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PubMed2000

Pharyngeal pressure analysis by the finite element method during liquid bolus swallow.

The human pharynx is unique, acting as a complex interchange between the oral cavity and the esophagus, and between the nasal cavity and the lungs. It is actively involved in the transport of food and liquid, producing the forces that guide the bolus into the upper esophagus and away from the adjacent larynx and lungs. This study developed a biomechanical computer model of the human pharynx, utilizing a finite element method (FEM). Control 2-dimensional cine computed tomography images were obtained during 10-mL barium paste swallows at 8 levels extending from the tongue base to the cricopharyngeal level in order to encompass the entire pharynx. Three-dimensional finite element models of the pharynx were reconstructed from the geometric information obtained from the images at each level. Using an inverse dynamic approach with the addition of known tissue properties, we analyzed the 8 models under estimated pressure histories during swallow. Within each model, changes in the cross-sectional intraluminal area were calculated and compared with the area from the computer-generated FEM model. Area matching allowed estimation of intraluminal pressure gradients during swallow. The estimated pressure gradients were distributed through a range from 10 to 55 mm Hg, varying from one region to another and showing different patterns for the upper 4 levels and the lower 4 levels. The contraction velocity for the upper 4 levels was much higher than that for the lower 4 levels. The higher contraction velocities and pressure gradients in the upper levels are consistent with the bolus velocities required for efficient swallow.

Biomechanical Phenomena↗
PubMed2006

M/F ratios of four different closing loops: 3D analysis using the finite element method (FEM).

BACKGROUND: It has been claimed that the opus loop is capable of delivering a constant and optimum M/F ratio without the need for gable bends. OBJECTIVE: To compare the forces, moments and moment/force (M/F) ratios of the opus loop, L-loop, T-loop and vertical helical closing loop (VHC loop) in a segmented arch with the finite element method (FEM). METHODS: The FEM was used to compare 3D models of closing loops in rectangular (0.016 x 0.022 inch) stainless steel wire. The L-, T- and VHC loops were designed with and without preactivation bends. The opus loop had no preactivation bends. The T-Loops were 10 mm in height and 10 mm in length. The horizontal and vertical forces, the moments and the M/F ratios at the alpha and beta ends were recorded at 0, 0. 1, 0.4, 0.7 and 1 mm intervals. RESULTS: The highest horizontal and vertical forces were produced by the L-loop (with and without preactivation bends) and in most cases the lowest forces were produced by the VHC loop. Loops with preactivation bends produced marked changes in the M/F ratio and loops without preactivation bends low, but relatively constant, M/F ratios over the full range of activation. Of the loops modelled without preactivation bends the opus and T-loop had the highest M/F ratios (7.20 - 7.67 mm at the anterior ends). CONCLUSION: Stainless steel opus and T-loops without preactivation bends had constant M/F ratios, but both loops failed to deliver the optimum M/F ratio of 10:1.

Biomechanical Phenomena↗
PubMed1993

[3-dimensional finite element stress analysis of the periodontal ligament of bridge abutments in mandibular posterior fixed bridge].

According to the measured data, the characters of all components of fixed bridge and the periodontal supporting tissues, and the dividing principals of finite element, the three-dimensional finite element model was developed on the basis of a try adult mandible. 6 vertical loadings and 1 horizontal loading were applied on the abutments and the pontic. The Emax and Emin of PDL were calculated and the resulting principal stresses were plotted for each loading.

Adult↗
PubMed2005

Mechanical behavior and quantitative morphology of the equine laminar junction.

The horse's hoof is structurally modified for its mechanical functions, but studying the functional design of internal structures is hampered by the external keratinous capsule. Finite-element analysis offers one method for evaluating mechanical function of components within the capsule, such as the laminar junction. This is the epidermodermal connection that binds the hoof wall strongly to the distal phalanx. Primary epidermal laminae (PEL), projecting inward from the wall, vary in morphology and are remodeled despite being keratinous. The aim of this study is to investigate the suggestion that remodeling of PEL is influenced by mechanical stress. Circumferential and proximodistal stress distribution and relative displacement in the laminar junction are assessed by finite-element analysis (FEA) of nine hoof models. Spacing, orientation, and curvature of PEL are assessed from sections through 47 other hooves and compared with the stress and displacement data. Significant correlations are found between laminar spacing and seven displacement and stress variables, supporting the link between stresses and remodeling. Differences in external hoof shape cause regional variation in stress magnitudes around the laminar junction. This finding is in accord with previous observations that laminar morphology is individually regionally variable. This work provides the first concrete link between mechanical behavior and laminar morphology.

Animals↗
PubMed1997

[Bad clinical results of cemented caps with metal-backed acetabular components. 124 cases with 21 months follow-up].

PURPOSE OF THE STUDY: The authors reviewed with short term follow-up 124 total hip arthroplasties using a cemented metal-backed acetabular component. The purpose of the study was to evaluate clinical and radiological results because of early periacetabular radiolucent lines reported by Ritter. MATERIAL AND METHODS: Surgical procedures were performed in 1988 and 1989 with Saint-Antoine prosthesis (PSA) including cemented titanium metal-backed socket. Functional results were appreciated with Postel-Merle d'Aubigne's score. Radiological results were appreciated using De Lee and Charnley's criterias for radiolucent lines and Yoder's criterias for socket's migrations. We studied correlation between radiolucent line and age, weight, hip disease, associated bone graft, socket size and technical errors. RESULTS: With short term follow-up (21 months), we found 60.4 per cent hips with a maximal PMA score (18) with an average score of 17.5 per cent. We observed 26.4 per cent of complete periacetabular radiolucent lines with 3 sockets loosening with migration. No significant correlation were found between radiolucent lines and age, weight, hip disease, associated bone graft, socket size, and technical errors. DISCUSSION: This periacetabular radiolucent line rate was comparable to the results of the series using such a cemented metal-backed socket. This rate was clearly higher than the results of others series using cemented polyethylene sockets. These bad results were not correlated to those of finite elements analysis. We think that this is due to metal-backed socket excessive rigidity. CONCLUSION: Because of this high periacetabular radiolucent line rate, despite of finite elements analysis results, we no more use cemented metal-backed acetabular socket since 1991.

Adult↗
PubMed1998

Composite hip prosthesis design. I. Analysis.

An investigation was performed to study the mechanical performance of fiber-reinforced composite hip prostheses in a femur. The main objective of the study was to evaluate the effect of fiber orientation of a composite femoral implant on the response of the surrounding femoral bone. A three-dimensional finite element analysis was developed for analyzing a composite implant in the femur. A three-dimensional composite element was proposed to take into account ply drop-off due to a change of cross-section of the composite implant. The element could accommodate multidirectional layers and tapered composites. The material properties of the composite were treated as anisotropic and inhomogeneous while the properties of femoral bone were treated as anisotropic and homogenous. All the materials were assumed to behave linear-elastically. The thermoplastic graphite/PEEK material system was selected for the study. In this presentation, as the first part of the study, the development of the finite element analysis will be described. Numerical calculations were generated and compared with existing data and numerical results available from studies related to metal hip prostheses in the literature. Experiments on the composite hip implants were also conducted for further verification of the analysis and the computer simulations. In Part II, using the finite element code, an extensive study was performed to evaluate the stress/strain distributions, micromotions, and strain-energy density of the surrounding femoral bone, which have been related to initial fixation and long-term stability of the prosthesis in a femoral bone. Numerous fiber orientations were studied, and results of the calculations were compared with those generated by the prosthesis made of cobalt alloy and titanium alloy.

Hip Prosthesis↗
PubMed1989

A retrospective cephalometric study of Class I patients.

In view of the growing consensus that traditional cephalometric analyses yield data of dubious scientific validity, this study was undertaken using an alternative technique, termed finite element analysis (FEA). The study was based on 14 triangular finite elements spanning seven datum (nodal) points delineating cephalometric form. These points were delineated on lateral cephalographs taken immediately before and following the completion of orthodontic treatment for two samples of boys aged 12-16 years. Although both samples exhibited Class I molar occlusions with anterior over-crowding, one sample required bilateral maxillary and mandibular first premolar extraction prior to orthodontic treatment, while the other sample did not. FEA revealed greater cephalometric size and shape changes in the 'non-extraction' than 'extraction' samples. Such sample contrasts, however, varied depending upon the finite element included in the analysis. Further studies are therefore required to delineate the specific finite element configurations to provide precise descriptions of cephalometric change.

Adolescent↗
PubMed2002

High-resolution MRI and micro-FE for the evaluation of changes in bone mechanical properties during longitudinal clinical trials: application to calcaneal bone in postmenopausal women after one year of idoxifene treatment.

OBJECTIVE: To investigate whether recently developed in vivo high-resolution magnetic resonance-imaging and micro-finite element techniques can monitor changes in bone mechanical properties during long-term clinical trials aiming at evaluating the efficacy of new drugs for the treatment of osteoporosis. DESIGN: Comparison of baseline and follow-up mechanical parameters calculated using micro-finite element analysis of the calcaneus for subjects participating in a study investigating the effect of idoxifene. BACKGROUND: Contemporary measurements for the evaluation of bone mechanical properties, based on dual-energy X-ray absorptiometry measurements, are not very accurate and require large trial populations. METHODS: A total of 56 postmenopausal subjects received either a placebo, 5 mg or 10 mg per day of idoxifene. Magnetic resonance-images of the calcaneus were made at baseline and after one year. Mechanical parameters of a trabecular volume of interest in the calcaneus were calculated using micro-finite element analysis. RESULTS: Although there were no significant differences between the mean changes in the treated groups and the placebo group, there were significant changes from baseline within groups after one year of treatment. Significant changes, however, were found only for mechanical parameters and only in the treated groups. CONCLUSIONS: The present study is the first demonstration that longitudinal changes in bone mechanical properties due to trabecular micro-architectural changes may be quantified in long-term clinical studies. Since significant changes in mechanical parameters were obtained for the treated groups whereas no significant change in bone mass was found we conclude that the application of these techniques may increase the clinical significance of these trials. RELEVANCE: A precise diagnosis of in vivo bone mechanical properties that accounts for (changes in) trabecular bone architecture is of particular importance for longitudinal clinical trials aiming at evaluating the efficacy of new drugs since it can lead to clinically relevant results from shorter follow-up intervals and may enable a reduction of the number of patients involved in the trial.

Bone Density↗
PubMed2006

Transformation of hydrogel-based inverse opal photonic sensors from FCC to L1(1) during swelling.

The structural evolution of Bragg diffracting inverse opal hydrogel sensors during swelling is directly observed by two-photon laser scanning fluorescence microscopy and compared to predictions from finite element analysis. A fluorescently labeled pH-sensitive hydrogel is UV-polymerized in a dried polystyrene colloidal crystal template, which is etched to yield an inverse opal. Fluorescence imaging of the hydrogel at different pH values reveals an inhomogeneous deformation of the FCC array of aqueous pores. The pores elongate along the sample normal direction and collapse along the sample parallel directions, consistent with the Bragg response, which indicates a 1-D increase in the interlayer distance. Interconnects between the pores serve as anchor points during hydrogel expansion into the pores. Pinning of the hydrogel to the substrate causes a change of the hydrogel lattice symmetry during deformation, from FCC (ABC stacking) to L1(1) (ABCA'B'C' stacking). Reconstructed cross-sections confirm that a 1-D increase in the interlayer distance along the substrate normal direction is responsible for the diffraction response of an inverse opal hydrogel sensor. Comparison with predictions from finite element analysis shows qualitative agreement, although the experimental mesostructure is significantly more deformed than the calculated data, due to buckling in the experimental system that is not captured by the model.

Biosensing Techniques↗
PubMed2006

Refractive change induced by the LASIK flap in a biomechanical finite element model.

PURPOSE: To study the effect of varying four parameters on the refractive change induced by the LASIK flap. METHODS: Using a variety of patient-specific data such as topography, pachymetry, and axial length, a finite element model is built. The model is used in a non-linear finite element analysis to determine the response and change in optical power of the cornea as a function of a material property of the cornea (corneal elasticity), flap diameter and thickness, and intraocular pressure. RESULTS: The central flattening or hyperopic shift occurred atop the flap in all four of the simulated eyes tested with the creation of the LASIK flap. Of the four parameters tested, modulus of elasticity (Young's modulus) had the most profound effect on the results of hyperopic shift, varying from <0.5 diopters (D) in the least elastic (stiffest) cornea to >2.0 D of hyperopic shift in the most elastic cornea. The depth of the lenticular cut was the second-most significant parameter tested varying from 0.24 D at 100 microns to 1.25 D at 275 microns of depth. Varying intraocular pressure demonstrated less difference, and varying corneal flap diameter demonstrated the least difference in induced refractive change on the model. The hyperopic shift was noted to be greater in hyperopic than in myopic eyes (simulated) tested. CONCLUSIONS: Three-dimensional finite element analysis modeling of actual patient data could lead to a better understanding of the biomechanical response of corneal tissue to the lenticular flap creation and potentially for ablation patterns produced by the excimer laser. Understanding these biomechanical responses may lead to greater predictability and improvement of visual outcomes.

Cornea↗
PubMed1995

Is stem length important in uncemented endoprostheses?

In an uncemented total hip replacement where the femoral stem is thinner than the medullary canal it may be hypothesized that the distal portion of the stem has no mechanical function. In this study an uncemented total hip replacement has been modelled mathematically using finite element analysis and mechanical tests of a similar system have been carried out loading implants in cadaveric proximal femora. Two implants have been tested mechanically; one with a full length stem and the second with the stem shortened, but three implants have been modelled with an additional intermediate length stem analysed. Additionally the finite element analysis has been done with a high neck resection and a standard level resection. The finite element model showed that the full length stem produced lower interface contact stress levels under the proximal neck, particularly when the nec was resected, and this was borne out by the mechanical testing.

Biomechanical Phenomena↗
PubMed2000

Stability analysis and finite element simulation of bone remodeling model.

Bone remodeling is widely viewed as a dynamic process--maintaining bone structure through a balance between the opposed activities of osteoblast and osteoclast cells--in which the stability problem is often pointed out. By an analytical approach, we present a bone remodeling model applied to n unit-elements in order to analyze the stationary states and the condition of their stability. In addition, this theory has been simulated in a computer model using the Finite Element Method (FEM) to show a relationship between the bone remodeling process and the stability analysis.

Bone Remodeling↗
PubMed1989

[Finite element stress analysis of ceramics crown on premolar. Relation between ceramics materials and abutment materials].

This investigation was carried out to evaluate the alteration of stress distribution on ceramics crowns by each combination of ceramics crown materials and abutment materials. Analyzing the stress distribution by the finite element methods, a two-dimensional model of jacket crown preparation was designed on lower first premolar, and restored it by ceramics crown. Under four loading conditions, the tensile stress distributions on the ceramics crown were analyzed to evaluate the relations between three kinds of ceramics crown, which were an aluminous porcelain jacket crown, a feldspathic porcelain jacket crown and an Olympus castable ceramics (O.C.C.) crown, and three kinds of abutment which were a natural tooth, a gold cast core and a composite resin core. And following results were obtained: 1. When the abutment was a natural tooth, the tensile stresses were apt to occur all over the ceramics crown and these magnitude were increased in porportion to the height of Young's modulus of the ceramics materials. 2. When the abutment was a gold cast core or a composite resin core, the tensile stresses were produced only at the loading side of the ceramics crown, and the magnitude of stress were little affected by the type of core materials.

Composite Resins↗
PubMed2005

Anchorage effect of various shape palatal osseointegrated implants: a finite element study.

The purpose of this study was to compare the anchorage effects of different palatal osseointegrated implants using a finite element analysis. Three types of cylinder implants (simple implant, step implant, screw implant) were investigated. Three finite element models were constructed. Each consisted of two maxillary second premolars, their associated periodontal ligament (PDL) and alveolar bones, palatal bone, palatal implant, and a transpalatal arch. Another model without an implant was used for comparison. The horizontal force (mesial 5N, palatal 1N) was loaded at the buccal bracket of each second premolar, and the stress in the PDL, implant, and implant surrounding bone was calculated. The results showed that the palatal implant could significantly reduce von Mises stress in the PDL (maximum von Mises stress was reduced 24.3-27.7%). The von Mises stress magnitude in the PDL was almost same in the three models with implants. The stress in the implant surrounding bone was very low. These results suggested that the implant is a useful tool for increasing anchorage. Adding a step is useful to lower the stress in the implant and surrounding bone, but adding a screw to a cylinder implant had little advantage in increasing the anchorage effect.

Bicuspid↗
PubMed2003

Biomechanical testing of the LCP--how can stability in locked internal fixators be controlled?

New plating techniques, such as non-contact plates, have been introduced in acknowledgment of the importance of biological factors in internal fixation. Knowledge of the fixation stability provided by these new plates is very limited and clarification is still necessary to determine how the mechanical stability, e.g. fracture motion, and the risk of implant failure can best be controlled. The results of a study based on in vitro experiments with composite bone cylinders and finite element analysis using the Locking Compression Plate (LCP) for diaphyseal fractures are presented and recommendations for clinical practice are given. Several factors were shown to influence stability both in compression and torsion. Axial stiffness and torsional rigidity was mainly influenced by the working length, e.g. the distance of the first screw to the fracture site. By omitting one screw hole on either side of the fracture, the construct became almost twice as flexible in both compression and torsion. The number of screws also significantly affected the stability, however, more than three screws per fragment did little to increase axial stiffness; nor did four screws increase torsional rigidity. The position of the third screw in the fragment significantly affected axial stiffness, but not torsional rigidity. The closer an additional screw is positioned towards the fracture gap, the stiffer the construct becomes under compression. The rigidity under torsional load was determined by the number of screws only. Another factor affecting construct stability was the distance of the plate to the bone. Increasing this distance resulted in decreased construct stability. Finally, a shorter plate with an equal number of screws caused a reduction in axial stiffness but not in torsional rigidity. Static compression tests showed that increasing the working length, e.g. omitting the screws immediately adjacent to the fracture on both sides, significantly diminished the load causing plastic deformation of the plate. If bone contact was not present at the fracture site due to comminution, a greater working length also led to earlier failure in dynamic loading tests. For simple fractures with a small fracture gap and bone contact under dynamic load, the number of cycles until failure was greater than one million for all tested constructs. Plate failures invariably occurred through the DCP hole where the highest von Mises stresses were found in the finite element analysis (FEA). This stress was reduced in constructions with bone contact by increasing the bridging length. On the other hand, additional screws increased the implant stress since higher loads were needed to achieve bone contact. Based on the present results, the following clinical recommendations can be made for the locked internal fixator in bridging technique as part of a minimally invasive percutaneous osteosynthesis (MIPO): for fractures of the lower extremity, two or three screws on either side of the fracture should be sufficient. For fractures of the humerus or forearm, three to four screws on either side should be used as rotational forces predominate in these bones. In simple fractures with a small interfragmentary gap, one or two holes should be omitted on each side of the fracture to initiate spontaneous fracture healing, including the generation of callus formations. In fractures with a large fracture gap such as comminuted fractures, we advise placement of the innermost screws as close as practicable to the fracture. Furthermore, the distance between the plate and the bone ought to be kept small and long plates should be used to provide sufficient axial stiffness.

Biomechanical Phenomena↗
PubMed2000

An axial skeleton based surface deformation algorithm for patient specific anatomic modeling.

Traditionally, finite element analysis or mass-spring systems are used to calculate deformations of geometric surfaces. Patient-specific geometric models can be comprised of tens of thousands, even hundreds of thousands of polygons, making finite element analysis and mass-spring systems computationally demanding. Simulations using deformable patient specific models at real time rates are prohibitive under such a computational burden. This paper presents a method for simulating deformable surfaces by deforming a skeletal representation of the surface, rather than the surface itself, yielding an efficient method for interactive simulation with models.

Algorithms↗
PubMed2002

Parallel computing in microwave heating analysis.

The use of parallel computing in the finite element analysis of microwave heating applicators is discussed. Numerical results for a multiple feed cavity at 896 MHz and a cavity with a mode stirrer at 2.45 GHz are presented, and it is shown that for the two structures parallelism is most effectively introduced at different levels in the analysis.

Algorithms↗