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PubMed1988

Irradiation effect of low-energy laser on alveolar bone after tooth extraction. Experimental study in rats.

A histopathological study of the initial healing of extraction wounds following low-energy laser irradiation, using a gallium-arsenide semi-conductor laser, was carried out in rats. The results suggest that this mode of treatment has a beneficial effect on initial bony wound healing. It was found that proliferation of fibroblasts was more prominent in the irradiated group, and so was the formation of trabecular osteoid tissue. The deposition of lead in the newly formed bone suggests a more rapid ossification in the irradiated group.

Alveolar Process↗
PubMedDate not supplied

[Use of thrombin powder after tooth extraction in patients receiving anticoagulant therapy].

Patients with extreme hypocoagulation, which occurs either as an effect of some diseases with coagulation deficiency or because of the anticoagulant therapy (ACT), are a risk group for oral surgery. In the last decades decision to change or interrupt ACT before and after the procedure was abandoned and more often local heamostasis was being achieved by combining chemical and biological substances. The success of the surgical hemostasis and thrombin powder combination was tested on the group of 20 patients with ACT. The results were satisfactory despite thrombin powder solubility in the moist oral environment.

Administration, Topical↗
PubMed1994

[Tooth extraction in hemophiliacs and patients with von Willebrand's disease. Therapeutic proposals apropos of 26 cases].

Extensive bleeding is an important complication of dental extractions in haemophiliacs. Based on 26 case reports, the different therapeutic possibilities are discussed. When general or regional anaesthesia is required, protocols can be proposed for coagulation factor supplementation or even treatment with Minirin. In cases with local anaesthesia, substitution is not required. The importance of mandatory local haemostatic measures combined with antifibrinolytic treatment is emphasized.

Adolescent↗
PubMed1997

[Suppurative abscess-forming mediastinitis after tooth extraction. Consequences for therapeutic approach].

Purulent mediastinitis is a rare but serious complication of a descending odontogenic infection with a high mortality. Diagnosis is difficult and frequently delayed. Physical examination is often nondiagnostic, but may include pronounced edema of the neck and chest. CT scan is the single most important tool for early diagnosis. The treatment is always is surgical, in combination with an extremely high dose of combined antibiotics. Ultimately, we only could save our patient with this therapy.

Abscess↗
PubMed1998

The relationship between chronic cocaine or alcohol use and blood pressure in black men during uncomplicated tooth extraction.

PURPOSE: The object of this study was to determine whether a history of cocaine or alcohol use is associated with blood pressure changes in patients undergoing an uncomplicated mandibular molar extraction. PATIENTS AND METHODS: The blood pressure (BP) values of middle-aged (30 to 40 years of age) black men with different chronic drug histories were compared during extraction procedures. The four different groups were 1) no-drug control, (n = 10); 2) alcohol (n = 15); 3) "crack" cocaine (n = 9); and 4) cocaine (n = 22). RESULTS: The cocaine group's blood pressures were significantly different compared with the blood pressures within the no-drug and alcohol groups (P < .05). The cocaine group's BPs decreased throughout the procedure, and the BPs of the no-drug and alcohol groups rose during administration of the local anesthetic and extraction, and then fell. The BPs of the crack group were highly variable and not significantly different when compared with other groups. CONCLUSION: There is a paradoxical effect of chronic cocaine use on blood pressure that needs to be considered when treating such patients.

Adult↗
PubMedDate not supplied

[The repair process in tooth extraction wounds after implantation of microcrystalline collagen fragments. Histological study in rats].

The author studied histologically, the healing process after dental extraction in rats which sockets were filled with fragments of microcrystalline collagen. Thirty six rats (Rattus Novergicus, albinus, Wistar), young, male, weighting from 90 to 110 g and separated into two groups, control and experimental, of eighteen animal each. All animals were anaesthetized with 10% cloral hidrate, 3 ml/Kg body weight and the right maxillary incisors were extracted. In control animal the sockets were sutured after clot filling, and the experimental sockets were sutured after filling with microcrystalline collagen. Three animals of each group were killed after periods of 1, 3, 6, 14, 21 and 24 days after surgery. The following conclusions were drawn: 1. Microcrystalline collagen caused an evident inflammatory reaction in the inicial phases of the healing process of the sockets. 2. Microcrystalline collagen was biodegraded 6 to 14 days after surgery. 3. Microcrystalline collagen delayed the repair process of the sockets.

Animals↗
PubMed1991

[Histological study of the remains of periodontal membrane at the alveolar wall after tooth extraction].

Histological study of 40 alveolar wounds of altogether 5 dogs have given evidence to the fact that remains of the periodontal membrane could remain in the apical area of the alveoli in their whole width. In the middle part of the alveoli, remains of it are found in a thin layer. In the marginal area, bone can be found lying open with torn remnants, which are lying free in the coagulum. In these adhering rests of the periodontal membrane plenty of dynamic cells as well as dilated vessels can be observed. All these facts lead to the idea of considering the part that the remains of the periodontal membrane may possibly play in the beginning process of alveolar wound healing.

Alveolar Process↗
PubMed1997

A bone regenerative approach to alveolar ridge maintenance following tooth extraction. Report of 10 cases.

TEN PATIENTS WHO REQUIRED two or more anterior teeth extractions were utilized in this study. Extraction procedures were carried out with a full thickness surgical flap approach. After flap reflection, teeth were removed with a minimum of trauma to the surrounding bone. Following extraction silicone-based impression techniques were used to produce a model of the alveolar process and small metal pins were placed in the alveolus to be used as fixed points to make measurements of ridge dimensions. One socket was covered with an expanded polytetrafluoroethylene (ePTFE) barrier membrane (experimental site); the other socket was a conventional control. The soft tissue flaps were then mobilized using periosteal releasing incision and the wound closed with ePTFE mattress sutures. Six months following extraction, patients were treated with flap surgery to expose both extractions sites to remove the ePTFE membranes and to measure ridge dimensions using the pins as fixed points. Clinical and model measurements have shown statistically significant better ridge dimensions at experimental sites than at control (P < or = 0.05). Three patients with exposed membranes had similar dimensional changes as controls. Results from this study suggested that this improved technique offers a predictable alveolar ridge maintenance enhancing the bone quality for dental implant procedures and esthetic restorative dentistry.

Alveolar Bone Loss↗
PubMed1977

[The effect of locally applied Grisaldone or choline salicylate gel on bone healing after tooth extraction in animal experiments].

Comparative histological and experimental animal studies of the effects upon bone wound healing of topically applied choline salicylate gel and Grisaldon showed that Grisaldon tends to hinder the course of reparation of bone, whereas choline salicylate gel has no appreciable influence upon the time course of wound healing. This essential difference is considered to be due predominantly to the exactly opposite behavior shown by the two pharmaceutical preparations in regard to their solubility in water. The difficultly watersoluble Grisaldon tends to exert a longer-drawn-out irritant effect upon the tissue and can be detected in alveoli even after twenty-eight days from administration thereof. By contrast, choline salicylate gel, which is known to be readily soluble in water, will be eliminated already after two days from administration thereof.

Administration, Topical↗
PubMed1994

[Incidence of transient bacteremia following tooth extraction and antibiotic sensitivity of isolated bacteria].

In 12 patients (26%) no bacteria where found in any of the blood culture systems inoculated with blood taken 2-5 minutes after extraction. In the blood from 20 patients however, bot Oxoid and Bio-Merieux (aerobic/anaerobic) cultures proved positive, while in 13 cases only Bio-Merieux and in 2 cases only Oxoid cultures showed bacterial growth. Positive cultures were found only in patients who displayed poor or moderate oral hygiene. The strains most often isolated were Gram-positive; aerobic facultative and obligate anaerobic bacteria were found with similar frequency. Most bacteria proved sensitive to Amoxicillin, while 25% of the isolated bacteria were resistant to Penicillin-G, and 6% of them to cefuroxime and cefaclor.

Adolescent↗
PubMed1994

Interference of the blood clot on granulation tissue formation after tooth extraction. Histomorphological study in rats.

The interference of a blood clot in the first postoperative hours of dental extraction wounds was studied in rats. Sixty male albino rats were divided into two groups: Group I, immediately after extraction of right maxillary incisor the gingival mucosa was approximated and sutured; Group II, after 6 to 8 minutes postoperatively the blood clot was removed with saline irrigation and absorbent paper cones. The mucosa was then approximated and sutured. Six animals in each group were sacrificed after 12 hours, 1, 4, 7 and 10 days. There was a profound delay in healing in Group II since, although a new blood clot was later formed, it was not organized. The quality and the constitution, maintenance and retraction of the clot are the regulating factors in connective tissue formation during alveolar healing.

Alveolar Process↗
PubMed2005

Infective tricuspid valve endocarditis with pulmonary emboli caused by Campylobacter fetus after tooth extraction.

We describe a case of infective endocarditis caused by Campylobacter fetus accompanied by pulmonary emboli. A 52-year-old man was referred to our hospital due to febrile temperatures with a history of dental treatment followed by eating raw meat. Computed tomography revealed multiple infiltrations and a nodule with low attenuation area and feeding vessels. A mobile mass, possible vegetation, attached to the tricuspid valve was detected by transthoracic echocardiography. Two blood cultures disclosed Campylobacter fetus. Long-term antibiotic therapy was given, curing the infection with valvuloplasty. We presented the possibility that infective Campylobacter fetus endocarditis after dental treatment was caused by eating raw meat.

Campylobacter Infections↗
PubMed1982

Myocardial ischemia and tooth extractions: comparison of old myocardial infarction, angina pectoris, and non-specific ischemic heart disease.

The non-specific IHD group showed the highest RPP values, while the angina pectoris group showed the lowest. The result coincided with electrocardiographic findings--non-specific IHD revealed 70% of ECG change, while in angina pectoris, the incidence was 33%. The myocardial infarction group showed intermediate values in both RPP and ECG change. The RPP ratio (RPP at each treatment period/value at pretreatment) was the highest at the anesthetic period for all kinds of IHD. No further severe findings were observed in the myocardial infarction groups, nor in the angina pectoris group, when comparing the clinical parameters, such as anesthetic solution, diazepam, time required for treatment, blood pressure, heart rate, and electrocardiographic observations with those of the non-specific IHD group.

Adult↗
PubMed1994

[Effect of various mouthwashes on wound healing after tooth extraction].

The results of the clinical tests involving 200 patients show that after extraction the use of Meridol, NaF and Chlorhexidine mouthrinses along with careful mouth hygiene helps healing to a great extent. The antiseptic affect of solutions in case of solutions of fluoride content are manifested in an antibacterial way, while solutions of chlorhexidine content act in an antiseptic way. Furthermore the solutions foster good oral hygiene and in this way lessen the number of complications. This is shown by the decreased frequency rate of gingivitis and also the opinions of the patients. Their reports confirm that there is less foetor ox ore, pain and functional insufficiency in mastication. Based on these facts we can state that any of the three mouthrinses considerably helps complication-free healing.

Adult↗
PubMed2006

Effect estimates and methodological quality of randomized controlled trials about prevention of alveolar osteitis following tooth extraction: a systematic review.

OBJECTIVE: To systematically review the scientific evidence derived from randomized controlled trials (RCT) about prevention of alveolar osteitis (AO). STUDY DESIGN: Literature searches were conducted to locate RCTs about prevention of AO. The RCTs were scrutinized for methodological details and categorized according to the preventive intervention studied. Data were analyzed in relation to the frequency of AO. Absolute risk reductions (ARR), and numbers needed to treat were calculated with 95% confidence limits. RESULTS: There was a wide variation in the design and quality of the RCTs (N = 32). The greatest risk reduction for AO was seen for local treatment with tetracycline (ARR, 12%-31%). For a majority of the preventive interventions, the evidence was absent or inconclusive. CONCLUSIONS: Local treatment with tetracycline, and also 0.12% chlorhexidine rinsing preoperatively and 7 days postoperatively, seem to have significant and clinically relevant preventive effect on AO following surgical removal of lower third molars.

Anti-Bacterial Agents↗
PubMed2001

[Condition of patients after surgical wisdom tooth extraction under general anesthesia with different premedication variants--a prospective study based on a post-anesthesia questionnaire].

Evaluation of the modified "postanaesthesiological questionnaire" pointed to a subtle influencing of the condition of patients who had undergone 3rd molar surgery in general anaesthesia by using different premedication variants: "Atropine, Pethidine and Midazolam" (group A) and "Atropine, Midazolam and S-Ketamin" (group B). The combination in group B seems to be more suitable. On the one hand, a lower incidence of unwanted side-effects was found and, on the other hand, remarkable positive effects were observed. Of particular significance with this combination was also the more effective suppression of postoperative pain. The Propofol-supplemented general anaesthesia prepared in this way and administered using a nasal intubation technique found the full approval of the patients. Postoperative pain therapy was effective and also inexpensive, costing just 8.20 DM per patient, according to current prices calculated by Magdeburg University Hospital.

Adult↗
PubMed2006

Histological and histomorphometrical changes in rat alveolar bone following antagonistic tooth extraction and/or ovariectomy.

OBJECTIVE: To examine changes appearing in the alveolar bone following the removal of the mechanical stress of occlusal loading, as well as the added influence of estrogen deficiency on such changes. DESIGN: The right mandibular molars of female rats were extracted. After 8 weeks, 12 animals were ovariectomized (OVX), and the other 12 were subjected to sham surgery (sham). Four weeks after surgery, all rats were sacrificed. The left-half and right-half maxillas of the sham group (the sham-occluded side and the sham-extruded side, respectively) and right-half maxilla of OVX group (the OVX-extruded side) were examined by histological observation and bone histomorphometry. RESULTS: The vertical height of alveolar bone in the sham-extruded and the OVX-extruded sides increased as compared with that of the sham-occluded side. In both extruded sides, active bone formation occurred on the surface of the alveolar bone facing the periodontal ligament, but the bone marrow was expanded and the bone volume had decreased in the internal area of the alveolar bone. In the OVX-extruded side, the bone marrow expanded more remarkably than that of the sham-extruded side, and the highest percentage of osteoclast surface was detected. CONCLUSIONS: Around the extruded teeth, there were regional differences in bone dynamics between the internal area of the alveolar bone and the bone surface facing the periodontal ligament, and estrogen deficiency seems to have caused further loss of bone volume in the interior of the alveolar bone supporting the extruded tooth.

Acid Phosphatase↗
PubMed1981

[Vivisection studies on the effects of unilateral tooth extraction on growth of the skull amd masticatory musculature (author's transl)].

Following up on the 1st part of this cycle of publications, the 2nd Bulletin deals with investigations on upper and lower jaw growth in the Vietnamese belly pig after extracting all teeth as they appeared in the right half of the jaw. The results showed characteristic changes on the side of the extraction compared with the skull on the other side. They also show clearly that the effects of unilateral loss of teeth on the development of the bony part of the chewing apparatus are very local. This is made evident by analysis distances measured for the 3rd and 4th upper jaw widths and the 2nd vertical height of the bottom jaw. In contrast to other authors, we found no changes in the longitudinal and lateral development of the bottom jaw. Due to the slight degree of development of the alveolar process of the bottom jaw in the region of the 1st permanent molar, a significant reduction in surface area was found when removing the 2nd molars, which was performed usually at an early point, only in the group slaughtered after 12 months.

Animals↗