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Results for “Cytochemical Effects”

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At least 91 records · Page 5Linked to original sources
PubMed1979

[Increased ATP-hydrolase activity of the brain mitochondria under the effect of aminazine (electron cytochemical study)].

The localization of Mg-stimulated ATPase activity was determined in the sensomotor cortex mitochondria of Wag rats after aminazin administration (15 mg/kg). Apart from normal mitochondria containing no reaction product, a number of altered mitochondria with different localization in them of the ATPase reaction product were recorded. The intact animals showed no sediment in the mitochondria. It is suggested that aminazin-induced increase in ATP-hydrolase activity is caused by two factors: neuroleptic-induced decrease in glycolytic and oxidative cell activity and increased permeability of mitochondrial membranes.

Adenosine Triphosphatases↗
PubMed1989

[Electron microscopic-cytochemical study of the effect of vinblastine on synaptosome adenylate cyclase in the rat cerebral cortex].

Adenylate cyclase activity was demonstrated by means of electron microscopic cytochemistry in rat cortical synaptosomes incubated under various conditions. It was found that vinblastine caused remarkable changes in the reaction product localization: the limiting membrane reaction diminished, but the number of synaptosomes were seen to contain a course granular precipitate filling up almost the whole presynaptic cytoplasm. The regulatory role the microtubules play in the distribution of adenylate cyclase on cellular membrane is discussed.

Adenylyl Cyclases↗