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A rare dermatoglyphic finger pattern in a Canadian kindred.

A Canadian three generation pedigree is presented where a woman has a rare radial loop plus radial loop pattern on the second digit of her left hand and her son has the same rare configuration on the same digit. We hope that this pedigree will encourage others to search for pattern configurations beyond the conventional arch-loop-whorl divisions.

Canada↗

[Dermatoglyphic changes in human genetic disorders: preaxial defects of the upper limbs].

Dermatologlyphic prints of 9 patients with preaxial (radial) hand defects were compared with control ones. A correspondence is revealed between a decrease in thumb phalanx length and a respective decrease in ridge count, on the one hand, and between the 1st metacarpal hypo- or aplasia and a decrease in palmar ridge count between the metacarpo-phalangeal and thumb flexion creases, on the other hand. An interrelation is found between the anomalies in flexion crease and respective joint formation. It is suggested, that these disorders are due to genetically determined anomalies in morphogenetic gradients which control the distribution of positional information in upper limb morphogenetic field.

Dermatoglyphics↗

Dermatoglyphics in leprosy: (III) Creases of palm.

Palmar configurations of triradii and creases of 100 leprosy patients [50 lepromatous (BL/LL) and 50 tuberculoid (BT/LL)] were compared with those of 100 normal persons selected from families of these patients. The patterns of position of triradii were similar in controls and leprosy patients as such. But, the patterns in the two types of leprosy patients were different. As for palmar creases patterns, there was significant difference between those of controls and patients, double radial base crease occurring more often in patients. However, the differences between the two types of patients were not statistically significant.

Dermatoglyphics↗

[Dermatoglyphic studies in parents of children with Down's syndrome. I. Digital patterns].

Finger prints of 34 groups of parents with a child affected of Down's syndrome by regular trisomy were studied and then compared with 34 groups of parents with two or more normal children without family antecedents of genetic alterations. The separate study of the distribution of the pattern types in each of the fingers and the latter comparison of the two groups shows: Different distribution of the pattern types in the two groups. The groups of parents of children affected of Down's syndrome occupies an intermediate position between the group of parents of normal children and a group of subjects affected of Down's syndrome. The total sum of pattern types in each group were also compared using a table of contingency, indicating a difference (SD p less than 0.05) between both groups.

Adult↗

Dermatoglyphic patterns in senile dementia of Alzheimer's type.

Several reports suggest a genetic relationship between senile dementia of Alzheimer type (SDAT) and Down's syndrome. We have analyzed fingerprints and palmar patterns in an elderly female population comprising a group of 34 patients with probable SDAT, a group of 20 patients with other dementias, and a group of 20 non-demented controls. A bilateral Sydney line was found to be significantly more frequent in the SDAT group than in the two other groups (p less than 0.01, sensitivity 30%, specificity 95%, positive predictive value 91%, negative predictive value 61%). A bilateral Sydney line was as frequent in the SDAT group as in Down's syndrome. The limit value of the index of transversality equal or superior to 31, which is considered as a feature of Down's syndrome, was significantly more frequent in the SDAT group than in the two other groups (right hand p less than 0.05, left hand p less than 0.02). A bilateral discriminant value of this index was also significantly more frequent in the SDAT group than in the two other groups (p less than 0.02), as was an index of transversality higher than 31 on at least one hand (p less than 0.01). In contrast with other reports, we haven't found significantly different frequencies of digital ulnar loops and true hypothenar patterns between the SDAT group and the two others.

Aged↗