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At least 91 records · Page 5Linked to original sources
PubMed2000

[Dynamic magnetic resonance tomography (MRI): a follow-up study after femur core decompression and instillation of recombinant human bone morphogenetic protein-2 (rhBMP-2) in avascular femur head necrosis].

OBJECT: The aim of the study was to test the use of dynamic magnetic resonance imaging study with Gd-DTPA-application and the dynamic changes of signal intensity at patients with avascular femoral head necrosis after having installed rhBMP-2 and/or decompressed the core. MATERIAL AND METHODS: Six patients with avascular necrosis of the femoral head ARCO-stage I- or II-lesions were treated surgically by femoral head core decompression. Three of these patients were additionally treated with rhBMP-2-instillation. The progression or regression could be confirmed by T1- and T2-weighted spinecho-sequences (zero, four, ten, sixteen weeks and 24 months follow up). RESULTS: Corresponding ARCO-classification with partly more sensitive measurement of vitality signs in comparison to the optical x-ray classification. The objective, quantitative measurement of signal intensity post contrast medium reduces the influence of experience and level of education. The dynamic sequences results are reproducible. CONCLUSION: The dynamic magnetic resonance imaging study after Gd-DTPA-application and the dynamic changes of signal intensity after Gd-DTPA enhancement in the necrotic areas of the femoral head were the important subject of our study and it seems, that these sequencies and the ascertainment of signal intensity changes will be an efficient method for judgement of vitality, vascularisation and perfusion after therapeutical intervention. Combination of femoral head core decompression and rhBMP-2-instillation for the purpose of osseous regeneration seems to stabilize the affection.

Adult↗
PubMed1987

[Distribution of haversian remodeling in the human femur by an osteon count. A study of 6 femurs in cadavers].

To estimate the remodelling of diaphyseal compact bone in the femora of five subjects aged between 63 and 83 years, osteons and osteon fragments were counted. The measurements were made from microradiographs of transverse sections at all levels in the diaphysis. The ventral, dorsal, lateral and medial quadrants were considered separately. The mean osteon count was uniform in all quadrants and at all levels in the proximal two-thirds of the diaphysis, but tended to be less in the distal third. In addition, there were nearly always more osteons, complete and fragmented, per square millimetre in the subperitoneal region than in the neighbourhood of the medullary cavity. In older subjects, there does not seem to be a relationship between the remodelling of femoral compact bone and the specific mechanical stresses in each diaphyseal quadrant.

Aged↗