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Preliminary studies on the acid soluble glycoproteins in serum and their diagnostic value for acute inflammatory diseases in cattle.

The concentration of acid soluble glycoproteins (ASG) in serum was determined by the Coomassie brilliant blue G-250 method as a means of assessing the amount of the acute phase protein in bovine serum. The mean (+/- SD) ASG concentration in sera from 30 normal dairy cows was 98.0 (+/- 31.5) mg/dl (range 42.2-161.0 mg/dl). The mean serum ASG concentrations in cattle suffering from enzootic bovine leukosis and enzootic bovine leukosis associated with glomerulonephritis were significantly (p less than 0.001) higher than those of normal cows. Elevated ASG concentrations were observed in cows with acute clinical mastitis. Higher (1.1-2.9 fold) ASG concentrations were observed in sera from cattle on the fifth day after surgery than in those taken at the preoperative stage. The measurement of ASG in serum could be used routinely in bovine clinical medicine as a useful indicator of inflammatory processes.

Acetylglucosaminidase↗

Epidemiology of tick-borne diseases of cattle in Zimbabwe. I. Babesiosis.

A survey on the incidence of antibodies to Babesia bigemina and Babesia bovis in one to three year old calves at 274 localities in Zimbabwe revealed that B. bigemina occurred throughout the country together with its main vector, Boophilus decoloratus. The distribution of B. bovis followed closely that of its vector Boophilus microplus which is limited to the eastern part of the country. Enzootic stability for B. bigemina was recorded in most of the communal tribal areas where regular dipping of cattle had been interrupted for several years but was less common on commercial farms where regular dipping is practised. Enzootic stability for B. bovis was restricted to a few localities in communal areas and the parasite was rare on commercial farms.

Animals↗

Tick-borne diseases of cattle in Paraguay. II. Immunisation against anaplasmosis and babesiosis.

A total of 102 susceptible adult Holstein Friesian cattle imported into an area of Paraguay where anaplasmosis and babesiosis are endemic were immunised by infection with Anaplasma centrale and attenuated forms of Babesia bigemina and Babesia bovis obtained from Uruguay. The results indicated that the attenuated forms of both Babesia species protected cattle against heterologous field challenge whereas A. centrale did not invariably confer sufficient protection against a field challenge of A. marginale.

Anaplasma↗

Epidemiology of tick-borne diseases of cattle in Zimbabwe. II. Anaplasmosis.

A survey on the incidence of antibodies to Anaplasma marginale in one- to three-year-old cattle was carried out in Zimbabwe using the capillary tube agglutination test. Antibodies were detected in all but one of 118 batches of sera collected from different localities throughout the country. There was no clear relationship between the frequency of occurrence of positive serological reactors, which was similar in both commercial and communal farming areas, and the incidence of clinical anaplasmosis. However, the highest numbers of cattle exhibiting positive reactions were generally recorded from the areas that were most heavily tick infested. There was evidence that wild ungulates may serve as reservoirs of infection as antibodies to A. marginale were detected in sera from buffalo (Syncerus caffer) and impala (Aepyceros melampus).

Anaplasma↗

Tick-borne diseases of cattle in Paraguay. I. Seroepidemiological studies on anaplasmosis and babesiosis.

A serological survey was carried out in Paraguay to determine the prevalence of antibodies to Anaplasma marginale, Babesia bigemina and Babesia bovis. The results suggest that the parasites are widely distributed throughout the country with prevalence rates of 92% for A. marginale, 79% for B. bigemina and 71% for B. bovis. Epidemiological studies on calves demonstrated that initial infection with the three blood parasites occurs in most animals within the first nine months of life. It is likely therefore that most of the country can be considered as being enzootically stable with respect to anaplasmosis and babesiosis.

Anaplasma↗

Targeting ticks for control of selected hemoparasitic diseases of cattle.

Development in and transmission of hemoparasites by tick vectors are phenomena closely synchronized with the tick feeding cycle. In all known life cycles, initial infection of tick tissues occurs in midgut epithelial cells and transmission is effected as ticks feed after parasites have developed and multiplied in salivary glands. Many factors reviewed affect development and transmission of hemoparasites by ticks including age of ticks, artificial temperature, climate and/or season, tick stage or sex, hemoparasite variation, concurrent infection of ticks with other pathogens, host cell susceptibility, transovarial transmission, effect of hemoparasites on tick biology, and the effect of infecting parasitemia level in cattle on infection rates in ticks. Four hemoparasites of cattle, Anaplasma marginale, Cowdria ruminantium, Theileria parva, and Babesia spp., are all dependent on ticks for biological transmission. Babesia is transmitted transovarially whereas the other three are transmitted transstadially. Mechanical transfer of infective blood via fomites and mouthparts of biting arthropods is also a major means of transmission for Anaplasma marginale but not of the others. Potential control methods for hemoparasites that target parasites as they are developing in their respective tick hosts include tick control, vaccines (against ticks and parasites), and drugs (against ticks and parasites). Successful application of control strategies will be dependent upon thorough understanding of parasite developmental cycles, biology of the tick vectors and the immune response of cattle to ticks and to hemoparasites. The most effective control measures will be those that are targeted against both ticks and the hemoparasites they vector.

Animals↗