[Duodenal stenosis in the new-born infant. (Study of 98 cases)].
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The cases of two infants with prenatally diagnosed cystic meconium peritonitis, who underwent minimal surgical procedure (drainage) first and elective surgery later, are reported. Just after birth tube drains were inserted under local anesthesia with ultrasonographic guidance. They underwent laparotomy, at 16 days in case 1 and at 20 days in case 2. The adhesions were quite easily dissected, ileal atresia was found, and the intestines were safely primarily anastomosed. In cystic meconium peritonitis, radical surgery in the early neonatal period is usually difficult, so many patients require second or third operations. We recommend cyst drainage just after birth and elective surgery later.
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Fetal bowel obstruction has a prevalence of 1 in 3000 to 5000 live births. Ultrasonographic diagnosis is made by demonstrating distended loops of bowel. Echogenic bowel, defined as small bowel more echogenic than liver or bone, has been associated with congenital infections, cystic fibrosis, chromosomal abnormalities, and bowel obstruction. Fetal ascites, defined as fluid in the peritoneal cavity partly surrounding the liver and bladder, also has been associated with bowel obstruction. We present a case of jejunal atresia whose presenting appearance consists of echogenic bowel, transient ascites, and massive dilatation of intestinal loops.
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A wide range of abnormalities of the fetal gastrointestinal tract is currently detectable by antenatal sonography, but the sonographic appearance of normal fetal bowel is variable, with considerable overlap between normal and abnormal patterns. In examining the major gastrointestinal disorders that may be recognized by in utero sonography, this article emphasizes potential pitfalls due to confusion with normal anatomic variants and pathologic processes arising elsewhere in the fetus.
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The treatment of long gap oesophageal atresia is still a problem. In a self-developed method oesophageal defects were repaired by interposition of free jejunal mucosal/submucosal transplants. Two children, in whom long gap oesophageal-atresia was surgically repaired by inserting such transplants of 5 cm each, subsequently showed total histological healing, environmental adaptation with a surrounding fibrous scar. Functionally, there was free oesophageal passage to food. The children died of associated congenital anomalies three versus 12 months postoperatively. The advantages of this method are being emphasized.
Jejunoileal atresia without significant shortening of total intestinal length, was created in five date-bred Dorset ewes by devascularizing a 15 cm segment of fetal intestine at 90-100 days gestation. Light microscopy showed mucosal hypertrophy distal to the atresia with almost total obliteration of the lumen by tail, feathery-shaped villi similar to those observed in newborns with jejunal atresia. Scanning electron microscopic views of the proximal mucosa showed the villi to be thicker, more segmented and tended to congregate compared to normal villi and those distal to the atresia. No evidence of microvillus, intracellular or capillary membrane change or injury could be identified to explain the functional secretory state.
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