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Long-term experiences with a computerized diabetes management and glucose monitoring system in insulin-dependent diabetic patients.

Only a minority of patients use diabetes management systems. In our study, 24 patients were given a memory based blood glucometer (ROMEO, Diva Medical Systems), which additionally allowed the input of insulin doses, food intake and exercise for up to four years. Eight patients returned ROMEO within one month (group I), 8 used the system as long it was available as a loan (group II) and 8 patients bought the system (group III). The patients of group III had a significantly better diabetic control (HbA1 = 7.8% +/- 0.7 (S.D.) vs. 11.7 +/- 3.6 (group I) and 10.7 +/- 2.6 (group II)) and were more reliable in their input of the data. After 3 years, however, only five patients of group III continued to use the system, but as a glucose meter only. One patient used the options of the system. These data show that glycemic control is not a question of the equipment. After a certain period, even the well-motivated patients do not use the system options routinely. Obviously, the advantages of the system are only used by a minority of patients characterized by good metabolic control and good compliance, and even these patients do not persistingly use all the options of the system after a certain period of time.

Adolescent↗

Wisconsin's violent death reporting system: monitoring and responding to Wisconsin's violent deaths.

In 2003, the Centers for Disease Control and Prevention (CDC) awarded the Wisconsin Department of Health and Family Services, Injury Prevention Program, a grant to participate in a multistate project called the National Violent Death Reporting System (NVDRS). The purpose of the Wisconsin Violent Death Reporting System (WVDRS) is to link violent death records (death certificates, police reports, medical examiner and coroner reports, crime laboratories, and perhaps child fatality review teams) from the same event, promote more timely information retrieval, describe in detail circumstances that may have contributed to the violent death, and identify and characterize perpetrators and their relationships to victims. This article describes the development of WVDRS and its importance in understanding and preventing violent injury and death in Wisconsin.

Accidents↗

Effects of elevated ICP on brain function: can the multiparametric monitoring system detect the 'Cushing Response'?

The 'Cushing Response' is a significant phenomenon associated with elevated ICP. The purpose of our study was to examine the effects of the intracranial hypertension level and duration on the cerebral tissue physiology, using a Multiprobe assembly (MPA). The parameters monitored simultaneously included ICP, CBF, mitochondrial NADH redox state, extracellular K+ and H+ levels, DC potential and ECoG, calculated CPP and blood pressure. Two groups of rats were used. In one group, ICP was elevated to 50-60 mmHg for 13-15 min and, in the second group, ICP was elevated to 20 mmHg for 30 min. The results show that ICP of 50-60 mmHg led to CPP reduction below the lower limits of autoregulation. However, ICP of 20 mmHg, even for a prolonged period of time is completely tolerated. Additionally, we found that the 'Cushing Response', developed in the moderate treatment (ICP = 20 mmHg) is beneficial, assuring high CBF levels under intracranial hypertension. Furthermore, CBF and CPP monitoring, apparently, are not sufficient for autoregulation assessment; more parameters are needed.

Animals↗

Intraoperative thermal artery imaging of an EC-IC bypass in beagles with infrared camera with detectable wave-length band of 7-14 microm: possibilities as novel blood flow monitoring system.

OBJECTIVE: In the past, the usefulness of thermal arterial imaging during coronary bypass surgery using an infrared camera has been reported by several investigators. The goal of this study is to apply this novel imaging system for intraoperative arterial imaging, as well as to develop new utilizations for a neurosurgical procedure. MATERIALS: We have attempted real-time imaging of anastomotic and flow status in an external carotid-internal carotid artery (EC-IC) bypass surgery using a new-generation infrared camera (IRIS IV thermographic imaging system) in beagles. No contrast medium or radiation was used to obtain the images. The detectable wave-length band of the infrared lens was 7-14 microm. After completion of bypass monitoring, an additional teflon tube was inserted into a branch of the STA to inject physiological saline of different temperatures to see the changes in cortical images. RESULTS: Anastomotic and flow status were clearly visualized throughout the operation without local surface cooling, which had been an inevitable procedure in coronary imaging to make a pronounced temperature difference between artery and adjacent tissue. In addition, cortical flow territory was visualized after injection of either cold or warm physiologic saline into the artery from an additionally inserted teflon tube into a branch of STA via bypass artery. CONCLUSION: From the present experience, it is considered that infrared imaging using a detectable wave length band of 7-14 microm may be applicable to a wide variety of near surface lesions, providing a non-invasive functional angiography.

Animals↗

A simple ethological monitoring system to assess social stress in group-housed laboratory rhesus macaques.

The increasing awareness of the importance of social housing of laboratory primates results in the establishment of group housing in many facilities. Our aim was to develop a set of manageable tools to allow continuous monitoring of social relations within groups and to establish an objective, scientific ground on which changes in group composition could be based. We studied 38 adult rhesus monkeys (Macaca mulatta) grouped as five one-male/multi-female groups using focal sampling. We recorded the occurrence and direction of aggressive and non-aggressive social interactions as well as time spent inactive in proportion to social contacts, feeding and other activities. The present analysis clearly identified low-ranking animals with none or few affiliative contacts and who also spent much time inactive and separated from other low-ranking animals. This suggests that the present approach results in useful information concerning compatibility between group members and enables identification of animals experiencing high social stress.

Aggression↗

Implementation of a monitoring system to measure impact of stormwater runoff infiltration.

Stormwater infiltration is a drainage mode, which is more and more used in urban areas in France. Given the characteristics of urban surfaces, and especially the loads of various pollutants contained in stormwater, it is important to assess the impact of stormwater infiltration systems on soil and groundwater by carrying out field experiments. The main difficulty is due to the complexity of the system observed and the need of multidisciplinary approaches. Another difficulty is that measurements are carried out in situ, in an uncontrolled environment submitted to quantitatively and qualitatively highly variable interferences. Very long term monitoring is needed to get representative results. In order to contribute to solve these problems, the OTHU project has recently been launched in Lyon (France). One of its key action concerns a long-term (10 years) experiment on an infiltration basin specifically rehabilitated for measurements and operational drainage issues. This paper presents the experimental site, the objectives of the project and the way the monitoring process has been built according to the various disciplines involved (biology, ecology, hydrology, chemistry and soil sciences) and to the will of assessing all the uncertainties in the measurement process.

Cities↗