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Long-term evidence for favorable midfacial growth after delayed hard palate repair in UCLP patients.

OBJECTIVE: To investigate whether delayed hard palate repair resulted in better midfacial growth in the long term than previously achieved with "conventional" surgical methods of palatal closure. DESIGN AND SETTING: Long-term cephalometric data from patients with unilateral cleft lip and palate were available from two Scandinavian cleft centers. The patients had been treated by different regimens, particularly regarding the method and timing of palatal surgery. Patients were analyzed retrospectively, and one investigator digitized all radiographs. PATIENTS: Thirty consecutively treated subjects from each center, with cephalograms taken at three comparable stages between 10 and 16 years of age. RESULTS AND CONCLUSIONS: Patients whose hard palates were repaired late (early soft palate closure followed by delayed hard palate repair at the stage of mixed dentition) had significantly better midfacial development than patients in whom the hard palate was operated on early with a vomer flap, and then during the second year of life, the soft palate was repaired with a push-back procedure. As the growth advantage in the delayed hard palate repair group was accomplished without impeding long-term speech development, the delayed repair regimen proved to be a good alternative in surgical treatment of patients with unilateral cleft lip and palate.

Adolescent↗

Post-traumatic TMJ internal derangement: impact on facial growth (findings in a pediatric age group).

Many clinical studies have shown how jaw injuries sustained during impact trauma to the face or mandible are the single most important cause of TMJ subsequent internal derangement. Proper function of the masticatory system is certainly the most influential variable in the TMJ remodelling; once a TMJ is internally deranged, adaptative or degenerative osteocartilagineous processes take place in the mandible, temporal bones and muscles. To evaluate relationships between consequences of post-traumatic TMJ internal derangement and disturbed facial skeleton growth in children, 25 patients (16 boys 9 girls), 14 year of age or younger, were selected out of a group of 74 and analysed. They all had been treated by physiotherapy and had undergone combined clinical and radiographic examination for five years. Symptoms included either individually or in various combination, pain, mechanical TMJ dysfunction and facial skeletal abnormalities, such as mandibular retrognathia and lower facial asymmetry manifested by chin deviation from the midline. Seventeen patients were found to have at least one abnormal and internally deranged TMJ on imaging studies; in twelve of them a mandibular asymmetry with chin deviation from the midline to the smaller or more degenerated TMJ was evident. Of the eight retrognathic patients, five were found to have bilateral TMJ derangement. In three patients both TMJ(s) were normal with normal facial structure. These data suggest that TMJ derangement in children may potentially have an impact on facial growth and lead to the development of retrognathia, with or without asymmetry, in many cases.

Adolescent↗

[On the influence of the time of surgical operation upon dentural development in the case of gnathoplasty, palatoplasty, and uraniscoplasty with simultaneous osteoplasty (author's transl)].

In patients with cheiloschisis, gnathoschisis, palatoschisis, and uranoschisis, who underwent plastic operations when between four and six years old, maxillary models were biometrically analyzed in the tenth and eleventh years of age. It has been found that the different choice of the time of reparative operation has no influence whatsoever upon maxillary development during childhood. This is of great practical importance especially from a phoniatric and logopedic point of view.

Age Factors↗

[Radiographic study of the development of the permanent dentition of Brazilian children with a chronological age of 84 and 131 months].

With the help of orthopantomograms we analyse the tooth development beside body weight and height from Brazilian healthy boys and girls. So, their dental age were compared to their chronological age. The results of this investigation, according to the methodology employed, indicated that: 1. girls showed accelerated formation of permanent teeth and mean values of dental age higher than boys; 2. the mean values of dental age in girls were higher than their chronological age in all groups; 3. the teeth development stages were appropriate in assessment of the degree of physiological maturity of a growing child.

Body Height↗

[Dental age evaluation in young subjects with Cooley's disease].

The AA. have evaluated dental age in growing subjects with Cooley's anemia. 34 patients aged from 4 to 11.8 years were clinically examined as far as the number of teeth erupted. Dental arches x-rays were taken for each patients to evaluate dental age according to dental development. From the data collected in our investigation it comes out that there were no difference between dental age and chronological age.

Age Factors↗

Early orofacial development.

Early orofacial development is a period of very rapid allometric growth and specialization of tissue. During the first three years of life, the brain achieves approximately 90% of its growth and the face reaches almost 65% of its adult size. Between birth and three years of age the oral cavity changes form and function, replacing gum pads with a dentition composed of twenty primary teeth. By three years of age, all succedaneous teeth are developing as well as the first permanent molars. Involvement with neonates and infants by neonatologists, pediatricians, and pediatric dentists begs a better appreciation of this rapidly changing period.

Child, Preschool↗

Developmental changes in the shape of the supralaryngeal vocal tract in chimpanzees.

The hyoid bone and larynx in human neonates are positioned as high as in other mammals. However, during postnatal life, they descend relative to the hard palate more rapidly compared with the horizontal growth of the oral cavity. This process is completed through the descent of the laryngeal skeleton relative to the hyoid, and through the descent of the hyoid relative to the cranial base. Thus, the human supralaryngeal vocal tract (SVT) develops to form a two-tube configuration with equally long horizontal and vertical parts. Longitudinal studies on living chimpanzee infants show that the descent of the larynx is more rapid than the horizontal growth of the oral cavity. This is primarily attributed to the descent of their larynges relative to the hyoid bone, but this is not accompanied by the descent of the hyoid. The present study, using embalmed specimens of chimpanzees, also shows that the horizontal and vertical parts of the SVT grow in chimpanzees similarly to humans during infancy. However, in chimpanzees, the horizontal part of the SVT grows greatly, whereas the vertical part of the SVT grows only slightly during the juvenile period. As a result, the chimpanzee larynx does not descend rapidly relative to the oral elongation during that period. Such differences may be related to the structural and morphological development of the facial skeleton and mandible, which affects prognathism and hyoid descent. These results support the hypothesis that the descent of the larynx evolved in at least two steps during hominoid evolution.

Animals↗

Implications of temporomandibular disorders for facial growth and orthodontic treatment.

The purpose of this article is to review the literature concerning the possible associations between temporomandibular disorders (TMD), orthodontic therapy, mandibular growth, and facial form. Consideration of the association between TMD and orthodontic treatment leads to one conclusion: there is no evidence that orthodontic treatment generally increases or decreases the chances of developing TMD later in life. Still, our understanding of TMD is not final, and the expanding diagnostic knowledge continues to call for new longitudinal studies focusing on the developmental basis of temporomandibular disorders. Little is known about the potential effect of TMD on facial development. However, information relating to the normal development, growth, and adaptation of the temporomandibular joint all tend to emphasize the significant ontogenetic plasticity of the growth-related secondary cartilage associated with the TMJ, within the bounds of normal function and histophysiology. With the exception of such diseases as juvenile rheumatoid arthritis and osteoarthritis, little is known about the influence of TM pathology or myofascial disorders on facial growth. Also, little is known about the possible influence of disc interferences on facial growth. However, the condyle is known to play a prominent role in normal mandibular growth and, consequently, facial development. Thus, categories of TMD that involve dysplasia of the condylar cartilage could be associated with aberrant facial growth and form.

Adolescent↗

The aetiology of Class III malocclusion examined by tensor analysis.

This study compares and contrasts the differences in facial pattern between groups of young people, employing a modified tensor analysis. One-hundred-and-thirty-eight children with Class III malocclusions were compared with 105 control individuals of similar ages: 126 subjects were prepubertal (age range 7 to 10 years), whilst the remaining 117 were between 15 and 22 years of age. Males and females were examined separately. The tensor analysis permitted the computation of differences in form (that is in size and shape) without specifically measuring either. Mean values for 18 conventional cephalometric landmarks were determined for each sub-group of control and Class III individuals. Customized programs were developed to assess the differences between 23 triads of points between the two occlusal groups.

Adolescent↗

Facial growth of males and females compared by tensor analysis.

This study compares and contrasts the longitudinal differences in facial development between 18 male and 22 female subjects, employing the technique of tensor analysis. Children were examined in two age ranges: prepubertal (aged 7-10 years) and post-pubertal (15-20 years of age). Both the changes over time and the differences in amount and direction of growth between the sexes were subjected to statistical analysis. A tensor analysis permits the computation of differences in form (that is in size and shape) without specifically measuring either. Mean values for 21 hard and soft tissue landmarks were determined for both males and females at each age. Customized computer software allowed examination of the growth changes between 32 selected groups of points. Results indicated that the tensor analysis reinforced and supplemented the more conventional descriptions of facial growth. Females grew a smaller amount over the period examined than their male peers and development was in a relatively more vertical direction. These differences in growth between the sexes were highly statistically significant.

Adolescent↗

Selectively preventing development of third molars in rats using electrosurgical energy.

BACKGROUND: Third molars are teeth with questionable value. People who never develop third molars avoid confronting the disease and pain these teeth often cause. Since third molars do not begin to develop until children are approximately five years of age, a window of opportunity exists to therapeutically prevent this tooth's development. The dentition of neonate rats possess developmental stages of molars similar to that of five-year-old children. This pilot study tests the hypothesis that third molars can be selectively prevented from developing. METHODS: Thirty-three neonate rats received a momentary pulse of electrosurgical energy to one of their maxillary tuberosities. The tuberosities on the contralateral sides received no treatment. Intraoral and radiographic examinations of sacrificed animals occurred when they were between 47 and 52 days old. Several tuberosity areas from sacrificed animals underwent histologic examination. RESULTS: Ten rats showed no intraoral or radiographic evidence of third molar development, and six developed smaller-than-normal third molars. Development of the maxilla also was affected frequently. One treated tuberosity area that was missing a third molar showed no histologic evidence of tooth-forming tissues, cyst formation or other significant abnormal tissue changes. CONCLUSIONS: Maxillary third molars can be selectively prevented from developing in rat pups at or near the time of tooth bud initiation; however, electrosurgical energy is too powerful and uncontrollable to reliably confine its damage to only the tooth-forming tissues. CLINICAL IMPLICATIONS: Third molars may be able to be selectively prevented from developing in growing children near the time of tooth bud initiation if less-differentiated precursor tooth-forming tissues can be selectively targeted.

Animals↗

Mandibular asymmetry and antigonial notching in individuals with unilateral cleft lip and palate.

OBJECTIVE: To determine whether asymmetric antigonial notching is associated with the development of mandibular and lower facial asymmetry in individuals with unilateral cleft lip and palate (UCLP). DESIGN: Retrospective mixed-longitudinal investigation including UCLP and nonaffected orthodontic patients. PARTICIPANTS: All (24) available patients with UCLP treated in our clinic with complete longitudinal records, and 72 skeletal maturation matched noncleft orthodontic patients that served as controls. Subject records included hand-wrist, panoramic, frontal, and 45 degrees oblique cephalometric radiographs. MAIN OUTCOME MEASURES: The development of mandibular asymmetry, measured on oblique cephalometric radiographs, as well as lower facial asymmetry, measured on frontal cephalometric radiographs, was monitored in individuals with UCLP in relation to antigonial notching asymmetry, assessed on panoramic and oblique cephalometric radiographs. RESULTS: First, no statistical differences were found in antigonial notching asymmetry between patients with UCLP and noncleft controls. Second, antigonial notching asymmetry, observed on panoramic and oblique cephalometric radiographs, significantly correlated with the attendant development of mandibular and lower facial asymmetry in individuals with UCLP. Third, the development of mandibular and lower facial asymmetry at pubertal and postpubertal growth spurt stages significantly correlated with antigonial notching asymmetry, measured on panoramic radiographs, at prepubertal and pubertal growth spurt stages, respectively. CONCLUSIONS: The degree of antigonial notching noted on panoramic radiographs can be used as an early indicator of developing mandibular and lower facial asymmetry in individuals with UCLP.

Adolescent↗

[Plea for the application of statistical methods by computer to stomatological research].

In face of the double reflex of fascination and defiance which is right away created by statistical methods by computers, the authors have attempted by means of precise examples to demystify these methods by recalling: 1) That computer statistics can be defined as the association of a service and a machine, the combination should be considered as an instrument and only an instrument. 2) That the application of computer statistics to odonto-stomatological research of course evidently enables the resolution of problems which would be otherwise insoluble, but above all considerably enlarges the field of research by rendering visible phenomena which would otherwise remain hidden. In this way, statistical methods by computer can be compared with the microscope; a low magnification with the optical microscope justifies only an overall view of the section while changing to higher magnifications permits the demonstration of details which would remain unsuspected. Use of the electromicroscope opens up another world for research. 3) In the same way as the biologist who uses the microscope, if he knows the principle of it is not in so far a specialist in optics, neither does the research woker who uses statistics necessarily have to be a trained statistician, on the one condition that evidently he disposes of professional computer logistics. This is the case of the ACB (Nantes) rush technical units, who cosigned this work, where the engineers who pose the problems to be resolved and emit the working hypotheses from the results supplied by the statistical studies are not the same people who carry out these very studies. 4) An essential fact, the research worker's independance is complete, only he can pose the problems and emit the hypothesis from the correlation, i. e. point of fact concomitance between the various isolated parameters. It therefore does not seem that weighty statistical techniques presently occupy the place of choice which should be theirs in stomatological research and more particularly in research concerning growth and development of the face where their use seems to be electively implied in face of the number and complexity of the parameters looked at.

Computers↗

[Results from a study of the normal values in the vertical, sagittal and transversal plane of early mixed dentitions].

168 (21.7%) of 776 pupils from primary classes in Jena had normal tooth position and occlusion. 94 of them were selected for a longitudinal study. Up to now, they have been examined at the ages of 7 and 8 years. The evaluation of the results obtained showed differences with regard to age and sex. The data reported and the deviations observed may be considered reference values. They concrete the assessment of the growth and development in the orofacial system, facilitate the recognition of dysgnathias which must be treated and optimize the planning and performance of orthodontic treatment.

Cephalometry↗

Orofacial myofunctional disorders in children with asymmetry of the posture and locomotion apparatus.

352 children radiologically identified with asymmetry in the occipito-cervical region were assessed on a number of myofunctional measures. In all children an orthopedic examination was conducted including a functional test of the upper cervical spine and the iliac joint, the postural test by Matthiass, as well as gait analysis. During a second examination the orofacial myofunctional status was recorded. In general, about 70% of the children revealed orofacial myofunctional disorders. Correlational analysis was conducted in order to determine whether specific myofunctional variables were associated with postural and orthopedic alterations. A weak body posture correlated statistically significantly with all assessed myofunctional variables. On the other hand, all orthopedic items correlated significantly with a reclined head position. A blockade of the iliac spine correlated significantly with persistent habits, articulation disorders and tongue dysfunction, whereas functional asymmetry of the upper cervical spine correlated significantly with incompetent lips. A finding of at least five statistically significant correlations within each orofacial variable underlined the complex symptomatology of myofunctional disorders, so that consideration needs to be given to adequate treatment approaches. The data generated by the present study stress the importance of early interdisciplinary screening in children to ensure a physiological development of the orofacial region and the still growing vertebral column. To help understand the complexity of symptoms influencing orofacial development, an explanatory model of the "interactive functional box system" is given.

Adolescent↗

Variation in function of the masticatory system in 1008 rural children.

The aim on the present study was to investigate the variation in function of the masticatory system in 1008 subjects 5 to 15-years-old in a rural community. This study considered the effects of age, gender, developmental stage of the dentition and interexaminer variability. In addition, maximal opening capacity of the mandible was assessed in relation to age, gender and body size. Four dentists performed the examinations combined with routine check-ups, preventive and operative dental treatments. The results showed that the opening capacity in children increases from the age of 6 to the age of 12 with no difference between the sexes. Children of bigger size seem to have larger opening than the smaller ones. Minor differences were found between the sexes, but some variation with age could be seen in signs of craniomandibular disorders (CMD) and in occlusal recordings. Children with RP-IP slide had more often CMD-signs than the ones without this occlusal feature mainly from the instability of occlusion. This is in accordance with the finding of a higher prevalence of muscle tenderness and mediotrusion interferences during the mixed dentition. In general, in children expression of the craniomandibular disorders seems to reflect physiological changes during development of the dentition and occlusion rather than a pathological condition.

Adolescent↗

The craniofacial complex in cleft lip and palate: an update review of anatomy and function.

This report has been prepared for the purpose of updating the previous State-of-the-Art reports on the status of research on the anatomy and physiology of cleft lip and palate (Dickson, et al,. 1974, 1975; Maude-Dickson, 1977). It covers the literature from August, 1976 to August, 1978, on middle ear musculature, the auditory tube, the velopharyngeal mechanism, the lip, mandible, tongue, nose, and larynx. It also includes a review of the literature from August, 1972, through August, 1978, on the growth and development of the craniofacial skeleton. Significant advances have been made in our understanding of the velopharyngeal mechanism and auditory tube. Further investigation is needed on the innervation and blood supply to the velopharyngeal mechanism and on the effects of age, race, and sex on the development of the craniofacial skeleton in both normal and cleft-palate individuals. There is a continued need for interdisciplinary research.

Cleft Lip↗