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At least 91 records · Page 5Linked to original sources
PubMed1999

[A study of aggravation of atopic dermatitis during Japanese cedar pollen season--correlation with grades of dermatitis on face and Cry j 1 specific IgE].

We studied influence of Japanese cedar pollen (Jcp) on aggravation of atopic dermatitis (AD) during the pollination season. 48.5% of 97 patients with atopic dermatitis showed aggravation of dermatitis during the pollination season and 85% of them had Japanese cedar pollinosis, whereas only 44% of AD patients without the aggravation had the pollinosis. There was no difference of grades of dermatitis on face between the groups with or without the aggravation. Furthermore, we measured specific IgE to Jcp and Cry j 1, a major allergen of Jcp, by ELISA in the sera from the 54 patients with AD. The levels of specific IgE antibodies to both allergens in the group with the pollinosis were significantly higher than in the group without the pollinosis. However, significant difference of those was not recognized between the groups with or without the aggravation of AD. Therefore, our study has suggested that Japanese cedar pollen is likely to be one of causes of seasonal aggravation of AD in individuals sensitized to the pollen, and some other factors, e.g. Jcp-specific T cells, might play an important roll in addition to the Jcp-specific IgE.

Adolescent↗
PubMed1990

[The role of bacteria on facial rosacea-like dermatitis in adult type atopic dermatitis].

To investigate the role of bacteria on facial rosacea-like dermatitis lesion in adult type atopic dermatitis, we measured the numbers of bacteria on the skin, nasal and pharyngeal surface of each individual, and then examined its sensitivity to antibiotics. The numbers of bacteria on the surface of skin increased according to the severity of skin eruption. Staphylococcus aureus was detected from the skin and nasal surface more than pharyngeal surface. Bacteria on the pharyngeal surface were both staphylococcus aureus and haemophilus parainfluenzae. Therefore, it is suggested that bacterial flora on the pharynx is different from those of the skin and nose. The treatment with antibiotics was effective for exudative lesions, whereas lichenified lesion did not respond to antibiotic therapy. These results suggest that bacteria on the skin surface are one of precipitating factors of the rosacea-like dermatitis of atopic dermatitis.

Adolescent↗
PubMed1981

Seborrhoeic dermatitis and napkin dermatitis.

Seborrhoeic dermatitis is described clinically and histologically with emphasis upon the vague definition of the disease. The relationship between pityriasis asteatosa and psoriasis is discussed. Napkin dermatitis is subdivided into infantile seborrhoeic dermatitis and true napkin dermatitis. The relationship between the former and psoriasis is unsettled. The role of microorganisms is stressed. Granuloma gluteale infantum is a condition caused by potent topical steroids and C. albicans.

Adrenal Cortex Hormones↗
PubMed1980

[Postovulation dermatitis (dermatitis caused by progesterone)].

Postovulation Dermatitis is a frequent clinical picture although it is not well known. Clinically a polymorphous eruption appears between than 8 or 10 day before menses. The Authors report three cases in which an complete immunological investigation was performed. They conclude that there is no objective evidence of the autoimmune pathogeny of this picture in spite of the clinical relationship between the dermatitis and the ovulation. Therefore they suggest that diseases should be described as "Postovulation Dermatitis" instead "Autoimmune Progesterone Dermatitis".

Adult↗
PubMed1995

[The correlation between the levels of anti-Malassezia furfur IgE antibodies and severities of face and neck dermatitis of patients with atopic dermatitis].

It is well known that the seborrheic areas including the face and neck of patients with atopic dermatitis (AD) are frequently affected after adolescence. Malassezia furfur (MF), a lipophilic yeast and a normal habitat of seborrheic areas, has been thought to be one of the most important factors in provoking face and neck lesions of AD. In the present study, we assessed serum levels of anti-MF IgE antibodies by enzyme-linked immunosorbent assay (AlaSTAT method) in 123 adolescent and adult AD patients and evaluated the correlations between levels of anti-MF IgE and those of total IgE and some other allergen-specific IgE. The correlation between the levels of anti-MF IgE and severities of face and neck dermatitis was also assessed. Anti-MF IgE antibodies were detected in high frequency in AD patients (77%), while they were not found in controls. Significant correlations were noted between the levels of anti-MF IgE and those of total IgE and anti-Candida IgE. The levels of anti-MF IgE were well correlated with the severities of face and neck dermatitis. These result may indicate that MF is an important provocative factor for face and neck dermatitis in AD patients.

Adolescent↗
PubMed1984

Effect of several dermatitis preventing agents on foot pad dermatitis in dwarf and normal sized single comb white Leghorn layers.

Studies were conducted to determine the effects of increased dietary levels of vitamin and trace mineral mixtures, methionine, meat and bone meal, fish meal, and safflower oil on foot pad dermatitis in dwarf and normal size Single Comb White Leghorn layers. All layers were maintained in individual wire cages throughout a 40-week experiment period. Individual birds were scored for the incidence of foot pad dermatitis and production parameters were recorded. No significant decrease in the incidence of dermatitis was observed from the following dietary supplements: a 50% increase in a vitamin or a complete trace mineral mixture; a 50% increase in an iron, copper, iodine, and cobalt or a manganese and zinc mixture; .05% methionine; 5% meat and bone meal; 3% herring fish meal; or 2% safflower oil. It was concluded that these mixtures or supplements containing such dermatitis preventative agents as pantothenic acid, zinc, and linoleic acid appeared without effect in minimizing expression of the condition in dwarfs.

Animals↗
PubMed1990

IgE-positive epidermal Langerhans cells in allergic contact dermatitis lesions provoked in patients with atopic dermatitis.

To see whether or not IgE-bearing epidermal Langerhans cells are specific to skin lesions of atopic dermatitis (AD), we performed immunohistochemical and immunoelectron microscopic examinations of dinitro-chlorobenzene (DNCB) contact dermatitis lesions provoked in uninvolved skin of eight patients with AD. In all of the eight examined, IgE-positive epidermal Langerhans cells were observed in the DNCB dermatitis lesions. Typical staining of anti-IgE was absent in the epidermis of normal-appearing skin of five patients with AD. Thus, it is likely that IgE positive epidermal Langerhans cells non-specifically occur in different eczematous diseases provoked in patients with AD.

Adolescent↗
PubMed1983

Pruritic dermatitis in asthmatic basenji-greyhound dogs: a model for human atopic dermatitis.

A recurrent, nonseasonal pruritic dermatitis manifested as lichenified plaques and as inflammatory nodules and papules in each of fourteen basenji-greyhound (B-G) crossbreed dogs, all of which demonstrated both nonspecific and Ascaris-specific airway hyperreactivity, with changes in pulmonary mechanics of the same order as those seen in symptomatic human asthma. Other features analogous to human atopic disease included blunted cyclic adenosine monophosphate (cAMP) responsiveness to beta adrenergic agents and in vivo release of histamine and slow-reacting substance of anaphylaxis in response to antigen aerosol challenge. The dermatitis appears to be a manifestation of the atopic state in these dogs and may provide an animal model for the study of human atopic dermatitis.

Animals↗
PubMed1987

Occupational dermatitis in bakers: a clue for atopic contact dermatitis.

6 patients are described who developed contact dermatitis after cereal contact on atopic skin for periods of 2 to 20 years. 2 patients were wheat flour patch-test-positive. They had punch biopsies taken for standard histological and immunohistochemical investigation by labeling with monoclonal antibodies, anti-DR and anti-IgE. Sections showed features of contact dermatitis. There were many dendritic cells located perivascularly in the papilla and in the epidermidis, intensely positive for monoclonal anti-IgE antibody. In control atopic subjects, there were a few perivascular IgE positive cells, probably mastocytes. This study shows that there may be a relationship between some allergens and atopic eczema in patients exposed to them in the course of their work. In some cases, there was a true allergic contact dermatitis, seen through the clinical and histological characteristics, and the results of immunohistochemical study.

Adult↗
PubMed1987

Contact dermatitis in Nigeria (i). Hand dermatitis in women.

Of 545 consecutive contact dermatitis clinic patients, 271 (49.7%) were women, 29 (10.7%) of whom had hand dermatitis alone. 17 (58.6%) of these hand cases were allergic, the main sensitizers being nickel and essential oils in oranges. Dress makers were mostly affected by nickel, while orange sellers and peelers were positive to orange peel, fragrance mix, balsam of Peru and formaldehyde in varying combinations. 8 (27.6%) of the hand cases were due to irritants and wet jobs, and possibly to allergens not tested. 24 (83%) of the hand cases were occupational. Only 1 Nigerian woman had true housewife's hand dermatitis. It was not possible to define the rôle of atopy because of unreliable histories. 2 cases of pompholyx and a negative patch test occurred in the first trimester of pregnancy.

Adolescent↗
PubMedDate not supplied

Allergen specificity and endothelial transmigration of T cells in allergic contact dermatitis and atopic dermatitis are associated with the cutaneous lymphocyte antigen.

Recent investigations have indicated a role for antigen-specific T lymphocytes in the local skin immunity. The cutaneous lymphocyte antigen (CLA) is supposed to represent a skin-homing receptor for T cells. Inhibition experiments with specific monoclonal antibody demonstrate that CLA participates in selective transendothelial migration of memory/effector T cells in vitro by interaction with E-selectin on endothelial cell layers after activation with proinflammatory cytokines. In addition, the receptor-ligand pairs VLA-4/VCAM-1 and LFA-1/ICAM-1 are involved in this process. Moreover, only CLA+, CD45RO+ (memory/effector) T cells freshly isolated from peripheral blood of patients with allergic contact dermatitis or atopic dermatitis specifically proliferate in response to the respective allergen. CLA-, CD45RO- T cells from these patients do not respond to the allergens. In contrast, memory T cells from asthmatic individuals and patients with both asthma and atopic dermatitis express the allergen specificity in both T cell subsets. Tetanus toxoid, a systemically acting antigen, also induces a proliferative response in both CLA+ and CLA- memory/effector T cell subsets. These results strongly support the selective role of CLA in homing T cells to the cutaneous tissues and therefore playing a role in the local immunity and inflammatory reactions of the skin.

Adult↗
PubMed1995

Contact dermatitis to biperiden and photocontact dermatitis to phenothiazines in a pharmacist.

A case of contact dermatitis to biperiden, an anti-Parkinson agent, and photocontact dermatitis to phenothiazines in a pharmacist was reported. The patient developed eczematous lesions on exposed area after she had worked at a psychiatric hospital for 6 months. She showed positive patch test reaction to biperiden. In addition, she reacted positively to photopatch testing with ultraviolet A and phenothiazines such as chlorpromazine and perphenazine. To our knowledge, contact dermatitis to biperiden has not been previously reported in the English literature.

Biperiden↗
PubMed2003

Contact urticaria, allergic contact dermatitis, and photoallergic contact dermatitis from oxybenzone.

There is little literature regarding conventional patch tests and photopatch tests to oxybenzone resulting in both immediate- and delayed-type hypersensitivity reactions. A patient was patch-tested and photopatch-tested to various sunscreen chemicals. Both immediate- and delayed-type hypersensitivity reactions were observed with oxybenzone. The positive patch tests were also photoaccentuated. Oxybenzone, a common sunscreen allergen, can result in both contact urticaria and delayed-type hypersensitivity on both conventional patch testing and photopatch testing. Allergic contact dermatitis to sunscreen chemicals has traditionally included contact urticaria, allergic contact dermatitis, and photoallergic contact dermatitis. Due to the recognition of p-aminobenzoic acid (PABA) and its esters as sensitizers, the presence of benzophenones in "PABA-free" sunscreens has become more prevalent, especially in sunscreens with a sun protection factor (SPF) greater than 8. In our patient, immediate- and delayed-type hypersensitivity reactions were seen to oxybenzone (2-hydroxy-4-methoxybenzophenone, 2-benzoyl-5-methoxyphenol, benzophenone-3, Eusolex 4360, Escalol 567, EUSORB 228, Spectra-Sorb UV-9, Uvinul M-40) upon conventional patch testing and photopatch testing.

Allergens↗
PubMedDate not supplied

Allergic contact dermatitis in patients with atopic dermatitis: A clinical study.

BACKGROUND: Atopic dermatitis (AD) is a chronically relapsing dermatitis with no known cure. Due to the chronic nature of the condition, frequent and long term topical therapy is used. This may lead to sensitization, resulting in allergic contact dermatitis (ACD). AIMS: The aim of the study was to observe the frequency of ACD in atopic patients in this part of the country using Indian standard battery. METHODS: A total number of 30 cases of AD were taken for the study. Diagnosis of AD cases was based on the criteria of Hannifin and Rajka (1980). All the selected cases of AD had mild to moderate grade of severity. All these cases were treated and patch tested during the remission period. The duration of the study was 12 months. RESULTS: Out of the 30 AD cases, 7 cases showed positive ACD with patch test allergens. CONCLUSION: This study shows that ACD is not uncommon amongst atopic individuals.

Adolescent↗
PubMed2002

Allergic contact dermatitis from transdermal estradiol and systemic contact dermatitis from oral estradiol. A case report.

BACKGROUND: About 20% of patients using transdermal estradiol complain of adverse local side effects. CASE: A 47-year-old, postmenopausal woman developed eczematous lesions at the sites of application of a estradiol therapeutic transdermal system and successively at the sites of application of a gel containing estradiol. Due to the topical intolerance, the therapy was switched to oral estrogen, which caused a systemic pruritic rash. Positive patch tests with estradiol led to the diagnosis of type IV allergic dermatitis due to transdermal estradiol and to a gel containing estradiol. Systemic contact dermatitis due to oral estradiol was also diagnosed. CONCLUSION: Even though allergic contact dermatitis from estradiol is extremely rare, local side effects from estradiol systems must be kept in mind and correctly diagnosed. Patch tests allow identification of the causative agent. In the case of primary sensitization to topical estradiol, oral estrogens must be prescribed cautiously to avoid systemic reactions.

Administration, Cutaneous↗
PubMed2005

[Diagnostic difficulties in differentiation between atopic dermatitis and seborrheic dermatitis in infants].

On the basis of two children with coexistence of atopic and seborrhoeic dermatitis, authors emphasize similarity of clinical symptoms and chronic, recurrent course of these diseases. Atopic dermatitis and seborrheic dermatitis are most common reasons of skin disorders in infants. Location and character of atopic lesions are atypical during infancy. Most often they occur on face and have erythematous-exfoliative and papulovesicular character. Pruritus and anxiety, especially in younger children are often seen. On the contrary seborrhoeic lesions are mostly seen in typical spots, including hairy head skin, where they form characteristic yellow seborrhoeic scales. Usually pruritus is not seen. Authors pay attention to heterogeneous etiopathogenesis of these diseases and underline the importance of early differentiation, which allows application of proper therapy.

Dermatitis, Atopic↗
PubMed2001

[Shiitake dermatitis: flagellate dermatitis after eating mushrooms].

The name of flagellate dermatitis originates from self-flagellating medieval people. This dermatitis is not rare as a drug eruption following bleomycin therapy. An identical skin eruption caused by the mushroom shiitake Lentinus edodes is more common but reported mostly from Japan. We saw a 67-year-old patient who presented with the typical linear scratch marks after a dinner in a Chinese restaurant. The basic mechanism is a toxic epidermal damage. Since it is not clear why the dermatitis does not occur frequently since Shiitake is the second most popular mushroom in the world, we discuss possible cofactors that may trigger the toxic reaction.

Administration, Oral↗
PubMed2001

The ACVD task force on canine atopic dermatitis (III): the role of antibodies in canine atopic dermatitis.

Although an important pathogenic role for IgE is established in the case of allergic asthma and rhinitis in man, its role in atopic dermatitis is less clear. There are many studies where allergists and immunologists have provided evidence in favour of such a role, whereas dermatologists are less than convinced. In dogs, however, there is an abundance of clinical evidence implying that atopic dermatitis is antigen driven, and recent studies suggest that there may be a role for IgE, not only in the effector pathway, but also in antigen capture. Although an IgG response often accompanies an IgE response in dogs with atopic dermatitis, there is little evidence in support of a pathogenic role in respect of the former isotype.

Allergens↗