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At least 91 records · Page 5Linked to original sources
PubMed1987

Chyle: a masquerading etiology of pericardial effusion.

A 25-year-old man with massive pericardial effusion is presented. The high lymphocyte amount and cytological analysis of the aspirated fluid suggested tuberculous or malignant pericarditis. The chylous nature of the effusion was only recognized after hemipericardiectomy, when reaccumulation of fluid into the pleural space appeared. This was successfully managed by medium chain triglyceride diet.

Adult↗
PubMed1996

Severe cervical chyle fistula after radical neck dissection.

The case of a chylous cervical fistula detected immediately after radical neck dissection is presented. The flow and metabolic derangements secondary to depletion of fluid, electrolytes, and protein required the ligation of the thoracic duct at the thoracic cavity. The various possible treatments of chylous fistula are reviewed.

Blood Proteins↗
PubMed1996

Bile but not chyle lipoprotein is an important source of arachidonic acid for the rat small intestine.

Arachidonic acid (AA) functions as a structural component, eicosanoid precursor and surface material for chylomicron production in the gastrointestinal tract. The origin of this AA is poorly characterized. [3H]AA labelled chylomicrons and [14C]AA albumin-FFA were injected intravenously into biliary diverted rats and controls. Radioactivity in tissue lipids was measured after different time intervals. Output of 3H and 14C in bile was 8% of the injected dose during 24 h. Radioactivity of the upper small intestine but not of colon and stomach increased with time. Bile drain reduced the recovered amounts of radioactivity in upper small intestine by 75% after 24 h. In stomach and colon 3H/g tissue was 16-20 fold lower than in liver after 24 h. Recovery of 3H in liver was higher than of 14C. In liver 3H/g tissue was 15-40 fold higher than in stomach and colon after 10-60 min. Equilibration between AA pools of liver and other organs was not complete after 96 h. Biliary phospholipid is an important source of AA for the small intestine.

Albumins↗
PubMed1998

Output of chyle as an indicator of treatment for chylothorax complicating oesophagectomy.

BACKGROUND: The management of chylothorax complicating oesophagectomy remains controversial. Even if medical management alone can be successful, some authors advocate early reoperation. The aim of this retrospective study was to identify the clinical variables associated with a high probability of full recovery with medical treatment. METHODS: Among 850 Lewis procedures performed for oesophageal carcinoma, 23 patients (2.7 per cent) developed postoperative chylothorax despite systematic preventive ligation of the main thoracic duct. Patients who responded to conservative management were compared with those requiring reoperation for preoperative radiotherapy, unilateral versus bilateral pleural effusion, delay of occurrence of the chylothorax, and ratio of mean chylous output to body-weight 1 and 5 days after its onset. RESULTS: Conservative management was successful in 14 patients with a mean(s.d.) delay of 12(5) (range 7-21) days and there were no hospital deaths. Reoperation was necessary in nine patients; there were two postoperative deaths and no recurrence of the chylothorax. The only significant difference between reoperated and medically treated patients was the mean(s.d.) chylous output at day 5: 23.5(16.6) versus 6.7(5.5) ml per kg body-weight (P< 0.001). At this time, the output was less than 10 ml/kg in 12 of 14 patients in whom medical treatment was successful (sensitivity 86 per cent), and equal to or greater than this cut-off value in all the patients who underwent reoperation (specificity 100 per cent). CONCLUSION: The ratio of chylous output to body-weight on the fifth day after the onset of a chylothorax complicating oesophagectomy seems to reliably predict the success of continuing medical treatment.

Adult↗