of the patients became pregnant, 4 of them twice. Out of the 21 patients, 17 gave birth to live children, while in 3 of the 21 patients spontaneous abortion occurred. One legal abortion was performed. No ectopic pregnancies were observed in this unselected material.

Adult↗

Mucosal epithelial proliferation of the fallopian tube: prevalence, clinical associations, and optimal strategy for histopathologic assessment.

The prevalence and clinical significance of mucosal epithelial proliferation or hyperplasia of the fallopian tube are controversial in the few studies reported. Some authors have retrospectively examined "routine" sections (one or two submitted from each tube), whereas others have prospectively blocked the entire tubes. In the current study, we prospectively studied a total of 168 tubes from 98 women who had various indications for salpingectomy and compared the diagnosis in an initial single section (to simulate the usual practice) with that in the remainder of the entirely sectioned and submitted tube (mean total number of sections, 9.0). Some degree of mucosal epithelial proliferation was found in 83% of all tubes examined, with no difference between the tubes removed for routine tubal ligation and those in women who had benign ovarian lesions, malignant gynecologic tumors, uterine leiomyomata, or benign tubal lesions (salpingitis or ectopic pregnancy). Mucosal epithelial proliferation graded as more than mild, however, was seen in only 4.5% of the otherwise normal ligated tubes versus 35 to 46% of tubes associated with the other lesions. When the initial sections were compared with the subsequent ones, the diagnosis was identical in 96 tubes (57%). In the other 72 tubes (43%), the difference in diagnosis was never greater than one grade (no, mild, moderate, severe mucosal epithelial proliferation), with the diagnosis more often upgraded (50 tubes) than downgraded (22 tubes) in the additional sections. It is concluded that there is no reason to submit an entire tube for histologic examination to detect clinically significant lesions, and the usual practice of submission of one or two sections is clinically appropriate.

Cell Division↗

Torsion of the fallopian tube during pregnancy.

We describe 3 cases of torsion of the Fallopian tube during pregnancy, caused by sactosalpinx, a cyst of the mesosalpinx, and an ovarian cyst. Other causes of torsion of the Fallopian tube are discussed. The difficulty of diagnosing this condition during pregnancy is emphasized.

Adult↗

[Hysterosalpingography combined with hysteroscopy-laporoscopy in diagnosing female infertility].

OBJECTIVE: To evaluate hysterosalpingography (HSG) combined with hysteroscopy-laparoscopy in diagnosing female infertility. METHODS: One hundred thirty three female infertile patients by clinical diagnosis were given HSG and hysteroscopy-laparoscopy, and the results were retrospectively analyzed. RESULTS: The total diagnostic coincidence rate of the two methods in diagnosing uterus-cervix infertility was 80.2%, while the coincidence rate of the two methods in diagnosing tubal infertility was 89.7%. CONCLUSION: HSG combined with hysteroscopy-laparoscopy is an optimal method in diagnosing female infertility at present.

Adult↗

[Epidural anesthesia with morphinomimetics in gynecologic operations].

Epidural anesthesia with injection of morphinomimetics into the epidural space was used in 181 patients during gynecologic surgery. The advantages of this type of anesthesia over the endotracheal one consist in reduction of the incidence of complications during the operation and after it.

Adolescent↗

[Cost effective media in vaginal ultrasound uterus and fallopian tube diagnosis].

AIM: The recent development of hysterocontrastsonography (HyCoSy) for assessing tubal patency may provide an alternative to current methods, which are either invasive (laparoscopy and dye) or involve exposure to radiation and require a radiology department (hysterosalpingography). METHOD: Following the introduction of an intrauterine balloon catheter, the contrast agent (Echovist) is slowly injected into the cavity and tracked using ultrasound as it passes through the tubes. The technique is well tolerated as an outpatient method, and takes about 15 to 20 minutes to perform. RESULTS: In a clinical trial with infertile women we compared the results of HyCoSy to laparoscopy and dye. In 90 out of 108 tubes investigated the results agreed-equivalent to a sensitivity of 88% and a specificity of 82%. Three false negative findings on the one hand and 15 false positive findings on the other represent a negative predictive value of 96% and a positive predictive value of 58%. In approximately 50% of patients, this outpatient procedure caused little or no pain, and in 40%, moderate pain. Only a small part of the investigated group (8%) complained about serious discomfort; in two cases (3%) the procedure was discontinued because of pain. CONCLUSION: HyCoSy is a reliable and simple method to provide preliminary information about tubal patency. It may be carried out at an early stage of the algorithm to investigate the infertile couple, and may so lead to more rapid and efficient treatment.

Adult↗

Hysterosalpingography: a reemerging study.

Hysterosalpingography (HSG) has become a commonly performed examination due to recent advances and improvements in, as well as the increasing popularity of, reproductive medicine. HSG plays an important role in the evaluation of abnormalities related to the uterus and fallopian tubes. Uterine abnormalities that can be detected at HSG include congenital anomalies, polyps, leiomyomas, surgical changes, synechiae, and adenomyosis. Tubal abnormalities that can be detected include tubal occlusion, salpingitis isthmica nodosum, polyps, hydrosalpinx, and peritubal adhesions. Some complications can occur with HSG-most notably, bleeding and infection-and awareness of the possible complications of HSG is essential. Nevertheless, HSG remains a valuable tool in the evaluation of the uterus and fallopian tubes. Radiologists should become familiar with HSG technique and the interpretation of HSG images.

Fallopian Tube Diseases↗

The role of hysterosalpingography in modern gynaecological practice.

A retrospective review of hysterosalpingography (HSG) in a major gynaecological centre was carried out. 324 patients attended (95%) for HSG out of 341 patients referred for this investigation. 189 examinations (58.3%) were abnormal. The requests and radiological findings were reviewed and the results compared with laparoscopy. HSG remains an integral part of gynaecological investigation and its value has not diminished in modern practice.

Adult↗