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At least 883 records · Page 49Linked to original sources
PubMed1994

5-HT1A and muscarinic acetylcholine receptors jointly regulate passive avoidance behavior.

The present study was designed to investigate the effects of combined stimulation of 5-HT1A or 5-HT2 receptors and blockade of muscarinic acetylcholine receptors on passive avoidance behavior. Administration of 8-hydroxy-2-(di-n-propylamino)tetralin (8-OH-DPAT), a 5-HT1A receptor agonist, and 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI), a 5-HT2 receptor agonist, impaired passive avoidance acquisition (pre-training injections) and consolidation (post-training injections) performance. Ketanserin, a 5-HT2 receptor antagonist, blocked the performance-impairing effect of DOI on passive avoidance consolidation. Interestingly, 5-HT receptor agonists may affect passive avoidance consolidation only during the immediate post-training period, as passive avoidance testing performance was not modulated by 8-OH-DPAT or DOI injected 30 min after the training trial. Furthermore, passive avoidance retention (pre-testing injections) performance was impaired only by the highest dose of 8-OH-DPAT, and DOI had no effect on passive avoidance retention. Next, the effects of combined 5-HT and acetylcholine receptor manipulations on passive avoidance behavior were studied. The effects on passive avoidance behavior of a combination of subthreshold doses of scopolamine, a muscarinic acetylcholine receptor antagonist, and 8-OH-DPAT were compared to those of a single high dose of scopolamine. A combination of small doses of scopolamine and 8-OH-DPAT impaired acquisition and consolidation of passive avoidance performance, but a single high dose of scopolamine impaired only acquisition performance. The small dose of 8-OH-DPAT also aggravated medial septal lesion-induced passive avoidance acquisition and consolidation failure. The combination of small doses of scopolamine and DOI had no effect on passive avoidance behavior. Peripherally acting scopolamine methylbromide alone or in combination with 8-OH-DPAT had no effect on passive avoidance performance. Motor activity in a swimming pool was altered by single and combined drug treatments; high doses of 8-OH-DPAT and scopolamine, and the combination of small doses of 8-OH-DPAT + scopolamine increased speed of swimming. Medial septum-lesioning also increased speed of swimming but the speed was not increased further by 8-OH-DPAT. The present data suggest that behavioral defect caused by hypostimulation of muscarinic acetylcholine receptors is aggravated by concurrent 5-HT1A receptor stimulation.

8-Hydroxy-2-(di-n-propylamino)tetralin↗
PubMed1975

Bradycardia during human diving.

The bradycardial response to the diving reflex, which occurs in man and in diving animals, is thought to be a physiologically protective oxygen-conserving mechanism whereby the animal is kept alive during submergence. The physiology and nervous pathways are not yet fully understood, but several investigators have pointed out the potentially fatal outcome of an accentuated diving reflex. the CO2 content of the peripheral venous blood has been proved variable and unpredictable during the hyperventilation-breath-hold dive cycle in man. A group of 8 male divers (average age 34 years) was investigated during breathhold dives to 3,3 m in a swimming pool. Heart rates were recorded and compared at various stages during breath-hold and SCUBA (self-contained underwater breathing apparatus) dives, viz. when resting on the surface, breath-holding, hyperventilating and swimming underwater. Two divers performed extreme breathhold endurance tests lasting 135 seconds underwater. All divers had a tachycardia after hyperventilation and a bradycardia after breathhold diving, lasting 80-100 seconds. Extrasystoles were recorded during some of the breathhold dives. Prolonged submergence caused extreme bradycardia (24/min) with central cyanosis. Bradycardia during diving may be a physiological )2-conserving reflex or the start of a pathophysiological asphyxial response.

Adult↗
PubMedDate not supplied

Illness and absence among wrestlers, swimmers, and gymnasts at a large university.

The object of this study was to document the prevalence of illness and absence in members of three men's intercollegiate athletic teams: varsity wrestling, swimming, and gymnastics. Team members (N = 87) were interviewed weekly in January and February during 8 weeks of their competitive season. Symptoms, signs, and their duration were recorded on a standard form, as well as the number of days of absence from at least one class or team practice or competition. Mean prevalence of illness was 54 per 100 persons during the first 5 weeks of the study and 30 per 100 persons during the last 3 weeks. Eight-six percent of the athletes had at least one respiratory illness during the 8 week period and 40% reported skin problems. There were no significant differences among teams for respiratory or skin problems. Gastrointestinal symptoms were significantly more frequent among swimmers than among wrestlers or gymnasts (chi 2 = 16.1, df = 2, P less than 0.001). During an illness, an athlete was less likely to miss class than practice or competition (chi 2 = 5.33, df = 1, P less than 0.05). We conclude that there were no significant differences in the prevalence of illness among the three teams except that swimmers had more gastrointestinal problems as well as a transient syndrome associated with abnormal water quality (pH) in the swimming pool.

Absenteeism↗
PubMed1997

Blocking in the spatial domain.

An initial series of experiments with rats in a swimming pool established that they could find a hidden platform the location of which was defined in terms of 3 or 4 landmarks and that, when trained with all 4, any subset of 3 (or even, after a sufficient number of swimming trials, 2) landmarks was sufficient to produce accurate performance. When only one landmark was present during testing, however, performance fell to chance. Two additional experiments demonstrated a significant blocking effect: If rats were first trained to locate the platform with 3 landmarks, they did not learn to use a 4th landmark added to their initial set of 3.

Animals↗
PubMed1993

Blood lactate accumulation in top level swimmers following competition.

The purposes of this study were to evaluate the significance of blood lactate values after competitions and the blood lactate-swimming speed relationship to swimming performances. Auricular blood samples (N = 421) were collected in 203 top level Italian swimmers (116 males and 87 females) at the end of competitions performed in a 25 m swimming pool. The distribution of all lactate values differed between males and females. The lowest lactate values occurred in swimmers performing the longest distances both in males (1500 m) and females (800 m). In swimmers performing freestyle events a relationship between V-4 mM (swimming speed at 4 mmol/l blood lactate value) and competition velocities was observed, in males, at 200, 400 and 1500 m and, in females, at 400 and 800 m. The predicted velocity corresponding to the competition lactate value assessed by the individual blood lactate-swimming speed relationship was found to be highly related to the actual competition velocity. Results suggest that blood lactate values in swimmers are a useful indication of individual aptitudes.

Adolescent↗
PubMed1992

Validity of critical velocity as swimming fatigue threshold in the competitive swimmer.

The purpose of this investigation was to determine whether the critical velocity (CV) as the swimming speed which can be theoretically maintained for a very long time without exhaustion could be applied to estimate the swimmer's endurance performance. CV was based on the concept of critical power originality established by Monod and Scherrer (1965) and extended by Moritani et al. (1981), and expressed as the slope of a regression line between swimming distance (D) at each velocity and its sustained time (T). Seventeen highly trained swimmers were instructed to swim the four different swimming distances (50 m, 100 m, 200 m and 400 m) at maximal effort using the swimming pool. In the results of CV, the regression relations between D and T were expressed in the general form, D = a + bxT, with r2 showing higher than 0.997 (p less than 0.001). These results indicate extremely good lineality. Furthermore, VO2max during incremental exercise test, swimming speed corresponding 4 mM of blood lactate concentration (V-OBLA) and mean velocity in the 200 m and 400 m freestyle (V-200 and V-400) were measured on nine subjects. Significant correlations were found between CV and V-OBLA (r = 0.862, p less than 0.01), CV and V-200 (r = 0.781, p less than 0.01), CV and V-400 (r = 0.999, p less than 0.001), V-OBLA and V-400 (r = 0.869, p less than 0.01) and V-200 and V-400 (r = 0.776, p less than 0.01).(ABSTRACT TRUNCATED AT 250 WORDS)

Competitive Behavior↗
PubMed2004

Sequential control of navigation by locale and taxon cues in the Morris water task.

The neurobehavioral dissociation between place navigation and cued navigation has been central to contemporary thinking regarding the psychological processes involved in spatial behavior. In cases where locale (place) cues and taxon cues (e.g., beacons) are present it has been suggested that navigation may be controlled by either stimulus type in isolation, or, alternatively, by both simultaneously. In this report we provide evidence that place cues and beacons sequentially control navigation during a single trip to a visible goal. Rats were trained to navigate to a visible escape platform in a circular swimming pool surrounded by numerous visual cues and the kinematics and accuracy of the trajectories to the platform were analyzed. Shortly after initiating a trajectory to the visible platform, animals routinely engaged in stimulus sampling behaviors (e.g., horizontal head scans) which were consistently associated with changes in accuracy (heading error) and swim velocity. Subsequently, animals swam quickly and accurately to the visible platform suggesting that the sampling behaviors correspond to a shift in exteroceptive stimulus control. Consistent with this idea, removal or relocation of the platform disrupted navigation following the stimulus sampling behaviors, whereas the initial trajectory was unaffected. In contrast, changes in the distal cue constellation selectively disrupted the initial trajectory. The results showing that navigation to a visible goal is controlled sequentially by locale and taxon cues are discussed in relation to contemporary theories of navigation.

Animals↗
PubMed1993

Epilepsy in children and the risk of drowning.

To clarify the risks of drowning for children with epilepsy we have studied the records of the 306 children who drowned or nearly drowned in the UK in 1988 and 1989. Ten children with incidents related to epilepsy presented over the study period, four of whom drowned. Children with epilepsy had a higher incidence of submersion accidents but no child participating in supervised swimming drowned. Two children died in the bath. Five children had special needs. We conclude that children with epilepsy can enjoy swimming with a friend in a lifeguard supervised swimming pool. They should be encouraged to shower in a non-glass cubicle rather than have a bath. The bathroom should remain unlocked. Children with poorly controlled epilepsy or associated learning difficulties are at a higher risk from all accident trauma. They need a very high level of supervision while swimming and advice should be given on an individual basis according to what is considered realistic for that child.

Adolescent↗
PubMed2003

Prediction of sprint triathlon performance from laboratory tests.

This study investigated whether sprint triathlon performance can be adequately predicted from laboratory tests. Ten triathletes [mean (SEM), age 21.8 (0.3) years, height 179 (2) cm, body mass 67.5 (2.5) kg] performed two graded maximal exercise test in random order, either on their own bicycle which was mounted on an ergometer or on a treadmill, to determine their peak oxygen consumption ( VO(2)peak). Furthermore, they participated in two to three 30-min constant-load tests in both swimming, cycling and running to establish their maximal lactate steady state (MLSS) in each exercise mode. Swim tests were performed in a 25-m swimming pool (water temperature 27 degrees C). During each test heart rate (HR), power output (PO) or running/swimming speed and blood lactate concentration (BLC) were recorded at regular intervals. Oxygen uptake ( VO(2)) was continuously measured during the graded tests. Two weeks after the laboratory tests all subjects competed in a triathlon race (500 m swim, 20-km bike, 5-km run) [1 h 4 min 45 s (1 min 38 s)]. Peak HR was 7 beats.min(-1) lower in the graded cycle test than in the treadmill test ( p<0.05) at similar peak BLC (approximately 10 mmol.l(-1)) and VO(2)peak (approximately 5 L.min(-1)). High correlations were found between VO(2)peak during cycling ( r=-0.71, p<0.05) or running ( r=-0.69, p<0.05) and triathlon performance. Stepwise multiple regression analysis showed that running speed and swimming speed at MLSS, together with BLC in running at MLSS, yielded the best prediction of performance [1 h 5 min 18 s (1 min 49 s)]. Thus, our data indicate that exercise tests aimed to determine MLSS in running and swimming allow for a precise estimation of sprint triathlon performance.

Adult↗
PubMed1992

Water way to lose weight.

Many severely overweight women find it difficult to follow conventional exercise programmes. Salisbury health visitors Rosalind Griffith and Pauline Sharp run weekly 'Swim-slim' sessions at the local hospital swimming pool where overweight women, too embarrassed to go to their local baths on their own, exercise together to lose weight and gain confidence to tackle social isolation and depression.

Body Image↗
PubMed2001

Recreational water safety in Wisconsin.

Due to Wisconsin's numerous lakes and rivers, tourists and residents alike frequently participate in water-related recreation. Unfortunately, drowning is a leading cause of injury-related death, especially in children and young adults. Developmental factors place children who are less than 5 years at increased risk for drowning. Teenagers also have a higher drowning mortality rate, largely due to risk-taking behaviors in this age group. This article reviews drowning mortality trends and statistics for Wisconsin and the United States, as well as current recommendations and legislation regarding water safety. We also discuss drowning prevention strategies such as patient education and legislative efforts surrounding swimming pool and boating safety.

Adolescent↗
PubMedDate not supplied

Infant's physiological response to short heat stress during sauna bath.

Thermoregulatory response to Finnish sauna bath was investigated in 47 infants (age 3 - 14 month). Before taking a short sauna bath lasting 3 min, the infants stayed in a swimming pool for 15 min. Under these conditions sauna bathing did not increase the rectal temperature. Unexpectedly rectal temperature even decreased by 0.2 degrees C (p < 0.05) probably due to redistribution of cold peripheral blood into the core of the body. Mean systolic and diastolic arterial blood pressure and mean heart rate remained unchanged after sauna bathing. The blood pressure amplitude decreased significantly after the swimming period from 47 mm Hg to 38 mm Hg (p < 0.05) and rose again after sauna bathing to 42 mm Hg. All infants tolerated short heat exposure in the sauna without side effects. The circulatory adjustment was efficient. Even young infants were able to cope with the acute circulatory changes imposed by heat stress. Adequate thermoregulatory and cardiovascular adaptive responses to sauna bathing could be shown for the first time in infants between 3 and 14 months of age.

Age Factors↗
PubMed2005

Ear problems in swimmers.

Acute diffuse otitis externa (swimmer's ear), otomycosis, exostoses, traumatic eardrum perforation, middle ear infection, and barotraumas of the inner ear are common problems in swimmers and people engaged in aqua activities. The most common ear problem in swimmers is acute diffuse otitis externa, with Pseudomonas aeruginosa being the most common pathogen. The symptoms are itching, otalgia, otorrhea, and conductive hearing loss. The treatment includes frequent cleansing of the ear canal, pain control, oral or topical medications, acidification of the ear canal, and control of predisposing factors. Swimming in polluted waters and ear-canal cleaning with cotton-tip applicators should be avoided. Exostoses are usually seen in people who swim in cold water and present with symptoms of accumulated debris, otorrhea and conductive hearing loss. The treatment for exostoses is transmeatal surgical removal of the tumors. Traumatic eardrum perforations may occur during water skiing or scuba diving and present with symptoms of hearing loss, otalgia, otorrhea, tinnitus and vertigo. Tympanoplasty might be needed if the perforations do not heal spontaneously. Patients with chronic otitis media with active drainage should avoid swimming, while patients who have undergone mastoidectomy and who have no cavity problems may swim. For children with ventilation tubes, surface swimming is safe in a clean, chlorinated swimming pool. Sudden sensorineural hearing loss and some degree of vertigo may occur after diving because of rupture of the round or oval window membrane.

Acute Disease↗
PubMed1998

Respiratory symptoms, bronchial responsiveness, and cellular characteristics of induced sputum in elite swimmers.

To investigate respiratory symptoms, increased bronchial responsiveness, and signs of airway inflammation in elite swimmers, we examined 29 swimmers from the Finnish national team and 19 healthy control subjects (nonasthmatic, symptom-free). They answered a questionnaire and were interviewed for respiratory symptoms. Lung volumes were measured and bronchial responsiveness assessed by a histamine challenge test. Induced sputum samples were also collected. Fourteen (48%) of the swimmers and three (16%) of the control subjects showed increased bronchial responsiveness (P<0.05). The sputum cell differential counts of eosinophils (mean 2.7% vs 0.2%) and neutrophils (54.7% vs 29.9%) from swimmers were significantly higher than those from controls (P<0.01). Eosinophilia (sputum differential eosinophil count of >4%) was observed in six (21%) of the swimmers and in none of the controls (P<0.05). Symptomatic swimmers had significantly more sputum eosinophils than did the symptom-free. The concentrations of sputum eosinophil peroxidase (EPO) and human neutrophil lipocalin (HNL) were significantly higher in swimmers than control subjects (P<0.001 and P=0.05). We conclude that elite swimmers had significantly more often increased bronchial responsiveness than control subjects. Sputum from swimmers contained a higher percentage of eosinophils and neutrophils, and higher concentrations of EPO and HNL than sputum from controls. Long-term and repeated exposure to chlorine compounds in swimming pools during training and competition may contribute to the increased occurrence of bronchial hyperresponsiveness and airway inflammation in swimmers.

Adolescent↗
PubMed1987

Impairments in the acquisition, retention and selection of spatial navigation strategies after medial caudate-putamen lesions in rats.

Using the Morris swimming pool test of spatial navigation, medial caudate-putamen lesions in rats produce impairments in the acquisition and retention of both place and cue tasks, and impair the selection of normal navigation strategies. Also described are some novel features of spatial navigation behaviour displayed by control animals in cue and place tasks that provide insights into the performance of the caudate-putamen rats. Analyses of the swim patterns on postacquisition probe trials, in which the target platform was removed or relocated, showed that the strategy used by the caudate-putamen lesioned rats was dependent upon the task that they were required to solve. Control rats used a place strategy and distal visual cues to identify the location of the start points, the routes from the start points to the platform, and the location of the platform on both the cue and place tasks. The caudate-putamen lesioned rats used distal visual cues and a place strategy only to acquire the place task. They solved the cue task using a taxon strategy consisting of a combination of proximal and position response cues. The results suggest that when necessary, medial caudate-putamen lesioned rats, like normal rats, can use place strategies for spatial navigation, but if an alternate, perhaps simpler, taxon solution is available they seemingly ignore place information and navigate using the simpler strategy. The deficit, which has features of a neglect rather than a loss of ability per se, suggests that medial caudate-putamen neural systems are involved in the selection of alternative strategies in spatial navigation tasks.

Afferent Pathways↗
PubMed2003

Effects of positive GABA(A) modulators on a multiple-component, repeated-acquisition test of spatial learning.

The purpose of this study was to determine the effects of the benzodiazepines, midazolam and chlordiazepoxide, and the barbiturate, pentobarbital, on spatial learning, in a within-subject, repeated-acquisition and performance procedure adapted to the Morris Swim Task. In the presence of one stimulus arrangement, rats learned to swim to a hidden escape platform that was always in the same location in a swimming pool (performance component). In the presence of a second stimulus arrangement, the platform moved to a different place in the pool for each daily session (acquisition component). All subjects completed six training trials in both components during each daily training session, alternating between the two components within each session. Relatively direct paths to the platform and short escape latencies in the performance component, and steep within-session learning curves in the acquisition component, demonstrated that behavior under each component was controlled by the discriminative stimuli. All three GABA(A) modulators increased swim distances, escape latencies, and slowed swim speed in a dose-dependent manner. Midazolam and chlordiazepoxide, but not pentobarbital, produced selective impairments of swim distances and escape latencies in the acquisition component. Benzodiazepines disrupted acquisition at doses that did not disrupt steady-state performance. Pentobarbital impaired acquisition only at doses that also disrupted behavior during the performance component and reduced swimming speeds.

Animals↗
PubMed1989

The occurrence of cercarial dermatitis in Central Bohemia.

The occurrence of a dermatitis was reported from 4 natural water reservoirs in Central Bohemia (Czechoslovakia) in June and August 1985 and 1986. The clinical course of the disease was suggestive of cercarial dermatitis. Exanthema occurred most frequently under the bathing suits of afflicted persons, and on unprotected parts of their skin as well. A total of 5,865 snails (Lymnaea auricularia) were collected at the localities Nový rybník in Príbram, Spálený mlýn at Lísnice and Uhonice. Nine individuals of L. stagnalis were collected at Grado, Celákovice. Biological examination indicated cercariae of bird schistosomes (Trichobilharzia szidati) only at one locality--Spálený mlýn, Lísnice. The question of cercarial dermatitis caused by species other than schistosome cercariae, especially by Diplostomum spathaceum which was abundant at Príbram, is discussed. Repeated outbreaks of cercarial dermatitis were stopped at one locality by chemical and mechanical snail control in a swimming pool. Chemical control by chlorinated lime and copper sulfate proved insufficient in the course of the season. The mechanical control (clearing of the mud and drying of the bottom of the pool) removed infected snails, reservoirs of the disease. Suggested changes in the composition of fish fauna should also reduce excessive reproduction of snails.

Animals↗