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Lanthony 15-Hue Desaturated Test for screening of early color vision defects in uncomplicated juvenile diabetes.

PURPOSE: To identify the most appropriate test for screening of early color vision abnormalities in uncomplicated juvenile diabetes. METHODS: Enrolled in this study were 39 diabetic adolescents, characterized by optimal Early Treatment Diabetic Retinopathy Study criteria for visual acuity, transparent dioptric means and angiographically normal retinas. Color vision was examined with Standard Pseudoisochromatic Plates (Part 2, SPP2), Roth 28-Hue Test (R28), Farnsworth-Munsell 100-Hue Tests (FM100), and Lanthony 15-Hue Desaturated Test (L15). Color confusion score (CCS) and desaturation angle (DSAT) were measured on L15 only. Thirty-nine normal subjects served as a control group. Poor metabolic control was an exclusion criteria. RESULTS: CCS was significantly higher in the patients than in the controls (37.8 +/- 11.1 vs 0 +/- P < .001) and normal scores were found in only 4 diabetic patients. DSAT values were spread, not showing a well-defined axis of the defect. The results of FM100 were clinically reliable but affected by a longer execution time. R28 and SPP2 demonstrated a low sensitivity, as all patients scored normally with both tests. CONCLUSIONS: Impaired color vision is a common observation even in patients with uncomplicated juvenile diabetes. Our results indicate that L15 is the most suitable test for screening of early color vision abnormalities in these subjects.

Adolescent↗

AcrySof Natural SN60AT versus AcrySof SA60AT intraocular lens in patients with color vision defects.

PURPOSE: To determine whether implantation of the AcrySof Natural intraocular lens (IOL) worsened the severity of existing color deficit in congenital partial red-green color deficient individuals (CPRG). METHODS: A prospective controlled randomized double-masked analysis of 30 consecutive patients with CPRG defect and bilateral cataracts received a Natural IOL (test group) in 1 eye and a single-piece AcrySof IOL (control group) in the other eye. Patients were tested unilaterally to detect CPRG defect using Ishihara pseudoisochromatic plates and the Farnsworth D-15 test. Plates 1 to 21 measured the Ishihara error score; plates 22 to 25 indicated severity of defect based on clarity of both numerals as partial mild/moderate (both visible), partial severe defect (only 1 visible). The D-15 test is based on number of diametrical crossings on the circular diagram; severity is graded as mild (1 crossing), moderate (2 crossings), or severe (>2 crossings). Tests were performed before and after IOL implantation at 1, 3, and 6 months. At mean follow-up of 6.13 months +/- 1.2 (SD), analysis of variance test judged the difference in error scores and cross tabulation represented change in number of diametrical crossings. RESULTS: The mean age was 62.3 +/- 8.5 years. All patients were men. Before IOL implantation, all patients had moderate CPRG defect on both tests. The Ishihara error score in the test and control groups did not reveal statistically significant differences (P = .505 and P = .119, respectively). With D-15, none of the patients in the test or control group showed >2 crossings. CONCLUSION: The implantation of AcrySof Natural IOL did not worsen the preexisting severity of color defect in CPRG individuals.

Acrylic Resins↗

A maximum motion technique for assessment of color vision defects.

Several luminance-matching methods, such as flicker fusion and the minimum motion technique (MMT), are capable of detecting certain forms of abnormal color vision. We present evidence that the heterochromatic fusion nystagmus (HFN) luminance matching technique can discriminate among normal trichromats, protanopes, and deuteranomals. The HFN luminance matching technique has the advantage that it provides a positive indication of isoluminance (maximization of motion) as opposed to the MMT and flicker fusion methods, which indicate isoluminance by the minimization of motion and flicker, respectively. We tested 16 normal trichromats, 6 protanopes, and 4 deuteranomals with the HFN technique. Results indicate that HFN is a useful tool for examining color vision. Because the HFN stimulus elicits reflexive eye movements (optokinetic nystagmus) that follow the apparent motion of the stimulus, HFN luminance matching will be particularly useful in animal and infant research, where other color vision tests are difficult to implement.

Adolescent↗