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Evaluation of meniscal repair with serial magnetic resonance imaging: a comparative study between conventional MRI and indirect MR arthrography.

OBJECTIVE: To prospectively investigate the healing process of meniscal repair with plain magnetic resonance imaging (MRI) and indirect MR arthrography and to compare the two methods. MATERIALS AND METHODS: Twenty patients with an arthroscopic meniscal repair without clinical symptoms underwent conventional and indirect MR arthrography of the affected knee, 3, 6 and 12 months after the index operation applying a T1-w Spin Echo sequence in three planes. The size of the tear gap was measured on transverse images. The signal-to-noise ratio and the configuration of the abnormal signal were evaluated in the coronal images. RESULTS: All patients demonstrated abnormal signal intensity at the side of the meniscal repair. The size of the gap at the previous tear side, reduced significantly by 45 and 40% on conventional MRI and indirect MR arthrography respectively, from 3 months to 1 year (P < 0.05). The signal-to-noise ratio of the intrameniscal abnormal signal reduced significantly and approximately 50% from 3 to 6 months, and from 6 to 12 months postoperatively, as demonstrated with indirect MR arthrography. However, as opposed to normal meniscus, the signal-to-noise ratio of the abnormal area remains 5.5 times higher 12 months postoperatively. In contrast, the reduction of signal-to-noise ratio of the abnormal area at conventional MRI was not significant even from 3 to 12 months. In 90% of the cases, the indirect MR arthrography showed the intrameniscal abnormal signal on plain MRI, to extend to the articular surface as opposed to 25% on plain MRI. CONCLUSION: With indirect MR arthrography, the natural process of meniscal healing can be evaluated. Significant reduction of the size of the tear gap and significant reduction of the signal-to-noise ratio of the abnormal signal as well as its configuration are the main parameters interpretating the normal healing process.

Adolescent↗

Disorders of acetabular labrum and articular cartilage in hip dysplasia: evaluation using isotropic high-resolutional CT arthrography with sequential radial reformation.

OBJECTIVE: Acetabular labral tear may predispose to adjacent articular cartilage disorder and hip osteoarthritis in patients with hip dysplasia. We evaluated the diagnostic ability of isotropic computed tomography (CT) arthrography with radial reformation technique for detection of acetabular labral and articular cartilage disorders, and evaluate those interactions in hip dysplasia. METHODS: Forty-one hips in 29 patients with hip dysplasia received CT arthrography with isotropic spatial resolution of 0.5mm. After processing of multiplanar radial reformation over the whole acetabular circumference, frequencies of labral tear and acetabular cartilage disorder were evaluated at six divided zones of the weight-bearing areas. Of the 41 hips, 20 hips underwent arthroscopic examinations, and sensitivity, specificity and accuracy for detecting labral tear and acetabular cartilage disorder by CT arthrography were calculated using the arthroscopic findings as the standard of reference. RESULTS: The sensitivity, specificity and accuracy of CT arthrography were 97%/87%/92% for labral tear and 88%/82%/85% for acetabular cartilage disorder, respectively, using arthroscopic findings as the reference. The CT arthrography showed significantly higher frequency of labral and acetabular cartilage disorders at the anterior zones. Those zones with labral tear had significantly higher frequency of adjacent cartilage disorder than zones without labral tear. CONCLUSIONS: Isotropic CT arthrography with radial reformation technique allowed simultaneous, accurate assessment of labral and cartilage disorders in the whole acetabular circumference. Our findings indicated that labral tear is closely associated with adjacent cartilage disorder in hip dysplasia.

Acetabulum↗

Magnetic resonance imaging or arthrography for shoulder problems: a randomised study.

OBJECTIVE: Diagnostic technologies are often assessed merely by their accuracy, rather than by their impact on diagnosis and patient management. To this end the authors have undertaken a study to assess the diagnostic and therapeutic impact of magnetic resonance imaging (MRI) and arthrography of the shoulder for patients referred from a rheumatology clinic. METHODS AND PATIENTS: Patients referred from a rheumatology clinic with symptoms warranting imaging of the shoulder were randomised to either MRI or arthrography. Data on the clinician's diagnostic confidence and management were recorded before and after imaging using questionnaires. Patients were followed-up at least 10 months after imaging to see how management plans evolved, and what proportion of patients required further imaging. RESULTS: Fifty three shoulders underwent imaging over a year and entered into the study; 29 randomised to MRI and 24 to arthrography. Both MRI and arthrography had a similar beneficial diagnostic impact in terms of clinical diagnoses (refuted and retained) and new diagnoses established. MRI and arthrography had a similar therapeutic impact, although MRI was associated with a significant shift towards surgical intervention. CONCLUSION: MRI and arthrography a have similar diagnostic and therapeutic impact.

Adult↗

Evaluation of rotator cuff tears with magnetic resonance arthrography.

The size and morphologic features of rotator cuff tears may influence treatment selection and affect final outcomes. Magnetic resonance arthrography allows observation of these features and other intraarticular structures. To assess the utility of magnetic resonance imaging in assessing size and morphologic features, we retrospectively reviewed observations on 41 shoulders in 37 consecutive surgically treated patients (mean age, 63.2 years) who had magnetic resonance imaging followed by magnetic resonance arthrography. The maximum rotator cuff defect size in the anteroposterior direction defined transverse size, and the maximum rotator cuff defect size in the mediolateral direction defined longitudinal size. Sensitivities for detecting full-thickness rotator cuff tears by magnetic resonance imaging and magnetic resonance arthrography were 90.2% and 100%, respectively. Maximum longitudinal and transverse dimensions of the tear as shown by magnetic resonance arthrography correlated better with intraoperative measurements (r2 = 0.85 transversely, 0.92 longitudinally) than magnetic resonance imaging measurements (r2 = 0.47 transversely, 0.26 longitudinally). The reproducibility of the two methods is similar. Magnetic resonance arthrography also allowed morphologic classification of the torn tendon as blunt end, tapering end, indistinct end, horizontal tear, and global tear. There was good agreement in classifying torn edges; the imaging findings agreed with findings at surgery. Magnetic resonance arthrography was more accurate in evaluating rotator cuff tear size and morphologic features than conventional magnetic resonance imaging.

Adult↗

Assessment of knee cartilage in cadavers with dual-detector spiral CT arthrography and MR imaging.

PURPOSE: To assess dual-detector spiral CT arthrography in the evaluation of the entire knee cartilage obtained from cadavers. MATERIALS AND METHODS: Two independent observers characterized articular cartilage in 12 cadaver knees in which MR imaging and dual-detector spiral CT arthrography were performed and compared their findings to those found during macroscopic assessment. The sensitivity and specificity of MR imaging and spiral CT arthrography for detecting grade 2A or higher and grade 2B or higher cartilage lesions, the Spearman correlation coefficient between arthrographic and macroscopic grading, and kappa statistics for assessing interobserver reproducibility were determined. RESULTS: At spiral CT arthrography, sensitivities and specificities ranged between 80% and 88% for the detection of grade 2A or higher cartilage lesions and ranged between 85% and 94% for the detection of grade 2B or higher cartilage lesions. At MR imaging, sensitivities and specificities ranged between 78% and 86% and between 76% and 91% for the detection of grade 2A or higher and grade 2B or higher cartilage lesions, respectively. Spearman correlation coefficients between spiral CT arthrography or MR imaging and macroscopic grading of articular surfaces were 0.797 and 0.702, respectively. CONCLUSION: Dual-detector spiral CT arthrography of the knee is a valuable method for the assessment of open cartilage lesions of the entire knee.

Aged↗

Evaluation of the acetabular labrum at 3.0-T MR imaging compared with 1.5-T MR arthrography: preliminary experience.

Institutional review board approval and informed consent were obtained for this HIPAA-compliant study. The purpose of this study was to prospectively compare imaging of the acetabular labrum with 3.0-T magnetic resonance (MR) imaging and 1.5-T MR arthrography. Eight patients (four male, four female; mean age, 38 years) with hip pain suspicious for labral disease were examined at both MR arthrography and MR imaging. Presence of labral lesions, paralabral cysts, articular cartilage lesions, subchondral cysts, osteophytes, and synovial herniation pits was recorded. There was arthroscopic correlation of findings in five patients. MR imaging depicted four surgically confirmed labral tears that were identified at MR arthrography, as well as one that was not visualized at MR arthrography. MR imaging helped identify all other pathologic conditions that were diagnosed at MR arthrography and helped identify one additional surgically confirmed focal articular cartilage lesion. These results provide encouraging support for evaluation with 3.0-T MR imaging over 1.5-T MR arthrography.

Acetabulum↗

Synovial plicae and chondromalacia patellae: correlation of results of CT arthrography with results of arthroscopy.

The purpose of this study was to compare computed tomographic (CT) arthrography with arthroscopy in the evaluation of patients with anterior knee pain. The authors studied 23 patients with patellar plicae at CT arthrography. Twenty of 21 patients presumed to have medial plicae at arthroscopy had similar findings at CT arthrography (sensitivity, 95%; specificity, 100%). However, 10 of 12 suprapatellar plicae and 11 of 11 lateral plicae seen at CT arthrography were not seen at arthroscopy. All 11 patients with a diagnosis of no or mild chondromalacia patellae at arthroscopy had similar CT arthrographic findings, whereas seven of 11 patients presumed to have moderate or severe chondromalacia patellae at arthroscopy had matching CT arthrographic results (sensitivity, 100%; specificity, 73%). CT arthrography was much more accurate in classifying plicae as thick (66%) as opposed to classifying plicae as thin (17%). The authors conclude that CT arthrography is an accurate and specific modality for distinguishing patients with anterior knee pain due to plicae from those with anterior knee pain due to differing causes.

Adult↗

Is MR better than arthrography for evaluating the ligaments of the wrist? In vitro study.

The purpose of this study was to determine the relative merits of MR imaging and three-compartment digital arthrography in the assessment of carpal ligaments in vitro. We performed MR imaging and arthrography in 10 normal wrists of fresh cadavers ranging in age from 48 to 71 years, and compared the appearance of the interosseous ligaments and triangular fibrocartilage complex with findings on anatomic sections of the joints. In six of the specimens, relatively T1-weighted MR images, 800/20 (TR/TE), preceded three-compartment digital arthrography performed with standard contrast material. In the other four specimens, arthrography, using an MR solution of iodinated contrast material mixed with cupric sulfate and gelatin, was performed before MR imaging. This was done to mimic the intraarticular fluid that might be seen in an injured wrist. MR allowed accurate assessment of the triangular fibrocartilage complex and scapholunate ligament in eight of 10 cases. Consistent MR visualization of the lunotriquetral ligament was difficult. Three-compartment digital arthrography allowed accurate assessment of the triangular fibrocartilage complex and scapholunate and lunotriquetral ligaments in all 10 cases. We concluded that MR is useful but inferior to arthrography in the evaluation of interosseous ligaments and the triangular fibrocartilage complex.

Aged↗

Evaluation of chronic wrist pain. Arthroscopy superior to arthrography: comparison in 39 patients.

39 patients with chronic wrist pain underwent arthrography and arthroscopy to reveal disruptions of the triangular fibrocartilage complex (TFCC) and/or interosseous ligaments. TFCC disruption was diagnosed arthroscopically in 15 cases of which arthrography revealed the disruption in only 7. In 3 other patients, arthrography showed rupture of the TFCC: however, arthroscopy showed no defects. Rupture of an interosseous ligament was diagnosed arthroscopically in 6 patients in all of whom it was also revealed by arthrography. In 6 other patients, arthrography showed disruption of an interosseous ligament not verified by arthroscopy. We conclude that arthroscopy is superior to arthrography for diagnosing chronic wrist pain.

Adolescent↗

Magnetic resonance knee arthrography. Enhanced contrast by gadolinium complex in the rabbit and in humans.

This study contains the fundamentals and the technique of the intraarticular application of an MRI contrast agent in connection with magnetic resonance imaging (MRI arthrography). It also presents the resulting clinical relevance for knee joint diagnostics. The significance of MRI arthrography is linked above all to the central question of whether or not it is possible to depict the hyaline cartilage, its surface and its thickness with the help of MRI arthrography. MRI arthrography was used for in vitro examinations of rabbit knee joint cartilage and human joint cartilage. The in vivo application was carried out in 73 patients. Apart from the metric evaluation and the assessment of the information content of the MRI image, the corresponding histologic sections were made in 20 knee joints in order to compare the cartilage surface and the thickness of the cartilage with the results in the MRI image. The optimum amount of contrast agent for visualization was determined, the uptake and clearance of the contrast agent from the cartilage were assessed, and trace elements from the cartilage were also analyzed. The examination showed that the molecular structure of the contrast agent (gadolinium-DTPA) does not prevent the uptake of the contrast agent into the matrix of the hyaline cartilage. But this process is reversible. Thus, 14 hours after the intraarticular application of the contrast agent no measurable traces of gadolinium-DTPA could be established. The intraarticular application of the contrast agent also made it possible to achieve a constant and reproducible visualization of all joint structures. This affected mainly the surface of the hyaline cartilage. The best imaging quality was achieved with intraarticular application of 30 to 40 mL of a 2 mmolar solution of gadolinium-DTPA. The technique used for the intraarticular application is the same as for the common procedures of knee joint aspiration. The clinical importance of MRI arthrography lies in the fact that a very detailed assessment can be made for therapy planning and furthermore in the possibility to provide the surgeon with answers to specific questions concerning the therapy. Examples are the extent and location of chondromalacia in a patient and the question whether a cartilage fracture has already occurred in osteochondrosis dissecans or not. The evaluation of cartilage together with the possibility to assess all other structures in the knee joint is a special feature of MRI arthrography. The high sensitivity and specificity of this method makes it superior to the examination without contrast agent and comparable to diagnostic arthroscopy.(ABSTRACT TRUNCATED AT 400 WORDS)

Animals↗

[Results of conservative treatment of congenital dislocation of the hip--significance of arthrography].

To evaluate the clinical value of hip arthrography, especially two-directional arthrography, the author compared the treatment results of three different groups, Group A: cases treated without arthrography, Group B: cases treated using anteroposterior arthrography and Group C: cases treated using two-directional arthrography. With Lorenz's method, all three groups achieved about 40% success to G-I, II by Severin's classification. G-III, IV was obtained in Group A, B and C at 50.4%, 19.5% and 2.8%, while cases of open reduction at 3.8%, 37.0% and 55.6%, respectively. By selecting the cases that may obtain G-III, IV with Lorenz's method and by applying open reduction to them, in Group C, reduction was obtained in 93.8% of cases treated with Lorenz's method and 91.7% when cases treated with open reduction were included. Using two-directional arthrography, cases which should not be treated conservatively may be identified to apply open reduction to obtain better overall results.

Adolescent↗

Is sonography performed by the rheumatologist as useful as arthrography executed by the radiologist for the assessment of full thickness rotator cuff tears?

OBJECTIVE: Sonography and arthrography are techniques used to detect rotator cuff tears (RCT). The diagnostic value of sonography executed by a rheumatologist versus that of arthrography performed by a radiologist for assessment of RCT was investigated among patients with unilateral chronic shoulder complaints without an underlying inflammatory rheumatic disease. METHODS: Forty-eight patients underwent sonography, arthrography, and surgical inspection, the results of surgical inspection being the gold standard. RESULTS: Sensitivity for assessment of a full thickness RCT was 0.86 for sonography and 0.77 for arthrography, specificity was 0.88 for sonography and 0.92 for arthrography. CONCLUSION: Compared to arthrography performed by the radiologist, sonography executed by the rheumatologist is as useful for assessment of full thickness rotator cuff tears. Sonography performed by the rheumatologist in combination with history taking and the physical examination during a single visit might change the routine daily practice of rheumatologists.

Adult↗

Wrist ligament injuries: value of post-arthrography computed tomography.

OBJECTIVE: To evaluate the use of post-arthrography high-resolution computed tomography in wrist ligament injuries. DESIGN AND PATIENTS: Thirty-six consecutive patients who had a history and clinical findings suggestive of ligamentous injuries of the wrist were prospectively studied. The findings of three-compartment arthrography and post-arthrography computed tomography (arthro-CT) were compared with those of arthroscopy. The evaluation concentrates on the detection and precise localization of ligament lesions in the triangular fibrocartilage (TFC), the scapholunate ligament (SLL) and the lunotriquetral ligament (LTL). RESULTS: For TFC, SLL and LTL lesions, standard arthrography responded with a sensitivity and specificity of 85% and 100%, 85% and 100%, 80% and 100% respectively, while arthro-CT showed a sensitivity and specificity of 85% and 100%, 100% and 100%, 80% and 100% respectively. The precise localization of the lesions was possible only with arthro-CT. CONCLUSION: The sensitivity and specificity of standard arthrography and arthro-CT are similar, although the latter shows the site of tears or perforation with greater precision, while conventional arthrography demonstrates them indirectly. This precision is essential and may have clinical implications for the success of treatment procedures.

Adolescent↗

Patient perception of magnetic resonance arthrography.

OBJECTIVE: Magnetic resonance (MR) arthrography has been demonstrated to be more accurate than MR imaging alone in the identification of a variety of musculoskeletal pathology. While the complication rate of intra-articular gadolinium: saline injection has been shown to be relatively low, MR arthrography is more invasive, painful, and costly, and less convenient, than MR imaging alone. The purpose of this study was to evaluate patients' perception of the fear and discomfort, and to assess their overall acceptance of the intra-articular gadolinium injection. DESIGN AND PATIENTS: Between October 1997 and January 1998, 113 outpatients who were referred to Yale-New Haven Hospital for MR arthrography of the ankle, elbow, hip, knee, shoulder, or wrist were asked to complete a questionnaire rating their fear of factors most commonly associated with the procedure including "pain", "needles", "complications", and "discovery of results that would lead to surgery". In addition, after having undergone the intra-articular gadolinium:saline injection, patients were asked to rate their perception of pain. RESULTS: While many patients expressed fear of "pain" and "needles", after having undergone the injection their overall pain rating score was low. Only 6% actually found gadolinium arthrography more painful than expected. CONCLUSION: Despite the fact that patients expressed apprehension about certain aspects of MR arthrography, subjects who underwent the intra-articular gadolinium injection considered the discomfort less than expected. Clinicians should not hesitate to order MR arthrography because the accuracy of the procedure is high enough that patients accept the discomfort.

Adolescent↗

Saline versus gadolinium-enhanced magnetic resonance arthrography of porcine cartilage.

RATIONALE AND OBJECTIVES: The authors compared saline and dilute gadopentetate dimeglumine as injectants for magnetic resonance (MR) arthrography. METHODS: Sixty-three lesions were created on the joint surfaces of six pig patellas. MR arthrography (1.5 T) was performed with the specimens in saline and then in 2 mmol gadopentetate dimeglumine by using fat-saturated two-dimensional (2D) and three-dimensional (3D) sequences. Two musculoskeletal radiologists independently interpreted the images. RESULTS: At 2D MR arthrography, reader 1 performed equally well with saline and gadolinium solutes, whereas reader 2 had better sensitivity with the saline solute (P < .05); interobserver agreement was equivalent for saline and gadolinium solutes. With 3D MR arthrography, reader 2 performed equally well with saline and gadolinium solutes, whereas reader 1 had better sensitivity (P < .0001) but poorer specificity (P < .001) with the gadolinium solute; interobserver agreement was significantly better for saline than for gadopentetate dimeglumine (P < .05). CONCLUSION: In this initial evaluation, there was no clear advantage to using gadolinium-enhanced MR arthrography over saline MR arthrography for detecting lesions in porcine hyaline cartilage.

Animals↗

[Indirect MR-arthrography in the follow up of autologous osteochondral transplantation].

PURPOSE: To evaluate the spectrum of findings in indirect MR-arthrography following autologous osteochondral transplantation. PATIENTS AND METHODS: 10 patients with autogenous osteochondral homografts underwent indirect MR-arthrography at three, 6 and 12 months postoperatively. The MR protocol at 1.5 T comprised unenhanced imagings with PD- and T2 -weighted TSE- sequences with and without fat-suppression as well as T1 -weighted fat-suppressed SE-sequences before and after i.v. contrast administration and after active joint exercise. Image analysis was done by two radiologists in conference and comprised the evaluation of signal intensity (Sl) and integrity of the osseous plug and the cartilage surface, as well as the presence of joint effusion or bone marrow edema. RESULTS: At three months, all cases demonstrated a significant bone marrow edema at the recipient and donor site that corresponded to a significant enhancement after i.v. contrast administration. The interface between the transplant and the normal bone showed an increased Sl at three and 6 months in T2 -weighted images as well as in indirect MR-arthrography. The marrow signal normalized in most cases after 6 to 12 months, indicating vitality and healing of the transplanted osteochondral graft. The Sl of the interface decreased in the same period, demonstrating the stability of the homograft at the recipient site. The osteochondral plugs were well-seated in 9/10 cases. Indirect MR-arthrography was superior to unenhanced imaging in the assessment of the cartilage surface. Cartilage coverage was complete in every case. The transplanted hyaline cartilage as well as the original cartilage showed a significant increase of the Sl in indirect MR-arthrography, that did not change in follow up studies. There were no pathological alterations of signal and thickness alterations of the transplanted cartilage in follow up investigations. CONCLUSION: Indirect MR-arthrography is a useful diagnostic tool following autologous osteochondral transplantation. Assessment of transplant vitality, osseous fixation and stability is possible.

Adolescent↗

Rotator cuff interval: evaluation with MR imaging and MR arthrography of the shoulder in 32 cadavers.

PURPOSE: The purpose of this work was to establish the optimal means of evaluation of the rotator cuff interval (RCI) and rotator interval capsule and demonstrate normal anatomy of the RCI using MR imaging and MR arthrography. METHOD: MR arthrography was performed in 32 cadaveric shoulders. In 20 cases, MR imaging was completed prior to arthrography. Pre- and postarthrography studies included standard imaging planes. Images were evaluated by the consensus of two musculoskeletal radiologists with attention to the RCI, rotator interval capsule (measurements on postarthrographic studies), and crossing structures. In five cases, specialized imaging planes were performed after arthrography. RESULTS: The RCI, rotator interval capsule, and crossing structures were best evaluated by MR arthrography. The anteroposterior dimension of the rotator interval capsule could be best depicted on postarthrogram images. CONCLUSION: MR arthrography, with both standard and specialized imaging planes, is a useful way to evaluate the RCI, the rotator interval capsule, and its crossing structures.

Aged↗

Special focus session. MR arthrography.

Direct magnetic resonance (MR) arthrography with injection of saline solution or diluted gadolinium can be useful for evaluating certain pathologic conditions in the joints. It is most helpful for outlining labral-ligamentous abnormalities in the shoulder and distinguishing partial-thickness from full-thickness tears in the rotator cuff, demonstrating labral tears in the hip, showing partial- and full-thickness tears of the collateral ligament of the elbow and delineating bands in the elbow, identifying residual or recurrent tears in the knee following meniscectomy, increasing the certainty of perforations of the ligaments and triangular fibrocartilage in the wrist, correctly identifying ligament tears in the ankle and increasing the sensitivity for ankle impingement syndromes, assessing the stability of osteochondral lesions in the articular surface of joints, and delineating loose bodies in joints. Indirect MR arthrography with intravenous administration of diluted gadolinium may be performed when direct arthrography is inconvenient or not logistically feasible. Although indirect MR arthrography has some disadvantages vis-à-vis direct MR arthrography, it does not require fluoroscopic guidance or joint injection and it is superior to conventional MR imaging in delineating structures when there is minimal joint fluid. In addition, vascularized or inflamed tissue will enhance with this method. Indirect MR arthrography can be used to rule in or diagnose abnormalities and to exclude abnormalities.

Humans↗