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PubMedDate not supplied

Directory of education.

One of the most important tools to career building and personal satisfaction is education. And there are a wide variety of ways for you to get it. Some are available through your professional associations (see the "Directory of Associations" for more information on those), others are available through correspondence courses, on-site courses at local colleges, and from seminar programs of associations, vendors and seminar groups and still others are available in audiovisual formats. We've assembled a list of educational offerings that should be of interest to you and your colleagues. There may be others offered in your area, so contact your local institutions of higher learning to take advantage of what they have--or to develop a course with them!

Central Supply, Hospital↗
PubMedDate not supplied

Directory of education.

One of the most important tools to career building and personal satisfaction is education! And there are a wide variety of ways for you to get it. Some are available through your professional associations (see the "Directory of National Associations" for more information on those), others are available through correspondence courses, on-site courses at local colleges and universities, seminar programs of associations, vendors and seminar groups, and still others are available in audiovisual formats. We've assembled a list of educational offerings that should be of interest to you and your colleagues. There may be others offered in your area, so contact your local institutions of higher learning to take advantage of what they have--or to develop a course with them!

Central Supply, Hospital↗
PubMedDate not supplied

Directory of resources.

This directory contains almost 300 entries of publications, publishers, electronic informational sources, professional association and consultants that all provide pertinent information for the healthcare material manager, central service personnel and others charged with managing healthcare equipment, supplies and services.

Books↗
PubMed2004

[Construction of directory for biomedical databases on INTERNET].

OBJECTIVE: To construct a global directory of biomedical databases(DBD), which can be used free of charge on INTERNET. It will be convenient for researchers to find out related databases quickly, easily and accurately by using DBD since there are not enough useful tools for database retrieval. Biomedical databases will be an accelerator in development of biomedicine with the help of DBD. METHODS: PubMed and Google were main tools for searching related databases. Proper search strategy with rigorous indexing rules helped us to filter databases. The database management system was Microsoft SQL-Server 2000. The web pages of DBD were designed with Macromedia Dreamwaver MX. ASP (active server pages) technology was used to deal with the key words and scores sent by users. RESULTS: There were 66 subjects and 1 258 databases in DBD at this time. We released the Chinese and English versions of DBD on the INTERNET at the same time http://cmbi.bjmu.edu.cn/DBList/index.htm http://cmbi.bjmu.edu.cn/DBList/index_en.htm . Score system was also established to evaluate the content of the indexed databases. Users can search DBD by subjects key words and alphabetic databases' names easily. CONCLUSION: DBD has laid the primary foundation for further core biomedical database evaluation system. DBD, as a useful tool for biomedical database retrieval, will be of great aid to users since databases have played a more and more important role in the biomedical research.

Databases as Topic↗
PubMed1992

Directory of registries of clinical trials.

Registries of clinical trials are a potentially useful resource for the planning of new studies, the promotion of communication and collaboration between researchers, the conduct of meta-analyses, and the facilitation of patient access and recruitment to trials. However, many physicians and researchers are unaware of their existence, and as a result they remain underused. A directory of registries of clinical trials has been developed as a result of an international survey of 63 organizations and 51 individuals in 13 different countries to identify the existence of such registries. This is intended as a resource to keep physicians, researchers, trial organizers, funding bodies and government agencies abreast of the growing number of registries available, and to assist in the planning of future registries. Twenty-four current and six planned registries of clinical trials have been identified. Most focus on AIDS or oncology, but such diverse areas as neurosurgery, cardiovascular disease, dentistry and perinatology are also represented. This paper presents a descriptive profile on each registry and discusses the relative merits of their different organizational features. Recommendations are given for the establishment of future registries.

Clinical Protocols↗
PubMed1990

Telephone directory listings of presumptive Chinese surnames: an appropriate sampling frame for a dispersed population with characteristic surnames.

Choosing an appropriate sampling frame for an epidemiologic study depends on the characteristics of the population under investigation and the sources available for identification of potential subjects. Not all countries maintain (or permit sampling from) population registers. In studies of dispersed populations, electoral rolls may lead to sampling bias, and random-digit dialing is inefficient. A dispersed population characterized by distinctive surnames might be appropriately identified and sampled through telephone directory listings, however. The method proved feasible and efficient for a prevalence study of health-related characteristics of Chinese residents in Melbourne, Australia, yielding a sample demographically comparable to the corresponding census population.

Adult↗
PubMed1994

A directory of human germ-line V kappa segments reveals a strong bias in their usage.

From the genomic DNA of a single individual, we have amplified, cloned and sequenced 37 human germ-line V kappa segments. Four of these segments were new. We then compiled a comprehensive directory of all germ-line V kappa segments and identified 50 different sequences with open reading frames. Comparison with 236 rearranged sequences revealed that no more than 24 of these germ-line sequences could be assigned rearranged counterparts, that some of these were rarely used, and that only about 11 sequences are used frequently. This suggests that the expressed V kappa repertoire is mainly derived from a limited number of segments. Most surprisingly, the J kappa-distal region of the locus appears to be rarely used: we could unambiguously assign 162 rearranged sequences to V kappa segments of the J kappa-proximal region, but only 5 to segments of the J kappa-distal region.

Amino Acid Sequence↗
PubMed1994

On the use of LUDI to search the Fine Chemicals Directory for ligands of proteins of known three-dimensional structure.

It is shown that the computer program LUDI can be used to search large database of three-dimensional structures for putative ligands of proteins with known 3D structure. As an example, a subset of approximately 30,000 small molecules (with less than 40 atoms and 0-2 rotatable bonds) from the Fine Chemicals Directory has been used in the search for possible novel ligands for four different proteins (trypsin, streptavidin, purine nucleoside phosphorylase and HIV protease). For trypsin and streptavidin, known ligands or substructures of known ligands are retrieved as top-scoring hits. In addition, a number of new interesting structures are found in all considered cases. Therefore, the method holds promise to retrieve automatically protein ligands from a 3D database if the 3D structure of the target protein is known.

Bacterial Proteins↗
PubMed1995

Development of a directory of genetic probes as a shared institutional resource.

This report describes design and implementation of a genetic probe directory database for use by researchers in a medical school. The purpose of the database is to allow researchers to exchange descriptive information concerning probes available in their laboratories in order to facilitate collaboration. The Genetic Probe Database Browser (GPDB) allows multi-field constraints and wildcard searchers of the database, e-mail upload and download of data, and provides simple database administrator tools. The GPDB is implemented in C under the UNIX operating system, and uses the 'Curses' character terminal package to provide access to users unable to use modern graphical user interfaces. Currently, 10 researchers have contributed approximately 250 genetic probes, and several research collaborations have been started because of this resources.

DNA Probes↗
PubMed1998

The European Directory of Burns Research.

The European Directory of Burns Research is a database of research activity in Europe. This ongoing database, established under the auspices of the Research Committee of the European Burns Association (EBA), provides basic information on research studies in progress or completed. The first issue, for the period 1995/1996, present information received after return of 118 questionnaires from researchers working in 27 countries in Europe and its close neighbours. This is not a large number of responses and may reflect problems with access to groups working in burns, but ignorant of the request for information on research activities. The aim is to maintain and update the database annually through distribution and return of a simple questionnaire. Information will be available to EBA members on request but the accuracy and detail of the database will ultimately be influenced by the co-operation of the burns research community.

Animals↗
PubMed2006

Identification of novel parasitic cysteine protease inhibitors by use of virtual screening. 2. The available chemical directory.

The incidence of parasitic infections such as malaria, leishmaniasis, and trypanosomiasis has been steadily increasing. Since the existing chemotherapy of these diseases suffers from lack of safe and effective drugs and/or the presence of widespread drug resistance, there is an urgent need for development of potent, mechanism-based antiparasitic agents against these diseases. Cysteine proteases have been established as valid targets for this purpose. The Available Chemical Directory consisting of nearly 355,000 compounds was screened in silico against the homology models of plasmodial cysteine proteases, falcipain-2, and falcipain-3, to identify structurally diverse non-peptide inhibitors. The study led to identification of 22 inhibitors of parasitic cysteine proteases out of which 18 compounds were active against falcipain-2 and falcipain-3. Eight compounds exhibited dual activity against both enzymes. Additionally, four compounds were found to inhibit L. donovani cysteine protease. While one of the cysteine protease inhibitors also exhibited in vitro antiplasmodial activity with an IC50 value of 9.5 microM, others did not show noticeable antiplasmodial activity up to 20 microM. A model identifying important pharmacophoric features common to the structurally diverse falcipain-2 inhibitors has also been developed. Very few potent non-peptide inhibitors of the parasitic cysteine proteases have been reported so far, and identification of these novel and chemically diverse inhibitors should provide leads to be optimized into candidates to treat protozoal infections.

Animals↗
PubMed2003

Using commercial telephone directories to obtain a population-based sample for mail survey of women of reproductive age.

In the United States, sampling women of reproductive age from the general population for research purposes is a challenge. Even more difficult is conducting a population-based study of couples attempting pregnancy to assess fecundity and fertility or related impairments. To address the problem of obtaining representative samples from the population in order to study such health-related issues, a commercially and readily available CD-ROM telephone directory was used and tested as a sampling framework for studies aimed at enrolling gravid women aged 18-44 years. A self-administered questionnaire (SAQ) was mailed to a stratified random sample of 10 005 (3%) households in Erie County, NY, USA. Overall, 17% of the questionnaires were undeliverable despite updating all addresses with residential software before mailing. Thirteen per cent (n = 1089) of the households returned completed questionnaires, of which 35% (n = 377) were completed by women aged 18-44 years. Using 1990 census information for zip code, respondents were more likely to be white and to have higher median household incomes than non-respondents. Of the 377 women who completed the questionnaire, 79% had been pregnant at least once, 5% reported being unable to become pregnant, and 16% reporting never trying to become pregnant. Despite the overall low response to the SAQ, the sampling framework captured a diverse group of women of reproductive age who reported various fecundity and fertility outcomes. The use of low-cost commercially available software linked to census data for selecting samples of women or couples for reproductive and perinatal research may be possible; however, oversampling of households, use of incentives and follow-up of non-respondents is needed to ensure adequate sample sizes.

Adolescent↗
PubMed1994

The effect of different work-rest schedules on fatigue and performance of a simulated directory assistance operator's task.

The directory assistance operators' task with a visual display terminal was simulated to determine the preferable work-rest schedule from among the three different work-rest schedules: 30 min of work followed by 5 min break (30-5); 60 min of work followed by 10 min break (60-10); and 120 min of work without any break (120-0). The total working duration was 2 h. The errors made during the work and the subjective responses before and after the working period (2 h) were recorded and analysed. The results showed that the first two work-rest schedules were preferable to the third condition (120-0) as significantly fewer errors were made (p > or = 0.01) when a short break was provided. There was no significant difference (p > or = 0.10) in errors between (30-5) and (60-10) schemes. Fewer before and after subjective responses differed significantly for (30-5) and (60-10) schemes than for the (120-0) scheme. The overall effect of schemes on subjective responses, however, was not statistically significant at the 5% level. Since both (30-5) and (60-10) schemes were found acceptable, the (60-10) scheme is recommended since it is easy to implement, causes fewer breaks and therefore, fewer work interruptions, and leads to fewer total minutes of break.

Adolescent↗
PubMed1996

The directory of P450-containing systems on WorldWide Web.

To facilitate access to electronic resources for all researchers working in the field of P450 proteins and P450-containing systems, a WorldWide Web server has been established called The Directory of P450-containing Systems at < http://www.icgeb.trieste.it/p450/ >. Currently it contains the most up-to-date list of sequences of both the P450 superfamily and proteins mediating electron transfer to P450, i.e. NADPH:P450 reductases, specific NAD(P)H:ferredoxin reductases, cytochrome b5 reductases, ferredoxins and cytochromes b5, and their homologues from different enzyme systems. All the referenced sequences are provided with accession numbers and cross-links to major sequence databanks: PIR, SWISS-PROT, EMBL/GenBank and PRF.

Amino Acid Sequence↗
PubMed1997

The directory of P450-containing systems in 1996.

The Directory of P450-containing Systems on WorldWide Web has been designed to facilitate access to electronic resources for all researchers working in the field of P450-containing and related enzyme systems. Currently, it contains the most up-to-date list of sequences of both the P450 superfamily and proteins mediating electron transfer to P450, i.e. NADPH:P450 reductases, specific NAD(P)H:ferredoxin reductases, cytochromeb5 reductases, ferredoxins and cytochromesb5, and their homologues. All the referenced sequences are provided with accession numbers and links to major sequence databanks: PIR, SWISS-PROT, EMBL/GenBank and PRF. An associated database of steroid substrates and products of P450-dependent reactions has also been developed.

Amino Acid Sequence↗
PubMed2005

Scaling in the structure of directory trees in a computer cluster.

We describe the topological structure and the underlying organization principles of the directories created by users of a computer cluster. Users create trees with a scale-free degree distribution whose properties are reproduced by a growth and preferential attachment mechanism with a single parameter. The degree distribution has a nonuniversal exponent associated with different values of the parameter. However, the distribution of branch sizes has a universal exponent analytically obtained from the model.

Journal Article↗
PubMed2006

Does sampling using random digit dialling really cost more than sampling from telephone directories: debunking the myths.

BACKGROUND: Computer assisted telephone interviewing (CATI) is widely used for health surveys. The advantages of CATI over face-to-face interviewing are timeliness and cost reduction to achieve the same sample size and geographical coverage. Two major CATI sampling procedures are used: sampling directly from the electronic white pages (EWP) telephone directory and list assisted random digit dialling (LA-RDD) sampling. EWP sampling covers telephone numbers of households listed in the printed white pages. LA-RDD sampling has a better coverage of households than EWP sampling but is considered to be more expensive due to interviewers dialling more out-of-scope numbers. METHODS: This study compared an EWP sample and a LA-RDD sample from the New South Wales Population Health Survey in 2003 on demographic profiles, health estimates, coefficients of variation in weights, design effects on estimates, and cost effectiveness, on the basis of achieving the same level of precision of estimates. RESULTS: The LA-RDD sample better represented the population than the EWP sample, with a coefficient of variation of weights of 1.03 for LA-RDD compared with 1.21 for EWP, and average design effects of 2.00 for LA-RDD compared with 2.38 for EWP. Also, a LA-RDD sample can save up to 14.2% in cost compared to an EWP sample to achieve the same precision for health estimates. CONCLUSION: A LA-RDD sample better represents the population, which potentially leads to reduced bias in health estimates, and rather than costing more than EWP actually costs less.

Adolescent↗
PubMed2002

Logistical aspects of large telemedicine networks. 1: Site directories.

We carried out a survey of the site coordinators in a mature telemedicine network of about 200 sites. The site directory contained information about 221 videoconference facilities. There were 191 site coordinators in all (i.e. some coordinators were responsible for more than one site). Of the 221 sites, we were able to contact 87 on first attempt and 155 by the fourth attempt. Thus there were 66 sites (30%) which were not contactable. We asked each site coordinator to describe any videoconference activity that had taken place over the previous five working days. Of the contacted 155 sites, 78 reported some videoconference activity during the period in question. The total reported videoconference activity was 12,800 min during the one-week monitoring period, that is, an estimated 924 h per month. The most common categories of work were education or training (511 h) and management or administration (225 h), which between them accounted for 80% of all reported videoconference activity. Fifty of the 155 sites (32%) reported that the equipment was not located in an area suitable for patient consultations. In addition, 20 sites (13%) volunteered that their videoconferencing facilities were not in working order at the time of the survey. We did not ask this question in the survey, so that this result represents a lower bound for the true number of inoperable systems.

Journal Article↗