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Pathological mechanism of idiopathic scoliosis: experimental scoliosis in pinealectomized rats.

The pathological mechanism of curve progression in idiopathic scoliosis is still obscure. In this study we investigated the pathological mechanism of idiopathic scoliosis in experimentally induced scoliosis in rats. A total 30 rats were divided into three groups: ten bipedal rats with a sham operation, which served as the control; ten quadrupedal rats with pinealectomy; and ten bipedal rats with pinealectomy. Scoliosis developed only in pinealectomized bipedal rats and not in pinealectomized quadrupedal rats. Cervicothoracic lordosis developed in bipedal rats with or without pinealectomy. These deformities of lordoscoliosis in pinealectomized bipedal rats were similar to human idiopathic scoliosis. Lordosis or lordotic tendency was sufficient to cause the spine to rotate to the side. Rotational instability of the spine with rotation of lordotic segment appears to produce a characteristic scoliotic deformity as a secondary phenomenon. Our findings suggest that lordosis may develop in bipedal rats, but pinealectomy is required for the development of lordoscoliosis. Balanced muscle tone controlled by the postural reflex is important to maintain normal posture with a straight spine in the bipedal condition. The disturbance of equilibrium and other postural mechanisms secondary to a deficiency of melatonin after pinealectomy may promote development of lordoscoliosis with vertebral rotation especially in the bipedal posture.

Animals↗

The psoas major muscle: a three-dimensional geometric study.

The purpose of this study was to use anatomical data obtained from cadavers, and geometrical scaling data obtained from MRI scans of living subjects, to assess the line of action and mechanical function of the psoas major muscle in three dimensions about each lumbar spine level. In addition, the line of action of the psoas major was documented as a function of lordosis. A total of seven cadavers were dissected from which fibre/tendon architecture was measured, while MRI scans were performed on 15 males to obtain centroid paths and area scales of the muscle over its length. In this way, the curving path of muscle line of action was accommodated together with force and moment predictions that recognized the presence of a tendon at lower lumbar levels (up to L3 in some subjects) significantly increasing the stress. Results confirm that the mechanics of the psoas cannot be adequately represented with a series of straight line vectors from vertebral origins to insertion. Moreover, the mechanical action of the psoas major does not change as a function of lumbar spine lordosis as the muscle path of action changes in accordance with changes in spine posture. Functionally, contrary to claims, the psoas cannot act as a 'derotator' of the spine, does not impose large shear forces on the spine in any posture except at L5-S1, and cannot have major affects to 'control lordosis'. It has the potential to stabilize the lumbar spine with compressive loading and with bilateral activation, to laterally flex it, and can create large anterior shear forces but only at L5-S1.

Adult↗

In utero and lactational exposure of male rats to 2,3,7,8-tetrachlorodibenzo-p-dioxin. 2. Effects on sexual behavior and the regulation of luteinizing hormone secretion in adulthood.

When administered to postpubescent male rats, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) decreases plasma androgen concentrations. If such an androgenic deficiency were produced prenatally and/or early postnatally it could impair sexual differentiation of the central nervous system (CNS) and thereby alter male reproductive function. To examine this possibility, sexually dimorphic functions were assessed in male rats born to dams given TCDD (0.064, 0.16, 0.40, and 1.0 micrograms/kg, po) or vehicle on Day 15 of gestation. Masculine sexual behavior was assessed at approximately 60, 75, and 115 days of age. When TCDD-exposed males were caged with receptive control females their mount, intromission, and ejaculation latencies were far longer than normal; these effects were dose-related and were statistically significant at maternal doses as low as 0.16, 0.064, and 0.16 micrograms TCDD/kg, respectively. The numbers of mounts and intromissions to ejaculation were slightly increased by TCDD, while copulatory rates [(mounts+intromissions)/min] were significantly decreased at the three highest maternal doses. Except for a modest increase at the higher doses, TCDD had little effect on the postejaculatory interval. Following assessment of their masculine sexual behavior, the males were castrated and 6 weeks later tested for feminine sexual behavior (lordosis). After being primed with estradiol benzoate and treated with progesterone, males displayed dose-related increases in lordosis quotient and lordosis intensity in response to being mounted by another male. These effects were statistically significant at maternal doses as low as 0.16 and 0.40 micrograms TCDD/kg, respectively. To determine if perinatal TCDD exposure alters the sexually dimorphic regulation of luteinizing hormone (LH) secretion, the LH secretory responsiveness of the hypothalamic/pituitary axis to ovarian steroids was assessed. In unexposed, gonadectomized female rats primed with estradiol benzoate, progesterone injection produced a surge in plasma LH concentrations, whereas in similarly treated control males, plasma LH concentrations were unaffected by progesterone. In castrated, estradiol benzoate-primed male rats that were perinatally exposed to TCDD, progesterone treatment produced dose-related increases in plasma LH concentrations that were statistically significant at the two highest maternal doses. We conclude that in utero and lactational exposure to small amounts of TCDD demasculinizes and feminizes male rats. These effects cannot be accounted for by TCDD-induced hypophagia, modest reductions in adult plasma androgen concentrations, possible nonspecific changes in motor activity, or possible reductions in penile sensitivity to sexual stimulation. The altered sexual behaviors and LH secretion were observed when nearly all TCDD had been excreted (as evidenced by uninduced hepatic ethoxyresorufin-O-deethylase activity).(ABSTRACT TRUNCATED AT 400 WORDS)

Age Factors↗

Conservative treatment of a patient with syringomyelia using chiropractic biophysics protocols.

OBJECTIVE: To present a case of a 41-year-old man with syringomyelia and intractable pain and the subsequent reduction of symptoms. CLINICAL FEATURES: This patient acquired a traumatically induced syrinx in his upper cervical spinal cord after he fell approximately 9 feet and landed on his head, upper back, and neck 9 years before presenting for care. He was diagnosed with a spinal cord cyst (syrinx), located at approximately C2 through C4 after magnetic resonance imaging. In 1995, the patient underwent occipitoatlantal decompression surgery, which improved his symptoms for a short time. INTERVENTION AND OUTCOMES: The patient was treated using Clinical Biomechanics of Posture protocol. The patient was seen 26 times over the course of 3 weeks. His scale for pain severity decreased 50% and other subjective complaints decreased. His posture improved based upon pretreatment and posttreatment lateral cervical radiographs, showing a change from a 10 degrees lordosis with midcervical kyphosis to a 30 degrees lordosis. One-year follow-up examination showed stable improvement in the cervical lordosis and pain intensity. CONCLUSION: This case represents a change in subjective and objective measurements after conservative chiropractic care. This case provides an example that structural rehabilitation may have a positive effect on symptoms of a patient with syringomyelia.

Accidental Falls↗

Spinal deformity following surgery for spinal cord tumors and tumorous lesions: analysis based on an assessment of the spinal functional curve.

The mechanism of spinal deformity after surgical removal of a cervical spinal cord tumor or tumorous lesions was studied in 36 patients, based on the spinal functional curve prepared from the intersectional angle. The postoperative spinal deformity depends on the surgical level and the type of operation. In the laminectomy group, kyphosis of the upper cervical spine and compensatory increased lordosis of the lower cervical spine were observed in the C2 laminectomy patients. Localized kyphosis of the spine at the cervicothoracic junction and compensatory increased lordosis of the upper cervical vertebrae were noted in the C7 laminectomy patients. In the laminoplasty group, spinal deformities were less frequently observed, and when present the deformity was limited to a slight increase of lordosis, even in patients who had the facetectomy. These facts demonstrate the preventive effect of the laminoplasty regarding postoperative spinal deformity. Laminoplasty with reconstruction of the erector spinal muscles and the nuchal ligament is recommended for patients with a spinal cord tumor or a tumorous lesion. The spinal functional curve was significant in studying the biomechanics of the vertebral column with the advantage that both alignment and mobility of the spine are simultaneously, respectively and precisely visualized.

Adolescent↗

[Experience with lateral electric surface stimulation in the treatment of progressive idiopathic scoliosis].

Due to incorrect use of nomenclature, scolioses are incorrectly classified in the paper by Altekruse and Heine. The angle measurement is inaccurate and does not correspond to Cobb's measuring method. The accuracy of the scientific statement and its value can be derived from this. The results of treatment obtained by Altekruse and Heine were improvement in or standstill of the scoliosis in 80% of the cases and progression in over 17%. This corresponds to the "Natural History of Scoliosis:" 5 to 25% of juvenile scolioses (age 3 to 10 years according to Drummont) are progressive, the figure for adolescent scolioses being lower. Therefore, electrostimulation is used to 70-80% in cases requiring no treatment, where there is no progression, in which there are no structural changes or which should be classified as malposture, in which spontaneous remission usually occurs or which remain stationary. In scolioses of over 25 degrees, with proven progression and structural changes, and possibly also with positive family history, electrostimulation fails. As in almost all papers published to date, Altekruse and Heine's paper disregards the behavior of the sagittal curvature of the spine under electrostimulation. We demonstrate in two cases that electrostimulation can have a considerable pathologic effect, causing lordosis. Since, on the basis of recently adopted opinions, there is reason to believe that there is a causal connection between lordosis and the pathogenesis of scoliosis, it must be assumed that in such cases electrostimulation incites or aggravates the development of scoliosis or is at least potentially capable of doing so. At any rate, in the two cases in which it was demonstrated that electrostimulation caused lordosis, the scoliosis was significantly aggravated, so that in these cases at least it must be assumed that the method has a health-damaging effect. Electrostimulation is a cost factor which does not seem justifiable today, with economy an obligation. The cost of using it in a mere 100 cases would be sufficient to pay for proper screening of all the children in one school year in the Federal Republic. Children who are really at risk could be given effective treatment. In Sweden, this has resulted in 60% of the scoliosis operations previously required in populations of the same size no longer being necessary.

Adolescent↗

Cervical curvature after laminoplasty for spondylotic myelopathy--involvement of yellow ligament, semispinalis cervicis muscle, and nuchal ligament.

To assess the consequences of cervical laminoplasty on postoperative lordosis, a retrospective radiographic analysis of 31 patients undergoing laminoplasty for spondylotic myelopathy was completed. Special attention was paid to lordotic changes occurring at each level over more than 2 years. Preoperative lordosis remained unchanged with the patients wearing a cervical orthosis 1 week postoperatively. However the lordosis subsequently demonstrated a significant decrease in 87% of patients over an average of 3.1 years. Lordotic alignment at C2-C3 and C6-C7 before surgery significantly decreased in 81% and 58% of patients 1 week postoperatively, and 84% and 81% at last follow up, respectively, while lordotic alignment at other levels pre- and postoperatively did not significantly change. Loss of lordotic alignment was largely attributed to detachment of semispinalis cervicis muscle on C2 and nuchal ligament on C6/C7 with a posterior approach and/or section of yellow ligament at C2-C3.

Adult↗

Posterior lumbar osteotomy for flat back in adults.

Several studies describe sagittal realignment for flat back and related kyphotic decompensation. Official guidelines for sagittal and the frontal realignment have not been developed. In this retrospective study, the authors examined 10 patients with flat back syndrome and treated a related kyphotic decompensation syndrome by posterior wedge osteotomy. The authors' goal was to determine the efficacy of one-level osteotomy on sagittal and frontal realignment. The effectiveness of osteotomy performed mainly in L3 or L4 was measured in terms of radiographic sagittal and frontal alignment. Sagittal unbalance was improved in all patients. The correction is related to the restitution of lumbar lordosis (5 degrees of lordosis allows 1 cm of sagittal correction). However, frontal balance is difficult to restore or even to maintain. In one patient, it was worsened and required repeated operation. One-level lumbar osteotomy is a safe procedure to correct sagittal unbalance. Peroperative lordosis correction allows reliable correction planning. The remaining problem is planning for frontal balance correction.

Female↗

Spinal deformity following selective dorsal rhizotomy.

The authors performed a review of 79 patients treated by selective dorsal rhizotomy with laminoplasty, 78 of whom were ambulatory, to determine the prevalence of spinal deformities. The mean radiographic follow-up was 4.2 years, the mean clinical follow-up 5.8 years. Scoliosis (11 degrees -24 degrees ) was identified in 13 children, none of whom had a preexisting deformity. There were no significant differences between preoperative and follow-up thoracic kyphosis or lumbar lordosis, although there was a significant difference in lumbar lordosis between sitting and standing radiographs. No progressive or rigid hyperlordotic deformities were observed in the lumbar spine. Spondylolisthesis was identified in nine children (12%) (8/9 grade I), and one patient required an arthrodesis for pain. Spondylolisthesis was correlated with greater lumbar lordosis, stronger hip abductors, and increased popliteal femoral angles preoperatively, and with stronger hip flexors postoperatively. Back pain was identified in 4 of the 79 patients at last follow-up, 2 of whom had spondylolisthesis. As some cases of spondylolisthesis will remain asymptomatic, periodic radiographic follow-up is recommended.

Cerebral Palsy↗

Pediatric cervical-spine immobilization: achieving neutral position?

This study was designed to evaluate prospectively the ability of current spine-immobilization devices to achieve radiographic-neutral positioning of the cervical spine in pediatric trauma patients. All trauma patients who required spinal immobilization and a lateral cervical spine radiograph were included in the study. A lateral cervical spine radiograph was obtained while the child was immobilized. The Cobb angle (C2-C6) was measured using a handheld goniometer. The method of immobilization, age at injury, and Cobb angle were compared. One hundred and eighteen patients with an average age of 7.9 years were enrolled. The majority were males (71%). The most frequent mechanisms of injury included motor vehicle accidents (35%) and falls (32%). The average Glascow Coma Scale score was 14. Although 31% of the children complained of neck pain, 92% were without neurologic deficits. The Cobb angles ranged from 27 degree kyphosis to 27 degree lordosis, and only 12 of the patients presented in a neutral position (0 degrees). Greater than 5 degrees of kyphosis or lordosis was observed in 60% of the children. Thirty-seven percent of the patients had 10 degrees or greater angulation. The most frequent methods of immobilization included a collar, backboard, and towels (40%), and a collar, backboard, and blocks (20%), but these techniques provided < 5 degrees kyphosis or lordosis in only 45% and 26% of the children respectively. No single method or combination of methods of immobilization consistently placed the children in the neutral position.(ABSTRACT TRUNCATED AT 250 WORDS)

Age Factors↗

Spinal sagittal configuration and mobility related to low-back pain in the female gymnast.

The purpose of this study was to correlate low-back complaints in 64 female gymnasts (mean age, 12 years) to spinal sagittal configuration and mobility as measured by two noninvasive methods. Measurements by Debrunner's kyphometer and Myrin's inclinometer were highly correlated. Average thoracic kyphosis was 32 degrees, lumbar lordosis 35 degrees. The mean range of sagittal motion was 57 degrees in the thoracic spine and 113 degrees in the lumbar spine. On average, 1 degree of the total sagittal lumbar mobility was lost for every 1 degree of increased lordosis. Low-back pain (LBP) was reported by 20% of the girls, and these girls had a significantly larger lordosis (41 degrees) than girls with no history of LBP (35 degrees).

Back Pain↗

Quantitation of three-dimensional deformity of idiopathic scoliosis.

Three-dimensional deformities in vertebrae of patients with idiopathic scoliosis were analyzed quantitatively using three-dimensional computed tomography. To evaluate the deformities, the vertebral lordosis and scoliosis were defined clearly. An average lordosis of 7.9 degrees and an average scoliosis of 6.8 degrees were calculated in 40 vertebrae near the top of the thoracic curve in 10 subjects with adolescent idiopathic scoliosis. Lordosis is characteristic of idiopathic scoliosis. Three-dimensional deformities in scoliotic patients cannot be represented precisely using the Cobb angle. A new technique for quantifying the three-dimensional deformities must be established.

Adolescent↗

Comparisons of lordotic cervical spine curvatures to a theoretical ideal model of the static sagittal cervical spine.

STUDY DESIGN: Measurements from lateral cervical radiographs of randomly selected patients are compared with two proposed ideal models. OBJECTIVES: To evaluate lordotic cervical curvatures from a large population base, to provide a geometric sagittal cervical spine model, and to test the validity of the model to predict measured angles and distances. Averages of ranges and normal values for cervical lordosis under conditions of static equilibrium are sought. SUMMARY OF BACKGROUND DATA: Seven angles and three distances were taken from 400 randomly selected lateral cervical radiographs of patients at a private clinic. METHODS: The radiographic measurements are compared with predicted values from our geometric sagittal cervical spine model and the Delmas ideal cervical model. RESULTS: Values were predicted successfully by the geometric model with an average error of 5% compared with the radiographic measurements. The range of lordosis, measured at the posterior of C2 and C7, was 16.5-66 degrees, with a mean of 34 degrees. The average height-to-length ratio for the cervical spine was 0.97. CONCLUSIONS: Predicted values from the geometric model were comparable with the measurements of the relative rotation angles at each vertebral interspace, absolute rotation angles from C2 to C7, and height-to-length ratios. A cervical lordosis of 34 degrees and a height-to-length ratio of 0.97 are suggested for clinical and theoretical outcomes.

Adult↗

The relationship between tight hamstrings and lumbar hypolordosis in children with cerebral palsy.

STUDY DESIGN: Retrospective clinical and radiographic review. OBJECTIVE: To assess the influence of tight hamstrings on the sagittal alignment of the thoracic and lumbar spine in children with cerebral palsy. SUMMARY OF BACKGROUND DATA: It is postulated that tight hamstrings may produce a hypolordosis of the lumbar spine. The abnormal sagittal contour of the spine may lead to increased stresses in the lumbar spine and subsequent pain and disability. This is of special concern in children with cerebral palsy who often have shortened spastic hamstring muscles. METHODS: Twenty-one patients were evaluated, with a mean age of 9.4 years. Standing and sitting lateral spine films were obtained and the lumbar lordosis and thoracic kyphosis were measured using the Cobb method. The popliteal angle was measured to assess hamstring tightness, such that a large popliteal angle indicates tight hamstrings. RESULTS: We found a statistically significant correlation between the sitting lumbar curve and popliteal angle (Pearson correlation value -0.77, P < 0.01). As the popliteal angle increased, the amount of lumbar lordosis decreased. This correlation was less significant when the patient was standing (Pearson correlation value -0.59). CONCLUSION: This study demonstrates that there is a correlation between tight hamstrings, as measured by the popliteal angle, and decreasing lumbar lordosis, especially when sitting.

Adolescent↗

Lumbar sagittal balance influences the clinical outcome after decompression and posterolateral spinal fusion for degenerative lumbar spondylolisthesis.

STUDY DESIGN: This study was designed to assess both lumbar sagittal balance and clinical outcomes of decompression and posterolateral fusion for degenerative lumbar spondylolisthesis. As an index for the radiologic evaluation of sagittal alignment, the L1 axis S1 distance was used (i.e., the horizontal distance from the plumbline of the center in the L1 to the back corner of the S1). OBJECTIVE: To determine whether lumbar sagittal balance affected the clinical outcome after posterolateral fusion. SUMMARY OF BACKGROUND DATA: Little is known about whether the sagittal vertical axis influences clinical outcomes in cases of degenerative lumbar spondylolisthesis. METHODS: A retrospective review of 47 patients (15 men and 32 women), ranging in age from 41 to 79 years, was conducted. The mean follow-up period was 3.6 years. Relations among outcomes including the visual analog pain scale, recovery rate, L1 axis S1 distance, slippage, and lumbar lordosis were evaluated. RESULTS: Recovery rates were 44% and 62% in patients whose preoperative L1 axis S1 distance, respectively, was more than 35 mm (Group A, n = 16) and less than 35 mm (Group B, n = 31) (P < 0.05). Follow-up assessment found a positive correlation between only lordosis and recovery rate. Severe low back pain and lower recovery rate were observed in patients with in situ fusion in Group A (n = 9), as compared with patients with reduced slippage in Group A (n = 7) and patients in Group B. CONCLUSIONS: Both preoperative L1 axis S1 distance and lordosis at follow-up assessment affected surgical outcome. Reduction of slippage may improve clinical outcomes of posterolateral fusion for degenerative lumbar spondylolisthesis with an L1 axis S1 distance more than 35 mm.

Adult↗

Functional outcome and radiographic correction after spinal osteotomy.

STUDY DESIGN: A prospective clinical trial to study the radiographic parameters and functional outcome in patients undergoing spinal osteotomy. OBJECTIVES: To determine whether correction of specific radiographic parameters is associated with improved functional outcome. SUMMARY OF BACKGROUND DATA: Although vertebral osteotomies have been shown to improve functional outcome in patients with spinal deformity, no prospective reports have studied whether correction of specific radiographic parameters is associated with improvement in functional outcome. METHODS: Eighty-three patients with fixed sagittal and/or coronal deformity were followed over a 7-year period. Patients were evaluated clinically and radiographically and completed a SF-36 Health Survey and American Academy of Orthopedic Surgeons Modems Instrument questionnaire. Spearman correlation analysis was used to determine the association between correction of radiographic parameters and functional outcome. RESULTS: Mean preoperative lumbar lordosis measured -14.2 degrees (i.e., kyphosis) with an average postoperative correction of 27.9 degrees. Mean preoperative lumbar scoliosis measured 40.1 degrees with an average postoperative correction of 15.1 degrees. Mean preoperative plumb sagittal and coronal plane alignment was 8.37 cm and 4.22 cm, respectively; after surgery they improved to 3.33 cm and 2.31 cm, respectively. A significant association was found between sagittal angular correction and physical function (P = 0.034) and role-physical (P = 0.01) when postoperative lumbar lordosis was >25 degrees. A significant association was also found between plumb coronal correction and physical function (P = 0.041), vitality (P = 0.05), and social function (P = 0.047) when postoperative plumb coronal alignment was <2.5 cm. CONCLUSIONS: Correction of sagittal and coronal deformity is important in the treatment of spinal deformity. A significant association was found between outcomes and radiographic correction of coronal and/or sagittal deformity if postoperative sagittal lordosis was >25 degrees and if postoperative plumb coronal alignment was <2.5 cm. Therefore, these radiographic parameters should be the goal of a spinal osteotomy. The surgery has a relatively high complication rate.

Adult↗

Circumferential lumbar spinal fusion with Brantigan cage versus posterolateral fusion with titanium Cotrel-Dubousset instrumentation: a prospective, randomized clinical study of 146 patients.

STUDY DESIGN: A prospective randomized clinical study with a 2-year follow-up period was conducted. OBJECTIVE: To analyze the effects of circumferential fusion using ALIF radiolucent carbon fiber cages and titanium posterior instrumentation on functional outcome, fusion rate, complications, and lumbar lordosis. SUMMARY OF BACKGROUND DATA: Circumferential fusion has become a common procedure in lumbar spine fusion, both as a primary and salvage procedure. However, the claimed advantages of ALIF plus PLF over conventional PLF lack scientific documentation. METHODS: From April 1996 through November 1999, a total of 148 patients with severe chronic low back pain were randomly selected for either posterolateral lumbar fusion with titanium CD-Horizon (posterolateral group) or circumferential fusion with a ALIF Brantigan cage plus posterior instrumentation. The Dallas Pain Questionnaire (DPQ), the Low Back Pain Rating Scale (LBPR), and a questionnaire concerning work status assessed their outcomes. RESULTS: Both groups showed highly significant improvement in all four categories of life quality (DPQ) as well as in the back pain and leg pain index (LBPR), as compared with preoperative status. There was a clear tendency toward better overall functional outcome for patients with the circumferential procedure ( < 0.08), and this patient group also showed significantly less leg pain at the 1-year follow-up evaluation ( < 0.03) and less peak back pain at 2 years ( < 0.04). Sagittal lordosis was restored and maintained in the circumferential group ( < 0.01). The circumferential fusion patients showed a higher posterolateral fusion rate (92%) than the posterolateral group (80%)( < 0.04). The repeat operation rate including implant removal was significantly lower in the circumferential group (7%) ( < 0.009) than in the posterolateral group (22%). CONCLUSIONS: Circumferential lumbar fusion restored lordosis, provided a higher union rate with significantly fewer repeat operations, showed a tendency toward better functional outcome, and resulted in less peak back pain and leg pain than instrumented posterolateral fusion. The clinical perspective of the current study implies a recommendation to favor circumferential fusion as a definitive surgical procedure in complex lumbar pathology involving major instability, flatback, and previous disc surgery in younger patients, as compared with posterolateral fusion with pedicle screws alone.

Adult↗

Sagittal profile of the elderly.

Little is known about the natural history of spinal alignment as it ages into the eighth and ninth decades. Fifty asymptomatic volunteers 70-85 years of age (mean 76 years) without any history of spine pain, trauma, or deformity were radiographed in the standing lateral position, from C7 to the pelvis including the hips. Measurements included segmental angulations, kyphosis, lordosis, and C7 plumb line balance. In addition, measurements of sagittal pelvic balance were made (pelvic incidence, tilting, sacral slope, and S1 overhang). Average kyphosis was 52 degrees (range 29 degrees to 79 degrees); the average lordosis was -57 degrees (range -96 degrees to -20 degrees). The C7 plumb line on average fell 40 mm anterior to the posterosuperior corner of S1. The anterior positioning of C7 was also positively correlated with age and decreasing lordosis. This provides further data into the natural history of the aging spine.

Aged↗