The hunger artists.
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A tracer kinetic study with [14C]-1-palmitic acid was carried out to study the influence of acute exposure to cold and starvation on free fatty acid (FFA) metabolism in serum of newborn rabbits. The turnover rate of serum FFA was 10.20 mumol/min in well fed rabbits kept in a thermoneutral environment (normal conditions). Cold exposure as well as starvation either in a cold or thermoneutral environment resulted in a diminution of the turnover rate, being the consequence of a significantly reduced pool of FFA. It was 9.57 mumol under normal conditions. The disappearance rate (1.07 min-1), half time (0.65 min) and turnover time (0.94 min) of well nourished animals was slightly, but mostly not significantly, influenced by cold exposure and starvation. The cold induced increase in serum FFA concentration and the decrease following restoration of thermoneutrality did not run parallel with changes in the absolute turnover rate.
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