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PubMedDate not supplied

Assay of calcium borogluconate veterinary medicines for calcium gluconate, boric acid, phosphorus, and magnesium by using inductively coupled plasma emission spectrometry.

An inductively coupled plasma spectrometric method is described for the determination of 4 elements (Ca, B, P, and Mg) in calcium borogluconate veterinary medicines. Samples are diluted, acidified, and sprayed directly into the plasma. Reproducibility relative confidence intervals for a single sample assay are +/- 1.4% (calcium), +/- 1.8% (boron), +/- 2.6% (phosphorus), and +/- 1.4% (magnesium). The total element concentrations for each of 4 elements compared favorably with concentrations determined by alternative methods. Formulation estimates of levels of calcium gluconate, boric acid, phosphorus, and magnesium salts can be made from the analytical data.

Animals↗
PubMed2003

The effect of prostaglandin E2 and calcium gluconate on orthodontic tooth movement and root resorption in rats.

Possible modifications in orthodontic tooth movement (OTM) and root resorption as a result of local injections of prostaglandin E2 (PGE2) alone and with calcium gluconate (Ca) formed the aim of the present study. Twenty-four 8-week-old male Wistar rats were selected and randomly divided into three groups of eight. Both quadrants of the upper jaws of the first group of animals were used; therefore this group comprised two groups: control and normal. The upper left first molars of these eight animals were not placed under orthodontic force and received no injection, to serve as the normal group, considered for root resorption comparison only. The control group had localized submucosal injections of normal saline on the buccal side of the upper right first molar. In the third group, 0.1 ml of 1 mg/ml PGE2 was injected at the same site and the fourth group received an intraperitoneal injection of 200 mg/kg Ca (10%) in addition to the PGE2. All the injections were performed on days 0 and 7. The orthodontic appliance consisted of a closed coil spring ligated to the upper right first molar and incisor, exerting a force of 60 g during the 21-day experimental period, after which the animals were sacrificed. Palatal halves were removed for histological examination and for calculation of the amount of root resorption. Statistical analysis of data showed a significant (P < 0.05) acceleration in OTM after PGE2 injection compared with the control group. The addition of Ca reduced OTM but a significant increase (P< 0.05) was still recorded. A significant difference (P < 0.05) in root resorption was only observed between the PGE2 and normal groups. The findings show the importance of calcium ions working in association with PGE2 in stabilizing root resorption while significantly increasing OTM.

Analysis of Variance↗
PubMed1977

Effects of oral calcium gluconate on gastric acid secretion and serum gastrin concentration in man.

A single oral dose of 4-46 mmol calcium gluconate at pH 5-6 was administered intragastrically to 15 male volunteers without gastrointestinal disease. There was a significant rise in acid output from 30-90 minutes after the calcium was given compared with the basal hourly collection. The serum gastrin level 30 minutes after calcium administration was significantly raised, but no correlation could be demonstrated between the acid and gastrin responses. Serum calcium levels were unchanged throughout. An equimolar dose of magnesium sulphate had no such effects. This study suggests that the intragastric administration of calcium results in independent release of gastric acid and gastrin from the gastric mucosa.

Administration, Oral↗
PubMedDate not supplied

Effect of 24 hour room temperature hold time on the heat resistance of Bacillus coagulans spores suspended in 10% Calcium Gluconate, USP.

In an industrial application, biological indicator test units can often remain at room temperature for several hours prior to a steam sterilization validation cycle. A study was performed using the biological indicator Bacillus coagulans suspended in 10% Calcium Gluconate, USP, to determine if room temperature hold time had an effect on the resistance of the biological indicator. The results indicated that no significant change in resistance was seen for hold times up to 24 hours at room temperature.

Bacillus↗
PubMed1990

[Treatment of patients with postmenopausal and steroid-induced osteoporosis using sodium fluoride combined with vitamin D2 and calcium gluconate].

9 patients with postmenopausal and 5 patients with steroid-induced osteoporosis, mean age 57.9 +/- 7.76 years, were treated in the course of one year with sodium fluoride (Fluosen) in a dose of 45 mg/24 h in combination with calcium gluconate (2 g/24 h) and oil solution of vit D2 (2 mg/week). In the course of the treatment a considerable easing of the pains in the most affected parts of the skeleton was found and the height remained at the same level before and after the treatment. This correlates with the statistically significant increase of the serum levels of the total alkaline phosphatase and its bone isoenzyme by keeping a normal kalium phosphorous balance as well as with the x-ray data for retaining the bone changes liked with the osteoporosis.

Adrenal Cortex Hormones↗
PubMed1979

[Sequential renal scintiscanning with 99mTc calcium gluconate. Possibilities and limitations].

The methods used in the study of the kidney are discussed and sequential scintiscanning is suggested as a means of supplementing purely morphological data with morpho-functional data. An account of the modalities employed with a variety of radio-compounds and reasons are proffered for the choice of 99mTc calcium gluconate. Results obtained with this method are described. These include the acquisition of information concerning the function and shape of the renal parenchyma and urinary tracts. Organic classification of the results will be dealt with in a later paper. It is felt that the method proposed is a valuable diagnostic aid with interesting possibilities in the study of diseases of the urinary apparatus.

Calcium Gluconate↗
PubMed1993

The role of calcium gluconate in the treatment of hydrofluoric acid eye burn.

Hydrofluoric acid is used for different purposes in industry and in the home as a rust remover. Most exposures are accidental and may result in severe superficial and deep tissue injury as well as systemic toxicity. There is uncertainty regarding the optimal treatment of hydrofluoric acid eye injury. A patient in whom a solution of 49% hydrofluoric acid induced a large corneal erosion is described. Repeated instillation of 1% calcium gluconate eye drops combined with the conventional treatment of acid eye burns resulted in a complete and quick recovery.

Adult↗
PubMed1989

The influence of PTH, calcium gluconate and EDTA on the parotid saliva in the goat.

1. The role of exogenous parathyroid hormone (PTH) and stimulation or inhibition of endogenous hormone release, on the parotid gland of normal and thyroparathyroidectomized (t.x.p.t.x.) goats was studied. 2. The intravenous infusion of PTH and EDTA produced a transitory rise in saliva flow rate in intact animals. In t.x.p.t.x. goats the flow of saliva decreased transiently throughout the infusion. 3. The calcium levels in parotid saliva was unchanged throughout the infusion of PTH, EDTA, calcium gluconate both alone or with propranolol, in either intact or t.x.p.t.x. animals. 4. The parathyroid hormone infusion caused an increase in salivary phosphate concentration in both intact and operated goats. The effects of PTH upon the salivary flow and concentration of P are discussed.

Analysis of Variance↗