Search PubMed⌕ Search

SEARCH · Search PubMed

Results for “HAWAII”

Search indexed PubMed citations on genomics, clinical trials, systematic reviews and public health. Explore titles, authors and supplied subject terms, then open the PubMed record.

Quote a phrase for an exact phrase match. Source license links do not imply unrestricted reuse.

At least 883 records · Page 49Linked to original sources
PubMed2005

Helicobacter pylori, pepsinogen, and gastric adenocarcinoma in Hawaii.

BACKGROUND: The objective was to investigate the association of Helicobacter pylori and serum pepsinogen (PG) levels with gastric adenocarcinoma. METHODS: Serum obtained from 299 patients at the time of cancer diagnosis and from 336 population-based control subjects was tested for PG I, PG II, and antibodies to H. pylori and to CagA. RESULTS: Subjects with low PG I levels or low PG I/II ratios were at increased risk for cardia and noncardia gastric cancer, whereas those with H. pylori or CagA seropositivity had an elevated risk for noncardia cancer only. Subjects seropositive for either H. pylori or CagA who had low PG I levels had the highest odds ratio (OR) (9.21 [95% confidence interval {CI}, 4.95-17.13]) for noncardia cancer, compared with subjects with neither factor. Elevated risks were also found among subjects with only 1 factor (OR, 5.40 [95% CI, 2.61-11.20] for low PG I level only; OR, 4.86 [95% CI, 5.90-8.13] for H. pylori or CagA seropositivity only). This pattern persisted when PG I/II ratio replaced PG I level and when CagA seropositivity alone replaced H. pylori immunoglobulin G or CagA seropositivity. CONCLUSIONS: The results suggest that persons with both H. pylori or CagA seropositivity and a low PG I level or PG I/II ratio are highly susceptible to development of noncardia gastric cancer.

Adenocarcinoma↗
PubMed2004

Patterns of chromosomal translocations identified by a birth defects registry, Hawaii, 1986-2000.

Using a birth defects registry, this investigation examined the distribution of translocations by type of translocation, chromosomes involved in the translocation, pregnancy outcome, method of diagnosis, inheritance, and diagnosis of major structural birth defects. A total of 121 cases were identified through a statewide population-based birth defects registry. The translocations were reciprocal in 89 (73.6%) cases, Robertsonian in 32 (26.4%) cases, balanced in 86 (71.1%) cases, and unbalanced in 35 (28.9%) cases. Live births accounted for 76 (88.4%) of balanced translocations and 22 (62.9%) of unbalanced translocations. Diagnosis was made by amniocentesis or chorionic villus sampling in 72 (83.7%) of balanced translocations and 11 (31.4%) of unbalanced translocations. Of cases of known inheritance, the translocation was of maternal origin in 38 (46.3%) cases, paternal origin in 25 (30.5%) cases, and de novo in 19 (23.2%) cases. Major structural birth defects were diagnosed in 17 (19.8%) of balanced translocations and 20 (57.1%) of unbalanced translocations. Translocations were more likely to be reciprocal, balanced, and of maternal origin. Infants and fetuses with unbalanced translocations were less likely to be live births and diagnosed by amniocentesis or chorionic villus sampling and more likely to be diagnosed with major structural birth defects.

Amniocentesis↗
PubMed1977

Assessing the anthropometric status of Hawaii's preschoolers participating in feeding programs in day care centers.

A survey of low and middle income preschoolers who were exposed to similar feeding programs and physical activities showed similarity of physical growth between the two groups of children. Mean values of arm size, muscularity, triceps skinfold, and fat area were similar and signified adequate protein status and caloric reserves in both groups of children. Comparison of data from preschoolers in Oahu and on the United States mainland showed that all left arm triceps skinfold medians of preschoolers in Oahu were 1) smaller than the medians recorded for right arms in the Health and Nutrition Examination Survey and 2) greater than the values on the 50th percentile for right arms of white children of the Ten-State Nutrition Survey, which indicated that Oahu preschoolers occupied a caloric reserve intermediate between the two mainland United States populations surveyed. Medians of heights and weights were lower than the median values of the Health and Nutrition Examination Survey and were closer to the 50th percentile of while children in the Ten-State Nutrition Survey.

Anthropometry↗
PubMed1978

Breast cancer and diet among the Japanese in Hawaii.

Eighty-six Japanese men out of 6860 male participants in a prospective study of cancer were married to women who had breast cancer. These 86 men were compared with the remaining men by dietary factors that were identified during two different time periods. Based on the assumption that there is a similarity between husbands and wives in their dietary patterns, it was noted that the spouses of women with breast cancer consumed more beef or meat, butter/margarine/cheese, corn, and wieners than the other men. Furthermore, the breast cancer spouses also consumed less Japanese foods than controls, even though there were minimal differences between the two groups in other Oriental practices. These results suggest that certain American foods are important in the search for possible dietary factors related to the occurrence of breast cancer in women.

Adolescent↗
PubMed1984

Dietary cholesterol and lung cancer risk among Japanese men in Hawaii.

Dietary cholesterol intake was estimated for 7539 men clinically examined from 1965 to 1968, as part of a prospective cohort study. After 15 yr of surveillance, 113 incidence cases of lung cancer have been identified. We found no significant association between dietary cholesterol intake and lung cancer risk, either before or after adjustment for age and pack-years of cigarette smoking. Cases under age 60 at examination did consume more dietary cholesterol than controls of the same age group, but no significant age/dietary cholesterol interaction effect could be found. No significant association could be found with any of the subgroups of cases defined by: clinical stage of disease, histological type, or time interval from examination to diagnosis.

Age Factors↗